LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B3A5_LEIMU
TriTrypDb:
LmxM.31.3220
Length:
626

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3A5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3A5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 622 626 PF00656 0.552
CLV_NRD_NRD_1 167 169 PF00675 0.676
CLV_NRD_NRD_1 202 204 PF00675 0.605
CLV_NRD_NRD_1 288 290 PF00675 0.395
CLV_NRD_NRD_1 360 362 PF00675 0.539
CLV_NRD_NRD_1 474 476 PF00675 0.616
CLV_NRD_NRD_1 75 77 PF00675 0.791
CLV_NRD_NRD_1 80 82 PF00675 0.728
CLV_PCSK_FUR_1 200 204 PF00082 0.612
CLV_PCSK_KEX2_1 167 169 PF00082 0.676
CLV_PCSK_KEX2_1 202 204 PF00082 0.605
CLV_PCSK_KEX2_1 360 362 PF00082 0.539
CLV_PCSK_KEX2_1 474 476 PF00082 0.616
CLV_PCSK_KEX2_1 75 77 PF00082 0.791
CLV_PCSK_KEX2_1 80 82 PF00082 0.728
CLV_PCSK_PC7_1 76 82 PF00082 0.659
CLV_PCSK_SKI1_1 105 109 PF00082 0.594
CLV_PCSK_SKI1_1 379 383 PF00082 0.565
CLV_PCSK_SKI1_1 583 587 PF00082 0.453
DEG_APCC_DBOX_1 231 239 PF00400 0.423
DEG_APCC_DBOX_1 484 492 PF00400 0.575
DEG_Nend_Nbox_1 1 3 PF02207 0.623
DEG_SCF_FBW7_1 419 425 PF00400 0.547
DEG_SCF_FBW7_1 431 438 PF00400 0.647
DEG_SPOP_SBC_1 161 165 PF00917 0.636
DEG_SPOP_SBC_1 264 268 PF00917 0.414
DOC_CDC14_PxL_1 380 388 PF14671 0.534
DOC_CKS1_1 169 174 PF01111 0.599
DOC_CKS1_1 403 408 PF01111 0.590
DOC_CKS1_1 419 424 PF01111 0.486
DOC_CYCLIN_yCln2_LP_2 493 499 PF00134 0.451
DOC_MAPK_DCC_7 479 488 PF00069 0.558
DOC_MAPK_gen_1 251 258 PF00069 0.448
DOC_MAPK_gen_1 289 296 PF00069 0.411
DOC_MAPK_gen_1 80 87 PF00069 0.726
DOC_MAPK_MEF2A_6 251 258 PF00069 0.455
DOC_MAPK_MEF2A_6 479 488 PF00069 0.558
DOC_PP1_RVXF_1 467 473 PF00149 0.494
DOC_PP2B_LxvP_1 178 181 PF13499 0.636
DOC_PP2B_LxvP_1 493 496 PF13499 0.448
DOC_PP4_FxxP_1 381 384 PF00568 0.537
DOC_PP4_MxPP_1 481 484 PF00568 0.601
DOC_USP7_MATH_1 161 165 PF00917 0.633
DOC_USP7_MATH_1 249 253 PF00917 0.544
DOC_USP7_MATH_1 320 324 PF00917 0.462
DOC_USP7_MATH_1 422 426 PF00917 0.705
DOC_USP7_MATH_1 435 439 PF00917 0.601
DOC_USP7_MATH_1 444 448 PF00917 0.577
DOC_USP7_MATH_1 557 561 PF00917 0.735
DOC_USP7_MATH_1 6 10 PF00917 0.709
DOC_USP7_MATH_1 90 94 PF00917 0.619
DOC_USP7_UBL2_3 298 302 PF12436 0.310
DOC_WW_Pin1_4 141 146 PF00397 0.718
DOC_WW_Pin1_4 153 158 PF00397 0.652
