Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B331_LEIMU

TriTrypDb:

LmxM.31.2520

Length:

925

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B331

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B331

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	266	270	PF00656	0.781
CLV_C14_Caspase3-7	706	710	PF00656	0.829
CLV_NRD_NRD_1	178	180	PF00675	0.819
CLV_NRD_NRD_1	210	212	PF00675	0.866
CLV_NRD_NRD_1	277	279	PF00675	0.856
CLV_NRD_NRD_1	288	290	PF00675	0.675
CLV_NRD_NRD_1	311	313	PF00675	0.841
CLV_NRD_NRD_1	453	455	PF00675	0.856
CLV_NRD_NRD_1	459	461	PF00675	0.797
CLV_NRD_NRD_1	511	513	PF00675	0.794
CLV_NRD_NRD_1	514	516	PF00675	0.768
CLV_NRD_NRD_1	517	519	PF00675	0.727
CLV_NRD_NRD_1	521	523	PF00675	0.644
CLV_NRD_NRD_1	572	574	PF00675	0.663
CLV_NRD_NRD_1	646	648	PF00675	0.776
CLV_NRD_NRD_1	702	704	PF00675	0.749
CLV_NRD_NRD_1	794	796	PF00675	0.686
CLV_NRD_NRD_1	841	843	PF00675	0.763
CLV_NRD_NRD_1	857	859	PF00675	0.828
CLV_NRD_NRD_1	878	880	PF00675	0.747
CLV_PCSK_FUR_1	176	180	PF00082	0.792
CLV_PCSK_FUR_1	273	277	PF00082	0.867
CLV_PCSK_FUR_1	506	510	PF00082	0.824
CLV_PCSK_FUR_1	512	516	PF00082	0.774
CLV_PCSK_FUR_1	838	842	PF00082	0.692
CLV_PCSK_KEX2_1	178	180	PF00082	0.792
CLV_PCSK_KEX2_1	209	211	PF00082	0.863
CLV_PCSK_KEX2_1	273	275	PF00082	0.861
CLV_PCSK_KEX2_1	276	278	PF00082	0.824
CLV_PCSK_KEX2_1	287	289	PF00082	0.612
CLV_PCSK_KEX2_1	310	312	PF00082	0.838
CLV_PCSK_KEX2_1	453	455	PF00082	0.851
CLV_PCSK_KEX2_1	459	461	PF00082	0.792
CLV_PCSK_KEX2_1	508	510	PF00082	0.828
CLV_PCSK_KEX2_1	511	513	PF00082	0.780
CLV_PCSK_KEX2_1	514	516	PF00082	0.747
CLV_PCSK_KEX2_1	517	519	PF00082	0.701
CLV_PCSK_KEX2_1	521	523	PF00082	0.604
CLV_PCSK_KEX2_1	572	574	PF00082	0.652
CLV_PCSK_KEX2_1	645	647	PF00082	0.770
CLV_PCSK_KEX2_1	702	704	PF00082	0.749
CLV_PCSK_KEX2_1	794	796	PF00082	0.821
CLV_PCSK_KEX2_1	840	842	PF00082	0.764
CLV_PCSK_KEX2_1	878	880	PF00082	0.754
CLV_PCSK_KEX2_1	904	906	PF00082	0.754
CLV_PCSK_PC1ET2_1	904	906	PF00082	0.773
CLV_PCSK_PC7_1	273	279	PF00082	0.860
CLV_PCSK_PC7_1	504	510	PF00082	0.787
CLV_PCSK_PC7_1	517	523	PF00082	0.634
CLV_PCSK_SKI1_1	45	49	PF00082	0.711
CLV_PCSK_SKI1_1	694	698	PF00082	0.666
CLV_PCSK_SKI1_1	748	752	PF00082	0.656
CLV_PCSK_SKI1_1	795	799	PF00082	0.625
DEG_Nend_Nbox_1	1	3	PF02207	0.782
DEG_SCF_FBW7_1	383	390	PF00400	0.647
DEG_SPOP_SBC_1	444	448	PF00917	0.789
DEG_SPOP_SBC_1	464	468	PF00917	0.545
DEG_SPOP_SBC_1	527	531	PF00917	0.681
DEG_SPOP_SBC_1	891	895	PF00917	0.767
DOC_ANK_TNKS_1	654	661	PF00023	0.576
DOC_CKS1_1	755	760	PF01111	0.721
DOC_MAPK_MEF2A_6	294	301	PF00069	0.569
DOC_PP1_SILK_1	565	570	PF00149	0.541
DOC_PP2B_LxvP_1	123	126	PF13499	0.514
DOC_PP2B_LxvP_1	391	394	PF13499	0.545
DOC_PP2B_LxvP_1	78	81	PF13499	0.508
DOC_PP4_FxxP_1	108	111	PF00568	0.729
DOC_USP7_MATH_1	11	15	PF00917	0.816
DOC_USP7_MATH_1	146	150	PF00917	0.759
DOC_USP7_MATH_1	158	162	PF00917	0.666
DOC_USP7_MATH_1	192	196	PF00917	0.778
DOC_USP7_MATH_1	240	244	PF00917	0.782
DOC_USP7_MATH_1	29	33	PF00917	0.485
DOC_USP7_MATH_1	345	349	PF00917	0.846
DOC_USP7_MATH_1	370	374	PF00917	0.788
DOC_USP7_MATH_1	379	383	PF00917	0.663
DOC_USP7_MATH_1	462	466	PF00917	0.798
DOC_USP7_MATH_1	499	503	PF00917	0.800
DOC_USP7_MATH_1	527	531	PF00917	0.875
DOC_USP7_MATH_1	540	544	PF00917	0.637
DOC_USP7_MATH_1	63	67	PF00917	0.805
DOC_USP7_MATH_1	634	638	PF00917	0.595
DOC_USP7_MATH_1	651	655	PF00917	0.763
DOC_USP7_MATH_1	716	720	PF00917	0.758
DOC_USP7_MATH_1	736	740	PF00917	0.525
DOC_USP7_MATH_1	785	789	PF00917	0.840
DOC_USP7_MATH_1	797	801	PF00917	0.638
DOC_WW_Pin1_4	147	152	PF00397	0.713
DOC_WW_Pin1_4	160	165	PF00397	0.621
DOC_WW_Pin1_4	168	173	PF00397	0.744
DOC_WW_Pin1_4	184	189	PF00397	0.668
DOC_WW_Pin1_4	289	294	PF00397	0.870
DOC_WW_Pin1_4	360	365	PF00397	0.848
DOC_WW_Pin1_4	383	388	PF00397	0.773
DOC_WW_Pin1_4	425	430	PF00397	0.646
DOC_WW_Pin1_4	435	440	PF00397	0.699
DOC_WW_Pin1_4	458	463	PF00397	0.799
DOC_WW_Pin1_4	543	548	PF00397	0.684
DOC_WW_Pin1_4	58	63	PF00397	0.788
DOC_WW_Pin1_4	582	587	PF00397	0.569
DOC_WW_Pin1_4	647	652	PF00397	0.797
DOC_WW_Pin1_4	66	71	PF00397	0.720
DOC_WW_Pin1_4	728	733	PF00397	0.754
DOC_WW_Pin1_4	754	759	PF00397	0.653
DOC_WW_Pin1_4	847	852	PF00397	0.863
DOC_WW_Pin1_4	877	882	PF00397	0.825
LIG_14-3-3_CanoR_1	287	296	PF00244	0.783
LIG_14-3-3_CanoR_1	453	462	PF00244	0.794
LIG_14-3-3_CanoR_1	478	488	PF00244	0.697
LIG_14-3-3_CanoR_1	525	535	PF00244	0.750
LIG_14-3-3_CanoR_1	735	743	PF00244	0.664
LIG_CtBP_PxDLS_1	296	300	PF00389	0.559
LIG_CtBP_PxDLS_1	775	779	PF00389	0.773
LIG_FHA_1	132	138	PF00498	0.749
LIG_FHA_1	388	394	PF00498	0.782
LIG_FHA_1	661	667	PF00498	0.599
LIG_FHA_1	744	750	PF00498	0.706
LIG_FHA_1	755	761	PF00498	0.653
LIG_FHA_2	232	238	PF00498	0.822
LIG_FHA_2	488	494	PF00498	0.569
LIG_Integrin_RGD_1	179	181	PF01839	0.875
LIG_LIR_Apic_2	85	89	PF02991	0.597
LIG_LIR_LC3C_4	389	393	PF02991	0.551
LIG_LIR_LC3C_4	403	407	PF02991	0.528
LIG_MYND_1	394	398	PF01753	0.646
LIG_Pex14_2	235	239	PF04695	0.863
LIG_Pex14_2	697	701	PF04695	0.823
LIG_REV1ctd_RIR_1	568	577	PF16727	0.831
LIG_SH2_CRK	100	104	PF00017	0.606
LIG_SH2_CRK	86	90	PF00017	0.716
LIG_SH2_NCK_1	223	227	PF00017	0.790
LIG_SH2_STAP1	484	488	PF00017	0.737
LIG_SH2_STAP1	610	614	PF00017	0.759
LIG_SH2_STAT3	106	109	PF00017	0.557
LIG_SH2_STAT3	153	156	PF00017	0.576
LIG_SH3_2	758	763	PF14604	0.733
LIG_SH3_3	118	124	PF00018	0.749
LIG_SH3_3	145	151	PF00018	0.566
LIG_SH3_3	249	255	PF00018	0.786
LIG_SH3_3	290	296	PF00018	0.861
LIG_SH3_3	327	333	PF00018	0.577
LIG_SH3_3	392	398	PF00018	0.809
LIG_SH3_3	403	409	PF00018	0.647
LIG_SH3_3	434	440	PF00018	0.638
LIG_SH3_3	53	59	PF00018	0.721
LIG_SH3_3	663	669	PF00018	0.573
LIG_SH3_3	755	761	PF00018	0.731
LIG_SH3_3	77	83	PF00018	0.656
LIG_SH3_3	85	91	PF00018	0.585
LIG_SUMO_SIM_par_1	397	403	PF11976	0.829
LIG_TRAF2_1	592	595	PF00917	0.778
LIG_UBA3_1	696	705	PF00899	0.746
LIG_WW_3	216	220	PF00397	0.564
LIG_WW_3	522	526	PF00397	0.586
MOD_CDC14_SPxK_1	363	366	PF00782	0.845
MOD_CDK_SPK_2	168	173	PF00069	0.783
MOD_CDK_SPK_2	289	294	PF00069	0.656
MOD_CDK_SPxK_1	360	366	PF00069	0.849
MOD_CDK_SPxK_1	582	588	PF00069	0.571
MOD_CDK_SPxK_1	647	653	PF00069	0.793
MOD_CDK_SPxxK_3	160	167	PF00069	0.669
MOD_CDK_SPxxK_3	728	735	PF00069	0.641
MOD_CK1_1	149	155	PF00069	0.735
MOD_CK1_1	171	177	PF00069	0.630
MOD_CK1_1	292	298	PF00069	0.778
MOD_CK1_1	463	469	PF00069	0.794
MOD_CK1_1	482	488	PF00069	0.552
MOD_CK1_1	500	506	PF00069	0.592
MOD_CK1_1	526	532	PF00069	0.855
MOD_CK1_1	542	548	PF00069	0.596
MOD_CK1_1	636	642	PF00069	0.852
MOD_CK1_1	66	72	PF00069	0.735
MOD_CK1_1	690	696	PF00069	0.758
MOD_CK1_1	724	730	PF00069	0.716
MOD_CK1_1	731	737	PF00069	0.667
MOD_CK1_1	739	745	PF00069	0.757
MOD_CK1_1	777	783	PF00069	0.677
MOD_CK1_1	887	893	PF00069	0.824
MOD_CK1_1	894	900	PF00069	0.778
MOD_CK2_1	231	237	PF00069	0.819
MOD_CK2_1	280	286	PF00069	0.663
MOD_CK2_1	292	298	PF00069	0.755
MOD_CK2_1	487	493	PF00069	0.781
MOD_CK2_1	551	557	PF00069	0.686
MOD_CK2_1	634	640	PF00069	0.567
MOD_Cter_Amidation	271	274	PF01082	0.871
MOD_Cter_Amidation	515	518	PF01082	0.867
MOD_Cter_Amidation	519	522	PF01082	0.772
MOD_Cter_Amidation	838	841	PF01082	0.616
MOD_Cter_Amidation	856	859	PF01082	0.623
MOD_DYRK1A_RPxSP_1	58	62	PF00069	0.649
MOD_GlcNHglycan	13	16	PF01048	0.740
MOD_GlcNHglycan	144	147	PF01048	0.785
MOD_GlcNHglycan	160	163	PF01048	0.693
MOD_GlcNHglycan	173	176	PF01048	0.657
MOD_GlcNHglycan	189	192	PF01048	0.858
MOD_GlcNHglycan	196	199	PF01048	0.758
MOD_GlcNHglycan	25	28	PF01048	0.618
MOD_GlcNHglycan	282	285	PF01048	0.579
MOD_GlcNHglycan	31	34	PF01048	0.539
MOD_GlcNHglycan	334	337	PF01048	0.862
MOD_GlcNHglycan	356	359	PF01048	0.699
MOD_GlcNHglycan	374	377	PF01048	0.612
MOD_GlcNHglycan	402	405	PF01048	0.678
MOD_GlcNHglycan	416	419	PF01048	0.649
MOD_GlcNHglycan	462	465	PF01048	0.845
MOD_GlcNHglycan	468	471	PF01048	0.791
MOD_GlcNHglycan	493	496	PF01048	0.825
MOD_GlcNHglycan	499	502	PF01048	0.795
MOD_GlcNHglycan	525	528	PF01048	0.783
MOD_GlcNHglycan	542	545	PF01048	0.690
MOD_GlcNHglycan	575	578	PF01048	0.804
MOD_GlcNHglycan	582	585	PF01048	0.779
MOD_GlcNHglycan	65	68	PF01048	0.727
MOD_GlcNHglycan	660	663	PF01048	0.854
MOD_GlcNHglycan	684	687	PF01048	0.744
MOD_GlcNHglycan	726	729	PF01048	0.749
MOD_GlcNHglycan	738	741	PF01048	0.822
MOD_GlcNHglycan	795	798	PF01048	0.556
MOD_GlcNHglycan	833	836	PF01048	0.791
MOD_GlcNHglycan	859	862	PF01048	0.867
MOD_GlcNHglycan	864	867	PF01048	0.637
MOD_GlcNHglycan	9	12	PF01048	0.723
MOD_GlcNHglycan	906	909	PF01048	0.821
MOD_GlcNHglycan	911	914	PF01048	0.731
MOD_GSK3_1	127	134	PF00069	0.782
MOD_GSK3_1	138	145	PF00069	0.698
MOD_GSK3_1	156	163	PF00069	0.663
MOD_GSK3_1	221	228	PF00069	0.771
MOD_GSK3_1	350	357	PF00069	0.798
MOD_GSK3_1	360	367	PF00069	0.705
MOD_GSK3_1	379	386	PF00069	0.578
MOD_GSK3_1	431	438	PF00069	0.668
MOD_GSK3_1	454	461	PF00069	0.851
MOD_GSK3_1	462	469	PF00069	0.761
MOD_GSK3_1	478	485	PF00069	0.573
MOD_GSK3_1	487	494	PF00069	0.630
MOD_GSK3_1	523	530	PF00069	0.759
MOD_GSK3_1	539	546	PF00069	0.572
MOD_GSK3_1	647	654	PF00069	0.772
MOD_GSK3_1	65	72	PF00069	0.808
MOD_GSK3_1	677	684	PF00069	0.800
MOD_GSK3_1	7	14	PF00069	0.614
MOD_GSK3_1	724	731	PF00069	0.683
MOD_GSK3_1	735	742	PF00069	0.687
MOD_GSK3_1	744	751	PF00069	0.710
MOD_GSK3_1	793	800	PF00069	0.684
MOD_GSK3_1	857	864	PF00069	0.789
MOD_GSK3_1	882	889	PF00069	0.728
MOD_GSK3_1	890	897	PF00069	0.753
MOD_LATS_1	452	458	PF00433	0.817
MOD_N-GLC_1	156	161	PF02516	0.574
MOD_N-GLC_1	221	226	PF02516	0.589
MOD_N-GLC_1	370	375	PF02516	0.803
MOD_N-GLC_1	551	556	PF02516	0.834
MOD_N-GLC_1	721	726	PF02516	0.751
MOD_N-GLC_1	743	748	PF02516	0.770
MOD_N-GLC_1	842	847	PF02516	0.680
MOD_N-GLC_2	44	46	PF02516	0.697
MOD_N-GLC_2	886	888	PF02516	0.783
MOD_NEK2_1	132	137	PF00069	0.535
MOD_NEK2_1	23	28	PF00069	0.559
MOD_NEK2_1	344	349	PF00069	0.789
