LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B2Y5_LEIMU
TriTrypDb:
LmxM.31.2050
Length:
91

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2Y5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2Y5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 32 36 PF00656 0.690
DEG_Nend_UBRbox_1 1 4 PF02207 0.346
DEG_SCF_FBW7_1 59 66 PF00400 0.601
DOC_PP1_RVXF_1 5 11 PF00149 0.411
DOC_WW_Pin1_4 59 64 PF00397 0.681
LIG_14-3-3_CanoR_1 2 10 PF00244 0.411
LIG_14-3-3_CanoR_1 24 33 PF00244 0.675
LIG_FHA_1 25 31 PF00498 0.671
LIG_FHA_2 30 36 PF00498 0.691
LIG_IBAR_NPY_1 76 78 PF08397 0.672
LIG_Pex14_2 18 22 PF04695 0.513
LIG_PTB_Apo_2 73 80 PF02174 0.623
LIG_PTB_Phospho_1 73 79 PF10480 0.623
LIG_SH2_STAT3 78 81 PF00017 0.682
LIG_SH2_STAT5 9 12 PF00017 0.364
LIG_SUMO_SIM_anti_2 13 18 PF11976 0.398
MOD_CK1_1 67 73 PF00069 0.779
MOD_CK2_1 33 39 PF00069 0.556
MOD_GlcNHglycan 59 62 PF01048 0.523
MOD_GSK3_1 29 36 PF00069 0.571
MOD_GSK3_1 59 66 PF00069 0.776
MOD_N-GLC_1 85 90 PF02516 0.477
MOD_NEK2_1 1 6 PF00069 0.320
MOD_NEK2_1 10 15 PF00069 0.323
MOD_NEK2_1 64 69 PF00069 0.743
MOD_PKA_2 1 7 PF00069 0.346
MOD_PKA_2 23 29 PF00069 0.660
MOD_ProDKin_1 59 65 PF00069 0.681
MOD_SUMO_for_1 37 40 PF00179 0.670

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I632 Leptomonas seymouri 74% 100%
A0A3Q8IGU3 Leishmania donovani 90% 100%
A4HKJ5 Leishmania braziliensis 81% 100%
A4I827 Leishmania infantum 90% 100%
Q4Q571 Leishmania major 91% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS