Mut7-C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Mut7-C RNAse domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B2J4_LEIMU

TriTrypDb:

LmxM.31.0710

Length:

296

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2J4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2J4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	155	157	PF00675	0.441
CLV_NRD_NRD_1	193	195	PF00675	0.403
CLV_NRD_NRD_1	289	291	PF00675	0.648
CLV_NRD_NRD_1	293	295	PF00675	0.706
CLV_PCSK_KEX2_1	134	136	PF00082	0.432
CLV_PCSK_KEX2_1	155	157	PF00082	0.460
CLV_PCSK_KEX2_1	289	291	PF00082	0.476
CLV_PCSK_PC1ET2_1	134	136	PF00082	0.444
CLV_PCSK_SKI1_1	121	125	PF00082	0.372
CLV_PCSK_SKI1_1	156	160	PF00082	0.352
CLV_PCSK_SKI1_1	194	198	PF00082	0.401
CLV_PCSK_SKI1_1	246	250	PF00082	0.550
CLV_PCSK_SKI1_1	28	32	PF00082	0.344
CLV_Separin_Metazoa	286	290	PF03568	0.488
DEG_APCC_DBOX_1	231	239	PF00400	0.592
DOC_CYCLIN_RxL_1	246	257	PF00134	0.491
DOC_CYCLIN_RxL_1	28	39	PF00134	0.280
DOC_CYCLIN_yClb5_NLxxxL_5	211	220	PF00134	0.501
DOC_MAPK_gen_1	134	140	PF00069	0.452
DOC_PP1_RVXF_1	192	199	PF00149	0.347
DOC_PP1_RVXF_1	247	254	PF00149	0.484
DOC_USP7_MATH_1	100	104	PF00917	0.392
DOC_WW_Pin1_4	7	12	PF00397	0.590
LIG_14-3-3_CanoR_1	155	165	PF00244	0.373
LIG_14-3-3_CanoR_1	239	245	PF00244	0.487
LIG_14-3-3_CanoR_1	60	69	PF00244	0.444
LIG_14-3-3_CanoR_1	79	84	PF00244	0.222
LIG_BRCT_BRCA1_1	129	133	PF00533	0.444
LIG_Clathr_ClatBox_1	164	168	PF01394	0.386
LIG_DLG_GKlike_1	79	87	PF00625	0.194
LIG_FHA_1	145	151	PF00498	0.444
LIG_FHA_2	157	163	PF00498	0.429
LIG_LIR_Gen_1	182	192	PF02991	0.369
LIG_LIR_Nem_3	182	187	PF02991	0.348
LIG_LIR_Nem_3	210	214	PF02991	0.426
LIG_LIR_Nem_3	243	247	PF02991	0.489
LIG_MAD2	60	68	PF02301	0.429
LIG_PCNA_PIPBox_1	26	35	PF02747	0.485
LIG_Pex14_2	124	128	PF04695	0.444
LIG_Pex14_2	20	24	PF04695	0.369
LIG_Pex14_2	200	204	PF04695	0.518
LIG_SH2_CRK	38	42	PF00017	0.344
LIG_SH2_STAT5	255	258	PF00017	0.521
LIG_SH2_STAT5	32	35	PF00017	0.364
LIG_SH3_3	263	269	PF00018	0.486
LIG_SUMO_SIM_par_1	162	168	PF11976	0.194
LIG_TRAF2_1	227	230	PF00917	0.618
LIG_TYR_ITIM	36	41	PF00017	0.344
LIG_WRC_WIRS_1	208	213	PF05994	0.487
MOD_CK1_1	10	16	PF00069	0.627
MOD_CK1_1	107	113	PF00069	0.379
MOD_CK1_1	210	216	PF00069	0.457
MOD_CK1_1	281	287	PF00069	0.589
MOD_CK2_1	100	106	PF00069	0.344
MOD_CK2_1	156	162	PF00069	0.444
MOD_CK2_1	251	257	PF00069	0.534
MOD_GSK3_1	100	107	PF00069	0.344
MOD_GSK3_1	3	10	PF00069	0.653
MOD_N-GLC_1	3	8	PF02516	0.671
MOD_NEK2_1	216	221	PF00069	0.470
MOD_NEK2_1	22	27	PF00069	0.335
MOD_NEK2_1	251	256	PF00069	0.487
MOD_NEK2_1	69	74	PF00069	0.405
MOD_PIKK_1	122	128	PF00454	0.485
MOD_PKA_2	233	239	PF00069	0.520
MOD_PKA_2	281	287	PF00069	0.589
MOD_Plk_1	22	28	PF00069	0.344
MOD_Plk_1	230	236	PF00069	0.564
MOD_Plk_4	104	110	PF00069	0.384
MOD_Plk_4	260	266	PF00069	0.433
MOD_ProDKin_1	7	13	PF00069	0.588
MOD_SUMO_rev_2	130	136	PF00179	0.454
MOD_SUMO_rev_2	273	281	PF00179	0.431
TRG_DiLeu_BaEn_1	58	63	PF01217	0.444
TRG_DiLeu_BaEn_4	230	236	PF01217	0.643
TRG_DiLeu_BaLyEn_6	31	36	PF01217	0.344
TRG_ENDOCYTIC_2	184	187	PF00928	0.344
TRG_ENDOCYTIC_2	208	211	PF00928	0.452
TRG_ENDOCYTIC_2	32	35	PF00928	0.344
TRG_ENDOCYTIC_2	38	41	PF00928	0.344
TRG_ER_diArg_1	154	156	PF00400	0.460
TRG_ER_diArg_1	172	175	PF00400	0.188
TRG_ER_diArg_1	232	235	PF00400	0.540
TRG_ER_diArg_1	288	290	PF00400	0.561
TRG_Pf-PMV_PEXEL_1	121	126	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	19	23	PF00026	0.439
TRG_Pf-PMV_PEXEL_1	272	276	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	34	39	PF00026	0.228

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I881	Leptomonas seymouri	71%	100%
A0A0S4J6L8	Bodo saltans	31%	78%
A0A1X0NV53	Trypanosomatidae	46%	100%
A0A3S7X590	Leishmania donovani	91%	100%
A4HK51	Leishmania braziliensis	84%	100%
A4I7N7	Leishmania infantum	92%	100%
D0A9T8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
Q4Q5L2	Leishmania major	91%	100%