Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2U6_LEIMU

TriTrypDb:

LmxM.31.1700

Length:

838

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2U6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.576
CLV_C14_Caspase3-7	732	736	PF00656	0.594
CLV_NRD_NRD_1	170	172	PF00675	0.631
CLV_NRD_NRD_1	254	256	PF00675	0.632
CLV_NRD_NRD_1	38	40	PF00675	0.609
CLV_NRD_NRD_1	535	537	PF00675	0.597
CLV_NRD_NRD_1	538	540	PF00675	0.609
CLV_NRD_NRD_1	604	606	PF00675	0.630
CLV_NRD_NRD_1	793	795	PF00675	0.585
CLV_PCSK_FUR_1	35	39	PF00082	0.648
CLV_PCSK_KEX2_1	170	172	PF00082	0.631
CLV_PCSK_KEX2_1	37	39	PF00082	0.606
CLV_PCSK_KEX2_1	383	385	PF00082	0.706
CLV_PCSK_KEX2_1	604	606	PF00082	0.630
CLV_PCSK_KEX2_1	727	729	PF00082	0.611
CLV_PCSK_KEX2_1	793	795	PF00082	0.585
CLV_PCSK_PC1ET2_1	383	385	PF00082	0.706
CLV_PCSK_PC1ET2_1	727	729	PF00082	0.556
CLV_PCSK_SKI1_1	404	408	PF00082	0.514
CLV_PCSK_SKI1_1	499	503	PF00082	0.409
CLV_PCSK_SKI1_1	567	571	PF00082	0.523
CLV_PCSK_SKI1_1	728	732	PF00082	0.626
DEG_APCC_DBOX_1	403	411	PF00400	0.499
DEG_APCC_DBOX_1	498	506	PF00400	0.405
DEG_Nend_UBRbox_3	1	3	PF02207	0.590
DEG_SPOP_SBC_1	40	44	PF00917	0.535
DEG_SPOP_SBC_1	82	86	PF00917	0.527
DOC_CKS1_1	621	626	PF01111	0.704
DOC_CKS1_1	638	643	PF01111	0.498
DOC_CKS1_1	765	770	PF01111	0.573
DOC_CYCLIN_RxL_1	409	420	PF00134	0.478
DOC_CYCLIN_yCln2_LP_2	235	241	PF00134	0.550
DOC_MAPK_gen_1	6	14	PF00069	0.509
DOC_PP1_RVXF_1	243	249	PF00149	0.612
DOC_PP2B_LxvP_1	720	723	PF13499	0.547
DOC_PP4_FxxP_1	613	616	PF00568	0.599
DOC_USP7_MATH_1	121	125	PF00917	0.638
DOC_USP7_MATH_1	269	273	PF00917	0.543
DOC_USP7_MATH_1	344	348	PF00917	0.626
DOC_USP7_MATH_1	40	44	PF00917	0.571
DOC_USP7_MATH_1	493	497	PF00917	0.464
DOC_USP7_MATH_1	530	534	PF00917	0.584
DOC_USP7_MATH_1	538	542	PF00917	0.572
DOC_USP7_MATH_1	558	562	PF00917	0.603
DOC_USP7_MATH_1	72	76	PF00917	0.632
DOC_USP7_MATH_1	77	81	PF00917	0.623
DOC_USP7_MATH_1	785	789	PF00917	0.582
DOC_USP7_MATH_1	94	98	PF00917	0.569
DOC_WW_Pin1_4	129	134	PF00397	0.627
DOC_WW_Pin1_4	229	234	PF00397	0.602
DOC_WW_Pin1_4	240	245	PF00397	0.536
DOC_WW_Pin1_4	261	266	PF00397	0.624
DOC_WW_Pin1_4	29	34	PF00397	0.563
DOC_WW_Pin1_4	290	295	PF00397	0.583
DOC_WW_Pin1_4	327	332	PF00397	0.586
DOC_WW_Pin1_4	340	345	PF00397	0.567
DOC_WW_Pin1_4	363	368	PF00397	0.549
DOC_WW_Pin1_4	506	511	PF00397	0.388
DOC_WW_Pin1_4	620	625	PF00397	0.706
DOC_WW_Pin1_4	637	642	PF00397	0.500
DOC_WW_Pin1_4	674	679	PF00397	0.505
DOC_WW_Pin1_4	708	713	PF00397	0.493
DOC_WW_Pin1_4	749	754	PF00397	0.600
DOC_WW_Pin1_4	764	769	PF00397	0.583
DOC_WW_Pin1_4	783	788	PF00397	0.563
