Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B241_LEIMU

TriTrypDb:

LmxM.30.2410

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B241

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B241

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	2	6	PF00656	0.505
CLV_PCSK_KEX2_1	94	96	PF00082	0.692
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.642
DEG_SCF_FBW7_1	31	36	PF00400	0.508
DEG_SPOP_SBC_1	125	129	PF00917	0.641
DEG_SPOP_SBC_1	136	140	PF00917	0.521
DOC_CYCLIN_yClb3_PxF_3	83	89	PF00134	0.637
DOC_CYCLIN_yCln2_LP_2	78	84	PF00134	0.683
DOC_PP2B_LxvP_1	42	45	PF13499	0.620
DOC_PP4_FxxP_1	23	26	PF00568	0.596
DOC_USP7_MATH_1	125	129	PF00917	0.743
DOC_USP7_MATH_1	132	136	PF00917	0.476
DOC_USP7_MATH_1	153	157	PF00917	0.736
DOC_USP7_MATH_1	33	37	PF00917	0.528
DOC_USP7_MATH_1	52	56	PF00917	0.680
DOC_WW_Pin1_4	22	27	PF00397	0.485
DOC_WW_Pin1_4	29	34	PF00397	0.492
DOC_WW_Pin1_4	70	75	PF00397	0.634
LIG_BIR_II_1	1	5	PF00653	0.692
LIG_FHA_1	103	109	PF00498	0.538
LIG_FHA_1	118	124	PF00498	0.631
LIG_FHA_1	125	131	PF00498	0.588
LIG_FHA_1	136	142	PF00498	0.688
LIG_LIR_Gen_1	140	151	PF02991	0.594
LIG_LIR_Gen_1	54	60	PF02991	0.566
LIG_LIR_Nem_3	54	59	PF02991	0.569
LIG_PDZ_Class_2	198	203	PF00595	0.572
LIG_SH3_3	160	166	PF00018	0.466
LIG_SH3_3	42	48	PF00018	0.776
LIG_SH3_3	78	84	PF00018	0.633
LIG_SH3_CIN85_PxpxPR_1	162	167	PF14604	0.458
LIG_WRC_WIRS_1	53	58	PF05994	0.571
LIG_WW_3	73	77	PF00397	0.678
MOD_CDC14_SPxK_1	73	76	PF00782	0.675
MOD_CDK_SPxK_1	70	76	PF00069	0.683
MOD_CK1_1	107	113	PF00069	0.654
MOD_CK1_1	124	130	PF00069	0.741
MOD_CK1_1	135	141	PF00069	0.639
MOD_CK1_1	55	61	PF00069	0.725
MOD_GlcNHglycan	123	126	PF01048	0.779
MOD_GlcNHglycan	35	38	PF01048	0.571
MOD_GlcNHglycan	49	52	PF01048	0.647
MOD_GlcNHglycan	89	92	PF01048	0.621
MOD_GlcNHglycan	97	100	PF01048	0.539
MOD_GSK3_1	104	111	PF00069	0.610
MOD_GSK3_1	117	124	PF00069	0.649
MOD_GSK3_1	132	139	PF00069	0.610
MOD_GSK3_1	29	36	PF00069	0.538
MOD_GSK3_1	47	54	PF00069	0.673
MOD_GSK3_1	55	62	PF00069	0.733
MOD_GSK3_1	6	13	PF00069	0.668
MOD_NEK2_1	10	15	PF00069	0.692
MOD_NEK2_1	102	107	PF00069	0.691
MOD_NEK2_1	108	113	PF00069	0.730
MOD_NEK2_1	121	126	PF00069	0.606
MOD_NEK2_1	59	64	PF00069	0.592
MOD_NEK2_2	52	57	PF00069	0.617
MOD_PIKK_1	82	88	PF00454	0.621
MOD_Plk_1	116	122	PF00069	0.643
MOD_Plk_4	104	110	PF00069	0.664
MOD_ProDKin_1	22	28	PF00069	0.485
MOD_ProDKin_1	29	35	PF00069	0.496
MOD_ProDKin_1	70	76	PF00069	0.635
TRG_DiLeu_BaEn_1	104	109	PF01217	0.663

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4V8	Leishmania donovani	85%	100%
A4HJM5	Leishmania braziliensis	62%	99%
A4I747	Leishmania infantum	84%	100%