Probable eukaryotic initiation factor 4A

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase HEL67

Species:

Leishmania mexicana

UniProt:

E9B2G1_LEIMU

TriTrypDb:

LmxM.31.0400

Length:

622

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0010494	cytoplasmic stress granule	5	1
GO:0034399	nuclear periphery	2	1
GO:0035770	ribonucleoprotein granule	3	1
GO:0036464	cytoplasmic ribonucleoprotein granule	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0097165	nuclear stress granule	4	1
GO:0099080	supramolecular complex	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B2G1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2G1

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003724	RNA helicase activity	3	12
GO:0003743	translation initiation factor activity	4	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	12
GO:0008186	ATP-dependent activity, acting on RNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	12
GO:0090079	translation regulator activity, nucleic acid binding	2	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	239	241	PF00675	0.294
CLV_PCSK_KEX2_1	382	384	PF00082	0.294
CLV_PCSK_KEX2_1	405	407	PF00082	0.294
CLV_PCSK_KEX2_1	491	493	PF00082	0.627
CLV_PCSK_PC1ET2_1	382	384	PF00082	0.294
CLV_PCSK_PC1ET2_1	405	407	PF00082	0.294
CLV_PCSK_PC1ET2_1	491	493	PF00082	0.627
CLV_PCSK_SKI1_1	240	244	PF00082	0.286
CLV_PCSK_SKI1_1	349	353	PF00082	0.422
DEG_APCC_DBOX_1	382	390	PF00400	0.494
DEG_Nend_Nbox_1	1	3	PF02207	0.731
DEG_SPOP_SBC_1	363	367	PF00917	0.468
DOC_CDC14_PxL_1	146	154	PF14671	0.434
DOC_CKS1_1	274	279	PF01111	0.494
DOC_CYCLIN_yCln2_LP_2	196	202	PF00134	0.535
DOC_MAPK_DCC_7	457	466	PF00069	0.494
DOC_MAPK_gen_1	382	389	PF00069	0.497
DOC_MAPK_gen_1	432	440	PF00069	0.555
DOC_MAPK_gen_1	488	498	PF00069	0.581
DOC_MAPK_HePTP_8	454	466	PF00069	0.494
DOC_MAPK_MEF2A_6	114	122	PF00069	0.567
DOC_MAPK_MEF2A_6	457	466	PF00069	0.494
DOC_PP1_RVXF_1	395	402	PF00149	0.580
DOC_PP2B_LxvP_1	459	462	PF13499	0.490
DOC_PP4_MxPP_1	325	328	PF00568	0.555
DOC_SPAK_OSR1_1	295	299	PF12202	0.505
DOC_USP7_MATH_1	139	143	PF00917	0.504
DOC_USP7_MATH_1	213	217	PF00917	0.567
DOC_USP7_MATH_1	421	425	PF00917	0.555
DOC_WW_Pin1_4	114	119	PF00397	0.587
DOC_WW_Pin1_4	130	135	PF00397	0.417
DOC_WW_Pin1_4	162	167	PF00397	0.437
DOC_WW_Pin1_4	223	228	PF00397	0.556
DOC_WW_Pin1_4	273	278	PF00397	0.494
LIG_14-3-3_CanoR_1	240	245	PF00244	0.494
LIG_14-3-3_CanoR_1	290	298	PF00244	0.525
LIG_14-3-3_CanoR_1	331	335	PF00244	0.493
LIG_14-3-3_CanoR_1	362	370	PF00244	0.476
LIG_APCC_ABBA_1	233	238	PF00400	0.494
LIG_APCC_ABBA_1	398	403	PF00400	0.494
LIG_APCC_ABBAyCdc20_2	397	403	PF00400	0.580
LIG_BRCT_BRCA1_1	280	284	PF00533	0.599
LIG_BRCT_BRCA1_1	336	340	PF00533	0.494
LIG_BRCT_BRCA1_1	547	551	PF00533	0.775
LIG_BRCT_BRCA1_1	616	620	PF00533	0.739
LIG_BRCT_BRCA1_2	336	342	PF00533	0.580
LIG_Clathr_ClatBox_1	399	403	PF01394	0.484
LIG_FHA_1	115	121	PF00498	0.571
LIG_FHA_1	143	149	PF00498	0.522
LIG_FHA_1	226	232	PF00498	0.493
LIG_FHA_1	365	371	PF00498	0.462
LIG_FHA_2	131	137	PF00498	0.502
LIG_LIR_Apic_2	192	198	PF02991	0.494
LIG_LIR_Gen_1	123	132	PF02991	0.495
LIG_LIR_Gen_1	141	151	PF02991	0.383
LIG_LIR_Gen_1	289	299	PF02991	0.519
LIG_LIR_Nem_3	123	128	PF02991	0.519
LIG_LIR_Nem_3	285	291	PF02991	0.505
LIG_LIR_Nem_3	293	299	PF02991	0.505
LIG_MYND_1	10	14	PF01753	0.571
LIG_Pex14_2	551	555	PF04695	0.731
LIG_PTB_Apo_2	96	103	PF02174	0.736
LIG_PTB_Phospho_1	96	102	PF10480	0.740
LIG_REV1ctd_RIR_1	496	506	PF16727	0.411
LIG_SH2_CRK	161	165	PF00017	0.457
LIG_SH2_CRK	170	174	PF00017	0.494
LIG_SH2_CRK	470	474	PF00017	0.494
LIG_SH2_NCK_1	470	474	PF00017	0.494
LIG_SH2_SRC	195	198	PF00017	0.494
LIG_SH2_SRC	236	239	PF00017	0.555
LIG_SH2_STAP1	336	340	PF00017	0.494
LIG_SH2_STAT3	2	5	PF00017	0.756
LIG_SH2_STAT3	414	417	PF00017	0.580
LIG_SH2_STAT3	44	47	PF00017	0.734
LIG_SH2_STAT5	195	198	PF00017	0.494
LIG_SH2_STAT5	288	291	PF00017	0.498
LIG_SH2_STAT5	410	413	PF00017	0.519
LIG_SH2_STAT5	414	417	PF00017	0.519
LIG_SH2_STAT5	479	482	PF00017	0.494
LIG_SH3_3	221	227	PF00018	0.505
LIG_SH3_3	25	31	PF00018	0.760
LIG_SH3_3	271	277	PF00018	0.494
LIG_SH3_3	315	321	PF00018	0.519
LIG_SH3_4	531	538	PF00018	0.741
LIG_SxIP_EBH_1	413	426	PF03271	0.598
LIG_TRAF2_1	108	111	PF00917	0.577
LIG_TYR_ITSM	287	294	PF00017	0.598
LIG_UBA3_1	386	391	PF00899	0.598
MOD_CDC14_SPxK_1	226	229	PF00782	0.598
MOD_CDK_SPxK_1	223	229	PF00069	0.598
MOD_CDK_SPxK_1	273	279	PF00069	0.494
MOD_CDK_SPxxK_3	162	169	PF00069	0.362
MOD_CK1_1	142	148	PF00069	0.517
MOD_CK1_1	189	195	PF00069	0.491
MOD_CK1_1	211	217	PF00069	0.452
MOD_CK1_1	218	224	PF00069	0.484
MOD_CK2_1	105	111	PF00069	0.651
MOD_CK2_1	362	368	PF00069	0.481
MOD_Cter_Amidation	238	241	PF01082	0.305
MOD_Cter_Amidation	489	492	PF01082	0.503
MOD_GlcNHglycan	188	191	PF01048	0.308
MOD_GlcNHglycan	217	220	PF01048	0.335
MOD_GlcNHglycan	336	339	PF01048	0.294
MOD_GlcNHglycan	442	445	PF01048	0.319
MOD_GlcNHglycan	547	550	PF01048	0.752
MOD_GSK3_1	211	218	PF00069	0.556
MOD_GSK3_1	225	232	PF00069	0.494
MOD_GSK3_1	278	285	PF00069	0.586
MOD_GSK3_1	330	337	PF00069	0.494
MOD_GSK3_1	364	371	PF00069	0.467
MOD_GSK3_1	449	456	PF00069	0.494
MOD_N-GLC_1	176	181	PF02516	0.411
MOD_N-GLC_1	208	213	PF02516	0.224
MOD_N-GLC_1	368	373	PF02516	0.468
MOD_N-GLC_1	517	522	PF02516	0.488
MOD_N-GLC_2	157	159	PF02516	0.539
MOD_NEK2_1	208	213	PF00069	0.437
MOD_NEK2_1	334	339	PF00069	0.494
MOD_NEK2_1	415	420	PF00069	0.598
MOD_NEK2_1	514	519	PF00069	0.454
MOD_NEK2_2	421	426	PF00069	0.555
MOD_PIKK_1	213	219	PF00454	0.586
MOD_PIKK_1	368	374	PF00454	0.446
MOD_PK_1	229	235	PF00069	0.505
MOD_PKA_1	240	246	PF00069	0.494
MOD_PKA_1	491	497	PF00069	0.590
MOD_PKA_2	278	284	PF00069	0.570
MOD_PKA_2	289	295	PF00069	0.487
MOD_PKA_2	330	336	PF00069	0.494
MOD_PKA_2	415	421	PF00069	0.513
MOD_PKA_2	491	497	PF00069	0.590
MOD_PKA_2	514	520	PF00069	0.546
MOD_Plk_1	229	235	PF00069	0.485
MOD_Plk_1	517	523	PF00069	0.585
MOD_Plk_2-3	105	111	PF00069	0.679
MOD_Plk_4	330	336	PF00069	0.486
MOD_Plk_4	494	500	PF00069	0.305
MOD_Plk_4	517	523	PF00069	0.560
MOD_ProDKin_1	114	120	PF00069	0.580
MOD_ProDKin_1	130	136	PF00069	0.420
MOD_ProDKin_1	162	168	PF00069	0.344
MOD_ProDKin_1	223	229	PF00069	0.572
MOD_ProDKin_1	273	279	PF00069	0.494
TRG_DiLeu_BaEn_1	330	335	PF01217	0.580
TRG_DiLeu_BaLyEn_6	509	514	PF01217	0.438
TRG_ENDOCYTIC_2	125	128	PF00928	0.526
TRG_ENDOCYTIC_2	291	294	PF00928	0.505
TRG_ER_diArg_1	158	161	PF00400	0.475
TRG_ER_diArg_1	538	541	PF00400	0.791
TRG_ER_diArg_1	594	597	PF00400	0.713
TRG_Pf-PMV_PEXEL_1	229	234	PF00026	0.284
TRG_Pf-PMV_PEXEL_1	295	300	PF00026	0.319
TRG_Pf-PMV_PEXEL_1	315	319	PF00026	0.294
TRG_Pf-PMV_PEXEL_1	413	417	PF00026	0.380
TRG_Pf-PMV_PEXEL_1	504	508	PF00026	0.416

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7J1	Leptomonas seymouri	31%	69%
A0A0N0P942	Leptomonas seymouri	33%	72%
A0A0N1I5R1	Leptomonas seymouri	23%	78%
A0A0N1I7N1	Leptomonas seymouri	84%	100%
A0A0N1PCW9	Leptomonas seymouri	50%	70%
A0A0S4IKX9	Bodo saltans	25%	82%
A0A0S4IX79	Bodo saltans	30%	85%
A0A0S4J192	Bodo saltans	77%	100%
A0A0S4JDN6	Bodo saltans	53%	75%
A0A0S4KKU4	Bodo saltans	30%	89%
A0A1X0NJH3	Trypanosomatidae	27%	100%
A0A1X0NQS6	Trypanosomatidae	35%	100%
A0A1X0P5C7	Trypanosomatidae	52%	79%
A0A1X0P6S6	Trypanosomatidae	74%	94%
A0A1X0P8K3	Trypanosomatidae	39%	100%
A0A3Q8IC45	Leishmania donovani	29%	100%
A0A3Q8ID91	Leishmania donovani	37%	100%
A0A3Q8IF94	Leishmania donovani	96%	100%
A0A3Q8IG57	Leishmania donovani	26%	79%
A0A3Q8IJ79	Leishmania donovani	51%	68%
A0A3Q8IQY6	Leishmania donovani	39%	100%
A0A3R7KAR1	Trypanosoma rangeli	34%	100%
A0A3R7MLR3	Trypanosoma rangeli	24%	100%
A0A3R7N322	Trypanosoma rangeli	69%	100%
A0A3S5H5X3	Leishmania donovani	40%	100%
A0A3S7WQ33	Leishmania donovani	33%	91%
A0A3S7WR01	Leishmania donovani	24%	80%
A0A3S7X579	Leishmania donovani	28%	100%
A0A3S7XAT8	Leishmania donovani	35%	100%
A0A422MXD2	Trypanosoma rangeli	52%	78%
A0A422N502	Trypanosoma rangeli	38%	100%
A0A422P419	Trypanosoma rangeli	25%	100%
A1C5V3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	37%	100%
A1C6C4	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	41%	100%
A1CH78	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	51%	91%
A1CHL3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	32%	78%
A1CX72	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	36%	78%
A1CXK7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	49%	92%
A1DGZ7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	41%	100%
A1RFB3	Shewanella sp. (strain W3-18-1)	32%	100%
A2QFL3	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	100%
A2QI25	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	51%	92%
A2QIL2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	77%
A3LQ01	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	53%	96%
A3LQ55	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	36%	71%
A4H575	Leishmania braziliensis	33%	72%
A4HC04	Leishmania braziliensis	29%	100%
A4HGR1	Leishmania braziliensis	38%	100%
A4HK20	Leishmania braziliensis	95%	100%
A4HK38	Leishmania braziliensis	27%	100%
A4HMX7	Leishmania braziliensis	51%	72%
A4HP49	Leishmania braziliensis	33%	100%
A4HP82	Leishmania braziliensis	40%	100%
A4HPB9	Leishmania braziliensis	24%	87%
A4HT33	Leishmania infantum	42%	100%
A4HTF8	Leishmania infantum	33%	91%
A4HUC1	Leishmania infantum	22%	80%
A4HZF8	Leishmania infantum	29%	100%
A4I3T6	Leishmania infantum	37%	100%
A4I7K4	Leishmania infantum	96%	100%
A4I7M5	Leishmania infantum	28%	100%
A4IBK1	Leishmania infantum	51%	67%
A4ICF9	Leishmania infantum	26%	100%
A4IDF6	Leishmania infantum	35%	100%
A4IDI7	Leishmania infantum	39%	100%
A4QSS5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	40%	100%
A4RHF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	45%	93%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	92%
A4YB09	Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)	32%	100%
A5A6J2	Pan troglodytes	36%	100%
A5DDF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	35%	72%
A5DF03	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	100%
A5DQS0	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	53%	98%
A5DZE6	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	53%	94%
A6R3L3	Ajellomyces capsulatus (strain NAm1 / WU24)	51%	90%
A6RGE3	Ajellomyces capsulatus (strain NAm1 / WU24)	41%	100%
A6SEH9	Botryotinia fuckeliana (strain B05.10)	53%	91%
A6SFW7	Botryotinia fuckeliana (strain B05.10)	40%	100%
A6ZP47	Saccharomyces cerevisiae (strain YJM789)	51%	100%
A6ZSX1	Saccharomyces cerevisiae (strain YJM789)	35%	100%
A6ZWD3	Saccharomyces cerevisiae (strain YJM789)	49%	100%
A7E449	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	37%	100%
A7EJY3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	54%	92%
A7MXT4	Vibrio campbellii (strain ATCC BAA-1116)	33%	100%
A7TKR8	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	52%	96%
A7TS37	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	34%	100%
A8GZJ0	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	32%	100%
B1KQF6	Shewanella woodyi (strain ATCC 51908 / MS32)	32%	100%
B8CHZ1	Shewanella piezotolerans (strain WP3 / JCM 13877)	32%	100%
C6DHF5	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	32%	100%
C8V8H4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	51%	93%
C9ZUS0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZYS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	81%
C9ZZ43	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	84%
D0A0A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
D0A378	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
D0A872	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
D0PV95	Caenorhabditis elegans	45%	88%
E9AFD4	Leishmania major	51%	67%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AL45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9AM86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	91%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9ASZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9AT30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	88%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9B6I9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	67%
G0SFM2	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	40%	100%
O00571	Homo sapiens	49%	94%
O01836	Caenorhabditis elegans	37%	86%
O13370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	49%	98%
O15523	Homo sapiens	51%	94%
P06634	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	100%
P09052	Drosophila melanogaster	46%	94%
P0CQ74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	54%	98%
P0CQ75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	54%	98%
P16381	Mus musculus	51%	94%
P17844	Homo sapiens	36%	100%
P24346	Xenopus laevis	48%	89%
P24782	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	100%
P24784	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	49%	100%
P34689	Caenorhabditis elegans	39%	82%
P38712	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
Q088J2	Shewanella frigidimarina (strain NCIMB 400)	33%	100%
Q0CL13	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	37%	100%
Q0CLJ6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	47%	92%
Q0CLX0	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	34%	79%
Q0D8N0	Oryza sativa subsp. japonica	34%	100%
Q0DB53	Oryza sativa subsp. japonica	49%	100%
Q0E3X4	Oryza sativa subsp. japonica	37%	99%
Q10202	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	100%
Q10MH8	Oryza sativa subsp. japonica	40%	81%
Q12S35	Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)	33%	100%
Q1DJF0	Coccidioides immitis (strain RS)	47%	94%
Q1DMX8	Coccidioides immitis (strain RS)	35%	76%
Q1DP69	Coccidioides immitis (strain RS)	38%	100%
Q26696	Trypanosoma brucei brucei	39%	100%
Q2H720	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	41%	100%
Q2HBE7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	56%	90%
Q2HEB0	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	35%	88%
Q2R1M8	Oryza sativa subsp. japonica	53%	100%
Q2U070	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	41%	100%
Q2UGK3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	53%	92%
Q2UH00	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	77%
Q3MSQ8	Pelophylax lessonae	44%	86%
Q4I7F9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	34%	86%
Q4I7K4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	54%	92%
Q4IF76	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	40%	100%
Q4JG17	Penaeus vannamei	44%	88%
Q4P733	Ustilago maydis (strain 521 / FGSC 9021)	49%	93%
Q4Q1G8	Leishmania major	25%	89%
Q4Q1K8	Leishmania major	39%	100%
Q4Q1N9	Leishmania major	33%	100%
Q4Q5M6	Leishmania major	28%	100%
Q4Q5P5	Leishmania major	95%	100%
Q4Q858	Leishmania major	38%	100%
Q4QC38	Leishmania major	29%	100%
Q4QIG1	Leishmania major	33%	91%
Q4QIQ9	Leishmania major	42%	100%
Q4R5S7	Macaca fascicularis	47%	86%
Q4R6M5	Macaca fascicularis	38%	100%
Q4WP13	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	49%	92%
Q4WPE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	78%
Q4X195	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	41%	100%
Q501J6	Mus musculus	37%	96%
Q54CE0	Dictyostelium discoideum	39%	79%
Q54QS3	Dictyostelium discoideum	47%	87%
Q54Y81	Dictyostelium discoideum	36%	75%
Q59LU0	Candida albicans (strain SC5314 / ATCC MYA-2876)	41%	100%
Q5A4E2	Candida albicans (strain SC5314 / ATCC MYA-2876)	52%	93%
Q5ADL0	Candida albicans (strain SC5314 / ATCC MYA-2876)	34%	70%
Q5B0J9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	100%
Q5BCU6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	34%	80%
Q5JKF2	Oryza sativa subsp. japonica	42%	79%
Q5N7W4	Oryza sativa subsp. japonica	41%	93%
Q5QMN3	Oryza sativa subsp. japonica	42%	100%
Q5R4I9	Pongo abelii	38%	100%
Q5R7D1	Pongo abelii	39%	66%
Q5RC67	Pongo abelii	38%	76%
Q5RF43	Pongo abelii	52%	95%
Q5T1V6	Homo sapiens	35%	100%
Q5VQL1	Oryza sativa subsp. japonica	40%	88%
Q5W5U4	Bos taurus	45%	85%
Q5Z6G5	Oryza sativa subsp. japonica	36%	100%
Q61496	Mus musculus	46%	89%
Q61656	Mus musculus	37%	100%
Q62095	Mus musculus	49%	95%
Q62167	Mus musculus	48%	94%
Q64060	Rattus norvegicus	46%	87%
Q6BU54	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	52%	99%
Q6C4D4	Yarrowia lipolytica (strain CLIB 122 / E 150)	40%	100%
Q6C9P3	Yarrowia lipolytica (strain CLIB 122 / E 150)	37%	100%
Q6CB69	Yarrowia lipolytica (strain CLIB 122 / E 150)	53%	100%
Q6CIV2	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	40%	100%
Q6CLR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	53%	99%
Q6CT85	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	35%	100%
Q6CZD9	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	33%	100%
Q6FNK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	35%	100%
Q6FP38	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	48%	100%
Q6GVM6	Pan troglodytes	52%	94%
Q6GWX0	Sus scrofa	47%	86%
Q6Z4K6	Oryza sativa subsp. japonica	54%	97%
Q755N4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	38%	100%
Q75B50	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	51%	100%
Q75EW9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
Q75HJ0	Oryza sativa subsp. japonica	55%	98%
Q7MGP7	Vibrio vulnificus (strain YJ016)	34%	100%
Q7RY59	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q7SBC6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	100%
Q7SEL0	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	85%
Q810A7	Mus musculus	39%	67%
Q84W89	Arabidopsis thaliana	53%	98%
Q86XP3	Homo sapiens	39%	66%
Q87KH5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	33%	100%
Q8DDN6	Vibrio vulnificus (strain CMCP6)	34%	100%
Q8LA13	Arabidopsis thaliana	48%	100%
Q8SRB2	Encephalitozoon cuniculi (strain GB-M1)	38%	100%
Q8TFK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	49%	100%
Q91372	Xenopus laevis	46%	89%
Q91VN6	Mus musculus	38%	100%
Q92841	Homo sapiens	36%	85%
Q9BUQ8	Homo sapiens	38%	76%
Q9C718	Arabidopsis thaliana	40%	100%
Q9DBN9	Mus musculus	34%	100%
Q9LU46	Arabidopsis thaliana	37%	100%
Q9LYJ9	Arabidopsis thaliana	40%	96%
Q9M2F9	Arabidopsis thaliana	52%	96%
Q9NQI0	Homo sapiens	47%	86%
Q9NXZ2	Homo sapiens	40%	96%
Q9P6U9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	90%
Q9SZB4	Arabidopsis thaliana	37%	100%
Q9UJV9	Homo sapiens	38%	100%
Q9V3C0	Drosophila melanogaster	38%	100%
Q9VHP0	Drosophila melanogaster	51%	78%
V5BL56	Trypanosoma cruzi	35%	100%
V5BS80	Trypanosoma cruzi	77%	99%