LeishMANIAdb
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ELM2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ELM2 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B2V4_LEIMU
TriTrypDb:
LmxM.31.1780
Length:
179

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2V4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2V4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 56 58 PF00675 0.654
CLV_PCSK_KEX2_1 56 58 PF00082 0.653
CLV_PCSK_PC7_1 52 58 PF00082 0.632
CLV_PCSK_SKI1_1 127 131 PF00082 0.516
CLV_PCSK_SKI1_1 166 170 PF00082 0.626
DOC_MAPK_gen_1 17 27 PF00069 0.674
DOC_PP2B_LxvP_1 25 28 PF13499 0.656
DOC_USP7_MATH_1 161 165 PF00917 0.633
DOC_USP7_MATH_1 171 175 PF00917 0.648
DOC_USP7_UBL2_3 172 176 PF12436 0.722
LIG_14-3-3_CanoR_1 118 126 PF00244 0.599
LIG_deltaCOP1_diTrp_1 121 131 PF00928 0.612
LIG_EVH1_2 28 32 PF00568 0.599
LIG_FHA_2 34 40 PF00498 0.703
LIG_FHA_2 64 70 PF00498 0.428
LIG_LIR_Gen_1 30 40 PF02991 0.616
LIG_LIR_Gen_1 9 18 PF02991 0.620
LIG_LIR_Nem_3 106 112 PF02991 0.592
LIG_LIR_Nem_3 30 35 PF02991 0.618
LIG_LIR_Nem_3 9 15 PF02991 0.639
LIG_REV1ctd_RIR_1 167 177 PF16727 0.609
LIG_SH2_CRK 88 92 PF00017 0.684
LIG_SH2_STAP1 119 123 PF00017 0.525
LIG_SH2_STAT5 100 103 PF00017 0.643
LIG_SH2_STAT5 119 122 PF00017 0.599
LIG_SH2_STAT5 145 148 PF00017 0.562
LIG_SH3_3 155 161 PF00018 0.509
LIG_SUMO_SIM_anti_2 21 26 PF11976 0.672
LIG_SUMO_SIM_anti_2 36 44 PF11976 0.446
LIG_TRAF2_1 36 39 PF00917 0.637
MOD_CK2_1 151 157 PF00069 0.541
MOD_CK2_1 33 39 PF00069 0.702
MOD_GSK3_1 34 41 PF00069 0.550
MOD_LATS_1 92 98 PF00433 0.731
MOD_PKA_2 117 123 PF00069 0.591
MOD_PKA_2 62 68 PF00069 0.696
MOD_Plk_1 38 44 PF00069 0.641
MOD_Plk_1 63 69 PF00069 0.686
MOD_Plk_2-3 78 84 PF00069 0.555
MOD_Plk_4 127 133 PF00069 0.596
MOD_Plk_4 86 92 PF00069 0.686
TRG_ENDOCYTIC_2 109 112 PF00928 0.632
TRG_ENDOCYTIC_2 12 15 PF00928 0.640
TRG_ENDOCYTIC_2 88 91 PF00928 0.643
TRG_ER_diLys_1 175 179 PF00400 0.741
TRG_NLS_MonoExtC_3 171 176 PF00514 0.716

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMN5 Leptomonas seymouri 41% 98%
A0A3S7X5J7 Leishmania donovani 83% 100%
A4HKG5 Leishmania braziliensis 66% 99%
A4I7Z3 Leishmania infantum 84% 100%
Q4Q5A2 Leishmania major 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS