Staphylococcal nuclease domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Staphylococcal nuclease homologue/Tudor domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B2L9_LEIMU

TriTrypDb:

LmxM.31.0950

Length:

934

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 4
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	11
GO:0016442	RISC complex	4	11
GO:0031332	RNAi effector complex	3	11
GO:0032991	protein-containing complex	1	11
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11
GO:0005634	nucleus	5	1
GO:0005829	cytosol	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

E9B2L9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2L9

Function

Biological processes
Term	Name	Level	Count
GO:0009892	negative regulation of metabolic process	4	11
GO:0010468	regulation of gene expression	5	11
GO:0010605	negative regulation of macromolecule metabolic process	5	11
GO:0010629	negative regulation of gene expression	6	11
GO:0019222	regulation of metabolic process	3	11
GO:0031047	RNA-mediated gene silencing	7	11
GO:0048519	negative regulation of biological process	3	11
GO:0050789	regulation of biological process	2	11
GO:0060255	regulation of macromolecule metabolic process	4	11
GO:0065007	biological regulation	1	11
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004518	nuclease activity	4	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	205	209	PF00656	0.642
CLV_C14_Caspase3-7	236	240	PF00656	0.332
CLV_C14_Caspase3-7	345	349	PF00656	0.564
CLV_C14_Caspase3-7	848	852	PF00656	0.418
CLV_C14_Caspase3-7	928	932	PF00656	0.461
CLV_NRD_NRD_1	136	138	PF00675	0.441
CLV_NRD_NRD_1	42	44	PF00675	0.332
CLV_NRD_NRD_1	894	896	PF00675	0.558
CLV_NRD_NRD_1	914	916	PF00675	0.422
CLV_PCSK_KEX2_1	291	293	PF00082	0.400
CLV_PCSK_KEX2_1	42	44	PF00082	0.297
CLV_PCSK_KEX2_1	681	683	PF00082	0.608
CLV_PCSK_KEX2_1	894	896	PF00082	0.558
CLV_PCSK_PC1ET2_1	291	293	PF00082	0.369
CLV_PCSK_PC1ET2_1	681	683	PF00082	0.488
CLV_PCSK_SKI1_1	13	17	PF00082	0.488
CLV_PCSK_SKI1_1	138	142	PF00082	0.343
CLV_PCSK_SKI1_1	421	425	PF00082	0.297
CLV_PCSK_SKI1_1	607	611	PF00082	0.461
CLV_PCSK_SKI1_1	666	670	PF00082	0.443
CLV_PCSK_SKI1_1	682	686	PF00082	0.464
DEG_APCC_DBOX_1	385	393	PF00400	0.313
DEG_APCC_DBOX_1	526	534	PF00400	0.534
DEG_APCC_DBOX_1	860	868	PF00400	0.421
DEG_APCC_KENBOX_2	563	567	PF00400	0.450
DEG_COP1_1	870	880	PF00400	0.461
DEG_SPOP_SBC_1	179	183	PF00917	0.242
DOC_CDC14_PxL_1	34	42	PF14671	0.332
DOC_CKS1_1	317	322	PF01111	0.520
DOC_CKS1_1	576	581	PF01111	0.313
DOC_CYCLIN_RxL_1	134	144	PF00134	0.451
DOC_CYCLIN_RxL_1	884	893	PF00134	0.511
DOC_CYCLIN_yCln2_LP_2	16	22	PF00134	0.308
DOC_MAPK_DCC_7	297	305	PF00069	0.520
DOC_MAPK_gen_1	525	532	PF00069	0.394
DOC_MAPK_gen_1	780	788	PF00069	0.477
DOC_MAPK_MEF2A_6	266	274	PF00069	0.325
DOC_MAPK_MEF2A_6	458	466	PF00069	0.427
DOC_MAPK_MEF2A_6	546	553	PF00069	0.407
DOC_MAPK_MEF2A_6	564	573	PF00069	0.300
DOC_PP1_RVXF_1	430	437	PF00149	0.398
DOC_PP1_RVXF_1	68	75	PF00149	0.297
DOC_PP1_RVXF_1	785	792	PF00149	0.480
DOC_PP2B_LxvP_1	776	779	PF13499	0.563
DOC_PP4_FxxP_1	567	570	PF00568	0.337
DOC_USP7_MATH_1	284	288	PF00917	0.240
DOC_USP7_MATH_1	7	11	PF00917	0.415
DOC_USP7_UBL2_3	262	266	PF12436	0.373
DOC_USP7_UBL2_3	498	502	PF12436	0.447
DOC_USP7_UBL2_3	681	685	PF12436	0.345
DOC_USP7_UBL2_3	783	787	PF12436	0.533
DOC_WW_Pin1_4	316	321	PF00397	0.716
DOC_WW_Pin1_4	324	329	PF00397	0.703
DOC_WW_Pin1_4	347	352	PF00397	0.693
DOC_WW_Pin1_4	403	408	PF00397	0.297
DOC_WW_Pin1_4	47	52	PF00397	0.441
DOC_WW_Pin1_4	505	510	PF00397	0.526
DOC_WW_Pin1_4	575	580	PF00397	0.313
DOC_WW_Pin1_4	750	755	PF00397	0.528
DOC_WW_Pin1_4	814	819	PF00397	0.494
LIG_14-3-3_CanoR_1	150	156	PF00244	0.547
LIG_14-3-3_CanoR_1	386	390	PF00244	0.324
LIG_14-3-3_CanoR_1	410	414	PF00244	0.301
LIG_14-3-3_CanoR_1	42	49	PF00244	0.334
LIG_14-3-3_CanoR_1	450	456	PF00244	0.418
LIG_14-3-3_CanoR_1	527	533	PF00244	0.541
LIG_14-3-3_CanoR_1	607	612	PF00244	0.207
LIG_14-3-3_CanoR_1	64	68	PF00244	0.313
LIG_14-3-3_CanoR_1	745	754	PF00244	0.385
LIG_14-3-3_CanoR_1	772	776	PF00244	0.579
LIG_14-3-3_CanoR_1	894	901	PF00244	0.549
LIG_Actin_WH2_2	530	548	PF00022	0.418
LIG_Actin_WH2_2	816	832	PF00022	0.527
LIG_AP2alpha_2	590	592	PF02296	0.357
LIG_APCC_ABBA_1	433	438	PF00400	0.240
LIG_APCC_ABBAyCdc20_2	432	438	PF00400	0.240
LIG_APCC_ABBAyCdc20_2	501	507	PF00400	0.325
LIG_BIR_II_1	1	5	PF00653	0.411
LIG_BIR_III_4	379	383	PF00653	0.551
LIG_BRCT_BRCA1_1	45	49	PF00533	0.325
LIG_CAP-Gly_1	928	934	PF01302	0.689
LIG_CtBP_PxDLS_1	157	161	PF00389	0.488
LIG_deltaCOP1_diTrp_1	415	423	PF00928	0.313
LIG_EH1_1	219	227	PF00400	0.373
LIG_eIF4E_1	57	63	PF01652	0.444
LIG_FHA_1	181	187	PF00498	0.408
LIG_FHA_1	196	202	PF00498	0.485
LIG_FHA_1	269	275	PF00498	0.380
LIG_FHA_1	27	33	PF00498	0.261
LIG_FHA_1	354	360	PF00498	0.512
LIG_FHA_1	371	377	PF00498	0.347
LIG_FHA_1	444	450	PF00498	0.378
LIG_FHA_1	473	479	PF00498	0.300
LIG_FHA_1	608	614	PF00498	0.388
LIG_FHA_1	674	680	PF00498	0.540
LIG_FHA_1	792	798	PF00498	0.545
LIG_FHA_1	894	900	PF00498	0.470
LIG_FHA_1	97	103	PF00498	0.373
LIG_FHA_2	107	113	PF00498	0.333
LIG_FHA_2	203	209	PF00498	0.460
LIG_FHA_2	274	280	PF00498	0.464
LIG_FHA_2	325	331	PF00498	0.514
LIG_FHA_2	343	349	PF00498	0.641
LIG_FHA_2	410	416	PF00498	0.334
LIG_FHA_2	48	54	PF00498	0.402
LIG_FHA_2	625	631	PF00498	0.434
LIG_FHA_2	870	876	PF00498	0.378
LIG_KLC1_Yacidic_2	76	81	PF13176	0.441
LIG_LIR_Apic_2	565	570	PF02991	0.352
LIG_LIR_Gen_1	124	133	PF02991	0.358
