Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B394_LEIMU

TriTrypDb:

LmxM.31.3100

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B394

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B394

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	261	265	PF00656	0.467
CLV_C14_Caspase3-7	99	103	PF00656	0.329
CLV_NRD_NRD_1	16	18	PF00675	0.500
CLV_NRD_NRD_1	45	47	PF00675	0.431
CLV_NRD_NRD_1	93	95	PF00675	0.491
CLV_PCSK_KEX2_1	45	47	PF00082	0.431
CLV_PCSK_KEX2_1	93	95	PF00082	0.491
CLV_PCSK_PC7_1	41	47	PF00082	0.433
CLV_PCSK_SKI1_1	271	275	PF00082	0.573
CLV_PCSK_SKI1_1	33	37	PF00082	0.600
CLV_PCSK_SKI1_1	94	98	PF00082	0.575
DEG_APCC_DBOX_1	93	101	PF00400	0.479
DEG_SPOP_SBC_1	55	59	PF00917	0.604
DOC_PP2B_LxvP_1	28	31	PF13499	0.413
DOC_USP7_MATH_1	131	135	PF00917	0.531
DOC_USP7_MATH_1	165	169	PF00917	0.733
DOC_USP7_MATH_1	230	234	PF00917	0.605
DOC_USP7_MATH_1	53	57	PF00917	0.633
DOC_WW_Pin1_4	220	225	PF00397	0.528
DOC_WW_Pin1_4	58	63	PF00397	0.658
LIG_14-3-3_CanoR_1	10	15	PF00244	0.429
LIG_14-3-3_CanoR_1	17	25	PF00244	0.401
LIG_BIR_II_1	1	5	PF00653	0.427
LIG_deltaCOP1_diTrp_1	264	273	PF00928	0.562
LIG_FHA_1	140	146	PF00498	0.653
LIG_FHA_1	34	40	PF00498	0.447
LIG_FHA_2	120	126	PF00498	0.543
LIG_FHA_2	65	71	PF00498	0.661
LIG_LIR_Gen_1	104	114	PF02991	0.358
LIG_LIR_Gen_1	199	207	PF02991	0.428
LIG_LIR_Nem_3	199	205	PF02991	0.425
LIG_NRBOX	202	208	PF00104	0.493
LIG_SH2_CRK	11	15	PF00017	0.414
LIG_SH2_STAT5	106	109	PF00017	0.464
LIG_SH2_STAT5	160	163	PF00017	0.484
LIG_SH2_STAT5	202	205	PF00017	0.489
LIG_SH3_3	120	126	PF00018	0.543
LIG_SUMO_SIM_anti_2	201	207	PF11976	0.433
LIG_TRAF2_1	191	194	PF00917	0.353
LIG_TRAF2_1	213	216	PF00917	0.478
LIG_UBA3_1	110	117	PF00899	0.448
LIG_UBA3_1	203	209	PF00899	0.344
MOD_CDK_SPxxK_3	220	227	PF00069	0.529
MOD_CK1_1	136	142	PF00069	0.518
MOD_CK1_1	164	170	PF00069	0.618
MOD_CK1_1	239	245	PF00069	0.652
MOD_CK1_1	56	62	PF00069	0.754
MOD_CK1_1	65	71	PF00069	0.578
MOD_CK2_1	119	125	PF00069	0.579
MOD_CK2_1	226	232	PF00069	0.608
MOD_GlcNHglycan	133	136	PF01048	0.675
MOD_GlcNHglycan	163	166	PF01048	0.738
MOD_GlcNHglycan	167	170	PF01048	0.673
MOD_GlcNHglycan	172	175	PF01048	0.573
MOD_GlcNHglycan	228	231	PF01048	0.655
MOD_GlcNHglycan	232	235	PF01048	0.603
MOD_GlcNHglycan	239	242	PF01048	0.613
MOD_GlcNHglycan	67	70	PF01048	0.548
MOD_GlcNHglycan	80	83	PF01048	0.625
MOD_GlcNHglycan	86	89	PF01048	0.420
MOD_GSK3_1	129	136	PF00069	0.683
MOD_GSK3_1	150	157	PF00069	0.676
MOD_GSK3_1	161	168	PF00069	0.621
MOD_GSK3_1	226	233	PF00069	0.663
MOD_GSK3_1	235	242	PF00069	0.546
MOD_GSK3_1	271	278	PF00069	0.603
MOD_GSK3_1	53	60	PF00069	0.732
MOD_GSK3_1	84	91	PF00069	0.522
MOD_GSK3_1	9	16	PF00069	0.593
MOD_NEK2_1	250	255	PF00069	0.547
MOD_NEK2_1	54	59	PF00069	0.752
MOD_NEK2_1	96	101	PF00069	0.318
MOD_OFUCOSY	15	20	PF10250	0.351
MOD_PIKK_1	101	107	PF00454	0.406
MOD_PIKK_1	129	135	PF00454	0.669
MOD_PKA_2	16	22	PF00069	0.448
MOD_PKA_2	226	232	PF00069	0.681
MOD_PKA_2	235	241	PF00069	0.620
MOD_PKA_2	65	71	PF00069	0.543
MOD_PKA_2	9	15	PF00069	0.518
MOD_PKB_1	269	277	PF00069	0.501
MOD_PKB_1	8	16	PF00069	0.514
MOD_Plk_1	139	145	PF00069	0.575
MOD_Plk_1	33	39	PF00069	0.601
MOD_ProDKin_1	220	226	PF00069	0.527
MOD_ProDKin_1	58	64	PF00069	0.659
TRG_DiLeu_BaEn_1	199	204	PF01217	0.477
TRG_DiLeu_BaEn_1	92	97	PF01217	0.418
TRG_ENDOCYTIC_2	106	109	PF00928	0.406
TRG_ENDOCYTIC_2	11	14	PF00928	0.429
TRG_ENDOCYTIC_2	202	205	PF00928	0.421
TRG_ER_diArg_1	217	220	PF00400	0.704
TRG_ER_diArg_1	269	272	PF00400	0.483
TRG_ER_diArg_1	8	11	PF00400	0.534
TRG_Pf-PMV_PEXEL_1	195	199	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	94	98	PF00026	0.485

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8D0	Leptomonas seymouri	30%	76%
A0A3Q8IG66	Leishmania donovani	80%	91%
A4I8D5	Leishmania infantum	81%	91%
Q4Q4W1	Leishmania major	79%	100%