Phosphoglycan_beta_1_-3_galactosyltransferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2S8_LEIMU

TriTrypDb:

LmxM.31.1520

Length:

524

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

E9B2S8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2S8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	125	129	PF00656	0.357
CLV_C14_Caspase3-7	250	254	PF00656	0.441
CLV_C14_Caspase3-7	358	362	PF00656	0.441
CLV_C14_Caspase3-7	465	469	PF00656	0.440
CLV_NRD_NRD_1	10	12	PF00675	0.493
CLV_NRD_NRD_1	142	144	PF00675	0.680
CLV_NRD_NRD_1	193	195	PF00675	0.689
CLV_NRD_NRD_1	380	382	PF00675	0.630
CLV_PCSK_FUR_1	191	195	PF00082	0.663
CLV_PCSK_FUR_1	8	12	PF00082	0.503
CLV_PCSK_KEX2_1	10	12	PF00082	0.493
CLV_PCSK_KEX2_1	193	195	PF00082	0.689
CLV_PCSK_KEX2_1	210	212	PF00082	0.691
CLV_PCSK_KEX2_1	382	384	PF00082	0.628
CLV_PCSK_KEX2_1	47	49	PF00082	0.730
CLV_PCSK_PC1ET2_1	210	212	PF00082	0.658
CLV_PCSK_PC1ET2_1	382	384	PF00082	0.550
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.705
CLV_PCSK_SKI1_1	108	112	PF00082	0.615
CLV_PCSK_SKI1_1	194	198	PF00082	0.660
CLV_PCSK_SKI1_1	255	259	PF00082	0.699
CLV_PCSK_SKI1_1	340	344	PF00082	0.603
CLV_PCSK_SKI1_1	377	381	PF00082	0.658
CLV_PCSK_SKI1_1	433	437	PF00082	0.524
CLV_PCSK_SKI1_1	48	52	PF00082	0.705
CLV_PCSK_SKI1_1	500	504	PF00082	0.684
CLV_Separin_Metazoa	372	376	PF03568	0.399
DEG_Nend_UBRbox_2	1	3	PF02207	0.649
DEG_SPOP_SBC_1	453	457	PF00917	0.443
DOC_CDC14_PxL_1	351	359	PF14671	0.407
DOC_CYCLIN_RxL_1	374	384	PF00134	0.457
DOC_CYCLIN_RxL_1	430	439	PF00134	0.307
DOC_MAPK_gen_1	140	149	PF00069	0.414
DOC_MAPK_gen_1	442	453	PF00069	0.447
DOC_MAPK_gen_1	93	101	PF00069	0.316
DOC_MAPK_MEF2A_6	140	149	PF00069	0.333
DOC_MAPK_MEF2A_6	20	27	PF00069	0.223
DOC_PP2B_LxvP_1	292	295	PF13499	0.439
DOC_PP2B_LxvP_1	41	44	PF13499	0.514
DOC_PP4_FxxP_1	419	422	PF00568	0.280
DOC_USP7_MATH_1	129	133	PF00917	0.438
DOC_USP7_MATH_1	295	299	PF00917	0.367
DOC_USP7_MATH_1	368	372	PF00917	0.416
DOC_USP7_MATH_1	42	46	PF00917	0.468
DOC_USP7_MATH_1	422	426	PF00917	0.421
DOC_USP7_MATH_1	452	456	PF00917	0.444
DOC_USP7_MATH_1	470	474	PF00917	0.443
DOC_USP7_MATH_1	486	490	PF00917	0.536
DOC_USP7_MATH_1	67	71	PF00917	0.384
DOC_WW_Pin1_4	225	230	PF00397	0.383
DOC_WW_Pin1_4	270	275	PF00397	0.457
DOC_WW_Pin1_4	283	288	PF00397	0.417
