Bud-site selection protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2V6_LEIMU

TriTrypDb:

LmxM.31.1800

Length:

237

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2V6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2V6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	108	112	PF00656	0.587
CLV_C14_Caspase3-7	113	117	PF00656	0.764
CLV_NRD_NRD_1	142	144	PF00675	0.594
CLV_NRD_NRD_1	146	148	PF00675	0.596
CLV_NRD_NRD_1	160	162	PF00675	0.583
CLV_NRD_NRD_1	19	21	PF00675	0.472
CLV_NRD_NRD_1	38	40	PF00675	0.472
CLV_NRD_NRD_1	45	47	PF00675	0.523
CLV_NRD_NRD_1	66	68	PF00675	0.440
CLV_PCSK_FUR_1	35	39	PF00082	0.403
CLV_PCSK_KEX2_1	141	143	PF00082	0.599
CLV_PCSK_KEX2_1	160	162	PF00082	0.620
CLV_PCSK_KEX2_1	19	21	PF00082	0.472
CLV_PCSK_KEX2_1	31	33	PF00082	0.504
CLV_PCSK_KEX2_1	37	39	PF00082	0.467
CLV_PCSK_KEX2_1	66	68	PF00082	0.440
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.466
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.407
CLV_PCSK_SKI1_1	23	27	PF00082	0.473
DEG_Nend_UBRbox_1	1	4	PF02207	0.556
DEG_SCF_TRCP1_1	116	121	PF00400	0.490
DOC_MAPK_gen_1	26	36	PF00069	0.430
DOC_USP7_MATH_1	12	16	PF00917	0.528
DOC_USP7_MATH_1	232	236	PF00917	0.580
DOC_USP7_MATH_1	99	103	PF00917	0.625
DOC_USP7_UBL2_3	77	81	PF12436	0.566
DOC_WW_Pin1_4	225	230	PF00397	0.555
LIG_14-3-3_CanoR_1	161	167	PF00244	0.579
LIG_14-3-3_CanoR_1	220	229	PF00244	0.625
LIG_BRCT_BRCA1_1	6	10	PF00533	0.557
LIG_FHA_1	231	237	PF00498	0.556
LIG_FHA_1	28	34	PF00498	0.431
LIG_SH2_STAT5	63	66	PF00017	0.451
LIG_SH3_2	229	234	PF14604	0.467
LIG_SH3_3	226	232	PF00018	0.473
LIG_TRAF2_1	49	52	PF00917	0.494
MOD_CDK_SPK_2	225	230	PF00069	0.483
MOD_CK1_1	110	116	PF00069	0.600
MOD_CK1_1	54	60	PF00069	0.451
MOD_CK2_1	118	124	PF00069	0.575
MOD_CK2_1	12	18	PF00069	0.482
MOD_CK2_1	94	100	PF00069	0.632
MOD_GlcNHglycan	116	119	PF01048	0.564
MOD_GlcNHglycan	120	123	PF01048	0.613
MOD_GlcNHglycan	204	207	PF01048	0.691
MOD_GlcNHglycan	210	213	PF01048	0.583
MOD_GlcNHglycan	95	99	PF01048	0.638
MOD_GSK3_1	107	114	PF00069	0.563
MOD_GSK3_1	216	223	PF00069	0.607
MOD_GSK3_1	77	84	PF00069	0.476
MOD_LATS_1	213	219	PF00433	0.632
MOD_N-GLC_1	216	221	PF02516	0.669
MOD_NEK2_1	27	32	PF00069	0.453
MOD_NEK2_1	59	64	PF00069	0.471
MOD_NEK2_2	232	237	PF00069	0.580
MOD_PKA_1	169	175	PF00069	0.521
MOD_PKA_2	202	208	PF00069	0.809
MOD_Plk_1	110	116	PF00069	0.594
MOD_Plk_1	51	57	PF00069	0.464
MOD_Plk_2-3	111	117	PF00069	0.499
MOD_Plk_4	59	65	PF00069	0.447
MOD_ProDKin_1	225	231	PF00069	0.551
TRG_ER_diArg_1	141	143	PF00400	0.659
TRG_ER_diArg_1	159	161	PF00400	0.636
TRG_ER_diArg_1	38	40	PF00400	0.457
TRG_ER_diArg_1	65	67	PF00400	0.441
TRG_NLS_Bipartite_1	19	41	PF00514	0.444
TRG_NLS_MonoExtN_4	35	41	PF00514	0.429

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFN4	Leptomonas seymouri	55%	100%
A0A3Q8IH03	Leishmania donovani	79%	100%
A4HKG7	Leishmania braziliensis	65%	99%
A4I7Z4	Leishmania infantum	78%	97%
Q4Q5A0	Leishmania major	82%	100%