DOC_WW_Pin1_4	804	809	PF00397	0.625
LIG_14-3-3_CanoR_1	107	112	PF00244	0.583
LIG_14-3-3_CanoR_1	170	180	PF00244	0.631
LIG_14-3-3_CanoR_1	297	307	PF00244	0.629
LIG_14-3-3_CanoR_1	433	438	PF00244	0.394
LIG_14-3-3_CanoR_1	446	450	PF00244	0.463
LIG_14-3-3_CanoR_1	62	71	PF00244	0.684
LIG_14-3-3_CanoR_1	684	692	PF00244	0.480
LIG_14-3-3_CanoR_1	793	797	PF00244	0.581
LIG_14-3-3_CanoR_1	817	822	PF00244	0.626
LIG_Actin_WH2_2	660	677	PF00022	0.469
LIG_BIR_III_2	130	134	PF00653	0.573
LIG_CtBP_PxDLS_1	250	256	PF00389	0.516
LIG_deltaCOP1_diTrp_1	424	431	PF00928	0.489
LIG_Dynein_DLC8_1	310	316	PF01221	0.636
LIG_EH1_1	774	782	PF00400	0.581
LIG_FHA_1	121	127	PF00498	0.636
LIG_FHA_1	136	142	PF00498	0.454
LIG_FHA_1	16	22	PF00498	0.456
LIG_FHA_1	215	221	PF00498	0.633
LIG_FHA_1	223	229	PF00498	0.577
LIG_FHA_1	230	236	PF00498	0.487
LIG_FHA_1	373	379	PF00498	0.522
LIG_FHA_1	616	622	PF00498	0.590
LIG_FHA_1	715	721	PF00498	0.588
LIG_FHA_1	84	90	PF00498	0.529
LIG_FHA_2	312	318	PF00498	0.635
LIG_FHA_2	448	454	PF00498	0.515
LIG_FHA_2	507	513	PF00498	0.518
LIG_FHA_2	568	574	PF00498	0.588
LIG_FHA_2	85	91	PF00498	0.644
LIG_Integrin_isoDGR_2	644	646	PF01839	0.513
LIG_LIR_Apic_2	611	616	PF02991	0.603
LIG_LIR_Gen_1	428	438	PF02991	0.428
LIG_LIR_Gen_1	550	558	PF02991	0.548
LIG_LIR_Gen_1	670	679	PF02991	0.498
LIG_LIR_Gen_1	695	703	PF02991	0.433
LIG_LIR_Nem_3	362	368	PF02991	0.604
LIG_LIR_Nem_3	428	434	PF02991	0.433
LIG_LIR_Nem_3	550	555	PF02991	0.547
LIG_LIR_Nem_3	670	674	PF02991	0.480
LIG_LIR_Nem_3	677	683	PF02991	0.440
LIG_LIR_Nem_3	695	699	PF02991	0.446
LIG_LIR_Nem_3	800	805	PF02991	0.625
LIG_MAD2	779	787	PF02301	0.542
LIG_NRBOX	663	669	PF00104	0.464
LIG_PCNA_yPIPBox_3	658	668	PF02747	0.468
LIG_Pex14_1	431	435	PF04695	0.419
LIG_Pex14_2	515	519	PF04695	0.529
LIG_Pex14_2	692	696	PF04695	0.444
LIG_SH2_CRK	435	439	PF00017	0.464
LIG_SH2_CRK	802	806	PF00017	0.632
LIG_SH2_NCK_1	806	810	PF00017	0.511
LIG_SH2_SRC	526	529	PF00017	0.540
LIG_SH2_STAT3	405	408	PF00017	0.447
LIG_SH2_STAT5	247	250	PF00017	0.503
LIG_SH2_STAT5	405	408	PF00017	0.522
LIG_SH2_STAT5	435	438	PF00017	0.418
LIG_SH2_STAT5	526	529	PF00017	0.540
LIG_SH3_1	288	294	PF00018	0.637
LIG_SH3_3	238	244	PF00018	0.502
LIG_SH3_3	288	294	PF00018	0.637
LIG_SH3_3	397	403	PF00018	0.518
LIG_SH3_3	492	498	PF00018	0.527
LIG_SH3_3	524	530	PF00018	0.540
LIG_SH3_3	552	558	PF00018	0.609
LIG_SH3_3	762	768	PF00018	0.594
LIG_SUMO_SIM_anti_2	138	143	PF11976	0.478
LIG_SUMO_SIM_anti_2	15	21	PF11976	0.475
LIG_SUMO_SIM_anti_2	23	28	PF11976	0.492
LIG_SUMO_SIM_par_1	17	23	PF11976	0.457
LIG_SUMO_SIM_par_1	237	243	PF11976	0.494
LIG_SUMO_SIM_par_1	271	278	PF11976	0.525
LIG_SUMO_SIM_par_1	439	448	PF11976	0.438
LIG_SUMO_SIM_par_1	716	721	PF11976	0.589
LIG_TRAF2_1	422	425	PF00917	0.506
LIG_UBA3_1	590	599	PF00899	0.485
LIG_UBA3_1	718	727	PF00899	0.544
LIG_Vh1_VBS_1	12	30	PF01044	0.532
LIG_WRC_WIRS_1	668	673	PF05994	0.462
MOD_CDK_SPK_2	229	234	PF00069	0.542
MOD_CDK_SPK_2	240	245	PF00069	0.540
MOD_CDK_SPxK_1	29	35	PF00069	0.613
MOD_CDK_SPxK_1	329	335	PF00069	0.574
MOD_CDK_SPxK_1	764	770	PF00069	0.579
MOD_CDK_SPxxK_3	129	136	PF00069	0.628
MOD_CDK_SPxxK_3	290	297	PF00069	0.642
MOD_CDK_SPxxK_3	506	513	PF00069	0.405
MOD_CK1_1	129	135	PF00069	0.627
MOD_CK1_1	15	21	PF00069	0.433
MOD_CK1_1	292	298	PF00069	0.590
MOD_CK1_1	42	48	PF00069	0.573
MOD_CK1_1	448	454	PF00069	0.540
MOD_CK1_1	560	566	PF00069	0.567
MOD_CK1_1	63	69	PF00069	0.606
MOD_CK1_1	711	717	PF00069	0.564
MOD_CK1_1	740	746	PF00069	0.645
MOD_CK1_1	749	755	PF00069	0.741
MOD_CK1_1	788	794	PF00069	0.595
MOD_CK2_1	121	127	PF00069	0.636
MOD_CK2_1	311	317	PF00069	0.590
MOD_CK2_1	344	350	PF00069	0.501
MOD_CK2_1	542	548	PF00069	0.609
MOD_CK2_1	567	573	PF00069	0.632
MOD_CK2_1	644	650	PF00069	0.507
MOD_CK2_1	698	704	PF00069	0.478
MOD_DYRK1A_RPxSP_1	764	768	PF00069	0.633
MOD_GlcNHglycan	152	155	PF01048	0.598
MOD_GlcNHglycan	175	178	PF01048	0.636
MOD_GlcNHglycan	183	186	PF01048	0.563
MOD_GlcNHglycan	194	197	PF01048	0.496
MOD_GlcNHglycan	317	321	PF01048	0.640
MOD_GlcNHglycan	52	55	PF01048	0.629
MOD_GlcNHglycan	540	543	PF01048	0.780
MOD_GlcNHglycan	646	649	PF01048	0.552
MOD_GlcNHglycan	650	653	PF01048	0.551
MOD_GlcNHglycan	700	703	PF01048	0.421
MOD_GlcNHglycan	713	716	PF01048	0.521
MOD_GlcNHglycan	748	751	PF01048	0.633
MOD_GlcNHglycan	787	790	PF01048	0.623
MOD_GlcNHglycan	79	82	PF01048	0.641
MOD_GlcNHglycan	821	824	PF01048	0.576
MOD_GSK3_1	121	128	PF00069	0.637
MOD_GSK3_1	194	201	PF00069	0.576
MOD_GSK3_1	210	217	PF00069	0.593
MOD_GSK3_1	269	276	PF00069	0.574
MOD_GSK3_1	292	299	PF00069	0.607
MOD_GSK3_1	311	318	PF00069	0.690
MOD_GSK3_1	340	347	PF00069	0.570
MOD_GSK3_1	42	49	PF00069	0.630
MOD_GSK3_1	444	451	PF00069	0.615
MOD_GSK3_1	538	545	PF00069	0.618
MOD_GSK3_1	556	563	PF00069	0.456
MOD_GSK3_1	60	67	PF00069	0.538
MOD_GSK3_1	644	651	PF00069	0.770
MOD_GSK3_1	663	670	PF00069	0.422
MOD_GSK3_1	736	743	PF00069	0.589
MOD_GSK3_1	748	755	PF00069	0.600
MOD_GSK3_1	77	84	PF00069	0.596
MOD_GSK3_1	779	786	PF00069	0.550
MOD_GSK3_1	788	795	PF00069	0.587
MOD_GSK3_1	94	101	PF00069	0.753
MOD_LATS_1	597	603	PF00433	0.540
MOD_N-GLC_1	350	355	PF02516	0.570
MOD_N-GLC_1	743	748	PF02516	0.678
MOD_NEK2_1	20	25	PF00069	0.471
MOD_NEK2_1	251	256	PF00069	0.519
