Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B2X5_LEIMU

TriTrypDb:

LmxM.31.1965

Length:

454

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2X5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2X5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	333	337	PF00656	0.614
CLV_NRD_NRD_1	362	364	PF00675	0.670
CLV_NRD_NRD_1	397	399	PF00675	0.646
CLV_NRD_NRD_1	54	56	PF00675	0.699
CLV_PCSK_FUR_1	395	399	PF00082	0.641
CLV_PCSK_KEX2_1	362	364	PF00082	0.685
CLV_PCSK_KEX2_1	368	370	PF00082	0.646
CLV_PCSK_KEX2_1	397	399	PF00082	0.646
CLV_PCSK_KEX2_1	54	56	PF00082	0.699
CLV_PCSK_PC1ET2_1	368	370	PF00082	0.597
CLV_PCSK_SKI1_1	183	187	PF00082	0.549
CLV_PCSK_SKI1_1	431	435	PF00082	0.601
DEG_Nend_UBRbox_2	1	3	PF02207	0.613
DEG_SCF_TRCP1_1	446	452	PF00400	0.604
DEG_SPOP_SBC_1	229	233	PF00917	0.536
DOC_ANK_TNKS_1	117	124	PF00023	0.566
DOC_CKS1_1	65	70	PF01111	0.684
DOC_CYCLIN_yCln2_LP_2	108	114	PF00134	0.483
DOC_MAPK_gen_1	240	248	PF00069	0.666
DOC_PP2B_LxvP_1	286	289	PF13499	0.519
DOC_PP4_FxxP_1	253	256	PF00568	0.537
DOC_PP4_FxxP_1	315	318	PF00568	0.728
DOC_USP7_MATH_1	116	120	PF00917	0.659
DOC_USP7_MATH_1	145	149	PF00917	0.664
DOC_USP7_MATH_1	196	200	PF00917	0.630
DOC_USP7_MATH_1	22	26	PF00917	0.532
DOC_USP7_MATH_1	244	248	PF00917	0.518
DOC_USP7_MATH_1	276	280	PF00917	0.637
DOC_USP7_MATH_1	281	285	PF00917	0.660
DOC_USP7_MATH_1	318	322	PF00917	0.660
DOC_USP7_MATH_1	378	382	PF00917	0.588
DOC_USP7_MATH_1	387	391	PF00917	0.632
DOC_USP7_MATH_1	66	70	PF00917	0.569
DOC_USP7_MATH_2	234	240	PF00917	0.579
DOC_USP7_UBL2_3	131	135	PF12436	0.549
DOC_WW_Pin1_4	12	17	PF00397	0.692
DOC_WW_Pin1_4	169	174	PF00397	0.653
DOC_WW_Pin1_4	230	235	PF00397	0.599
DOC_WW_Pin1_4	314	319	PF00397	0.615
DOC_WW_Pin1_4	374	379	PF00397	0.566
DOC_WW_Pin1_4	64	69	PF00397	0.691
LIG_14-3-3_CanoR_1	211	216	PF00244	0.650
LIG_14-3-3_CanoR_1	240	248	PF00244	0.666
LIG_14-3-3_CanoR_1	282	289	PF00244	0.644
LIG_14-3-3_CanoR_1	316	326	PF00244	0.693
LIG_14-3-3_CanoR_1	376	385	PF00244	0.625
LIG_14-3-3_CanoR_1	391	395	PF00244	0.575
LIG_14-3-3_CanoR_1	397	403	PF00244	0.605
LIG_BRCT_BRCA1_1	309	313	PF00533	0.643
LIG_BRCT_BRCA1_1	336	340	PF00533	0.618
LIG_CaM_IQ_9	417	433	PF13499	0.591
LIG_FHA_1	255	261	PF00498	0.530
LIG_FHA_1	35	41	PF00498	0.530
LIG_FHA_2	16	22	PF00498	0.632
LIG_FHA_2	322	328	PF00498	0.645
LIG_FHA_2	55	61	PF00498	0.679
LIG_GBD_Chelix_1	322	330	PF00786	0.603
LIG_IRF3_LxIS_1	326	333	PF10401	0.606
LIG_LIR_Apic_2	252	256	PF02991	0.532
LIG_LIR_Apic_2	312	318	PF02991	0.712
LIG_LIR_Nem_3	107	113	PF02991	0.600
LIG_LIR_Nem_3	175	180	PF02991	0.626
LIG_LIR_Nem_3	77	82	PF02991	0.744
LIG_LYPXL_S_1	78	82	PF13949	0.496
LIG_LYPXL_yS_3	79	82	PF13949	0.493
LIG_PCNA_yPIPBox_3	316	326	PF02747	0.546
LIG_PDZ_Class_1	449	454	PF00595	0.617
LIG_Pex14_2	113	117	PF04695	0.495
LIG_SH2_SRC	261	264	PF00017	0.502
LIG_SH2_STAP1	261	265	PF00017	0.505
LIG_SH2_STAP1	416	420	PF00017	0.588
LIG_SH2_STAT5	370	373	PF00017	0.650
LIG_SH3_2	122	127	PF14604	0.522
LIG_SH3_3	108	114	PF00018	0.608
LIG_SH3_3	119	125	PF00018	0.636
LIG_SH3_3	235	241	PF00018	0.759
LIG_SH3_3	403	409	PF00018	0.568
LIG_SUMO_SIM_par_1	148	156	PF11976	0.579
LIG_TRAF2_1	233	236	PF00917	0.649
LIG_TRFH_1	110	114	PF08558	0.483
LIG_WRC_WIRS_1	185	190	PF05994	0.611
LIG_WRC_WIRS_1	322	327	PF05994	0.715
