CBFD_NFYB_HMF domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2W5_LEIMU

TriTrypDb:

LmxM.31.1875

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2W5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2W5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0005515	protein binding	2	7
GO:0046982	protein heterodimerization activity	4	7
GO:0046983	protein dimerization activity	3	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	117	119	PF00675	0.473
CLV_NRD_NRD_1	54	56	PF00675	0.503
CLV_PCSK_KEX2_1	154	156	PF00082	0.567
CLV_PCSK_KEX2_1	54	56	PF00082	0.540
CLV_PCSK_PC1ET2_1	154	156	PF00082	0.567
CLV_PCSK_SKI1_1	101	105	PF00082	0.576
CLV_PCSK_SKI1_1	118	122	PF00082	0.472
CLV_PCSK_SKI1_1	96	100	PF00082	0.508
DEG_Nend_UBRbox_3	1	3	PF02207	0.641
DOC_USP7_MATH_1	120	124	PF00917	0.608
DOC_USP7_MATH_1	147	151	PF00917	0.474
LIG_14-3-3_CanoR_1	125	129	PF00244	0.450
LIG_FHA_1	102	108	PF00498	0.417
LIG_FHA_1	125	131	PF00498	0.524
LIG_FHA_1	40	46	PF00498	0.506
LIG_SH2_STAT5	109	112	PF00017	0.463
LIG_SUMO_SIM_anti_2	104	109	PF11976	0.422
LIG_UBA3_1	145	154	PF00899	0.485
MOD_CK1_1	123	129	PF00069	0.524
MOD_CK1_1	13	19	PF00069	0.658
MOD_CK1_1	35	41	PF00069	0.614
MOD_CK1_1	60	66	PF00069	0.599
MOD_GlcNHglycan	122	125	PF01048	0.353
MOD_GlcNHglycan	14	18	PF01048	0.650
MOD_GlcNHglycan	35	38	PF01048	0.615
MOD_GlcNHglycan	49	52	PF01048	0.590
MOD_GlcNHglycan	59	62	PF01048	0.615
MOD_GSK3_1	114	121	PF00069	0.447
MOD_GSK3_1	35	42	PF00069	0.485
MOD_GSK3_1	6	13	PF00069	0.650
MOD_NEK2_1	148	153	PF00069	0.577
MOD_NEK2_1	33	38	PF00069	0.474
MOD_NEK2_1	6	11	PF00069	0.595
MOD_PIKK_1	19	25	PF00454	0.514
MOD_PIKK_1	6	12	PF00454	0.622
MOD_PKA_1	118	124	PF00069	0.475
MOD_PKA_2	10	16	PF00069	0.678
MOD_PKA_2	124	130	PF00069	0.455
MOD_Plk_1	26	32	PF00069	0.495
TRG_ER_diArg_1	53	55	PF00400	0.575

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KIL7	Bodo saltans	33%	100%
A0A3S7X5N4	Leishmania donovani	87%	100%
A4HKH6	Leishmania braziliensis	71%	100%
A4I803	Leishmania infantum	87%	100%
Q4Q591	Leishmania major	87%	100%