Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B2F7_LEIMU

TriTrypDb:

LmxM.31.0360

Length:

366

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0030990	intraciliary transport particle	2	1
GO:0032991	protein-containing complex	1	1

Expansion

Sequence features

E9B2F7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2F7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	319	323	PF00656	0.778
CLV_NRD_NRD_1	18	20	PF00675	0.475
CLV_NRD_NRD_1	236	238	PF00675	0.612
CLV_NRD_NRD_1	249	251	PF00675	0.554
CLV_PCSK_FUR_1	149	153	PF00082	0.684
CLV_PCSK_FUR_1	16	20	PF00082	0.335
CLV_PCSK_KEX2_1	151	153	PF00082	0.618
CLV_PCSK_KEX2_1	18	20	PF00082	0.455
CLV_PCSK_KEX2_1	249	251	PF00082	0.654
CLV_PCSK_KEX2_1	340	342	PF00082	0.791
CLV_PCSK_PC1ET2_1	151	153	PF00082	0.657
CLV_PCSK_PC1ET2_1	340	342	PF00082	0.791
CLV_PCSK_SKI1_1	152	156	PF00082	0.682
CLV_PCSK_SKI1_1	237	241	PF00082	0.610
CLV_PCSK_SKI1_1	249	253	PF00082	0.600
DEG_APCC_DBOX_1	248	256	PF00400	0.634
DEG_Nend_UBRbox_3	1	3	PF02207	0.665
DOC_ANK_TNKS_1	94	101	PF00023	0.711
DOC_CYCLIN_RxL_1	128	136	PF00134	0.503
DOC_USP7_MATH_1	284	288	PF00917	0.670
DOC_USP7_MATH_1	308	312	PF00917	0.671
DOC_USP7_MATH_1	313	317	PF00917	0.702
DOC_USP7_MATH_1	336	340	PF00917	0.544
DOC_USP7_MATH_1	99	103	PF00917	0.735
DOC_WW_Pin1_4	343	348	PF00397	0.667
LIG_14-3-3_CanoR_1	140	146	PF00244	0.500
LIG_14-3-3_CanoR_1	152	162	PF00244	0.604
LIG_14-3-3_CanoR_1	16	22	PF00244	0.492
LIG_14-3-3_CanoR_1	237	244	PF00244	0.634
LIG_14-3-3_CanoR_1	293	297	PF00244	0.692
LIG_14-3-3_CanoR_1	90	99	PF00244	0.729
LIG_Clathr_ClatBox_1	132	136	PF01394	0.477
LIG_CSL_BTD_1	305	308	PF09270	0.720
LIG_FHA_2	202	208	PF00498	0.545
LIG_FHA_2	230	236	PF00498	0.545
LIG_LIR_Apic_2	294	299	PF02991	0.690
LIG_LIR_Apic_2	60	66	PF02991	0.697
LIG_LIR_LC3C_4	323	328	PF02991	0.684
LIG_NRBOX	128	134	PF00104	0.459
LIG_NRBOX	251	257	PF00104	0.630
LIG_SH2_SRC	296	299	PF00017	0.735
LIG_SH2_STAT3	5	8	PF00017	0.693
LIG_SH2_STAT5	169	172	PF00017	0.715
LIG_SH2_STAT5	87	90	PF00017	0.636
LIG_SH3_3	213	219	PF00018	0.611
LIG_SH3_3	302	308	PF00018	0.683
LIG_SH3_3	58	64	PF00018	0.657
LIG_SUMO_SIM_par_1	130	136	PF11976	0.480
LIG_UBA3_1	132	138	PF00899	0.504
LIG_WRC_WIRS_1	56	61	PF05994	0.661
MOD_CK1_1	17	23	PF00069	0.506
MOD_CK1_1	316	322	PF00069	0.756
MOD_CK1_1	343	349	PF00069	0.707
MOD_CK2_1	180	186	PF00069	0.776
MOD_CK2_1	201	207	PF00069	0.554
MOD_CK2_1	275	281	PF00069	0.741
MOD_GlcNHglycan	155	158	PF01048	0.649
MOD_GlcNHglycan	170	173	PF01048	0.672
MOD_GlcNHglycan	180	183	PF01048	0.724
MOD_GlcNHglycan	329	333	PF01048	0.725
MOD_GlcNHglycan	342	345	PF01048	0.677
MOD_GlcNHglycan	35	38	PF01048	0.658
MOD_GlcNHglycan	50	53	PF01048	0.564
MOD_GSK3_1	316	323	PF00069	0.693
MOD_GSK3_1	336	343	PF00069	0.539
MOD_N-GLC_1	152	157	PF02516	0.721
MOD_N-GLC_1	67	72	PF02516	0.575
MOD_N-GLC_1	90	95	PF02516	0.702
MOD_N-GLC_2	42	44	PF02516	0.595
MOD_N-GLC_2	45	47	PF02516	0.601
MOD_NEK2_1	1	6	PF00069	0.620
MOD_NEK2_1	111	116	PF00069	0.492
MOD_NEK2_1	14	19	PF00069	0.412
MOD_NEK2_1	178	183	PF00069	0.746
MOD_NEK2_1	26	31	PF00069	0.498
MOD_NEK2_1	285	290	PF00069	0.666
MOD_NEK2_1	33	38	PF00069	0.447
MOD_NEK2_1	72	77	PF00069	0.594
MOD_NEK2_2	201	206	PF00069	0.484
MOD_PIKK_1	138	144	PF00454	0.589
MOD_PIKK_1	26	32	PF00454	0.571
MOD_PIKK_1	313	319	PF00454	0.751
MOD_PIKK_1	99	105	PF00454	0.704
MOD_PKA_1	237	243	PF00069	0.622
MOD_PKA_1	340	346	PF00069	0.491
MOD_PKA_2	17	23	PF00069	0.489
MOD_PKA_2	292	298	PF00069	0.676
MOD_PKA_2	340	346	PF00069	0.491
MOD_Plk_1	67	73	PF00069	0.666
MOD_Plk_4	194	200	PF00069	0.575
MOD_ProDKin_1	343	349	PF00069	0.669
MOD_SUMO_rev_2	130	139	PF00179	0.481
MOD_SUMO_rev_2	356	360	PF00179	0.460
TRG_DiLeu_BaLyEn_6	128	133	PF01217	0.481
TRG_ER_diArg_1	16	19	PF00400	0.338
TRG_NES_CRM1_1	125	136	PF08389	0.484
TRG_Pf-PMV_PEXEL_1	131	136	PF00026	0.478
TRG_Pf-PMV_PEXEL_1	250	254	PF00026	0.606

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8J4	Leptomonas seymouri	57%	98%
A0A1X0P6Q1	Trypanosomatidae	36%	86%
A0A3Q8IGR0	Leishmania donovani	89%	100%
A0A3R7RRK4	Trypanosoma rangeli	37%	92%
A4HK16	Leishmania braziliensis	76%	98%
A4I7K0	Leishmania infantum	90%	100%
D0A0A3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
Q4Q5P9	Leishmania major	92%	100%