LIG_LIR_Gen_1	239	249	PF02991	0.391
LIG_LIR_Gen_1	261	272	PF02991	0.357
LIG_LIR_Gen_1	438	444	PF02991	0.413
LIG_LIR_Gen_1	470	478	PF02991	0.297
LIG_LIR_Gen_1	526	537	PF02991	0.532
LIG_LIR_Gen_1	641	649	PF02991	0.364
LIG_LIR_Gen_1	785	795	PF02991	0.528
LIG_LIR_Gen_1	810	819	PF02991	0.493
LIG_LIR_Gen_1	842	849	PF02991	0.546
LIG_LIR_Nem_3	121	126	PF02991	0.324
LIG_LIR_Nem_3	2	6	PF02991	0.350
LIG_LIR_Nem_3	239	244	PF02991	0.302
LIG_LIR_Nem_3	26	30	PF02991	0.518
LIG_LIR_Nem_3	261	267	PF02991	0.357
LIG_LIR_Nem_3	412	416	PF02991	0.297
LIG_LIR_Nem_3	438	442	PF02991	0.413
LIG_LIR_Nem_3	470	476	PF02991	0.297
LIG_LIR_Nem_3	526	532	PF02991	0.520
LIG_LIR_Nem_3	641	646	PF02991	0.364
LIG_LIR_Nem_3	705	711	PF02991	0.400
LIG_LIR_Nem_3	785	791	PF02991	0.471
LIG_LIR_Nem_3	810	814	PF02991	0.489
LIG_LIR_Nem_3	817	823	PF02991	0.475
LIG_LIR_Nem_3	842	846	PF02991	0.487
LIG_PTB_Apo_2	863	870	PF02174	0.423
LIG_PTB_Phospho_1	863	869	PF10480	0.428
LIG_REV1ctd_RIR_1	218	228	PF16727	0.373
LIG_REV1ctd_RIR_1	474	484	PF16727	0.357
LIG_SH2_CRK	264	268	PF00017	0.278
LIG_SH2_CRK	355	359	PF00017	0.434
LIG_SH2_CRK	439	443	PF00017	0.391
LIG_SH2_CRK	811	815	PF00017	0.533
LIG_SH2_NCK_1	264	268	PF00017	0.192
LIG_SH2_NCK_1	57	61	PF00017	0.441
LIG_SH2_NCK_1	843	847	PF00017	0.464
LIG_SH2_PTP2	299	302	PF00017	0.611
LIG_SH2_SRC	299	302	PF00017	0.562
LIG_SH2_SRC	79	82	PF00017	0.441
LIG_SH2_STAP1	416	420	PF00017	0.297
LIG_SH2_STAP1	439	443	PF00017	0.357
LIG_SH2_STAP1	473	477	PF00017	0.357
LIG_SH2_STAP1	55	59	PF00017	0.441
LIG_SH2_STAT5	299	302	PF00017	0.611
LIG_SH2_STAT5	3	6	PF00017	0.349
LIG_SH2_STAT5	34	37	PF00017	0.391
LIG_SH2_STAT5	355	358	PF00017	0.560
LIG_SH2_STAT5	428	431	PF00017	0.323
LIG_SH2_STAT5	529	532	PF00017	0.422
LIG_SH2_STAT5	561	564	PF00017	0.387
LIG_SH2_STAT5	724	727	PF00017	0.495
LIG_SH2_STAT5	79	82	PF00017	0.316
LIG_SH2_STAT5	828	831	PF00017	0.465
LIG_SH2_STAT5	869	872	PF00017	0.390
LIG_SH3_1	506	512	PF00018	0.528
LIG_SH3_1	803	809	PF00018	0.482
LIG_SH3_1	828	834	PF00018	0.324
LIG_SH3_2	509	514	PF14604	0.585
LIG_SH3_3	267	273	PF00018	0.192
LIG_SH3_3	301	307	PF00018	0.670
LIG_SH3_3	314	320	PF00018	0.581
LIG_SH3_3	328	334	PF00018	0.765
LIG_SH3_3	48	54	PF00018	0.357
LIG_SH3_3	506	512	PF00018	0.567
LIG_SH3_3	549	555	PF00018	0.392
LIG_SH3_3	557	563	PF00018	0.309
LIG_SH3_3	803	809	PF00018	0.497
LIG_SH3_3	828	834	PF00018	0.318
LIG_SUMO_SIM_anti_2	181	188	PF11976	0.437
LIG_SUMO_SIM_anti_2	635	641	PF11976	0.441
LIG_SUMO_SIM_par_1	181	188	PF11976	0.382
LIG_SUMO_SIM_par_1	244	251	PF11976	0.441
LIG_SUMO_SIM_par_1	28	33	PF11976	0.271
LIG_SUMO_SIM_par_1	372	379	PF11976	0.456
LIG_TRAF2_1	156	159	PF00917	0.528
LIG_TRAF2_1	254	257	PF00917	0.373
LIG_TRAF2_1	492	495	PF00917	0.446
LIG_TRAF2_1	497	500	PF00917	0.440
LIG_TRAF2_1	50	53	PF00917	0.441
LIG_TRAF2_1	845	848	PF00917	0.506
LIG_TRAF2_1	909	912	PF00917	0.546
LIG_TYR_ITIM	233	238	PF00017	0.441
LIG_TYR_ITIM	437	442	PF00017	0.369
LIG_UBA3_1	184	190	PF00899	0.536
LIG_UBA3_1	245	252	PF00899	0.373
LIG_UBA3_1	31	39	PF00899	0.192
LIG_WRC_WIRS_1	473	478	PF05994	0.313
LIG_WRC_WIRS_1	529	534	PF05994	0.391
LIG_WW_3	114	118	PF00397	0.391
MOD_CDK_SPK_2	750	755	PF00069	0.528
MOD_CDK_SPxK_1	750	756	PF00069	0.528
MOD_CDK_SPxxK_3	403	410	PF00069	0.297
MOD_CK1_1	127	133	PF00069	0.430
MOD_CK1_1	247	253	PF00069	0.297
MOD_CK1_1	406	412	PF00069	0.330
MOD_CK1_1	485	491	PF00069	0.334
MOD_CK1_1	624	630	PF00069	0.419
MOD_CK1_1	762	768	PF00069	0.385
MOD_CK2_1	171	177	PF00069	0.498
MOD_CK2_1	185	191	PF00069	0.500
MOD_CK2_1	251	257	PF00069	0.373
MOD_CK2_1	47	53	PF00069	0.350
MOD_CK2_1	847	853	PF00069	0.482
MOD_CK2_1	869	875	PF00069	0.382
MOD_CK2_1	876	882	PF00069	0.423
MOD_GlcNHglycan	129	132	PF01048	0.401
MOD_GlcNHglycan	141	144	PF01048	0.485
MOD_GlcNHglycan	282	285	PF01048	0.513
MOD_GlcNHglycan	286	289	PF01048	0.475
MOD_GlcNHglycan	378	383	PF01048	0.558
MOD_GlcNHglycan	45	48	PF01048	0.513
MOD_GlcNHglycan	579	582	PF01048	0.453
MOD_GlcNHglycan	673	676	PF01048	0.509
MOD_GlcNHglycan	748	751	PF01048	0.259
MOD_GlcNHglycan	764	767	PF01048	0.378
MOD_GlcNHglycan	85	88	PF01048	0.353
MOD_GlcNHglycan	896	899	PF01048	0.481
MOD_GlcNHglycan	9	12	PF01048	0.315
MOD_GSK3_1	195	202	PF00069	0.400
MOD_GSK3_1	244	251	PF00069	0.299
MOD_GSK3_1	26	33	PF00069	0.332
MOD_GSK3_1	268	275	PF00069	0.325
MOD_GSK3_1	280	287	PF00069	0.313
MOD_GSK3_1	43	50	PF00069	0.502
MOD_GSK3_1	746	753	PF00069	0.447
MOD_GSK3_1	762	769	PF00069	0.563
MOD_GSK3_1	876	883	PF00069	0.392
MOD_N-GLC_1	268	273	PF02516	0.360
MOD_N-GLC_1	607	612	PF02516	0.450
MOD_N-GLC_1	632	637	PF02516	0.357
MOD_N-GLC_1	743	748	PF02516	0.363
MOD_NEK2_1	129	134	PF00069	0.498
MOD_NEK2_1	185	190	PF00069	0.388
MOD_NEK2_1	192	197	PF00069	0.362
MOD_NEK2_1	361	366	PF00069	0.388
MOD_NEK2_1	385	390	PF00069	0.488
MOD_NEK2_1	423	428	PF00069	0.393
MOD_NEK2_1	457	462	PF00069	0.326
MOD_NEK2_1	521	526	PF00069	0.492
MOD_NEK2_1	62	67	PF00069	0.333
MOD_NEK2_1	622	627	PF00069	0.347
MOD_NEK2_1	83	88	PF00069	0.372
MOD_NEK2_1	880	885	PF00069	0.449
MOD_NEK2_2	472	477	PF00069	0.357
MOD_PIKK_1	124	130	PF00454	0.426
MOD_PIKK_1	192	198	PF00454	0.462
MOD_PIKK_1	759	765	PF00454	0.385
MOD_PKA_1	894	900	PF00069	0.495
MOD_PKA_2	385	391	PF00069	0.337
MOD_PKA_2	392	398	PF00069	0.300
MOD_PKA_2	409	415	PF00069	0.318
MOD_PKA_2	41	47	PF00069	0.345
MOD_PKA_2	63	69	PF00069	0.313
MOD_PKA_2	771	777	PF00069	0.567
MOD_PKA_2	893	899	PF00069	0.561
MOD_Plk_1	210	216	PF00069	0.518
MOD_Plk_1	268	274	PF00069	0.393