DOC_WW_Pin1_4	395	400	PF00397	0.400
DOC_WW_Pin1_4	406	411	PF00397	0.439
DOC_WW_Pin1_4	482	487	PF00397	0.503
LIG_14-3-3_CanoR_1	296	300	PF00244	0.454
LIG_14-3-3_CanoR_1	327	337	PF00244	0.397
LIG_14-3-3_CanoR_1	405	410	PF00244	0.323
LIG_14-3-3_CanoR_1	454	460	PF00244	0.489
LIG_14-3-3_CanoR_1	517	523	PF00244	0.468
LIG_14-3-3_CanoR_1	60	66	PF00244	0.399
LIG_Actin_WH2_2	311	329	PF00022	0.416
LIG_BIR_III_4	263	267	PF00653	0.444
LIG_BRCT_BRCA1_1	331	335	PF00533	0.379
LIG_Clathr_ClatBox_1	435	439	PF01394	0.355
LIG_CSL_BTD_1	284	287	PF09270	0.427
LIG_FHA_1	122	128	PF00498	0.467
LIG_FHA_1	156	162	PF00498	0.455
LIG_FHA_1	165	171	PF00498	0.373
LIG_FHA_1	455	461	PF00498	0.535
LIG_FHA_2	248	254	PF00498	0.441
LIG_FHA_2	329	335	PF00498	0.420
LIG_FHA_2	463	469	PF00498	0.438
LIG_LIR_Gen_1	16	26	PF02991	0.512
LIG_LIR_Gen_1	168	179	PF02991	0.458
LIG_LIR_Gen_1	302	312	PF02991	0.465
LIG_LIR_Gen_1	350	357	PF02991	0.388
LIG_LIR_Gen_1	413	423	PF02991	0.291
LIG_LIR_Gen_1	516	523	PF02991	0.512
LIG_LIR_Nem_3	16	21	PF02991	0.636
LIG_LIR_Nem_3	168	174	PF02991	0.453
LIG_LIR_Nem_3	302	307	PF02991	0.434
LIG_LIR_Nem_3	350	354	PF02991	0.376
LIG_LIR_Nem_3	389	395	PF02991	0.392
LIG_LIR_Nem_3	413	419	PF02991	0.294
LIG_LIR_Nem_3	516	521	PF02991	0.514
LIG_MYND_1	86	90	PF01753	0.471
LIG_NRBOX	338	344	PF00104	0.402
LIG_PALB2_WD40_1	424	432	PF16756	0.327
LIG_PCNA_yPIPBox_3	340	352	PF02747	0.396
LIG_Pex14_1	103	107	PF04695	0.447
LIG_Pex14_1	391	395	PF04695	0.393
LIG_SH2_CRK	107	111	PF00017	0.446
LIG_SH2_CRK	18	22	PF00017	0.492
LIG_SH2_CRK	304	308	PF00017	0.433
LIG_SH2_CRK	316	320	PF00017	0.350
LIG_SH2_NCK_1	304	308	PF00017	0.367
LIG_SH2_STAP1	18	22	PF00017	0.512
LIG_SH2_STAP1	214	218	PF00017	0.470
LIG_SH2_STAP1	388	392	PF00017	0.376
LIG_SH2_STAT5	156	159	PF00017	0.434
LIG_SH2_STAT5	169	172	PF00017	0.347
LIG_SH2_STAT5	291	294	PF00017	0.408
LIG_SH2_STAT5	304	307	PF00017	0.404
LIG_SH2_STAT5	87	90	PF00017	0.462
LIG_SH3_3	184	190	PF00018	0.525
LIG_SH3_3	370	376	PF00018	0.406
LIG_Sin3_3	19	26	PF02671	0.468
LIG_SUMO_SIM_par_1	145	153	PF11976	0.439
LIG_SUMO_SIM_par_1	232	238	PF11976	0.398
LIG_TRFH_1	395	399	PF08558	0.299
LIG_TYR_ITIM	105	110	PF00017	0.404
LIG_TYR_ITIM	314	319	PF00017	0.396
LIG_UBA3_1	420	426	PF00899	0.376
LIG_WRC_WIRS_1	348	353	PF05994	0.382
