Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2X7_LEIMU

TriTrypDb:

LmxM.31.1975

Length:

148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2X7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2X7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	145	147	PF00675	0.553
CLV_NRD_NRD_1	30	32	PF00675	0.530
CLV_NRD_NRD_1	60	62	PF00675	0.561
CLV_PCSK_FUR_1	6	10	PF00082	0.485
CLV_PCSK_KEX2_1	102	104	PF00082	0.574
CLV_PCSK_KEX2_1	144	146	PF00082	0.555
CLV_PCSK_KEX2_1	29	31	PF00082	0.518
CLV_PCSK_KEX2_1	34	36	PF00082	0.574
CLV_PCSK_KEX2_1	59	61	PF00082	0.566
CLV_PCSK_KEX2_1	8	10	PF00082	0.485
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.574
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.536
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.518
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.574
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.566
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.485
CLV_PCSK_PC7_1	30	36	PF00082	0.553
CLV_PCSK_SKI1_1	137	141	PF00082	0.542
DOC_USP7_MATH_1	122	126	PF00917	0.640
DOC_USP7_MATH_1	64	68	PF00917	0.742
DOC_USP7_MATH_1	89	93	PF00917	0.630
DOC_USP7_UBL2_3	137	141	PF12436	0.534
DOC_USP7_UBL2_3	4	8	PF12436	0.487
DOC_WW_Pin1_4	82	87	PF00397	0.596
LIG_14-3-3_CanoR_1	103	111	PF00244	0.638
LIG_14-3-3_CanoR_1	123	129	PF00244	0.463
LIG_BIR_III_2	126	130	PF00653	0.597
LIG_FHA_2	37	43	PF00498	0.684
LIG_FHA_2	70	76	PF00498	0.558
LIG_LIR_Gen_1	108	119	PF02991	0.560
LIG_LIR_Nem_3	108	114	PF02991	0.499
LIG_SH2_STAT5	12	15	PF00017	0.464
LIG_SH2_STAT5	26	29	PF00017	0.486
MOD_CK1_1	105	111	PF00069	0.648
MOD_CK1_1	118	124	PF00069	0.459
MOD_CK1_1	36	42	PF00069	0.679
MOD_CK2_1	107	113	PF00069	0.503
MOD_CK2_1	36	42	PF00069	0.704
MOD_CK2_1	69	75	PF00069	0.555
MOD_GlcNHglycan	117	120	PF01048	0.628
MOD_GlcNHglycan	131	135	PF01048	0.558
MOD_GSK3_1	114	121	PF00069	0.676
MOD_GSK3_1	135	142	PF00069	0.519
MOD_GSK3_1	85	92	PF00069	0.620
MOD_NEK2_1	114	119	PF00069	0.484
MOD_NEK2_1	135	140	PF00069	0.438
MOD_NEK2_2	139	144	PF00069	0.522
MOD_PKA_1	102	108	PF00069	0.545
MOD_PKA_2	102	108	PF00069	0.545
MOD_PKA_2	122	128	PF00069	0.543
MOD_PKA_2	22	28	PF00069	0.473
MOD_PKA_2	36	42	PF00069	0.602
MOD_Plk_1	130	136	PF00069	0.586
MOD_Plk_1	64	70	PF00069	0.558
MOD_Plk_4	22	28	PF00069	0.473
MOD_ProDKin_1	82	88	PF00069	0.597
TRG_ER_diArg_1	60	62	PF00400	0.454
TRG_NLS_MonoCore_2	57	62	PF00514	0.571
TRG_NLS_MonoExtC_3	57	63	PF00514	0.572
TRG_NLS_MonoExtN_4	141	148	PF00514	0.526
TRG_NLS_MonoExtN_4	2	7	PF00514	0.515
TRG_NLS_MonoExtN_4	57	62	PF00514	0.557
TRG_Pf-PMV_PEXEL_1	17	22	PF00026	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXV1	Leptomonas seymouri	49%	100%
A0A3Q8IJB3	Leishmania donovani	82%	100%
A4HKI7	Leishmania braziliensis	67%	100%
A4I819	Leishmania infantum	82%	100%
Q4Q579	Leishmania major	79%	100%