LeishMANIAdb
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Voltage-dependent P/Q-type calcium channel subunit alpha-1A-like

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Voltage-dependent P/Q-type calcium channel subunit alpha-1A-like
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B2X9_LEIMU
TriTrypDb:
LmxM.31.1990
Length:
108

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2X9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2X9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 104 106 PF00675 0.747
CLV_NRD_NRD_1 38 40 PF00675 0.664
CLV_NRD_NRD_1 67 69 PF00675 0.765
CLV_PCSK_KEX2_1 104 106 PF00082 0.747
CLV_PCSK_KEX2_1 14 16 PF00082 0.606
CLV_PCSK_KEX2_1 67 69 PF00082 0.765
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.752
DOC_ANK_TNKS_1 67 74 PF00023 0.763
LIG_BIR_II_1 1 5 PF00653 0.806
LIG_LIR_Apic_2 96 101 PF02991 0.715
LIG_PROFILIN_1 89 95 PF00235 0.693
LIG_SH2_CRK 98 102 PF00017 0.714
LIG_SH2_NCK_1 98 102 PF00017 0.714
LIG_SH3_1 87 93 PF00018 0.686
LIG_SH3_3 6 12 PF00018 0.766
LIG_SH3_3 86 92 PF00018 0.725
LIG_WW_2 92 95 PF00397 0.687
MOD_GlcNHglycan 32 35 PF01048 0.755
MOD_GlcNHglycan 69 72 PF01048 0.599
MOD_PIKK_1 45 51 PF00454 0.643
MOD_PKA_1 67 73 PF00069 0.552
MOD_PKA_2 45 51 PF00069 0.528
MOD_PKA_2 67 73 PF00069 0.554
TRG_ER_diArg_1 103 105 PF00400 0.736
TRG_ER_diArg_1 17 20 PF00400 0.757
TRG_ER_diArg_1 66 68 PF00400 0.753

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X5P3 Leishmania donovani 69% 86%
A4HKI9 Leishmania braziliensis 67% 100%
A4I821 Leishmania infantum 73% 90%
Q4Q577 Leishmania major 82% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS