Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B291_LEIMU

TriTrypDb:

LmxM.30.2910

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B291

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B291

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.697
CLV_NRD_NRD_1	107	109	PF00675	0.574
CLV_NRD_NRD_1	215	217	PF00675	0.598
CLV_NRD_NRD_1	246	248	PF00675	0.769
CLV_NRD_NRD_1	92	94	PF00675	0.486
CLV_PCSK_KEX2_1	106	108	PF00082	0.578
CLV_PCSK_KEX2_1	215	217	PF00082	0.598
CLV_PCSK_KEX2_1	246	248	PF00082	0.769
CLV_PCSK_KEX2_1	92	94	PF00082	0.486
CLV_PCSK_SKI1_1	42	46	PF00082	0.453
DEG_APCC_DBOX_1	41	49	PF00400	0.445
DEG_SCF_FBW7_1	143	150	PF00400	0.665
DEG_SPOP_SBC_1	185	189	PF00917	0.627
DOC_USP7_MATH_1	68	72	PF00917	0.489
DOC_WW_Pin1_4	143	148	PF00397	0.643
DOC_WW_Pin1_4	171	176	PF00397	0.674
DOC_WW_Pin1_4	186	191	PF00397	0.665
DOC_WW_Pin1_4	4	9	PF00397	0.649
DOC_WW_Pin1_4	53	58	PF00397	0.594
DOC_WW_Pin1_4	61	66	PF00397	0.571
LIG_14-3-3_CanoR_1	100	106	PF00244	0.559
LIG_14-3-3_CanoR_1	17	26	PF00244	0.453
LIG_14-3-3_CanoR_1	50	58	PF00244	0.535
LIG_14-3-3_CterR_2	246	248	PF00244	0.632
LIG_eIF4E_1	41	47	PF01652	0.445
LIG_FHA_2	123	129	PF00498	0.563
LIG_FHA_2	130	136	PF00498	0.607
LIG_FHA_2	89	95	PF00498	0.507
LIG_MYND_1	143	147	PF01753	0.610
LIG_SH2_STAT5	51	54	PF00017	0.473
LIG_SH3_2	211	216	PF14604	0.597
LIG_SH3_3	205	211	PF00018	0.634
LIG_SUMO_SIM_par_1	181	189	PF11976	0.632
MOD_CDK_SPK_2	143	148	PF00069	0.666
MOD_CDK_SPxK_1	4	10	PF00069	0.646
MOD_CK1_1	171	177	PF00069	0.681
MOD_CK1_1	229	235	PF00069	0.692
MOD_CK1_1	33	39	PF00069	0.445
MOD_CK1_1	56	62	PF00069	0.694
MOD_CK1_1	64	70	PF00069	0.495
MOD_CK2_1	68	74	PF00069	0.649
MOD_CK2_1	88	94	PF00069	0.475
MOD_Cter_Amidation	244	247	PF01082	0.683
MOD_GlcNHglycan	166	169	PF01048	0.667
MOD_GlcNHglycan	19	22	PF01048	0.473
MOD_GlcNHglycan	66	69	PF01048	0.665
MOD_GSK3_1	143	150	PF00069	0.826
MOD_GSK3_1	164	171	PF00069	0.607
MOD_GSK3_1	186	193	PF00069	0.737
MOD_GSK3_1	226	233	PF00069	0.565
MOD_GSK3_1	52	59	PF00069	0.582
MOD_GSK3_1	64	71	PF00069	0.518
MOD_N-GLC_1	185	190	PF02516	0.626
MOD_NEK2_1	184	189	PF00069	0.490
MOD_NEK2_1	52	57	PF00069	0.486
MOD_NEK2_1	85	90	PF00069	0.548
MOD_NEK2_2	101	106	PF00069	0.563
MOD_PIKK_1	237	243	PF00454	0.643
MOD_PKA_2	109	115	PF00069	0.572
MOD_PKA_2	30	36	PF00069	0.444
MOD_ProDKin_1	143	149	PF00069	0.643
MOD_ProDKin_1	171	177	PF00069	0.675
MOD_ProDKin_1	186	192	PF00069	0.667
MOD_ProDKin_1	4	10	PF00069	0.646
MOD_ProDKin_1	53	59	PF00069	0.603
MOD_ProDKin_1	61	67	PF00069	0.567
TRG_ER_diArg_1	105	108	PF00400	0.580
TRG_ER_diArg_1	214	216	PF00400	0.622
TRG_ER_diArg_1	218	221	PF00400	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCN9	Leptomonas seymouri	39%	99%
A0A3Q8IGF1	Leishmania donovani	90%	100%
A4HJT0	Leishmania braziliensis	71%	99%
A4I796	Leishmania infantum	90%	100%
Q4Q5W7	Leishmania major	90%	100%