LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B2R9_LEIMU
TriTrypDb:
LmxM.31.1440
Length:
147

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2R9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2R9

PDB structure(s): 7aih_BC , 7ane_BC

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 51 53 PF00675 0.552
CLV_PCSK_KEX2_1 51 53 PF00082 0.527
CLV_PCSK_KEX2_1 7 9 PF00082 0.475
CLV_PCSK_PC1ET2_1 7 9 PF00082 0.524
CLV_PCSK_PC7_1 47 53 PF00082 0.511
CLV_Separin_Metazoa 44 48 PF03568 0.586
DEG_Nend_UBRbox_3 1 3 PF02207 0.523
DOC_MAPK_gen_1 33 40 PF00069 0.647
DOC_MAPK_gen_1 51 58 PF00069 0.538
DOC_MAPK_MEF2A_6 33 40 PF00069 0.647
DOC_MAPK_MEF2A_6 51 58 PF00069 0.538
DOC_MAPK_NFAT4_5 33 41 PF00069 0.645
DOC_MAPK_NFAT4_5 51 59 PF00069 0.543
DOC_MAPK_RevD_3 36 52 PF00069 0.616
DOC_USP7_MATH_1 10 14 PF00917 0.449
DOC_USP7_MATH_1 115 119 PF00917 0.608
DOC_WW_Pin1_4 90 95 PF00397 0.519
LIG_FHA_1 115 121 PF00498 0.601
LIG_FHA_1 94 100 PF00498 0.575
LIG_Integrin_isoDGR_2 49 51 PF01839 0.528
LIG_LIR_Gen_1 13 19 PF02991 0.495
LIG_LIR_Nem_3 13 18 PF02991 0.492
LIG_SH2_STAP1 5 9 PF00017 0.476
MOD_CK1_1 21 27 PF00069 0.631
MOD_CK2_1 130 136 PF00069 0.587
MOD_Cter_Amidation 49 52 PF01082 0.519
MOD_GlcNHglycan 82 85 PF01048 0.549
MOD_GSK3_1 107 114 PF00069 0.583
MOD_N-GLC_1 66 71 PF02516 0.626
MOD_NEK2_1 105 110 PF00069 0.555
MOD_NEK2_1 66 71 PF00069 0.544
MOD_NEK2_2 10 15 PF00069 0.469
MOD_PIKK_1 107 113 PF00454 0.560
MOD_PIKK_1 115 121 PF00454 0.606
MOD_PIKK_1 26 32 PF00454 0.513
MOD_PIKK_1 93 99 PF00454 0.517
MOD_Plk_1 66 72 PF00069 0.620
MOD_Plk_2-3 130 136 PF00069 0.693
MOD_Plk_4 10 16 PF00069 0.496
MOD_Plk_4 21 27 PF00069 0.524
MOD_ProDKin_1 90 96 PF00069 0.520
MOD_SUMO_for_1 41 44 PF00179 0.628
TRG_DiLeu_BaLyEn_6 52 57 PF01217 0.526

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I494 Leptomonas seymouri 83% 100%
A0A0S4J787 Bodo saltans 64% 100%
A0A1X0NUE5 Trypanosomatidae 75% 100%
A0A3Q8IGY2 Leishmania donovani 93% 100%
A0A3S5IR91 Trypanosoma rangeli 72% 100%
A4HKD1 Leishmania braziliensis 87% 100%
A4I7W1 Leishmania infantum 94% 100%
D0AA24 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 72% 100%
Q4Q5D8 Leishmania major 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS