Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2T9_LEIMU

TriTrypDb:

LmxM.31.1635

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2T9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2T9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	111	113	PF00082	0.700
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.700
CLV_PCSK_SKI1_1	98	102	PF00082	0.657
DEG_APCC_DBOX_1	129	137	PF00400	0.772
DEG_SCF_FBW7_1	221	227	PF00400	0.563
DEG_SPOP_SBC_1	187	191	PF00917	0.626
DEG_SPOP_SBC_1	45	49	PF00917	0.577
DOC_CKS1_1	176	181	PF01111	0.608
DOC_CKS1_1	221	226	PF01111	0.663
DOC_PP4_FxxP_1	200	203	PF00568	0.755
DOC_USP7_MATH_1	153	157	PF00917	0.757
DOC_USP7_MATH_1	186	190	PF00917	0.762
DOC_USP7_MATH_1	45	49	PF00917	0.721
DOC_USP7_MATH_2	179	185	PF00917	0.740
DOC_USP7_UBL2_3	234	238	PF12436	0.698
DOC_USP7_UBL2_3	245	249	PF12436	0.369
DOC_WW_Pin1_4	122	127	PF00397	0.647
DOC_WW_Pin1_4	158	163	PF00397	0.744
DOC_WW_Pin1_4	175	180	PF00397	0.758
DOC_WW_Pin1_4	188	193	PF00397	0.573
DOC_WW_Pin1_4	195	200	PF00397	0.634
DOC_WW_Pin1_4	205	210	PF00397	0.562
DOC_WW_Pin1_4	220	225	PF00397	0.538
DOC_WW_Pin1_4	37	42	PF00397	0.755
DOC_WW_Pin1_4	52	57	PF00397	0.585
DOC_WW_Pin1_4	65	70	PF00397	0.778
LIG_14-3-3_CanoR_1	112	118	PF00244	0.655
LIG_14-3-3_CanoR_1	130	134	PF00244	0.760
LIG_14-3-3_CanoR_1	50	56	PF00244	0.519
LIG_14-3-3_CanoR_1	67	76	PF00244	0.701
LIG_Actin_WH2_2	95	113	PF00022	0.746
LIG_BIR_II_1	1	5	PF00653	0.641
LIG_BIR_III_4	116	120	PF00653	0.506
LIG_BRCT_BRCA1_1	239	243	PF00533	0.518
LIG_BRCT_BRCA1_2	239	245	PF00533	0.517
LIG_FHA_1	167	173	PF00498	0.769
LIG_FHA_2	176	182	PF00498	0.759
LIG_FHA_2	188	194	PF00498	0.556
LIG_LIR_Apic_2	198	203	PF02991	0.756
LIG_LIR_Gen_1	240	247	PF02991	0.514
LIG_MLH1_MIPbox_1	239	243	PF16413	0.518
LIG_NRP_CendR_1	249	250	PF00754	0.639
LIG_PCNA_PIPBox_1	236	245	PF02747	0.523
LIG_PCNA_yPIPBox_3	234	243	PF02747	0.542
LIG_REV1ctd_RIR_1	240	249	PF16727	0.521
LIG_SH3_3	15	21	PF00018	0.718
LIG_SH3_3	218	224	PF00018	0.722
LIG_SH3_3	73	79	PF00018	0.754
LIG_SUMO_SIM_anti_2	97	104	PF11976	0.734
LIG_TRAF2_1	215	218	PF00917	0.644
MOD_CDC14_SPxK_1	161	164	PF00782	0.494
MOD_CDK_SPxK_1	158	164	PF00069	0.498
MOD_CDK_SPxxK_3	175	182	PF00069	0.760
MOD_CDK_SPxxK_3	188	195	PF00069	0.611
MOD_CDK_SPxxK_3	199	206	PF00069	0.567
MOD_CK1_1	156	162	PF00069	0.616
MOD_CK1_1	168	174	PF00069	0.602
MOD_CK1_1	227	233	PF00069	0.715
MOD_CK1_1	48	54	PF00069	0.762
MOD_CK1_1	68	74	PF00069	0.766
MOD_CK2_1	175	181	PF00069	0.706
MOD_CK2_1	187	193	PF00069	0.668
MOD_CK2_1	211	217	PF00069	0.768
MOD_CK2_1	29	35	PF00069	0.752
MOD_GlcNHglycan	104	108	PF01048	0.650
MOD_GlcNHglycan	151	154	PF01048	0.728
MOD_GlcNHglycan	211	214	PF01048	0.731
MOD_GlcNHglycan	70	73	PF01048	0.664
MOD_GSK3_1	138	145	PF00069	0.663
MOD_GSK3_1	149	156	PF00069	0.633
MOD_GSK3_1	171	178	PF00069	0.624
MOD_GSK3_1	195	202	PF00069	0.754
MOD_GSK3_1	205	212	PF00069	0.708
MOD_GSK3_1	220	227	PF00069	0.560
MOD_GSK3_1	237	244	PF00069	0.445
MOD_GSK3_1	37	44	PF00069	0.555
MOD_GSK3_1	48	55	PF00069	0.788
MOD_NEK2_1	11	16	PF00069	0.701
MOD_NEK2_1	211	216	PF00069	0.790
MOD_NEK2_1	94	99	PF00069	0.656
MOD_PIKK_1	143	149	PF00454	0.656
MOD_PIKK_1	227	233	PF00454	0.701
MOD_PKA_1	111	117	PF00069	0.496
MOD_PKA_2	111	117	PF00069	0.652
MOD_PKA_2	129	135	PF00069	0.755
MOD_PKA_2	181	187	PF00069	0.745
MOD_PKA_2	36	42	PF00069	0.483
MOD_Plk_1	217	223	PF00069	0.780
MOD_Plk_2-3	217	223	PF00069	0.518
MOD_Plk_4	171	177	PF00069	0.681
MOD_ProDKin_1	122	128	PF00069	0.647
MOD_ProDKin_1	158	164	PF00069	0.745
MOD_ProDKin_1	175	181	PF00069	0.750
MOD_ProDKin_1	188	194	PF00069	0.570
MOD_ProDKin_1	195	201	PF00069	0.634
MOD_ProDKin_1	205	211	PF00069	0.564
MOD_ProDKin_1	220	226	PF00069	0.538
MOD_ProDKin_1	37	43	PF00069	0.757
MOD_ProDKin_1	52	58	PF00069	0.588
MOD_ProDKin_1	65	71	PF00069	0.776

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P9J6	Leptomonas seymouri	34%	99%
A0A3S5IRE5	Trypanosoma rangeli	31%	100%
A0A3S7X5K9	Leishmania donovani	83%	100%
A4I7X8	Leishmania infantum	82%	100%
Q4Q5B7	Leishmania major	82%	100%