MOD_Plk_1	414	420	PF00069	0.455
MOD_Plk_1	607	613	PF00069	0.444
MOD_Plk_1	632	638	PF00069	0.358
MOD_Plk_1	743	749	PF00069	0.516
MOD_Plk_1	766	772	PF00069	0.469
MOD_Plk_2-3	847	853	PF00069	0.474
MOD_Plk_4	180	186	PF00069	0.394
MOD_Plk_4	26	32	PF00069	0.373
MOD_Plk_4	361	367	PF00069	0.447
MOD_Plk_4	370	376	PF00069	0.392
MOD_Plk_4	472	478	PF00069	0.346
MOD_Plk_4	528	534	PF00069	0.425
MOD_Plk_4	63	69	PF00069	0.332
MOD_Plk_4	634	640	PF00069	0.227
MOD_Plk_4	719	725	PF00069	0.450
MOD_Plk_4	771	777	PF00069	0.561
MOD_Plk_4	880	886	PF00069	0.415
MOD_ProDKin_1	316	322	PF00069	0.713
MOD_ProDKin_1	324	330	PF00069	0.703
MOD_ProDKin_1	347	353	PF00069	0.690
MOD_ProDKin_1	403	409	PF00069	0.297
MOD_ProDKin_1	47	53	PF00069	0.441
MOD_ProDKin_1	505	511	PF00069	0.527
MOD_ProDKin_1	575	581	PF00069	0.313
MOD_ProDKin_1	750	756	PF00069	0.528
MOD_ProDKin_1	814	820	PF00069	0.486
MOD_SUMO_for_1	497	500	PF00179	0.441
MOD_SUMO_for_1	684	687	PF00179	0.527
MOD_SUMO_rev_2	211	221	PF00179	0.446
MOD_SUMO_rev_2	325	334	PF00179	0.805
MOD_SUMO_rev_2	415	423	PF00179	0.381
MOD_SUMO_rev_2	494	504	PF00179	0.419
MOD_SUMO_rev_2	590	599	PF00179	0.297
MOD_SUMO_rev_2	781	789	PF00179	0.480
TRG_DiLeu_BaEn_1	58	63	PF01217	0.343
TRG_DiLeu_BaEn_2	216	222	PF01217	0.373
TRG_DiLeu_BaEn_2	418	424	PF01217	0.313
TRG_DiLeu_BaLyEn_6	221	226	PF01217	0.441
TRG_ENDOCYTIC_2	126	129	PF00928	0.313
TRG_ENDOCYTIC_2	235	238	PF00928	0.404
TRG_ENDOCYTIC_2	264	267	PF00928	0.395
TRG_ENDOCYTIC_2	439	442	PF00928	0.391
TRG_ENDOCYTIC_2	473	476	PF00928	0.297
TRG_ENDOCYTIC_2	529	532	PF00928	0.422
TRG_ENDOCYTIC_2	811	814	PF00928	0.530
TRG_ENDOCYTIC_2	843	846	PF00928	0.459
TRG_ENDOCYTIC_2	868	871	PF00928	0.371
TRG_ENDOCYTIC_2	924	927	PF00928	0.509
TRG_ER_diArg_1	424	427	PF00400	0.441
TRG_ER_diArg_1	525	528	PF00400	0.534
TRG_NLS_MonoCore_2	288	293	PF00514	0.325
TRG_NLS_MonoExtN_4	289	294	PF00514	0.325
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.373

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMX5	Leptomonas seymouri	76%	99%
A0A0S4KLR8	Bodo saltans	40%	100%
A0A1X0NW15	Trypanosomatidae	52%	100%
A0A3Q8IFE0	Leishmania donovani	92%	100%
A0A3R7K553	Trypanosoma rangeli	51%	100%
A4HK76	Leishmania braziliensis	85%	100%
A4I7R1	Leishmania infantum	92%	100%
D0A9W6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
Q4Q5I7	Leishmania major	93%	100%
Q5REU4	Pongo abelii	29%	100%
Q66X93	Rattus norvegicus	28%	100%
Q78PY7	Mus musculus	28%	100%
Q7KZF4	Homo sapiens	28%	100%
Q7ZT42	Danio rerio	28%	100%
Q863B3	Bos taurus	28%	100%
Q8VZG7	Arabidopsis thaliana	27%	94%
Q9FLT0	Arabidopsis thaliana	27%	95%
Q9W0S7	Drosophila melanogaster	27%	100%
Q9Y7U7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
V5BL57	Trypanosoma cruzi	49%	100%