Acetoin dehydrogenase e3 component-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

acetoin dehydrogenase e3 component-like protein

Species:

Leishmania mexicana

UniProt:

E9B264_LEIMU

TriTrypDb:

LmxM.30.2650

Length:

545

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 31
NetGPI	no	yes: 0, no: 31

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	3
GO:0032991	protein-containing complex	1	3
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0045239	tricarboxylic acid cycle enzyme complex	3	3
GO:0045240	dihydrolipoyl dehydrogenase complex	4	3
GO:0045252	oxoglutarate dehydrogenase complex	4	3
GO:0110165	cellular anatomical entity	1	3
GO:1902494	catalytic complex	2	3
GO:1990204	oxidoreductase complex	3	3
GO:1990234	transferase complex	3	3

Expansion

Sequence features

E9B264

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B264

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	32
GO:0019725	cellular homeostasis	2	32
GO:0042592	homeostatic process	3	32
GO:0045454	cell redox homeostasis	3	32
GO:0050789	regulation of biological process	2	32
GO:0050794	regulation of cellular process	3	32
GO:0065007	biological regulation	1	32
GO:0065008	regulation of biological quality	2	32

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	32
GO:0003824	catalytic activity	1	32
GO:0005488	binding	1	32
GO:0016491	oxidoreductase activity	2	32
GO:0036094	small molecule binding	2	32
GO:0043167	ion binding	2	32
GO:0043168	anion binding	3	32
GO:0050660	flavin adenine dinucleotide binding	4	32
GO:0097159	organic cyclic compound binding	2	32
GO:1901265	nucleoside phosphate binding	3	32
GO:1901363	heterocyclic compound binding	2	32
GO:0004148	dihydrolipoyl dehydrogenase activity	5	12
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3	12
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4	12
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	5
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	5
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	5
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	3
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	3
GO:0019152	acetoin dehydrogenase activity	5	3
GO:0052587	diacetyl reductase ((R)-acetoin forming) activity	6	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	173	175	PF00675	0.291
CLV_NRD_NRD_1	299	301	PF00675	0.289
CLV_NRD_NRD_1	3	5	PF00675	0.537
CLV_NRD_NRD_1	453	455	PF00675	0.383
CLV_PCSK_KEX2_1	152	154	PF00082	0.211
CLV_PCSK_KEX2_1	3	5	PF00082	0.549
CLV_PCSK_KEX2_1	453	455	PF00082	0.370
CLV_PCSK_KEX2_1	48	50	PF00082	0.245
CLV_PCSK_PC1ET2_1	152	154	PF00082	0.211
CLV_PCSK_PC1ET2_1	48	50	PF00082	0.238
CLV_PCSK_SKI1_1	158	162	PF00082	0.326
CLV_PCSK_SKI1_1	300	304	PF00082	0.431
CLV_PCSK_SKI1_1	453	457	PF00082	0.307
CLV_PCSK_SKI1_1	504	508	PF00082	0.322
CLV_PCSK_SKI1_1	519	523	PF00082	0.397
DEG_APCC_DBOX_1	2	10	PF00400	0.645
DEG_Nend_Nbox_1	1	3	PF02207	0.529
DOC_CKS1_1	346	351	PF01111	0.405
DOC_CYCLIN_yCln2_LP_2	507	513	PF00134	0.499
DOC_MAPK_gen_1	20	29	PF00069	0.427
DOC_MAPK_gen_1	219	227	PF00069	0.347
DOC_MAPK_gen_1	331	339	PF00069	0.369
DOC_MAPK_gen_1	82	91	PF00069	0.445
DOC_PP2B_LxvP_1	507	510	PF13499	0.321
DOC_USP7_MATH_1	16	20	PF00917	0.647
DOC_USP7_MATH_1	168	172	PF00917	0.280
DOC_USP7_MATH_1	402	406	PF00917	0.359
DOC_USP7_MATH_1	493	497	PF00917	0.336
DOC_USP7_MATH_1	67	71	PF00917	0.293
DOC_USP7_UBL2_3	440	444	PF12436	0.211
DOC_WW_Pin1_4	126	131	PF00397	0.328
DOC_WW_Pin1_4	345	350	PF00397	0.405
DOC_WW_Pin1_4	524	529	PF00397	0.380
LIG_14-3-3_CanoR_1	108	112	PF00244	0.329
LIG_14-3-3_CanoR_1	138	147	PF00244	0.419
LIG_14-3-3_CanoR_1	158	167	PF00244	0.301
LIG_14-3-3_CanoR_1	184	193	PF00244	0.312
LIG_14-3-3_CanoR_1	3	7	PF00244	0.564
LIG_14-3-3_CanoR_1	300	306	PF00244	0.395
LIG_14-3-3_CanoR_1	401	407	PF00244	0.387
LIG_14-3-3_CanoR_1	424	428	PF00244	0.389
LIG_14-3-3_CanoR_1	488	495	PF00244	0.328
LIG_APCC_ABBA_1	89	94	PF00400	0.237
LIG_BRCT_BRCA1_1	394	398	PF00533	0.419
LIG_BRCT_BRCA1_1	495	499	PF00533	0.287
LIG_FHA_1	297	303	PF00498	0.264
LIG_FHA_1	346	352	PF00498	0.409
LIG_FHA_1	398	404	PF00498	0.372
LIG_FHA_2	270	276	PF00498	0.308
LIG_FHA_2	291	297	PF00498	0.357
LIG_FHA_2	465	471	PF00498	0.322
LIG_FHA_2	525	531	PF00498	0.426
LIG_FHA_2	70	76	PF00498	0.296
LIG_GBD_Chelix_1	242	250	PF00786	0.303
LIG_Integrin_RGD_1	84	86	PF01839	0.205
LIG_LIR_Gen_1	319	325	PF02991	0.237
LIG_LIR_Gen_1	426	435	PF02991	0.328
LIG_LIR_Gen_1	439	448	PF02991	0.264
LIG_LIR_Gen_1	97	107	PF02991	0.289
LIG_LIR_Nem_3	154	160	PF02991	0.305
LIG_LIR_Nem_3	161	167	PF02991	0.302
LIG_LIR_Nem_3	319	323	PF02991	0.237
LIG_LIR_Nem_3	426	430	PF02991	0.350
LIG_LIR_Nem_3	439	445	PF02991	0.236
LIG_LIR_Nem_3	490	495	PF02991	0.254
LIG_LIR_Nem_3	97	102	PF02991	0.278
LIG_LYPXL_yS_3	492	495	PF13949	0.303
LIG_SH2_CRK	320	324	PF00017	0.358
LIG_SH2_NCK_1	427	431	PF00017	0.405
LIG_SH2_SRC	377	380	PF00017	0.438
LIG_SH2_SRC	99	102	PF00017	0.211
LIG_SH2_STAP1	425	429	PF00017	0.351
LIG_SH2_STAT3	264	267	PF00017	0.322
LIG_SH2_STAT5	164	167	PF00017	0.274
LIG_SH2_STAT5	292	295	PF00017	0.312
LIG_SH2_STAT5	377	380	PF00017	0.454
LIG_SH2_STAT5	420	423	PF00017	0.335
LIG_SH2_STAT5	7	10	PF00017	0.697
LIG_SH2_STAT5	99	102	PF00017	0.211
LIG_SH3_3	278	284	PF00018	0.326
LIG_SH3_3	343	349	PF00018	0.350
LIG_SUMO_SIM_anti_2	200	205	PF11976	0.296
LIG_SUMO_SIM_anti_2	223	229	PF11976	0.313
LIG_TRAF2_1	268	271	PF00917	0.361
LIG_TRAF2_1	272	275	PF00917	0.361
LIG_TRAF2_1	498	501	PF00917	0.429
LIG_TYR_ITSM	488	495	PF00017	0.231
LIG_UBA3_1	216	224	PF00899	0.419
LIG_WRC_WIRS_1	302	307	PF05994	0.429
MOD_CK2_1	140	146	PF00069	0.268
MOD_CK2_1	269	275	PF00069	0.307
MOD_CK2_1	362	368	PF00069	0.293
MOD_CK2_1	69	75	PF00069	0.299
MOD_GlcNHglycan	287	290	PF01048	0.367
MOD_GSK3_1	296	303	PF00069	0.348
MOD_GSK3_1	325	332	PF00069	0.344
MOD_N-GLC_1	126	131	PF02516	0.231
MOD_N-GLC_1	326	331	PF02516	0.314
MOD_N-GLC_1	408	413	PF02516	0.324
MOD_N-GLC_1	463	468	PF02516	0.385
MOD_NEK2_1	2	7	PF00069	0.587
MOD_NEK2_1	220	225	PF00069	0.318
MOD_NEK2_1	295	300	PF00069	0.343
MOD_NEK2_1	389	394	PF00069	0.480
MOD_NEK2_1	463	468	PF00069	0.347
MOD_PIKK_1	332	338	PF00454	0.237
MOD_PIKK_1	408	414	PF00454	0.385
MOD_PIKK_1	493	499	PF00454	0.299
MOD_PKA_1	300	306	PF00069	0.405
MOD_PKA_2	107	113	PF00069	0.354
MOD_PKA_2	137	143	PF00069	0.374
MOD_PKA_2	2	8	PF00069	0.574
MOD_PKA_2	296	302	PF00069	0.342
MOD_PKA_2	332	338	PF00069	0.437
MOD_PKA_2	423	429	PF00069	0.399
MOD_PKA_2	487	493	PF00069	0.371
MOD_Plk_1	318	324	PF00069	0.405
MOD_Plk_1	325	331	PF00069	0.344
MOD_Plk_1	463	469	PF00069	0.341
MOD_Plk_1	74	80	PF00069	0.471
MOD_Plk_4	197	203	PF00069	0.303
MOD_Plk_4	212	218	PF00069	0.297
MOD_Plk_4	223	229	PF00069	0.323
MOD_Plk_4	290	296	PF00069	0.303
MOD_Plk_4	464	470	PF00069	0.315
MOD_Plk_4	478	484	PF00069	0.303
MOD_Plk_4	69	75	PF00069	0.287
MOD_ProDKin_1	126	132	PF00069	0.328
MOD_ProDKin_1	345	351	PF00069	0.405
MOD_ProDKin_1	524	530	PF00069	0.386
MOD_SUMO_rev_2	101	107	PF00179	0.357
MOD_SUMO_rev_2	270	278	PF00179	0.421
MOD_SUMO_rev_2	376	386	PF00179	0.338
TRG_ENDOCYTIC_2	164	167	PF00928	0.313
TRG_ENDOCYTIC_2	292	295	PF00928	0.303
TRG_ENDOCYTIC_2	320	323	PF00928	0.280
TRG_ENDOCYTIC_2	427	430	PF00928	0.330
TRG_ENDOCYTIC_2	492	495	PF00928	0.296
TRG_ENDOCYTIC_2	99	102	PF00928	0.364
TRG_ER_diArg_1	2	4	PF00400	0.533
TRG_ER_diArg_1	453	455	PF00400	0.419
TRG_Pf-PMV_PEXEL_1	504	508	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	98	103	PF00026	0.334

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P491	Leptomonas seymouri	27%	100%
A0A0N1HUA4	Leptomonas seymouri	80%	96%
A0A0N1IHT7	Leptomonas seymouri	36%	100%
A0A0N1IIN8	Leptomonas seymouri	35%	100%
A0A0S4J6A3	Bodo saltans	20%	100%
A0A0S4JDA8	Bodo saltans	26%	100%
A0A0S4KLJ6	Bodo saltans	36%	87%
A0A1X0NJ18	Trypanosomatidae	51%	85%
A0A1X0NK15	Trypanosomatidae	44%	93%
A0A1X0NRW2	Trypanosomatidae	26%	100%
A0A1X0NZX1	Trypanosomatidae	39%	100%
A0A3Q8IDT8	Leishmania donovani	37%	100%
A0A3Q8IF30	Leishmania donovani	96%	100%
A0A3Q8ITM5	Leishmania donovani	27%	100%
A0A3R7KY91	Trypanosoma rangeli	27%	100%
A0A3R7NB58	Trypanosoma rangeli	20%	100%
A0A3R7NSH5	Trypanosoma rangeli	39%	100%
A0A3S7X4X4	Leishmania donovani	36%	87%
A0A422NPA5	Trypanosoma rangeli	51%	88%
A0A422NPB5	Trypanosoma rangeli	41%	93%
A1AIE2	Escherichia coli O1:K1 / APEC	24%	100%
A1JI37	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	24%	100%
A1KM51	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	29%	100%
A1U1Y5	Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)	28%	100%
A2TIL1	Callithrix jacchus	25%	100%
A4HIY7	Leishmania braziliensis	40%	98%
A4HJQ2	Leishmania braziliensis	35%	97%
A4HJQ3	Leishmania braziliensis	85%	100%
A4HKX6	Leishmania braziliensis	27%	98%
A4I4P1	Leishmania infantum	37%	100%
A4I769	Leishmania infantum	34%	100%
A4I8F6	Leishmania infantum	27%	100%
A4TRG4	Yersinia pestis (strain Pestoides F)	25%	100%
A4VMU6	Pseudomonas stutzeri (strain A1501)	26%	100%
A4WG49	Enterobacter sp. (strain 638)	26%	100%
A4XSQ1	Pseudomonas mendocina (strain ymp)	24%	100%
A5F4K5	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	27%	100%
A5U665	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	29%	100%
A5W6F5	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	25%	100%
A6TGE6	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	25%	100%
A6V3A6	Pseudomonas aeruginosa (strain PA7)	25%	100%
A6VW16	Marinomonas sp. (strain MWYL1)	26%	100%
A7FD10	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	25%	100%
A7ZUI2	Escherichia coli O139:H28 (strain E24377A / ETEC)	24%	100%
A8A770	Escherichia coli O9:H4 (strain HS)	25%	100%
A8AKW0	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	25%	100%
A8GL77	Serratia proteamaculans (strain 568)	25%	100%
A8MS68	Arabidopsis thaliana	24%	87%
A9N0H2	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	25%	100%
A9R6N5	Yersinia pestis bv. Antiqua (strain Angola)	25%	100%
B0KH90	Pseudomonas putida (strain GB-1)	26%	100%
B1IVB6	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	25%	100%
B1J606	Pseudomonas putida (strain W619)	26%	100%
B1JQ50	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	25%	100%
B1LNS2	Escherichia coli (strain SMS-3-5 / SECEC)	25%	100%
B1XBX3	Escherichia coli (strain K12 / DH10B)	24%	100%
B2JZF3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	25%	100%
B2TWF7	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	24%	100%
B2VGA0	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	25%	100%
B4F1H1	Proteus mirabilis (strain HI4320)	26%	100%
B5BJN6	Salmonella paratyphi A (strain AKU_12601)	25%	100%
B5QXQ7	Salmonella enteritidis PT4 (strain P125109)	25%	100%
B5REZ6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	25%	100%
B5XZ14	Klebsiella pneumoniae (strain 342)	25%	100%
B5Z064	Escherichia coli O157:H7 (strain EC4115 / EHEC)	24%	100%
B6I5I0	Escherichia coli (strain SE11)	24%	100%
B7LA64	Escherichia coli (strain 55989 / EAEC)	24%	100%
B7LUN3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	24%	100%
B7M718	Escherichia coli O8 (strain IAI1)	24%	100%
B7MIA0	Escherichia coli O45:K1 (strain S88 / ExPEC)	24%	100%
B7MR55	Escherichia coli O81 (strain ED1a)	25%	100%
B7NFR2	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	24%	100%
B7NU38	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	24%	100%
B7UNU0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	24%	100%
B7UZU5	Pseudomonas aeruginosa (strain LESB58)	25%	100%
B7VM91	Vibrio atlanticus (strain LGP32)	25%	100%
C0Q478	Salmonella paratyphi C (strain RKS4594)	25%	100%
C1AFH2	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	29%	100%
C1DR10	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	26%	100%
C3K4W1	Pseudomonas fluorescens (strain SBW25)	26%	100%
C3LPZ2	Vibrio cholerae serotype O1 (strain M66-2)	27%	100%
C4K3I8	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	25%	100%
C5A0R1	Escherichia coli (strain K12 / MC4100 / BW2952)	24%	100%
C9ZLC8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZMF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	90%
C9ZWN2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
D0A4H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	100%
D0AAR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D0VWY5	Marichromatium gracile	24%	100%
E9AE44	Leishmania major	38%	97%
E9AHL8	Leishmania infantum	96%	100%
E9ALP1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	94%
E9B263	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B3B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	94%
F4JLP5	Arabidopsis thaliana	25%	96%
G0SB20	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	28%	100%
O00087	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
O04955	Brassica rapa subsp. pekinensis	22%	100%
O05139	Pseudomonas fluorescens	26%	100%
O05940	Rhizobium etli (strain CFN 42 / ATCC 51251)	24%	100%
O08749	Mus musculus	27%	100%
O15770	Plasmodium falciparum (isolate 3D7)	22%	100%
O17953	Caenorhabditis elegans	29%	100%
O18480	Manduca sexta	26%	100%
O34324	Bacillus subtilis (strain 168)	27%	100%
O50286	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	29%	100%
O50311	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	26%	100%
O62768	Bos taurus	23%	100%
O84561	Chlamydia trachomatis (strain D/UW-3/Cx)	26%	100%
O89049	Rattus norvegicus	23%	100%
P00390	Homo sapiens	27%	100%
P00392	Pseudomonas aeruginosa	26%	97%
P06715	Escherichia coli (strain K12)	24%	100%
P08332	Shigella flexneri	27%	97%
P09063	Pseudomonas putida	24%	100%
P09622	Homo sapiens	28%	100%
P09623	Sus scrofa	27%	100%
P09624	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P0A0E4	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	22%	100%
P0A0E5	Staphylococcus aureus	22%	100%
P0A0E6	Staphylococcus aureus (strain Mu50 / ATCC 700699)	27%	100%
P0A0E7	Staphylococcus aureus (strain MW2)	27%	100%
P0A0E8	Staphylococcus aureus	27%	100%
P0A9P0	Escherichia coli (strain K12)	28%	100%
P0A9P1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	28%	100%
P0A9P2	Escherichia coli O157:H7	28%	100%
P0A9P3	Shigella flexneri	28%	100%
P11959	Geobacillus stearothermophilus	28%	100%
P14218	Pseudomonas fluorescens	26%	100%
P16171	Bacillus cereus	23%	86%
P17239	Acidithiobacillus ferrooxidans	26%	100%
P18925	Azotobacter vinelandii	26%	100%
P21880	Bacillus subtilis (strain 168)	26%	100%
P23189	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	22%	100%
P27306	Escherichia coli (strain K12)	24%	100%
P27456	Pisum sativum	21%	99%
P30341	Streptomyces lividans	26%	100%
P30635	Caenorhabditis elegans	21%	100%
P31023	Pisum sativum	28%	100%
P31046	Pseudomonas putida	26%	100%
P31052	Pseudomonas putida	26%	100%
P39051	Trypanosoma brucei brucei	20%	100%
P41921	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P42770	Arabidopsis thaliana	21%	96%
P43783	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	24%	100%
P43784	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	28%	100%
P47513	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	25%	100%
P47791	Mus musculus	26%	100%
P48638	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	25%	100%
P48639	Burkholderia cepacia	24%	100%
P48641	Arabidopsis thaliana	21%	100%
P48642	Oryza sativa subsp. japonica	21%	100%
P49819	Canis lupus familiaris	28%	100%
P50529	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	27%	100%
P50970	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	27%	100%
P52992	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	26%	100%
P54533	Bacillus subtilis (strain 168)	27%	100%
P57112	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
P57303	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	26%	100%
P61076	Plasmodium falciparum (isolate 3D7)	21%	88%
P66005	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	27%	100%
P66007	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	29%	100%
P66008	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	25%	100%
P66009	Salmonella typhi	25%	100%
P70619	Rattus norvegicus	26%	100%
P72740	Synechocystis sp. (strain PCC 6803 / Kazusa)	26%	100%
P75393	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	27%	100%
P77212	Escherichia coli (strain K12)	23%	100%
P78965	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
P80461	Nicotiana tabacum	21%	98%
P85207	Thermus scotoductus (strain ATCC 700910 / SA-01)	26%	100%
P90597	Trypanosoma cruzi	26%	100%
P91938	Drosophila melanogaster	21%	91%
P94188	Alcaligenes sp.	26%	97%
P94702	Enterobacter agglomerans	26%	97%
P95596	Rhodobacter capsulatus	26%	100%
P99084	Staphylococcus aureus (strain N315)	27%	100%
P9WHH2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	26%	100%
P9WHH3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	100%
P9WHH4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	29%	100%
P9WHH5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	29%	100%
P9WHH6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WHH7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
P9WHH8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WHH9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
Q02733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
Q02PF5	Pseudomonas aeruginosa (strain UCBPP-PA14)	25%	100%
Q04829	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	24%	100%
Q04933	Trypanosoma brucei brucei	27%	100%
Q0TA96	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	24%	100%
Q16881	Homo sapiens	22%	84%
Q1CBU5	Yersinia pestis bv. Antiqua (strain Antiqua)	25%	100%
Q1CNP4	Yersinia pestis bv. Antiqua (strain Nepal516)	25%	100%
Q1I7F0	Pseudomonas entomophila (strain L48)	25%	100%
Q1QX78	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	29%	100%
Q1R3U7	Escherichia coli (strain UTI89 / UPEC)	24%	100%
Q25861	Plasmodium falciparum (isolate FCH-5)	21%	100%
Q2NQZ3	Sodalis glossinidius (strain morsitans)	23%	100%
Q2SIP2	Hahella chejuensis (strain KCTC 2396)	27%	100%
Q3K9F5	Pseudomonas fluorescens (strain Pf0-1)	25%	100%
Q41219	Glycine max	29%	100%
Q43154	Spinacia oleracea	22%	100%
Q43621	Pisum sativum	22%	100%
Q48A14	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	25%	100%
Q48KI8	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	25%	100%
Q4KFA6	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	25%	100%
Q4Q4U1	Leishmania major	26%	100%
Q4Q5Z6	Leishmania major	95%	100%
Q4Q5Z7	Leishmania major	35%	100%
Q4ZV77	Pseudomonas syringae pv. syringae (strain B728a)	25%	100%
Q50068	Mycobacterium leprae (strain TN)	25%	100%
Q51772	Pseudomonas fluorescens	26%	99%
Q52109	Acinetobacter calcoaceticus	26%	97%
Q54465	Shewanella putrefaciens	26%	98%
Q54EW8	Dictyostelium discoideum	25%	100%
Q57H91	Salmonella choleraesuis (strain SC-B67)	25%	100%
Q5E212	Aliivibrio fischeri (strain ATCC 700601 / ES114)	25%	100%
Q5HGY8	Staphylococcus aureus (strain COL)	27%	100%
Q5NVA2	Pongo abelii	23%	100%
Q5PK71	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	25%	100%
Q5R4B1	Pongo abelii	27%	100%
Q5UWH2	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	29%	100%
Q5UYG6	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	26%	100%
Q60151	Streptococcus thermophilus	21%	100%
Q60HG3	Macaca fascicularis	27%	100%
Q66G61	Yersinia pseudotuberculosis serotype I (strain IP32953)	25%	100%
Q6BPI1	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	20%	100%
Q6C5H4	Yarrowia lipolytica (strain CLIB 122 / E 150)	23%	100%
Q6CZB1	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	25%	100%
Q6FRV2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	24%	100%
Q6GAB8	Staphylococcus aureus (strain MSSA476)	27%	100%
Q6GHY9	Staphylococcus aureus (strain MRSA252)	27%	100%
Q6HA23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	22%	100%
Q6LLT9	Photobacterium profundum (strain SS9)	24%	100%
Q6P6R2	Rattus norvegicus	27%	100%
Q74ZK4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	26%	100%
Q7MBG9	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	27%	100%
Q7MQ83	Vibrio vulnificus (strain YJ016)	26%	100%
Q811C4	Mesocricetus auratus	28%	100%
Q83MI1	Shigella flexneri	24%	100%
Q873E8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q87KN5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	26%	100%
Q884I6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	25%	100%
Q88KY8	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	25%	100%
Q89AQ8	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	26%	100%
Q8CIZ7	Cricetulus griseus	28%	100%
Q8DD46	Vibrio vulnificus (strain CMCP6)	26%	100%
Q8FB93	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	25%	100%
Q8K9T7	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	28%	100%
Q8KCW2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	28%	100%
Q8NTE1	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	26%	100%
Q8T137	Dictyostelium discoideum	24%	100%
Q8X727	Escherichia coli O157:H7	24%	100%
Q8ZA97	Yersinia pestis	25%	100%
Q93379	Caenorhabditis elegans	24%	100%
Q94655	Plasmodium falciparum (isolate K1 / Thailand)	22%	100%
Q99MD6	Mus musculus	22%	84%
Q9HN74	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	26%	100%
Q9HUY1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
Q9I1L9	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
Q9I3D1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
Q9JLT4	Mus musculus	23%	100%
Q9JMH6	Mus musculus	22%	89%
Q9KPF6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	28%	100%
Q9M5K2	Arabidopsis thaliana	27%	100%
Q9M5K3	Arabidopsis thaliana	26%	100%
Q9MYY8	Sus scrofa	22%	100%
Q9NNW7	Homo sapiens	23%	100%
Q9PJI3	Chlamydia muridarum (strain MoPn / Nigg)	27%	100%
Q9SPB1	Vigna unguiculata	26%	100%
Q9VNT5	Drosophila melanogaster	23%	100%
Q9XBQ9	Azotobacter vinelandii	26%	100%
Q9Z0J5	Rattus norvegicus	22%	100%
Q9Z773	Chlamydia pneumoniae	25%	100%
V5B6P6	Trypanosoma cruzi	41%	99%
V5BB90	Trypanosoma cruzi	52%	99%
V5BDX2	Trypanosoma cruzi	41%	100%
V5BVJ1	Trypanosoma cruzi	26%	100%