LIG_WW_3	124	128	PF00397	0.528
MOD_CDK_SPK_2	12	17	PF00069	0.544
MOD_CK1_1	15	21	PF00069	0.545
MOD_CK1_1	156	162	PF00069	0.652
MOD_CK1_1	187	193	PF00069	0.711
MOD_CK1_1	264	270	PF00069	0.553
MOD_CK1_1	314	320	PF00069	0.685
MOD_CK1_1	321	327	PF00069	0.637
MOD_CK1_1	377	383	PF00069	0.613
MOD_CK1_1	390	396	PF00069	0.629
MOD_CK1_1	69	75	PF00069	0.627
MOD_CK2_1	15	21	PF00069	0.540
MOD_CK2_1	229	235	PF00069	0.697
MOD_CK2_1	292	298	PF00069	0.695
MOD_CK2_1	347	353	PF00069	0.652
MOD_CK2_1	54	60	PF00069	0.698
MOD_Cter_Amidation	360	363	PF01082	0.664
MOD_GlcNHglycan	118	121	PF01048	0.565
MOD_GlcNHglycan	148	151	PF01048	0.667
MOD_GlcNHglycan	194	197	PF01048	0.677
MOD_GlcNHglycan	213	216	PF01048	0.486
MOD_GlcNHglycan	222	225	PF01048	0.576
MOD_GlcNHglycan	242	245	PF01048	0.648
MOD_GlcNHglycan	278	281	PF01048	0.647
MOD_GlcNHglycan	292	295	PF01048	0.672
MOD_GlcNHglycan	336	339	PF01048	0.650
MOD_GlcNHglycan	364	367	PF01048	0.670
MOD_GlcNHglycan	380	383	PF01048	0.556
MOD_GlcNHglycan	446	449	PF01048	0.598
MOD_GSK3_1	152	159	PF00069	0.631
MOD_GSK3_1	169	176	PF00069	0.538
MOD_GSK3_1	184	191	PF00069	0.630
MOD_GSK3_1	192	199	PF00069	0.715
MOD_GSK3_1	236	243	PF00069	0.627
MOD_GSK3_1	288	295	PF00069	0.623
MOD_GSK3_1	307	314	PF00069	0.604
MOD_GSK3_1	31	38	PF00069	0.621
MOD_GSK3_1	317	324	PF00069	0.528
MOD_GSK3_1	330	337	PF00069	0.653
MOD_GSK3_1	347	354	PF00069	0.559
MOD_GSK3_1	370	377	PF00069	0.684
MOD_GSK3_1	397	404	PF00069	0.576
MOD_GSK3_1	60	67	PF00069	0.658
MOD_GSK3_1	8	15	PF00069	0.664
MOD_LATS_1	396	402	PF00433	0.526
MOD_N-GLC_1	318	323	PF02516	0.545
MOD_NEK2_1	153	158	PF00069	0.524
MOD_NEK2_1	186	191	PF00069	0.659
MOD_NEK2_1	275	280	PF00069	0.684
MOD_NEK2_1	330	335	PF00069	0.615
MOD_NEK2_1	389	394	PF00069	0.540
MOD_NEK2_2	22	27	PF00069	0.531
MOD_PIKK_1	196	202	PF00454	0.617
MOD_PIKK_1	264	270	PF00454	0.553
MOD_PIKK_1	54	60	PF00454	0.654
MOD_PK_1	45	51	PF00069	0.519
MOD_PKA_1	362	368	PF00069	0.664
MOD_PKA_1	397	403	PF00069	0.527
MOD_PKA_1	54	60	PF00069	0.629
MOD_PKA_2	281	287	PF00069	0.679
MOD_PKA_2	362	368	PF00069	0.672
MOD_PKA_2	390	396	PF00069	0.542
MOD_PKA_2	397	403	PF00069	0.598
MOD_PKA_2	444	450	PF00069	0.644
MOD_PKA_2	54	60	PF00069	0.629
MOD_PKB_1	395	403	PF00069	0.524
MOD_Plk_1	261	267	PF00069	0.638
MOD_Plk_1	311	317	PF00069	0.646
MOD_Plk_1	318	324	PF00069	0.578
MOD_Plk_1	60	66	PF00069	0.582
MOD_Plk_2-3	351	357	PF00069	0.640
MOD_Plk_4	189	195	PF00069	0.648
MOD_Plk_4	292	298	PF00069	0.502
MOD_Plk_4	318	324	PF00069	0.643
MOD_Plk_4	351	357	PF00069	0.659
MOD_Plk_4	398	404	PF00069	0.527
MOD_Plk_4	45	51	PF00069	0.560
MOD_Plk_4	60	66	PF00069	0.773
MOD_Plk_4	74	80	PF00069	0.606
MOD_ProDKin_1	12	18	PF00069	0.692
MOD_ProDKin_1	169	175	PF00069	0.651
MOD_ProDKin_1	230	236	PF00069	0.600
MOD_ProDKin_1	314	320	PF00069	0.614
MOD_ProDKin_1	374	380	PF00069	0.567
MOD_ProDKin_1	64	70	PF00069	0.687
TRG_DiLeu_BaEn_1	351	356	PF01217	0.652
TRG_DiLeu_BaEn_4	298	304	PF01217	0.501
TRG_ENDOCYTIC_2	110	113	PF00928	0.606
TRG_ENDOCYTIC_2	79	82	PF00928	0.578
TRG_ER_diArg_1	362	364	PF00400	0.570
TRG_ER_diArg_1	394	397	PF00400	0.638
TRG_Pf-PMV_PEXEL_1	428	432	PF00026	0.602

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X5L4	Leishmania donovani	79%	95%
A4HKI6	Leishmania braziliensis	51%	100%
A4I817	Leishmania infantum	79%	95%
Q4Q581	Leishmania major	78%	100%