Outer dynein arm docking complex protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Outer dynein arm docking complex protein 2, putative

Species:

Leishmania mexicana

UniProt:

E9B370_LEIMU

TriTrypDb:

LmxM.31.2900

Length:

618

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	1
GO:0005930	axoneme	2	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

Expansion

Sequence features

E9B370

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B370

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	196	200	PF00656	0.465
CLV_C14_Caspase3-7	360	364	PF00656	0.510
CLV_C14_Caspase3-7	567	571	PF00656	0.751
CLV_C14_Caspase3-7	74	78	PF00656	0.509
CLV_NRD_NRD_1	107	109	PF00675	0.273
CLV_NRD_NRD_1	163	165	PF00675	0.405
CLV_NRD_NRD_1	17	19	PF00675	0.470
CLV_NRD_NRD_1	274	276	PF00675	0.747
CLV_NRD_NRD_1	588	590	PF00675	0.511
CLV_NRD_NRD_1	607	609	PF00675	0.393
CLV_NRD_NRD_1	81	83	PF00675	0.454
CLV_NRD_NRD_1	88	90	PF00675	0.448
CLV_PCSK_KEX2_1	163	165	PF00082	0.420
CLV_PCSK_KEX2_1	17	19	PF00082	0.461
CLV_PCSK_KEX2_1	171	173	PF00082	0.443
CLV_PCSK_KEX2_1	181	183	PF00082	0.461
CLV_PCSK_KEX2_1	274	276	PF00082	0.719
CLV_PCSK_KEX2_1	81	83	PF00082	0.472
CLV_PCSK_KEX2_1	95	97	PF00082	0.455
CLV_PCSK_PC1ET2_1	171	173	PF00082	0.485
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.502
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.540
CLV_PCSK_SKI1_1	163	167	PF00082	0.405
CLV_PCSK_SKI1_1	209	213	PF00082	0.489
CLV_PCSK_SKI1_1	450	454	PF00082	0.561
CLV_PCSK_SKI1_1	595	599	PF00082	0.570
DEG_APCC_DBOX_1	95	103	PF00400	0.542
DEG_SPOP_SBC_1	288	292	PF00917	0.786
DOC_CKS1_1	539	544	PF01111	0.455
DOC_MAPK_gen_1	108	116	PF00069	0.556
DOC_MAPK_gen_1	150	158	PF00069	0.421
DOC_MAPK_gen_1	160	169	PF00069	0.418
DOC_MAPK_gen_1	589	596	PF00069	0.333
DOC_MAPK_MEF2A_6	160	169	PF00069	0.552
DOC_MAPK_MEF2A_6	459	467	PF00069	0.552
DOC_MAPK_MEF2A_6	589	596	PF00069	0.333
DOC_USP7_MATH_1	270	274	PF00917	0.713
DOC_USP7_MATH_1	279	283	PF00917	0.749
DOC_USP7_MATH_1	558	562	PF00917	0.729
DOC_USP7_UBL2_3	358	362	PF12436	0.552
DOC_WW_Pin1_4	490	495	PF00397	0.688
DOC_WW_Pin1_4	512	517	PF00397	0.688
DOC_WW_Pin1_4	529	534	PF00397	0.686
DOC_WW_Pin1_4	538	543	PF00397	0.660
LIG_14-3-3_CanoR_1	17	25	PF00244	0.518
LIG_14-3-3_CanoR_1	41	49	PF00244	0.419
LIG_14-3-3_CanoR_1	416	425	PF00244	0.509
LIG_14-3-3_CanoR_1	443	449	PF00244	0.536
LIG_14-3-3_CanoR_1	459	467	PF00244	0.351
LIG_14-3-3_CanoR_1	478	487	PF00244	0.556
LIG_14-3-3_CanoR_1	595	600	PF00244	0.619