MOD_NEK2_1	602	607	PF00069	0.715
MOD_NEK2_1	7	12	PF00069	0.601
MOD_NEK2_1	776	781	PF00069	0.806
MOD_NEK2_1	793	798	PF00069	0.552
MOD_NEK2_1	882	887	PF00069	0.785
MOD_NEK2_2	610	615	PF00069	0.664
MOD_PIKK_1	138	144	PF00454	0.835
MOD_PIKK_1	225	231	PF00454	0.785
MOD_PIKK_1	602	608	PF00454	0.547
MOD_PIKK_1	824	830	PF00454	0.728
MOD_PKA_1	287	293	PF00069	0.785
MOD_PKA_1	904	910	PF00069	0.774
MOD_PKA_2	218	224	PF00069	0.578
MOD_PKA_2	287	293	PF00069	0.859
MOD_PKA_2	5	11	PF00069	0.506
MOD_PKA_2	734	740	PF00069	0.742
MOD_PKA_2	793	799	PF00069	0.666
MOD_PKA_2	857	863	PF00069	0.864
MOD_PKA_2	904	910	PF00069	0.774
MOD_PKB_1	840	848	PF00069	0.708
MOD_Plk_1	551	557	PF00069	0.835
MOD_Plk_1	594	600	PF00069	0.701
MOD_Plk_1	610	616	PF00069	0.637
MOD_Plk_1	721	727	PF00069	0.753
MOD_Plk_4	387	393	PF00069	0.763
MOD_Plk_4	594	600	PF00069	0.701
MOD_ProDKin_1	147	153	PF00069	0.715
MOD_ProDKin_1	160	166	PF00069	0.620
MOD_ProDKin_1	168	174	PF00069	0.746
MOD_ProDKin_1	184	190	PF00069	0.671
MOD_ProDKin_1	289	295	PF00069	0.870
MOD_ProDKin_1	360	366	PF00069	0.849
MOD_ProDKin_1	383	389	PF00069	0.775
MOD_ProDKin_1	425	431	PF00069	0.647
MOD_ProDKin_1	435	441	PF00069	0.701
MOD_ProDKin_1	458	464	PF00069	0.797
MOD_ProDKin_1	543	549	PF00069	0.684
MOD_ProDKin_1	58	64	PF00069	0.790
MOD_ProDKin_1	582	588	PF00069	0.571
MOD_ProDKin_1	647	653	PF00069	0.800
MOD_ProDKin_1	66	72	PF00069	0.720
MOD_ProDKin_1	728	734	PF00069	0.756
MOD_ProDKin_1	754	760	PF00069	0.656
MOD_ProDKin_1	847	853	PF00069	0.855
MOD_ProDKin_1	877	883	PF00069	0.825
MOD_SUMO_rev_2	298	308	PF00179	0.783
TRG_ENDOCYTIC_2	100	103	PF00928	0.784
TRG_ER_diArg_1	176	179	PF00400	0.792
TRG_ER_diArg_1	209	211	PF00400	0.766
TRG_ER_diArg_1	273	276	PF00400	0.865
TRG_ER_diArg_1	287	289	PF00400	0.612
TRG_ER_diArg_1	310	312	PF00400	0.784
TRG_ER_diArg_1	453	456	PF00400	0.853
TRG_ER_diArg_1	506	509	PF00400	0.843
TRG_ER_diArg_1	510	512	PF00400	0.821
TRG_ER_diArg_1	514	517	PF00400	0.767
TRG_ER_diArg_1	521	523	PF00400	0.603
TRG_ER_diArg_1	532	535	PF00400	0.626
TRG_ER_diArg_1	571	573	PF00400	0.665
TRG_ER_diArg_1	645	647	PF00400	0.577
TRG_ER_diArg_1	701	703	PF00400	0.745
TRG_ER_diArg_1	793	795	PF00400	0.685
TRG_ER_diArg_1	838	841	PF00400	0.686
TRG_NLS_MonoExtN_4	795	802	PF00514	0.760

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJG2	Leishmania donovani	81%	100%
A4HKP2	Leishmania braziliensis	52%	100%
A4I873	Leishmania infantum	82%	100%
Q4Q523	Leishmania major	79%	100%