Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B279_LEIMU

TriTrypDb:

LmxM.30.2800

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B279

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B279

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	51	55	PF00656	0.507
CLV_C14_Caspase3-7	57	61	PF00656	0.495
CLV_C14_Caspase3-7	8	12	PF00656	0.519
CLV_NRD_NRD_1	107	109	PF00675	0.499
CLV_NRD_NRD_1	135	137	PF00675	0.512
CLV_NRD_NRD_1	186	188	PF00675	0.591
CLV_NRD_NRD_1	2	4	PF00675	0.529
CLV_PCSK_FUR_1	105	109	PF00082	0.507
CLV_PCSK_KEX2_1	107	109	PF00082	0.499
CLV_PCSK_KEX2_1	129	131	PF00082	0.480
CLV_PCSK_KEX2_1	2	4	PF00082	0.529
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.461
CLV_PCSK_SKI1_1	107	111	PF00082	0.545
CLV_PCSK_SKI1_1	130	134	PF00082	0.466
CLV_Separin_Metazoa	219	223	PF03568	0.594
DEG_Nend_UBRbox_1	1	4	PF02207	0.536
DEG_SPOP_SBC_1	37	41	PF00917	0.501
DOC_CYCLIN_RxL_1	155	168	PF00134	0.471
DOC_MAPK_gen_1	117	126	PF00069	0.499
DOC_MAPK_gen_1	183	191	PF00069	0.569
DOC_MAPK_HePTP_8	114	126	PF00069	0.462
DOC_MAPK_MEF2A_6	117	126	PF00069	0.456
DOC_PP1_RVXF_1	185	192	PF00149	0.608
DOC_PP1_SILK_1	224	229	PF00149	0.585
DOC_USP7_MATH_1	109	113	PF00917	0.508
DOC_USP7_UBL2_3	129	133	PF12436	0.463
LIG_14-3-3_CanoR_1	107	116	PF00244	0.611
LIG_14-3-3_CanoR_1	228	235	PF00244	0.596
LIG_14-3-3_CanoR_1	43	49	PF00244	0.595
LIG_14-3-3_CanoR_1	72	79	PF00244	0.585
LIG_APCC_ABBA_1	200	205	PF00400	0.673
LIG_APCC_ABBAyCdc20_2	199	205	PF00400	0.454
LIG_FHA_1	32	38	PF00498	0.494
LIG_FHA_2	49	55	PF00498	0.567
LIG_FHA_2	57	63	PF00498	0.652
LIG_LIR_Gen_1	166	175	PF02991	0.624
LIG_LIR_LC3C_4	205	209	PF02991	0.613
LIG_LIR_Nem_3	120	124	PF02991	0.510
LIG_LIR_Nem_3	166	172	PF02991	0.622
LIG_LIR_Nem_3	21	26	PF02991	0.512
LIG_PALB2_WD40_1	18	26	PF16756	0.511
LIG_Pex14_2	18	22	PF04695	0.655
LIG_SH2_PTP2	121	124	PF00017	0.496
LIG_SH2_SRC	258	261	PF00017	0.455
LIG_SH2_STAT5	121	124	PF00017	0.496
LIG_SH2_STAT5	146	149	PF00017	0.627
LIG_SH3_3	215	221	PF00018	0.625
LIG_SUMO_SIM_par_1	122	128	PF11976	0.426
LIG_TRAF2_1	140	143	PF00917	0.491
LIG_TRAF2_1	213	216	PF00917	0.669
LIG_TRAF2_1	96	99	PF00917	0.651
MOD_CK1_1	145	151	PF00069	0.577
MOD_CK1_1	39	45	PF00069	0.771
MOD_CK1_1	48	54	PF00069	0.603
MOD_CK1_1	65	71	PF00069	0.524
MOD_CK1_1	73	79	PF00069	0.562
MOD_CK1_1	90	96	PF00069	0.643
MOD_CK1_1	97	103	PF00069	0.531
MOD_CK2_1	122	128	PF00069	0.608
MOD_CK2_1	227	233	PF00069	0.479
MOD_GlcNHglycan	45	48	PF01048	0.766
MOD_GlcNHglycan	89	92	PF01048	0.684
MOD_GSK3_1	142	149	PF00069	0.566
MOD_GSK3_1	222	229	PF00069	0.559
MOD_GSK3_1	27	34	PF00069	0.607
MOD_GSK3_1	38	45	PF00069	0.800
MOD_GSK3_1	48	55	PF00069	0.535
MOD_GSK3_1	71	78	PF00069	0.681
MOD_GSK3_1	90	97	PF00069	0.672
MOD_N-GLC_1	3	8	PF02516	0.652
MOD_NEK2_1	18	23	PF00069	0.534
MOD_NEK2_1	227	232	PF00069	0.543
MOD_NEK2_1	71	76	PF00069	0.670
MOD_PIKK_1	32	38	PF00454	0.573
MOD_PK_1	222	228	PF00069	0.587
MOD_PKA_1	107	113	PF00069	0.549
MOD_PKA_2	107	113	PF00069	0.549
MOD_PKA_2	227	233	PF00069	0.594
MOD_PKA_2	31	37	PF00069	0.648
MOD_PKA_2	42	48	PF00069	0.585
MOD_PKA_2	71	77	PF00069	0.587
MOD_PKB_1	105	113	PF00069	0.552
MOD_PKB_1	153	161	PF00069	0.482
MOD_Plk_1	62	68	PF00069	0.686
MOD_Plk_2-3	233	239	PF00069	0.435
MOD_Plk_2-3	254	260	PF00069	0.450
MOD_Plk_2-3	94	100	PF00069	0.604
MOD_Plk_4	109	115	PF00069	0.512
MOD_Plk_4	18	24	PF00069	0.600
MOD_Plk_4	222	228	PF00069	0.542
MOD_Plk_4	62	68	PF00069	0.513
TRG_DiLeu_BaEn_3	237	243	PF01217	0.649
TRG_DiLeu_BaEn_4	215	221	PF01217	0.596
TRG_ENDOCYTIC_2	121	124	PF00928	0.496
TRG_ER_diArg_1	1	3	PF00400	0.543
TRG_ER_diArg_1	105	108	PF00400	0.506
TRG_ER_diArg_1	182	185	PF00400	0.606
TRG_NLS_MonoExtN_4	185	191	PF00514	0.600
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.466

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJH6	Leptomonas seymouri	39%	100%
A0A3Q8IF41	Leishmania donovani	82%	100%
A4HJR8	Leishmania braziliensis	54%	100%
E9AHL9	Leishmania infantum	81%	100%
Q4Q5X9	Leishmania major	78%	100%