Dynein heavy chain 7, axonemal

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2W9_LEIMU

TriTrypDb:

LmxM.31.1910

Length:

734

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2W9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2W9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	132	134	PF00675	0.483
CLV_NRD_NRD_1	31	33	PF00675	0.465
CLV_NRD_NRD_1	36	38	PF00675	0.432
CLV_NRD_NRD_1	94	96	PF00675	0.484
CLV_PCSK_KEX2_1	132	134	PF00082	0.483
CLV_PCSK_KEX2_1	31	33	PF00082	0.465
CLV_PCSK_KEX2_1	315	317	PF00082	0.527
CLV_PCSK_PC1ET2_1	315	317	PF00082	0.445
CLV_PCSK_SKI1_1	209	213	PF00082	0.486
CLV_PCSK_SKI1_1	253	257	PF00082	0.402
CLV_PCSK_SKI1_1	37	41	PF00082	0.458
CLV_PCSK_SKI1_1	62	66	PF00082	0.391
CLV_PCSK_SKI1_1	67	71	PF00082	0.402
DEG_APCC_DBOX_1	265	273	PF00400	0.489
DEG_COP1_1	404	415	PF00400	0.586
DEG_COP1_1	418	427	PF00400	0.560
DEG_COP1_1	440	451	PF00400	0.592
DEG_COP1_1	454	463	PF00400	0.596
DEG_COP1_1	490	499	PF00400	0.595
DEG_COP1_1	514	523	PF00400	0.582
DEG_COP1_1	536	547	PF00400	0.588
DEG_COP1_1	550	559	PF00400	0.557
DEG_COP1_1	574	583	PF00400	0.596
DEG_COP1_1	598	607	PF00400	0.597
DEG_COP1_1	620	631	PF00400	0.576
DEG_COP1_1	634	643	PF00400	0.543
DEG_COP1_1	670	679	PF00400	0.580
DOC_CDC14_PxL_1	285	293	PF14671	0.482
DOC_MAPK_DCC_7	266	274	PF00069	0.405
DOC_MAPK_gen_1	275	285	PF00069	0.517
DOC_MAPK_gen_1	73	80	PF00069	0.473
DOC_MAPK_gen_1	82	89	PF00069	0.412
DOC_MAPK_RevD_3	25	38	PF00069	0.465
DOC_PP1_RVXF_1	207	214	PF00149	0.539
DOC_PP2B_LxvP_1	494	497	PF13499	0.738
DOC_PP2B_LxvP_1	578	581	PF13499	0.605
DOC_PP2B_LxvP_1	674	677	PF13499	0.581
DOC_PP2B_LxvP_1	686	689	PF13499	0.564
DOC_SPAK_OSR1_1	75	79	PF12202	0.393
DOC_USP7_MATH_1	155	159	PF00917	0.385
DOC_USP7_MATH_1	177	181	PF00917	0.369
DOC_USP7_MATH_1	319	323	PF00917	0.503
DOC_USP7_MATH_1	359	363	PF00917	0.584
DOC_USP7_MATH_1	384	388	PF00917	0.653
DOC_WW_Pin1_4	700	705	PF00397	0.586
DOC_WW_Pin1_4	724	729	PF00397	0.735
LIG_14-3-3_CanoR_1	197	205	PF00244	0.440
LIG_14-3-3_CanoR_1	266	270	PF00244	0.490
LIG_14-3-3_CanoR_1	321	327	PF00244	0.546
LIG_BIR_II_1	1	5	PF00653	0.530
LIG_FHA_1	100	106	PF00498	0.470
LIG_FHA_1	21	27	PF00498	0.463
LIG_FHA_2	19	25	PF00498	0.455
LIG_FHA_2	210	216	PF00498	0.435
LIG_FHA_2	306	312	PF00498	0.435
LIG_FHA_2	403	409	PF00498	0.669
LIG_FHA_2	439	445	PF00498	0.651
LIG_FHA_2	45	51	PF00498	0.357
LIG_FHA_2	535	541	PF00498	0.589
LIG_FHA_2	619	625	PF00498	0.572
LIG_FHA_2	720	726	PF00498	0.572
LIG_LIR_Gen_1	10	20	PF02991	0.455
LIG_LIR_Gen_1	210	220	PF02991	0.514
LIG_LIR_Gen_1	234	243	PF02991	0.477
LIG_LIR_Gen_1	322	332	PF02991	0.469
LIG_LIR_Gen_1	47	56	PF02991	0.355
LIG_LIR_Nem_3	10	15	PF02991	0.455
LIG_LIR_Nem_3	180	185	PF02991	0.414
LIG_LIR_Nem_3	188	193	PF02991	0.384
LIG_LIR_Nem_3	210	216	PF02991	0.518
LIG_LIR_Nem_3	234	239	PF02991	0.470
LIG_LIR_Nem_3	268	273	PF02991	0.488
LIG_LIR_Nem_3	279	284	PF02991	0.419
LIG_LIR_Nem_3	322	327	PF02991	0.472
LIG_LIR_Nem_3	47	51	PF02991	0.356
LIG_Pex14_1	232	236	PF04695	0.397
LIG_Pex14_1	326	330	PF04695	0.473
LIG_Pex14_2	281	285	PF04695	0.472
LIG_Rb_LxCxE_1	392	411	PF01857	0.584
LIG_Rb_pABgroove_1	237	245	PF01858	0.397
LIG_REV1ctd_RIR_1	179	185	PF16727	0.453