MOD_CDK_SPxxK_3	270	277	PF00069	0.423
MOD_CK1_1	123	129	PF00069	0.393
MOD_CK1_1	136	142	PF00069	0.478
MOD_CK1_1	302	308	PF00069	0.424
MOD_CK1_1	477	483	PF00069	0.532
MOD_CK1_1	485	491	PF00069	0.462
MOD_CK2_1	328	334	PF00069	0.435
MOD_CK2_1	510	516	PF00069	0.503
MOD_GlcNHglycan	175	178	PF01048	0.752
MOD_GlcNHglycan	331	334	PF01048	0.640
MOD_GlcNHglycan	44	47	PF01048	0.677
MOD_GlcNHglycan	475	479	PF01048	0.720
MOD_GlcNHglycan	481	484	PF01048	0.669
MOD_GSK3_1	123	130	PF00069	0.482
MOD_GSK3_1	165	172	PF00069	0.465
MOD_GSK3_1	201	208	PF00069	0.436
MOD_GSK3_1	295	302	PF00069	0.439
MOD_GSK3_1	459	466	PF00069	0.459
MOD_GSK3_1	470	477	PF00069	0.514
MOD_GSK3_1	478	485	PF00069	0.530
MOD_GSK3_1	59	66	PF00069	0.542
MOD_N-GLC_1	299	304	PF02516	0.670
MOD_NEK2_1	106	111	PF00069	0.407
MOD_NEK2_1	121	126	PF00069	0.344
MOD_NEK2_1	299	304	PF00069	0.494
MOD_NEK2_1	6	11	PF00069	0.724
MOD_NEK2_1	63	68	PF00069	0.557
MOD_PIKK_1	235	241	PF00454	0.513
MOD_PIKK_1	247	253	PF00454	0.468
MOD_PKA_2	295	301	PF00069	0.441
MOD_PKA_2	329	335	PF00069	0.355
MOD_PKA_2	453	459	PF00069	0.503
MOD_PKA_2	516	522	PF00069	0.502
MOD_PKA_2	59	65	PF00069	0.401
MOD_Plk_1	299	305	PF00069	0.489
MOD_Plk_4	165	171	PF00069	0.438
MOD_Plk_4	299	305	PF00069	0.441
MOD_Plk_4	347	353	PF00069	0.389
MOD_ProDKin_1	225	231	PF00069	0.388
MOD_ProDKin_1	270	276	PF00069	0.453
MOD_ProDKin_1	283	289	PF00069	0.411
MOD_ProDKin_1	395	401	PF00069	0.399
MOD_ProDKin_1	406	412	PF00069	0.436
MOD_ProDKin_1	482	488	PF00069	0.501
MOD_SUMO_for_1	13	16	PF00179	0.671
MOD_SUMO_for_1	220	223	PF00179	0.343
MOD_SUMO_for_1	276	279	PF00179	0.401
TRG_ENDOCYTIC_2	107	110	PF00928	0.466
TRG_ENDOCYTIC_2	18	21	PF00928	0.672
TRG_ENDOCYTIC_2	291	294	PF00928	0.408
TRG_ENDOCYTIC_2	304	307	PF00928	0.404
TRG_ENDOCYTIC_2	316	319	PF00928	0.302
TRG_ENDOCYTIC_2	416	419	PF00928	0.306
TRG_ER_diArg_1	192	194	PF00400	0.490
TRG_ER_diArg_1	374	377	PF00400	0.517
TRG_ER_diArg_1	380	383	PF00400	0.418
TRG_ER_diArg_1	7	10	PF00400	0.714
TRG_Pf-PMV_PEXEL_1	108	113	PF00026	0.613
TRG_Pf-PMV_PEXEL_1	340	345	PF00026	0.601
TRG_Pf-PMV_PEXEL_1	383	387	PF00026	0.551

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X5J8	Leishmania donovani	79%	100%
A4HKE0	Leishmania braziliensis	52%	100%
A4I7W8	Leishmania infantum	78%	89%
Q4Q5C9	Leishmania major	77%	100%