Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B2K7_LEIMU

TriTrypDb:

LmxM.31.0830

Length:

469

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2K7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2K7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	304	308	PF00656	0.578
CLV_C14_Caspase3-7	376	380	PF00656	0.716
CLV_NRD_NRD_1	114	116	PF00675	0.495
CLV_NRD_NRD_1	188	190	PF00675	0.521
CLV_NRD_NRD_1	193	195	PF00675	0.483
CLV_NRD_NRD_1	262	264	PF00675	0.571
CLV_NRD_NRD_1	82	84	PF00675	0.321
CLV_PCSK_KEX2_1	114	116	PF00082	0.495
CLV_PCSK_KEX2_1	187	189	PF00082	0.447
CLV_PCSK_KEX2_1	192	194	PF00082	0.479
CLV_PCSK_KEX2_1	82	84	PF00082	0.321
CLV_PCSK_PC7_1	188	194	PF00082	0.468
CLV_PCSK_SKI1_1	114	118	PF00082	0.599
CLV_PCSK_SKI1_1	170	174	PF00082	0.432
CLV_PCSK_SKI1_1	194	198	PF00082	0.633
CLV_PCSK_SKI1_1	453	457	PF00082	0.645
CLV_PCSK_SKI1_1	67	71	PF00082	0.556
CLV_Separin_Metazoa	401	405	PF03568	0.538
DEG_APCC_DBOX_1	193	201	PF00400	0.599
DEG_ODPH_VHL_1	173	185	PF01847	0.503
DEG_SPOP_SBC_1	369	373	PF00917	0.758
DOC_CKS1_1	459	464	PF01111	0.650
DOC_MAPK_gen_1	114	121	PF00069	0.488
DOC_MAPK_gen_1	177	185	PF00069	0.520
DOC_MAPK_gen_1	187	197	PF00069	0.482
DOC_MAPK_MEF2A_6	114	121	PF00069	0.488
DOC_MAPK_MEF2A_6	42	51	PF00069	0.409
DOC_PP1_RVXF_1	124	131	PF00149	0.593
DOC_PP4_FxxP_1	285	288	PF00568	0.652
DOC_PP4_FxxP_1	289	292	PF00568	0.662
DOC_PP4_FxxP_1	459	462	PF00568	0.664
DOC_PP4_FxxP_1	77	80	PF00568	0.586
DOC_USP7_MATH_1	203	207	PF00917	0.662
DOC_USP7_MATH_1	212	216	PF00917	0.600
DOC_USP7_MATH_1	325	329	PF00917	0.710
DOC_USP7_MATH_1	340	344	PF00917	0.739
DOC_USP7_MATH_1	354	358	PF00917	0.690
DOC_USP7_MATH_1	36	40	PF00917	0.738
DOC_USP7_MATH_1	429	433	PF00917	0.678
DOC_USP7_MATH_1	95	99	PF00917	0.535
DOC_USP7_MATH_2	316	322	PF00917	0.755
DOC_WW_Pin1_4	100	105	PF00397	0.602
DOC_WW_Pin1_4	165	170	PF00397	0.728
DOC_WW_Pin1_4	178	183	PF00397	0.439
DOC_WW_Pin1_4	18	23	PF00397	0.818
DOC_WW_Pin1_4	305	310	PF00397	0.615
DOC_WW_Pin1_4	341	346	PF00397	0.823
DOC_WW_Pin1_4	393	398	PF00397	0.698
DOC_WW_Pin1_4	420	425	PF00397	0.689
DOC_WW_Pin1_4	458	463	PF00397	0.737
DOC_WW_Pin1_4	5	10	PF00397	0.769
LIG_14-3-3_CanoR_1	114	120	PF00244	0.553
LIG_14-3-3_CanoR_1	277	285	PF00244	0.629
LIG_14-3-3_CanoR_1	453	462	PF00244	0.654
LIG_14-3-3_CanoR_1	67	75	PF00244	0.576
LIG_BIR_II_1	1	5	PF00653	0.711
LIG_deltaCOP1_diTrp_1	50	57	PF00928	0.420
LIG_EH_1	286	290	PF12763	0.651
LIG_FHA_1	116	122	PF00498	0.524
LIG_FHA_1	205	211	PF00498	0.614
LIG_FHA_1	434	440	PF00498	0.573
LIG_FHA_1	44	50	PF00498	0.455
LIG_FHA_1	5	11	PF00498	0.534
LIG_FHA_2	346	352	PF00498	0.788
LIG_FHA_2	386	392	PF00498	0.818
LIG_FHA_2	394	400	PF00498	0.823
LIG_FHA_2	446	452	PF00498	0.627
LIG_FHA_2	9	15	PF00498	0.661
LIG_LIR_Apic_2	284	288	PF02991	0.655
LIG_LIR_Apic_2	457	462	PF02991	0.661
LIG_LIR_Gen_1	46	53	PF02991	0.412
LIG_LIR_Gen_1	93	104	PF02991	0.656
LIG_LIR_Nem_3	293	298	PF02991	0.626
LIG_LIR_Nem_3	449	455	PF02991	0.628
LIG_LIR_Nem_3	46	51	PF02991	0.339
LIG_LIR_Nem_3	93	99	PF02991	0.522
LIG_LYPXL_yS_3	58	61	PF13949	0.649
LIG_NBox_RRM_1	320	330	PF00076	0.749
LIG_Pex14_2	130	134	PF04695	0.294
LIG_Pex14_2	285	289	PF04695	0.684
LIG_Pex14_2	452	456	PF04695	0.641
LIG_Pex14_2	92	96	PF04695	0.612
LIG_PTB_Apo_2	279	286	PF02174	0.658
LIG_SH2_STAP1	370	374	PF00017	0.802
LIG_SH2_STAT3	148	151	PF00017	0.502
LIG_SH2_STAT5	222	225	PF00017	0.542
LIG_SH3_2	109	114	PF14604	0.534
LIG_SH3_3	106	112	PF00018	0.532
LIG_SH3_3	116	122	PF00018	0.476
LIG_SH3_3	169	175	PF00018	0.674
LIG_SH3_3	197	203	PF00018	0.658
LIG_SH3_3	339	345	PF00018	0.818
LIG_SH3_3	421	427	PF00018	0.656
LIG_SH3_3	98	104	PF00018	0.633
LIG_SH3_5	462	466	PF00018	0.495
LIG_TRAF2_1	258	261	PF00917	0.537
LIG_TRAF2_1	316	319	PF00917	0.530
LIG_WW_3	21	25	PF00397	0.534
MOD_CDC14_SPxK_1	21	24	PF00782	0.760
MOD_CDK_SPK_2	165	170	PF00069	0.458
MOD_CDK_SPxK_1	18	24	PF00069	0.767
MOD_CDK_SPxxK_3	5	12	PF00069	0.660
MOD_CK1_1	2	8	PF00069	0.732
MOD_CK1_1	221	227	PF00069	0.641
MOD_CK1_1	25	31	PF00069	0.721
MOD_CK1_1	333	339	PF00069	0.681
MOD_CK1_1	357	363	PF00069	0.737
MOD_CK1_1	395	401	PF00069	0.755
MOD_CK1_1	422	428	PF00069	0.680
MOD_CK2_1	165	171	PF00069	0.449
MOD_CK2_1	221	227	PF00069	0.607
MOD_CK2_1	385	391	PF00069	0.749
MOD_CK2_1	395	401	PF00069	0.664
MOD_CK2_1	8	14	PF00069	0.739
MOD_GlcNHglycan	24	27	PF01048	0.732
MOD_GlcNHglycan	317	323	PF01048	0.719
MOD_GlcNHglycan	38	41	PF01048	0.664
MOD_GlcNHglycan	462	465	PF01048	0.625
MOD_GSK3_1	152	159	PF00069	0.399
MOD_GSK3_1	18	25	PF00069	0.724
MOD_GSK3_1	26	33	PF00069	0.638
MOD_GSK3_1	273	280	PF00069	0.633
MOD_GSK3_1	341	348	PF00069	0.783
MOD_GSK3_1	350	357	PF00069	0.664
MOD_GSK3_1	369	376	PF00069	0.514
MOD_GSK3_1	4	11	PF00069	0.717
MOD_GSK3_1	429	436	PF00069	0.660
MOD_GSK3_1	454	461	PF00069	0.635
MOD_GSK3_1	63	70	PF00069	0.593
MOD_N-GLC_1	16	21	PF02516	0.636
MOD_N-GLC_1	31	36	PF02516	0.595
MOD_NEK2_1	176	181	PF00069	0.499
MOD_NEK2_1	278	283	PF00069	0.595
MOD_NEK2_1	392	397	PF00069	0.793
MOD_NEK2_1	419	424	PF00069	0.701
MOD_NEK2_2	385	390	PF00069	0.525
MOD_PIKK_1	454	460	PF00454	0.651
MOD_PKA_2	271	277	PF00069	0.605
MOD_PKA_2	278	284	PF00069	0.679
MOD_PKA_2	330	336	PF00069	0.704
MOD_Plk_1	31	37	PF00069	0.548
MOD_Plk_4	218	224	PF00069	0.655
MOD_Plk_4	325	331	PF00069	0.693
MOD_Plk_4	363	369	PF00069	0.536
MOD_Plk_4	43	49	PF00069	0.541
MOD_ProDKin_1	100	106	PF00069	0.597
MOD_ProDKin_1	165	171	PF00069	0.719
MOD_ProDKin_1	178	184	PF00069	0.428
MOD_ProDKin_1	18	24	PF00069	0.820
MOD_ProDKin_1	305	311	PF00069	0.617
MOD_ProDKin_1	341	347	PF00069	0.824
MOD_ProDKin_1	393	399	PF00069	0.700
MOD_ProDKin_1	420	426	PF00069	0.690
MOD_ProDKin_1	458	464	PF00069	0.738
MOD_ProDKin_1	5	11	PF00069	0.770
MOD_SUMO_rev_2	463	469	PF00179	0.657
TRG_ENDOCYTIC_2	125	128	PF00928	0.486
TRG_ENDOCYTIC_2	58	61	PF00928	0.649
TRG_ER_diArg_1	114	116	PF00400	0.495
TRG_ER_diArg_1	186	189	PF00400	0.450
TRG_ER_diArg_1	191	194	PF00400	0.468
TRG_ER_diArg_1	82	84	PF00400	0.321
TRG_ER_FFAT_2	457	465	PF00635	0.581
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.602

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P801	Leptomonas seymouri	47%	98%
A0A3Q8IKU6	Leishmania donovani	87%	100%
A4HK64	Leishmania braziliensis	65%	99%
A4I7P9	Leishmania infantum	88%	100%
Q4Q5J9	Leishmania major	81%	99%