LIG_Actin_WH2_2	347	364	PF00022	0.574
LIG_Actin_WH2_2	396	413	PF00022	0.559
LIG_BIR_II_1	1	5	PF00653	0.561
LIG_BRCT_BRCA1_1	483	487	PF00533	0.470
LIG_Clathr_ClatBox_1	304	308	PF01394	0.604
LIG_FHA_1	218	224	PF00498	0.583
LIG_FHA_1	299	305	PF00498	0.690
LIG_FHA_1	313	319	PF00498	0.608
LIG_FHA_1	325	331	PF00498	0.577
LIG_FHA_1	338	344	PF00498	0.495
LIG_FHA_1	405	411	PF00498	0.500
LIG_FHA_1	459	465	PF00498	0.461
LIG_FHA_1	480	486	PF00498	0.664
LIG_FHA_2	264	270	PF00498	0.472
LIG_FHA_2	290	296	PF00498	0.726
LIG_FHA_2	418	424	PF00498	0.527
LIG_FHA_2	453	459	PF00498	0.495
LIG_FHA_2	565	571	PF00498	0.738
LIG_FHA_2	57	63	PF00498	0.573
LIG_FHA_2	596	602	PF00498	0.628
LIG_LIR_Gen_1	422	433	PF02991	0.533
LIG_LIR_Gen_1	59	69	PF02991	0.468
LIG_LIR_Nem_3	342	348	PF02991	0.440
LIG_LIR_Nem_3	422	428	PF02991	0.371
LIG_LIR_Nem_3	59	64	PF02991	0.482
LIG_NRBOX	367	373	PF00104	0.574
LIG_PCNA_yPIPBox_3	344	358	PF02747	0.466
LIG_Rb_LxCxE_1	299	316	PF01857	0.595
LIG_SH2_CRK	348	352	PF00017	0.453
LIG_SH2_CRK	61	65	PF00017	0.466
LIG_SH2_GRB2like	219	222	PF00017	0.505
LIG_SH2_GRB2like	350	353	PF00017	0.479
LIG_SH2_NCK_1	425	429	PF00017	0.552
LIG_SH2_SRC	425	428	PF00017	0.568
LIG_SH2_SRC	61	64	PF00017	0.467
LIG_SH2_STAP1	219	223	PF00017	0.495
LIG_SH2_STAT3	219	222	PF00017	0.536
LIG_SH2_STAT3	574	577	PF00017	0.728
LIG_SH2_STAT5	219	222	PF00017	0.582
LIG_SH2_STAT5	337	340	PF00017	0.540
LIG_SH2_STAT5	350	353	PF00017	0.412
LIG_SH2_STAT5	63	66	PF00017	0.439
LIG_SH3_3	488	494	PF00018	0.455
LIG_SH3_3	530	536	PF00018	0.668
LIG_SUMO_SIM_anti_2	154	162	PF11976	0.435
LIG_TRAF2_1	266	269	PF00917	0.776
LIG_TRAF2_1	33	36	PF00917	0.314
LIG_TRAF2_1	455	458	PF00917	0.488
LIG_TRAF2_1	584	587	PF00917	0.381
LIG_TYR_ITSM	57	64	PF00017	0.580
LIG_UBA3_1	230	234	PF00899	0.583
LIG_UBA3_1	317	322	PF00899	0.598
MOD_CDK_SPK_2	490	495	PF00069	0.708
MOD_CK1_1	263	269	PF00069	0.718
MOD_CK1_1	474	480	PF00069	0.682
MOD_CK1_1	54	60	PF00069	0.603
MOD_CK1_1	544	550	PF00069	0.747
MOD_CK1_1	71	77	PF00069	0.563
MOD_CK2_1	263	269	PF00069	0.488
MOD_CK2_1	289	295	PF00069	0.769
MOD_CK2_1	452	458	PF00069	0.493
MOD_CK2_1	490	496	PF00069	0.688
MOD_CK2_1	581	587	PF00069	0.475
MOD_CK2_1	595	601	PF00069	0.589
MOD_GlcNHglycan	262	265	PF01048	0.583
MOD_GlcNHglycan	281	284	PF01048	0.705
MOD_GlcNHglycan	310	313	PF01048	0.557
MOD_GlcNHglycan	353	357	PF01048	0.569
MOD_GlcNHglycan	404	407	PF01048	0.412
MOD_GlcNHglycan	52	56	PF01048	0.503
MOD_GlcNHglycan	543	546	PF01048	0.653
MOD_GlcNHglycan	558	561	PF01048	0.514
MOD_GSK3_1	12	19	PF00069	0.600
MOD_GSK3_1	308	315	PF00069	0.554
MOD_GSK3_1	472	479	PF00069	0.643
MOD_GSK3_1	481	488	PF00069	0.683
MOD_GSK3_1	490	497	PF00069	0.592
MOD_GSK3_1	506	513	PF00069	0.686
MOD_N-GLC_1	343	348	PF02516	0.427
MOD_N-GLC_1	510	515	PF02516	0.777
MOD_NEK2_1	104	109	PF00069	0.461
MOD_NEK2_1	135	140	PF00069	0.555
MOD_NEK2_1	16	21	PF00069	0.579
MOD_NEK2_1	258	263	PF00069	0.687
MOD_NEK2_1	343	348	PF00069	0.475
MOD_NEK2_1	361	366	PF00069	0.568
MOD_NEK2_1	56	61	PF00069	0.534
MOD_PIKK_1	16	22	PF00454	0.521
MOD_PIKK_1	263	269	PF00454	0.476
MOD_PKA_2	16	22	PF00069	0.523
MOD_PKA_2	308	314	PF00069	0.608
MOD_PKA_2	40	46	PF00069	0.304
MOD_PKA_2	442	448	PF00069	0.544
MOD_PKA_2	458	464	PF00069	0.325
MOD_PKA_2	477	483	PF00069	0.568
MOD_PKA_2	485	491	PF00069	0.627
MOD_Plk_1	135	141	PF00069	0.557
MOD_Plk_1	343	349	PF00069	0.427
MOD_Plk_1	51	57	PF00069	0.557
MOD_Plk_1	569	575	PF00069	0.702
MOD_Plk_2-3	324	330	PF00069	0.629
MOD_Plk_4	300	306	PF00069	0.706
MOD_Plk_4	313	319	PF00069	0.525
MOD_Plk_4	569	575	PF00069	0.759
MOD_ProDKin_1	490	496	PF00069	0.693
MOD_ProDKin_1	512	518	PF00069	0.688
MOD_ProDKin_1	529	535	PF00069	0.685
MOD_ProDKin_1	538	544	PF00069	0.659
MOD_SUMO_for_1	356	359	PF00179	0.547
MOD_SUMO_for_1	49	52	PF00179	0.463
MOD_SUMO_rev_2	174	179	PF00179	0.532
MOD_SUMO_rev_2	227	236	PF00179	0.518
MOD_SUMO_rev_2	255	264	PF00179	0.665
MOD_SUMO_rev_2	355	364	PF00179	0.283
MOD_SUMO_rev_2	391	400	PF00179	0.593
TRG_DiLeu_BaEn_3	161	167	PF01217	0.551
TRG_DiLeu_BaEn_4	503	509	PF01217	0.690
TRG_DiLeu_BaLyEn_6	367	372	PF01217	0.542
TRG_ENDOCYTIC_2	348	351	PF00928	0.467
TRG_ENDOCYTIC_2	425	428	PF00928	0.520
TRG_ENDOCYTIC_2	61	64	PF00928	0.467
TRG_ER_diArg_1	16	18	PF00400	0.504
TRG_ER_diArg_1	163	165	PF00400	0.420
TRG_ER_diArg_1	81	83	PF00400	0.472
TRG_NLS_Bipartite_1	163	184	PF00514	0.439
TRG_NLS_MonoExtN_4	178	184	PF00514	0.476
TRG_Pf-PMV_PEXEL_1	370	374	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	387	391	PF00026	0.324

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8M7	Leptomonas seymouri	70%	97%
A0A0S4IU95	Bodo saltans	34%	100%
A0A1X0NRP3	Trypanosomatidae	49%	90%
A0A3Q8IH93	Leishmania donovani	94%	100%
A0A3R7MTI3	Trypanosoma rangeli	42%	96%
A4HKT2	Leishmania braziliensis	84%	100%
A4I8B1	Leishmania infantum	94%	100%
A8JF70	Chlamydomonas reinhardtii	27%	100%
D0AAI2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	97%
Q9U1E6	Leishmania major	94%	100%
V5BMI0	Trypanosoma cruzi	43%	95%