LIG_SH2_CRK	190	194	PF00017	0.390
LIG_SH2_CRK	236	240	PF00017	0.391
LIG_SH2_CRK	286	290	PF00017	0.409
LIG_SH2_NCK_1	370	374	PF00017	0.572
LIG_SH2_STAP1	12	16	PF00017	0.464
LIG_SH2_STAP1	243	247	PF00017	0.488
LIG_SH2_STAT3	243	246	PF00017	0.482
LIG_SH2_STAT3	81	84	PF00017	0.376
LIG_SH2_STAT5	238	241	PF00017	0.474
LIG_SH3_3	397	403	PF00018	0.598
LIG_SH3_3	409	415	PF00018	0.589
LIG_SH3_3	421	427	PF00018	0.633
LIG_SH3_3	433	439	PF00018	0.559
LIG_SH3_3	445	451	PF00018	0.619
LIG_SH3_3	457	463	PF00018	0.615
LIG_SH3_3	469	475	PF00018	0.569
LIG_SH3_3	481	487	PF00018	0.620
LIG_SH3_3	493	499	PF00018	0.765
LIG_SH3_3	517	523	PF00018	0.681
LIG_SH3_3	529	535	PF00018	0.562
LIG_SH3_3	541	547	PF00018	0.644
LIG_SH3_3	553	559	PF00018	0.768
LIG_SH3_3	565	571	PF00018	0.646
LIG_SH3_3	577	583	PF00018	0.572
LIG_SH3_3	601	607	PF00018	0.617
LIG_SH3_3	613	619	PF00018	0.581
LIG_SH3_3	625	631	PF00018	0.594
LIG_SH3_3	637	643	PF00018	0.706
LIG_SH3_3	649	655	PF00018	0.608
LIG_SH3_3	661	667	PF00018	0.567
LIG_SH3_3	673	679	PF00018	0.557
LIG_TRAF2_1	212	215	PF00917	0.456
LIG_TRAF2_1	39	42	PF00917	0.452
LIG_TRAF2_1	714	717	PF00917	0.573
LIG_WW_3	92	96	PF00397	0.559
MOD_CK1_1	231	237	PF00069	0.481
MOD_CK1_1	322	328	PF00069	0.546
MOD_CK1_1	719	725	PF00069	0.765
MOD_CK2_1	18	24	PF00069	0.424
MOD_CK2_1	200	206	PF00069	0.459
MOD_CK2_1	209	215	PF00069	0.426
MOD_CK2_1	305	311	PF00069	0.434
MOD_CK2_1	4	10	PF00069	0.411
MOD_CK2_1	402	408	PF00069	0.691
MOD_CK2_1	438	444	PF00069	0.630
MOD_CK2_1	534	540	PF00069	0.587
MOD_CK2_1	618	624	PF00069	0.571
MOD_CK2_1	717	723	PF00069	0.567
MOD_GlcNHglycan	202	205	PF01048	0.463
MOD_GlcNHglycan	233	236	PF01048	0.392
MOD_GlcNHglycan	704	707	PF01048	0.574
MOD_GlcNHglycan	719	722	PF01048	0.772
MOD_GSK3_1	155	162	PF00069	0.387
MOD_GSK3_1	715	722	PF00069	0.569
MOD_N-GLC_1	295	300	PF02516	0.431
MOD_NEK2_1	295	300	PF00069	0.505
MOD_NEK2_1	305	310	PF00069	0.432
MOD_NEK2_2	177	182	PF00069	0.372
MOD_PIKK_1	295	301	PF00454	0.510
MOD_PIKK_1	305	311	PF00454	0.442
MOD_PIKK_1	353	359	PF00454	0.586
MOD_PKA_1	82	88	PF00069	0.470
MOD_PKA_2	265	271	PF00069	0.490
MOD_PKA_2	322	328	PF00069	0.521
MOD_Plk_1	170	176	PF00069	0.376
MOD_Plk_1	209	215	PF00069	0.445
MOD_Plk_1	228	234	PF00069	0.362
MOD_Plk_1	348	354	PF00069	0.588
MOD_Plk_1	366	372	PF00069	0.625
MOD_Plk_1	385	391	PF00069	0.617
MOD_Plk_4	170	176	PF00069	0.376
MOD_Plk_4	177	183	PF00069	0.362
MOD_Plk_4	265	271	PF00069	0.498
MOD_Plk_4	385	391	PF00069	0.653
MOD_ProDKin_1	700	706	PF00069	0.586
MOD_ProDKin_1	724	730	PF00069	0.727
MOD_SUMO_rev_2	214	220	PF00179	0.422
MOD_SUMO_rev_2	33	40	PF00179	0.453
TRG_DiLeu_BaEn_3	169	175	PF01217	0.378
TRG_DiLeu_BaLyEn_6	268	273	PF01217	0.405
TRG_ENDOCYTIC_2	12	15	PF00928	0.462
TRG_ENDOCYTIC_2	190	193	PF00928	0.468
TRG_ENDOCYTIC_2	236	239	PF00928	0.390
TRG_ER_diArg_1	132	135	PF00400	0.482
TRG_ER_diArg_1	163	166	PF00400	0.470
TRG_ER_diArg_1	321	324	PF00400	0.521
TRG_ER_diArg_1	73	76	PF00400	0.493
TRG_NES_CRM1_1	241	254	PF08389	0.393
TRG_Pf-PMV_PEXEL_1	121	125	PF00026	0.446
TRG_Pf-PMV_PEXEL_1	132	136	PF00026	0.409
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HKI0	Leishmania braziliensis	63%	100%