Ubiquinol-cytochrome-c reductase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquinol-cytochrome-c reductase-like protein

Species:

Leishmania mexicana

UniProt:

E9B257_LEIMU

TriTrypDb:

LmxM.30.2580

Length:

135

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0005750	mitochondrial respiratory chain complex III	4	3
GO:0032991	protein-containing complex	1	3
GO:0045275	respiratory chain complex III	4	3
GO:0070069	cytochrome complex	3	3
GO:0098796	membrane protein complex	2	3
GO:0098798	mitochondrial protein-containing complex	2	3
GO:0098800	inner mitochondrial membrane protein complex	3	3
GO:0098803	respiratory chain complex	3	3
GO:1902494	catalytic complex	2	3
GO:1902495	transmembrane transporter complex	3	3
GO:1990204	oxidoreductase complex	3	3
GO:1990351	transporter complex	2	3

Expansion

Sequence features

E9B257

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B257

Function

Biological processes
Term	Name	Level	Count
GO:0006091	generation of precursor metabolites and energy	3	3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	7	3
GO:0008152	metabolic process	1	3
GO:0009060	aerobic respiration	6	3
GO:0009987	cellular process	1	3
GO:0015980	energy derivation by oxidation of organic compounds	4	3
GO:0019646	aerobic electron transport chain	6	3
GO:0022900	electron transport chain	4	3
GO:0022904	respiratory electron transport chain	5	3
GO:0044237	cellular metabolic process	2	3
GO:0045333	cellular respiration	5	3

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	41	45	PF00082	0.447
CLV_PCSK_SKI1_1	51	55	PF00082	0.415
DEG_Nend_Nbox_1	1	3	PF02207	0.510
DOC_PP4_FxxP_1	61	64	PF00568	0.452
DOC_USP7_MATH_1	37	41	PF00917	0.448
DOC_USP7_MATH_1	5	9	PF00917	0.699
DOC_USP7_MATH_1	65	69	PF00917	0.470
DOC_WW_Pin1_4	101	106	PF00397	0.309
LIG_14-3-3_CanoR_1	41	50	PF00244	0.446
LIG_14-3-3_CanoR_1	99	104	PF00244	0.309
LIG_FHA_1	27	33	PF00498	0.552
LIG_FHA_1	34	40	PF00498	0.578
LIG_FHA_1	42	48	PF00498	0.656
LIG_LIR_Apic_2	59	64	PF02991	0.490
LIG_MYND_1	128	132	PF01753	0.309
LIG_SH2_CRK	2	6	PF00017	0.530
LIG_SH2_GRB2like	2	5	PF00017	0.533
LIG_SH2_NCK_1	2	6	PF00017	0.530
LIG_SH2_STAT5	115	118	PF00017	0.385
LIG_SH2_STAT5	31	34	PF00017	0.448
LIG_UBA3_1	49	56	PF00899	0.440
MOD_CDC14_SPxK_1	104	107	PF00782	0.309
MOD_CDK_SPxK_1	101	107	PF00069	0.309
MOD_CK1_1	12	18	PF00069	0.467
MOD_CK1_1	3	9	PF00069	0.624
MOD_GlcNHglycan	14	17	PF01048	0.534
MOD_GlcNHglycan	56	59	PF01048	0.433
MOD_GSK3_1	3	10	PF00069	0.628
MOD_GSK3_1	33	40	PF00069	0.460
MOD_GSK3_1	41	48	PF00069	0.465
MOD_N-GLC_2	84	86	PF02516	0.309
MOD_N-GLC_2	94	96	PF02516	0.254
MOD_NEK2_1	54	59	PF00069	0.502
MOD_NEK2_1	9	14	PF00069	0.468
MOD_Plk_4	45	51	PF00069	0.443
MOD_Plk_4	56	62	PF00069	0.412
MOD_Plk_4	9	15	PF00069	0.485
MOD_ProDKin_1	101	107	PF00069	0.309
MOD_SUMO_rev_2	123	130	PF00179	0.309
MOD_SUMO_rev_2	68	75	PF00179	0.423
TRG_ENDOCYTIC_2	115	118	PF00928	0.527
TRG_Pf-PMV_PEXEL_1	41	46	PF00026	0.448
TRG_Pf-PMV_PEXEL_1	51	55	PF00026	0.415

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q4Q603	Leishmania major	73%	100%