Maf-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Maf-like protein

Gene product:

Maf-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9B2M8_LEIMU

TriTrypDb:

LmxM.31.1030

Length:

221

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2M8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2M8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	10
GO:0016462	pyrophosphatase activity	5	10
GO:0016787	hydrolase activity	2	10
GO:0016817	hydrolase activity, acting on acid anhydrides	3	10
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	10
GO:0047429	nucleoside triphosphate diphosphatase activity	6	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	177	179	PF00082	0.316
CLV_PCSK_PC1ET2_1	177	179	PF00082	0.278
CLV_PCSK_SKI1_1	200	204	PF00082	0.309
DEG_APCC_DBOX_1	199	207	PF00400	0.507
DEG_Nend_UBRbox_3	1	3	PF02207	0.454
DOC_ANK_TNKS_1	207	214	PF00023	0.367
DOC_MAPK_gen_1	177	183	PF00069	0.508
DOC_MAPK_MEF2A_6	78	86	PF00069	0.509
DOC_USP7_MATH_1	212	216	PF00917	0.401
DOC_USP7_UBL2_3	99	103	PF12436	0.386
DOC_WW_Pin1_4	30	35	PF00397	0.468
LIG_14-3-3_CanoR_1	133	138	PF00244	0.386
LIG_AP2alpha_2	45	47	PF02296	0.441
LIG_BRCT_BRCA1_1	43	47	PF00533	0.470
LIG_FHA_1	121	127	PF00498	0.441
LIG_FHA_1	24	30	PF00498	0.494
LIG_FHA_1	48	54	PF00498	0.445
LIG_FHA_2	185	191	PF00498	0.507
LIG_LIR_Apic_2	28	34	PF02991	0.486
LIG_LIR_Gen_1	26	34	PF02991	0.428
LIG_LIR_Gen_1	85	92	PF02991	0.424
LIG_LIR_Nem_3	143	148	PF02991	0.426
LIG_LIR_Nem_3	26	30	PF02991	0.411
LIG_LIR_Nem_3	85	89	PF02991	0.424
LIG_SH2_CRK	27	31	PF00017	0.507
LIG_SH2_NCK_1	27	31	PF00017	0.507
LIG_SH2_STAP1	27	31	PF00017	0.507
LIG_SH2_STAT5	31	34	PF00017	0.507
LIG_SH3_3	132	138	PF00018	0.500
LIG_SH3_4	99	106	PF00018	0.445
LIG_TRAF2_1	187	190	PF00917	0.511
LIG_TYR_ITSM	141	148	PF00017	0.507
MOD_CK1_1	112	118	PF00069	0.480
MOD_CK2_1	184	190	PF00069	0.510
MOD_GlcNHglycan	10	13	PF01048	0.244
MOD_GlcNHglycan	216	219	PF01048	0.480
MOD_GSK3_1	117	124	PF00069	0.475
MOD_GSK3_1	133	140	PF00069	0.505
MOD_GSK3_1	41	48	PF00069	0.510
MOD_GSK3_1	78	85	PF00069	0.489
MOD_N-GLC_1	138	143	PF02516	0.267
MOD_NEK2_1	109	114	PF00069	0.457
MOD_NEK2_1	47	52	PF00069	0.444
MOD_NEK2_2	195	200	PF00069	0.478
MOD_PK_1	78	84	PF00069	0.478
MOD_PKA_2	41	47	PF00069	0.470
MOD_Plk_1	138	144	PF00069	0.498
MOD_Plk_1	149	155	PF00069	0.478
MOD_Plk_1	195	201	PF00069	0.510
MOD_Plk_2-3	184	190	PF00069	0.478
MOD_Plk_4	117	123	PF00069	0.480
MOD_Plk_4	140	146	PF00069	0.434
MOD_ProDKin_1	30	36	PF00069	0.468
MOD_SUMO_rev_2	175	183	PF00179	0.485
MOD_SUMO_rev_2	33	41	PF00179	0.458
TRG_ENDOCYTIC_2	145	148	PF00928	0.507
TRG_ENDOCYTIC_2	27	30	PF00928	0.467
TRG_Pf-PMV_PEXEL_1	200	204	PF00026	0.307
TRG_Pf-PMV_PEXEL_1	51	55	PF00026	0.244

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PGQ1	Leptomonas seymouri	67%	100%
A0A0S4KKD9	Bodo saltans	27%	80%
A0A1X0NW04	Trypanosomatidae	38%	100%
A0A3Q8IGW3	Leishmania donovani	92%	100%
A0A3R7M9P1	Trypanosoma rangeli	42%	100%
A4HK85	Leishmania braziliensis	84%	100%
A4I7S0	Leishmania infantum	92%	100%
B0B7R8	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	27%	100%
B0BBY3	Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)	27%	100%
B2J6P8	Nostoc punctiforme (strain ATCC 29133 / PCC 73102)	23%	100%
D0A9X9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
O84353	Chlamydia trachomatis (strain D/UW-3/Cx)	27%	100%
P58632	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	25%	100%
Q253S7	Chlamydia felis (strain Fe/C-56)	27%	100%
Q3KM09	Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13)	27%	100%
Q4Q5H9	Leishmania major	90%	100%
Q54TC5	Dictyostelium discoideum	34%	100%
Q823U1	Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)	26%	100%
Q9PK45	Chlamydia muridarum (strain MoPn / Nigg)	27%	100%