Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B2D6_LEIMU

TriTrypDb:

LmxM.31.0160

Length:

394

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B2D6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B2D6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	219	223	PF00656	0.597
CLV_C14_Caspase3-7	275	279	PF00656	0.569
CLV_NRD_NRD_1	162	164	PF00675	0.797
CLV_NRD_NRD_1	199	201	PF00675	0.720
CLV_NRD_NRD_1	313	315	PF00675	0.714
CLV_NRD_NRD_1	350	352	PF00675	0.839
CLV_PCSK_FUR_1	197	201	PF00082	0.720
CLV_PCSK_FUR_1	70	74	PF00082	0.665
CLV_PCSK_KEX2_1	162	164	PF00082	0.573
CLV_PCSK_KEX2_1	199	201	PF00082	0.663
CLV_PCSK_KEX2_1	313	315	PF00082	0.714
CLV_PCSK_KEX2_1	346	348	PF00082	0.831
CLV_PCSK_KEX2_1	69	71	PF00082	0.802
CLV_PCSK_KEX2_1	72	74	PF00082	0.753
CLV_PCSK_KEX2_1	80	82	PF00082	0.580
CLV_PCSK_PC1ET2_1	346	348	PF00082	0.831
CLV_PCSK_PC1ET2_1	69	71	PF00082	0.802
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.753
CLV_PCSK_PC1ET2_1	80	82	PF00082	0.580
CLV_PCSK_PC7_1	76	82	PF00082	0.803
CLV_PCSK_SKI1_1	260	264	PF00082	0.471
CLV_PCSK_SKI1_1	337	341	PF00082	0.739
CLV_PCSK_SKI1_1	372	376	PF00082	0.693
CLV_PCSK_SKI1_1	66	70	PF00082	0.743
DEG_Nend_UBRbox_2	1	3	PF02207	0.706
DOC_ANK_TNKS_1	143	150	PF00023	0.740
DOC_MAPK_MEF2A_6	171	179	PF00069	0.727
DOC_PP4_FxxP_1	331	334	PF00568	0.788
DOC_USP7_MATH_1	138	142	PF00917	0.803
DOC_USP7_MATH_1	15	19	PF00917	0.578
DOC_USP7_MATH_1	233	237	PF00917	0.571
DOC_USP7_MATH_1	318	322	PF00917	0.542
DOC_USP7_MATH_1	339	343	PF00917	0.747
DOC_USP7_MATH_1	376	380	PF00917	0.560
DOC_USP7_MATH_1	83	87	PF00917	0.743
DOC_USP7_UBL2_3	234	238	PF12436	0.593
DOC_WW_Pin1_4	306	311	PF00397	0.847
DOC_WW_Pin1_4	56	61	PF00397	0.810
LIG_14-3-3_CanoR_1	183	193	PF00244	0.731
LIG_14-3-3_CanoR_1	84	88	PF00244	0.660
LIG_APCC_ABBA_1	125	130	PF00400	0.533
LIG_BRCT_BRCA1_1	64	68	PF00533	0.574
LIG_FHA_1	254	260	PF00498	0.492
LIG_FHA_1	365	371	PF00498	0.548
LIG_FHA_2	193	199	PF00498	0.655
LIG_FHA_2	273	279	PF00498	0.566
LIG_FHA_2	36	42	PF00498	0.548
LIG_LIR_Gen_1	271	279	PF02991	0.499
LIG_LIR_Nem_3	2	7	PF02991	0.708
LIG_LIR_Nem_3	271	277	PF02991	0.496
LIG_LIR_Nem_3	65	71	PF02991	0.647
LIG_MYND_1	60	64	PF01753	0.762
LIG_SH2_NCK_1	274	278	PF00017	0.779
LIG_SH2_STAT5	274	277	PF00017	0.776
LIG_SH2_STAT5	4	7	PF00017	0.711
LIG_SH3_2	64	69	PF14604	0.715
LIG_SH3_3	105	111	PF00018	0.750
LIG_SH3_3	11	17	PF00018	0.762
LIG_SH3_3	18	24	PF00018	0.699
LIG_SH3_3	205	211	PF00018	0.754
LIG_SH3_3	367	373	PF00018	0.546
LIG_SH3_3	57	63	PF00018	0.671
LIG_SUMO_SIM_par_1	175	180	PF11976	0.797
LIG_TRAF2_1	10	13	PF00917	0.745
LIG_TRAF2_1	279	282	PF00917	0.653
LIG_WRC_WIRS_1	340	345	PF05994	0.821
LIG_WW_3	239	243	PF00397	0.704
MOD_CDK_SPxxK_3	306	313	PF00069	0.849
MOD_CK1_1	169	175	PF00069	0.623
MOD_CK1_1	212	218	PF00069	0.551
MOD_CK1_1	272	278	PF00069	0.775
MOD_CK2_1	155	161	PF00069	0.601
MOD_CK2_1	45	51	PF00069	0.583
MOD_GlcNHglycan	103	106	PF01048	0.770
MOD_GlcNHglycan	139	143	PF01048	0.711
MOD_GlcNHglycan	171	174	PF01048	0.730
MOD_GlcNHglycan	18	21	PF01048	0.768
MOD_GlcNHglycan	212	215	PF01048	0.609
MOD_GlcNHglycan	224	227	PF01048	0.564
MOD_GlcNHglycan	235	238	PF01048	0.627
MOD_GlcNHglycan	251	254	PF01048	0.751
MOD_GlcNHglycan	293	296	PF01048	0.660
MOD_GlcNHglycan	304	307	PF01048	0.711
MOD_GlcNHglycan	326	329	PF01048	0.645
MOD_GlcNHglycan	383	386	PF01048	0.720
MOD_GlcNHglycan	51	54	PF01048	0.686
MOD_GSK3_1	110	117	PF00069	0.796
MOD_GSK3_1	249	256	PF00069	0.598
MOD_GSK3_1	268	275	PF00069	0.761
MOD_GSK3_1	291	298	PF00069	0.808
MOD_GSK3_1	302	309	PF00069	0.664
MOD_GSK3_1	320	327	PF00069	0.680
MOD_GSK3_1	35	42	PF00069	0.607
MOD_GSK3_1	45	52	PF00069	0.691
MOD_GSK3_1	54	61	PF00069	0.646
MOD_LATS_1	99	105	PF00433	0.757
MOD_N-GLC_1	222	227	PF02516	0.810
MOD_N-GLC_1	302	307	PF02516	0.795
MOD_NEK2_1	312	317	PF00069	0.851
MOD_NEK2_1	338	343	PF00069	0.681
MOD_NEK2_1	364	369	PF00069	0.690
MOD_NEK2_2	269	274	PF00069	0.763
MOD_PIKK_1	357	363	PF00454	0.839
MOD_PKA_1	346	352	PF00069	0.553
MOD_PKA_2	244	250	PF00069	0.821
MOD_PKA_2	312	318	PF00069	0.848
MOD_PKA_2	346	352	PF00069	0.574
MOD_PKA_2	35	41	PF00069	0.762
MOD_PKA_2	364	370	PF00069	0.765
MOD_PKA_2	42	48	PF00069	0.684
MOD_PKA_2	83	89	PF00069	0.675
MOD_Plk_1	260	266	PF00069	0.469
MOD_Plk_1	365	371	PF00069	0.547
MOD_Plk_4	123	129	PF00069	0.807
MOD_Plk_4	269	275	PF00069	0.638
MOD_Plk_4	295	301	PF00069	0.824
MOD_Plk_4	320	326	PF00069	0.819
MOD_ProDKin_1	306	312	PF00069	0.848
MOD_ProDKin_1	56	62	PF00069	0.804
MOD_SUMO_rev_2	252	262	PF00179	0.702
MOD_SUMO_rev_2	341	348	PF00179	0.756
TRG_ENDOCYTIC_2	274	277	PF00928	0.496
TRG_ER_diArg_1	189	192	PF00400	0.688
TRG_ER_diArg_1	312	314	PF00400	0.824
TRG_ER_diArg_1	33	36	PF00400	0.754
TRG_NLS_MonoExtC_3	68	73	PF00514	0.664
TRG_NLS_MonoExtN_4	66	73	PF00514	0.728

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICV9	Leishmania donovani	82%	100%
A4HJZ6	Leishmania braziliensis	63%	100%
A4I7H9	Leishmania infantum	81%	100%
Q4Q5S0	Leishmania major	83%	100%