MOD_NEK2_1	444	449	PF00069	0.380
MOD_NEK2_1	505	510	PF00069	0.497
MOD_NEK2_1	531	536	PF00069	0.488
MOD_NEK2_1	562	567	PF00069	0.599
MOD_NEK2_1	667	672	PF00069	0.426
MOD_PIKK_1	201	207	PF00454	0.581
MOD_PIKK_1	298	304	PF00454	0.595
MOD_PIKK_1	311	317	PF00454	0.725
MOD_PIKK_1	318	324	PF00454	0.534
MOD_PIKK_1	386	392	PF00454	0.633
MOD_PIKK_1	608	614	PF00454	0.599
MOD_PIKK_1	98	104	PF00454	0.645
MOD_PK_1	273	279	PF00069	0.521
MOD_PK_1	396	402	PF00069	0.570
MOD_PKA_1	599	605	PF00069	0.551
MOD_PKA_2	296	302	PF00069	0.637
MOD_PKA_2	311	317	PF00069	0.523
MOD_PKA_2	445	451	PF00069	0.492
MOD_PKA_2	538	544	PF00069	0.569
MOD_PKA_2	63	69	PF00069	0.606
MOD_PKA_2	683	689	PF00069	0.483
MOD_PKA_2	792	798	PF00069	0.629
MOD_PKB_1	37	45	PF00069	0.650
MOD_PKB_1	62	70	PF00069	0.685
MOD_PKB_1	817	825	PF00069	0.630
MOD_Plk_1	478	484	PF00069	0.548
MOD_Plk_1	574	580	PF00069	0.569
MOD_Plk_1	737	743	PF00069	0.564
MOD_Plk_2-3	574	580	PF00069	0.603
MOD_Plk_4	15	21	PF00069	0.463
MOD_Plk_4	396	402	PF00069	0.570
MOD_Plk_4	433	439	PF00069	0.467
MOD_Plk_4	663	669	PF00069	0.476
MOD_Plk_4	7	13	PF00069	0.497
MOD_Plk_4	714	720	PF00069	0.526
MOD_ProDKin_1	129	135	PF00069	0.627
MOD_ProDKin_1	229	235	PF00069	0.601
MOD_ProDKin_1	240	246	PF00069	0.536
MOD_ProDKin_1	261	267	PF00069	0.620
MOD_ProDKin_1	29	35	PF00069	0.569
MOD_ProDKin_1	290	296	PF00069	0.585
MOD_ProDKin_1	327	333	PF00069	0.583
MOD_ProDKin_1	340	346	PF00069	0.566
MOD_ProDKin_1	363	369	PF00069	0.551
MOD_ProDKin_1	506	512	PF00069	0.397
MOD_ProDKin_1	620	626	PF00069	0.706
MOD_ProDKin_1	637	643	PF00069	0.498
MOD_ProDKin_1	674	680	PF00069	0.498
MOD_ProDKin_1	708	714	PF00069	0.492
MOD_ProDKin_1	749	755	PF00069	0.600
MOD_ProDKin_1	764	770	PF00069	0.579
MOD_ProDKin_1	783	789	PF00069	0.564
MOD_ProDKin_1	804	810	PF00069	0.625
MOD_SUMO_for_1	325	328	PF00179	0.534
MOD_SUMO_rev_2	512	522	PF00179	0.487
TRG_DiLeu_BaEn_1	500	505	PF01217	0.426
TRG_DiLeu_BaEn_2	8	14	PF01217	0.491
TRG_DiLeu_BaEn_3	573	579	PF01217	0.507
TRG_DiLeu_BaLyEn_6	412	417	PF01217	0.490
TRG_DiLeu_BaLyEn_6	586	591	PF01217	0.492
TRG_DiLeu_BaLyEn_6	702	707	PF01217	0.453
TRG_ENDOCYTIC_2	435	438	PF00928	0.418
TRG_ENDOCYTIC_2	802	805	PF00928	0.631
TRG_ER_diArg_1	169	171	PF00400	0.631
TRG_ER_diArg_1	35	38	PF00400	0.703
TRG_ER_diArg_1	604	606	PF00400	0.578
TRG_ER_diArg_1	672	675	PF00400	0.482
TRG_ER_diArg_1	68	71	PF00400	0.814
TRG_NLS_MonoExtC_3	535	540	PF00514	0.523
TRG_Pf-PMV_PEXEL_1	415	419	PF00026	0.448
TRG_Pf-PMV_PEXEL_1	567	571	PF00026	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I482	Leptomonas seymouri	39%	100%
A4I7Y5	Leishmania infantum	85%	100%