DOC_WW_Pin1_4 168 173 PF00397 0.523
DOC_WW_Pin1_4 184 189 PF00397 0.597
DOC_WW_Pin1_4 19 24 PF00397 0.644
DOC_WW_Pin1_4 191 196 PF00397 0.637
DOC_WW_Pin1_4 402 407 PF00397 0.686
DOC_WW_Pin1_4 418 423 PF00397 0.514
DOC_WW_Pin1_4 425 430 PF00397 0.605
DOC_WW_Pin1_4 431 436 PF00397 0.593
DOC_WW_Pin1_4 440 445 PF00397 0.564
DOC_WW_Pin1_4 452 457 PF00397 0.580
DOC_WW_Pin1_4 540 545 PF00397 0.588
LIG_14-3-3_CanoR_1 15 25 PF00244 0.672
LIG_14-3-3_CanoR_1 221 228 PF00244 0.562
LIG_14-3-3_CanoR_1 253 259 PF00244 0.502
LIG_14-3-3_CanoR_1 269 275 PF00244 0.487
LIG_14-3-3_CanoR_1 44 48 PF00244 0.548
LIG_14-3-3_CanoR_1 559 567 PF00244 0.634
LIG_14-3-3_CanoR_1 620 624 PF00244 0.560
LIG_14-3-3_CanoR_1 80 85 PF00244 0.627
LIG_Clathr_ClatBox_1 371 375 PF01394 0.524
LIG_Clathr_ClatBox_1 601 605 PF01394 0.552
LIG_DLG_GKlike_1 173 180 PF00625 0.629
LIG_eIF4E_1 233 239 PF01652 0.487
LIG_FHA_1 146 152 PF00498 0.554
LIG_FHA_1 169 175 PF00498 0.663
LIG_FHA_1 20 26 PF00498 0.739
LIG_FHA_1 32 38 PF00498 0.579
LIG_FHA_1 571 577 PF00498 0.623
LIG_FHA_2 255 261 PF00498 0.409
LIG_FHA_2 301 307 PF00498 0.407
LIG_FHA_2 313 319 PF00498 0.443
LIG_FHA_2 403 409 PF00498 0.634
LIG_FHA_2 432 438 PF00498 0.661
LIG_FHA_2 534 540 PF00498 0.650
LIG_FHA_2 620 626 PF00498 0.542
LIG_FHA_2 87 93 PF00498 0.732
LIG_LIR_Apic_2 163 169 PF02991 0.517
LIG_LIR_Apic_2 412 416 PF02991 0.636
LIG_LIR_Gen_1 257 264 PF02991 0.485
LIG_LIR_Gen_1 414 424 PF02991 0.576
LIG_LIR_Nem_3 299 304 PF02991 0.405
LIG_LIR_Nem_3 414 420 PF02991 0.574
LIG_LIR_Nem_3 574 580 PF02991 0.559
LIG_NRBOX 307 313 PF00104 0.439
LIG_PTB_Apo_2 137 144 PF02174 0.532
LIG_PTB_Phospho_1 137 143 PF10480 0.539
LIG_SH2_PTP2 293 296 PF00017 0.404
LIG_SH2_PTP2 513 516 PF00017 0.637
LIG_SH2_STAP1 126 130 PF00017 0.528
LIG_SH2_STAP1 332 336 PF00017 0.443
LIG_SH2_STAP1 387 391 PF00017 0.549
LIG_SH2_STAT3 214 217 PF00017 0.509
LIG_SH2_STAT5 136 139 PF00017 0.583
LIG_SH2_STAT5 293 296 PF00017 0.404
LIG_SH2_STAT5 413 416 PF00017 0.636
LIG_SH2_STAT5 513 516 PF00017 0.573
LIG_SH2_STAT5 580 583 PF00017 0.568
LIG_SH3_1 513 519 PF00018 0.563
LIG_SH3_3 117 123 PF00018 0.684
LIG_SH3_3 139 145 PF00018 0.569
LIG_SH3_3 166 172 PF00018 0.629
LIG_SH3_3 182 188 PF00018 0.599
LIG_SH3_3 189 195 PF00018 0.554
LIG_SH3_3 388 394 PF00018 0.550
LIG_SH3_3 400 406 PF00018 0.571
LIG_SH3_3 481 487 PF00018 0.557
LIG_SH3_3 506 512 PF00018 0.597
LIG_SH3_3 513 519 PF00018 0.539
LIG_SUMO_SIM_par_1 176 183 PF11976 0.632
LIG_SUMO_SIM_par_1 83 89 PF11976 0.552
LIG_TRAF2_1 111 114 PF00917 0.608
LIG_TRAF2_1 188 191 PF00917 0.535
LIG_TRAF2_1 303 306 PF00917 0.480
LIG_TRAF2_1 70 73 PF00917 0.661
LIG_WRC_WIRS_1 601 606 PF05994 0.618
LIG_WW_3 482 486 PF00397 0.620
MOD_CDK_SPK_2 168 173 PF00069 0.624
MOD_CDK_SPxxK_3 402 409 PF00069 0.590
MOD_CK1_1 134 140 PF00069 0.578
MOD_CK1_1 144 150 PF00069 0.544
MOD_CK1_1 176 182 PF00069 0.646
MOD_CK1_1 19 25 PF00069 0.730
MOD_CK1_1 226 232 PF00069 0.434
MOD_CK1_1 282 288 PF00069 0.444
MOD_CK1_1 31 37 PF00069 0.539
MOD_CK1_1 338 344 PF00069 0.470
MOD_CK1_1 402 408 PF00069 0.634
MOD_CK1_1 425 431 PF00069 0.603
MOD_CK1_1 443 449 PF00069 0.571
MOD_CK1_1 464 470 PF00069 0.645
MOD_CK1_1 83 89 PF00069 0.556
MOD_CK2_1 108 114 PF00069 0.606
MOD_CK2_1 125 131 PF00069 0.549
MOD_CK2_1 2 8 PF00069 0.609
MOD_CK2_1 254 260 PF00069 0.369
MOD_CK2_1 300 306 PF00069 0.412
MOD_CK2_1 312 318 PF00069 0.447
MOD_CK2_1 402 408 PF00069 0.634
MOD_CK2_1 431 437 PF00069 0.609
MOD_CK2_1 67 73 PF00069 0.805
MOD_CK2_1 86 92 PF00069 0.485
MOD_DYRK1A_RPxSP_1 168 172 PF00069 0.601
MOD_GlcNHglycan 110 113 PF01048 0.546
MOD_GlcNHglycan 182 185 PF01048 0.624
MOD_GlcNHglycan 225 228 PF01048 0.457
MOD_GlcNHglycan 281 284 PF01048 0.448
MOD_GlcNHglycan 318 321 PF01048 0.519
MOD_GlcNHglycan 4 7 PF01048 0.762
MOD_GlcNHglycan 446 449 PF01048 0.668
MOD_GlcNHglycan 450 453 PF01048 0.743
MOD_GlcNHglycan 546 549 PF01048 0.685
MOD_GlcNHglycan 554 557 PF01048 0.597
MOD_GlcNHglycan 69 72 PF01048 0.636
MOD_GlcNHglycan 8 11 PF01048 0.754
MOD_GSK3_1 141 148 PF00069 0.626
MOD_GSK3_1 15 22 PF00069 0.634
MOD_GSK3_1 176 183 PF00069 0.632
MOD_GSK3_1 2 9 PF00069 0.651
MOD_GSK3_1 263 270 PF00069 0.551
MOD_GSK3_1 279 286 PF00069 0.381
MOD_GSK3_1 28 35 PF00069 0.545
MOD_GSK3_1 312 319 PF00069 0.461
MOD_GSK3_1 322 329 PF00069 0.447
MOD_GSK3_1 418 425 PF00069 0.626
MOD_GSK3_1 427 434 PF00069 0.583
MOD_GSK3_1 440 447 PF00069 0.558
MOD_GSK3_1 448 455 PF00069 0.723
MOD_GSK3_1 457 464 PF00069 0.587
MOD_GSK3_1 540 547 PF00069 0.637
MOD_GSK3_1 86 93 PF00069 0.593
MOD_N-GLC_1 204 209 PF02516 0.606
MOD_N-GLC_1 67 72 PF02516 0.595
MOD_NEK2_1 2 7 PF00069 0.653
MOD_NEK2_1 220 225 PF00069 0.401
MOD_NEK2_1 274 279 PF00069 0.476
MOD_NEK2_1 457 462 PF00069 0.590
MOD_NEK2_1 470 475 PF00069 0.514
MOD_NEK2_1 491 496 PF00069 0.614
MOD_NEK2_1 588 593 PF00069 0.658
MOD_NEK2_2 422 427 PF00069 0.593
MOD_OFUCOSY 449 454 PF10250 0.578
MOD_PIKK_1 131 137 PF00454 0.621
MOD_PIKK_1 373 379 PF00454 0.452
MOD_PIKK_1 457 463 PF00454 0.608
MOD_PK_1 80 86 PF00069 0.597
MOD_PKA_1 80 86 PF00069 0.663
MOD_PKA_2 220 226 PF00069 0.399
MOD_PKA_2 270 276 PF00069 0.494
MOD_PKA_2 28 34 PF00069 0.741
MOD_PKA_2 43 49 PF00069 0.502
MOD_PKA_2 558 564 PF00069 0.631
MOD_PKA_2 619 625 PF00069 0.618
MOD_PKA_2 80 86 PF00069 0.663
MOD_Plk_1 131 137 PF00069 0.541
MOD_Plk_1 422 428 PF00069 0.595
MOD_Plk_1 435 441 PF00069 0.602
MOD_Plk_2-3 125 131 PF00069 0.529
MOD_Plk_4 173 179 PF00069 0.671
MOD_Plk_4 254 260 PF00069 0.435
MOD_Plk_4 335 341 PF00069 0.469
MOD_Plk_4 382 388 PF00069 0.521
MOD_Plk_4 399 405 PF00069 0.671
MOD_Plk_4 422 428 PF00069 0.595
MOD_Plk_4 499 505 PF00069 0.531
MOD_Plk_4 80 86 PF00069 0.523
MOD_ProDKin_1 141 147 PF00069 0.716
MOD_ProDKin_1 153 159 PF00069 0.655
MOD_ProDKin_1 168 174 PF00069 0.522
MOD_ProDKin_1 184 190 PF00069 0.597
MOD_ProDKin_1 19 25 PF00069 0.647
MOD_ProDKin_1 191 197 PF00069 0.638
MOD_ProDKin_1 402 408 PF00069 0.687
MOD_ProDKin_1 418 424 PF00069 0.516
MOD_ProDKin_1 425 431 PF00069 0.603
MOD_ProDKin_1 440 446 PF00069 0.561
MOD_ProDKin_1 452 458 PF00069 0.581
MOD_ProDKin_1 540 546 PF00069 0.591
TRG_DiLeu_BaEn_1 367 372 PF01217 0.514
TRG_DiLeu_BaLyEn_6 484 489 PF01217 0.576
TRG_ENDOCYTIC_2 293 296 PF00928 0.404
TRG_ER_diArg_1 166 168 PF00400 0.678
TRG_ER_diArg_1 200 203 PF00400 0.618
TRG_ER_diArg_1 250 253 PF00400 0.515
TRG_ER_diArg_1 360 363 PF00400 0.539
TRG_ER_diArg_1 74 76 PF00400 0.783
TRG_ER_diArg_1 79 81 PF00400 0.737
TRG_Pf-PMV_PEXEL_1 236 241 PF00026 0.490
TRG_Pf-PMV_PEXEL_1 302 306 PF00026 0.484

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVM2 Leptomonas seymouri 55% 100%
A0A3S7X620 Leishmania donovani 90% 100%
A4HKW7 Leishmania braziliensis 72% 100%
A4I8E7 Leishmania infantum 89% 100%
Q4Q4V0 Leishmania major 90% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS