Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B242_LEIMU

TriTrypDb:

LmxM.30.2420

Length:

227

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B242

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B242

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	197	201	PF00656	0.424
CLV_NRD_NRD_1	104	106	PF00675	0.409
CLV_NRD_NRD_1	131	133	PF00675	0.446
CLV_PCSK_KEX2_1	104	106	PF00082	0.345
CLV_PCSK_KEX2_1	131	133	PF00082	0.446
CLV_PCSK_SKI1_1	188	192	PF00082	0.346
CLV_PCSK_SKI1_1	50	54	PF00082	0.356
DEG_SPOP_SBC_1	21	25	PF00917	0.471
DOC_USP7_MATH_1	147	151	PF00917	0.619
DOC_USP7_MATH_1	173	177	PF00917	0.483
DOC_USP7_MATH_1	207	211	PF00917	0.445
DOC_WW_Pin1_4	22	27	PF00397	0.636
LIG_14-3-3_CanoR_1	104	108	PF00244	0.452
LIG_14-3-3_CanoR_1	188	193	PF00244	0.388
LIG_CaMK_CASK_1	183	188	PF00069	0.382
LIG_deltaCOP1_diTrp_1	84	89	PF00928	0.417
LIG_FHA_1	104	110	PF00498	0.348
LIG_FHA_1	47	53	PF00498	0.392
LIG_FHA_2	189	195	PF00498	0.393
LIG_FHA_2	203	209	PF00498	0.428
LIG_FHA_2	6	12	PF00498	0.633
LIG_LIR_Gen_1	119	129	PF02991	0.416
LIG_LIR_Gen_1	175	184	PF02991	0.412
LIG_LIR_Nem_3	119	124	PF02991	0.387
LIG_LIR_Nem_3	17	21	PF02991	0.614
LIG_LIR_Nem_3	175	180	PF02991	0.439
LIG_LIR_Nem_3	84	89	PF02991	0.537
LIG_MYND_1	2	6	PF01753	0.604
LIG_Pex14_2	121	125	PF04695	0.595
LIG_REV1ctd_RIR_1	118	127	PF16727	0.513
LIG_SH2_CRK	216	220	PF00017	0.413
LIG_SH2_STAT5	177	180	PF00017	0.281
LIG_SH2_STAT5	62	65	PF00017	0.410
LIG_SH3_3	167	173	PF00018	0.491
LIG_SH3_3	23	29	PF00018	0.624
LIG_SUMO_SIM_par_1	49	56	PF11976	0.370
LIG_WRC_WIRS_1	177	182	PF05994	0.285
MOD_CK1_1	176	182	PF00069	0.304
MOD_CK1_1	22	28	PF00069	0.525
MOD_CK2_1	202	208	PF00069	0.359
MOD_CK2_1	5	11	PF00069	0.609
MOD_CK2_1	90	96	PF00069	0.329
MOD_GlcNHglycan	127	130	PF01048	0.528
MOD_GlcNHglycan	147	150	PF01048	0.687
MOD_GSK3_1	172	179	PF00069	0.440
MOD_GSK3_1	42	49	PF00069	0.466
MOD_LATS_1	48	54	PF00433	0.421
MOD_NEK2_1	125	130	PF00069	0.454
MOD_NEK2_1	142	147	PF00069	0.445
MOD_NEK2_1	202	207	PF00069	0.547
MOD_NEK2_1	219	224	PF00069	0.367
MOD_NEK2_1	46	51	PF00069	0.522
MOD_NEK2_1	61	66	PF00069	0.321
MOD_PIKK_1	114	120	PF00454	0.428
MOD_PK_1	79	85	PF00069	0.388
MOD_PKA_2	103	109	PF00069	0.364
MOD_PKA_2	125	131	PF00069	0.584
MOD_PKA_2	202	208	PF00069	0.363
MOD_Plk_1	166	172	PF00069	0.527
MOD_Plk_1	207	213	PF00069	0.420
MOD_Plk_1	42	48	PF00069	0.464
MOD_Plk_4	116	122	PF00069	0.533
MOD_Plk_4	166	172	PF00069	0.527
MOD_Plk_4	173	179	PF00069	0.399
MOD_Plk_4	208	214	PF00069	0.367
MOD_Plk_4	42	48	PF00069	0.402
MOD_ProDKin_1	22	28	PF00069	0.627
TRG_ENDOCYTIC_2	177	180	PF00928	0.540
TRG_ENDOCYTIC_2	216	219	PF00928	0.507
TRG_NES_CRM1_1	183	194	PF08389	0.299
TRG_Pf-PMV_PEXEL_1	50	55	PF00026	0.416

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6W0	Leptomonas seymouri	30%	100%
A0A0N1ILD5	Leptomonas seymouri	42%	80%
A0A3S7X4T4	Leishmania donovani	84%	100%
A4HJM6	Leishmania braziliensis	46%	98%
A4HJM7	Leishmania braziliensis	27%	100%
A4I748	Leishmania infantum	84%	100%
Q4Q619	Leishmania major	77%	100%