LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B225_LEIMU
TriTrypDb:
LmxM.30.2240
Length:
152

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
Term Name Level Count
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4

Expansion

Sequence features

E9B225
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B225

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 144 148 PF00656 0.631
CLV_NRD_NRD_1 75 77 PF00675 0.373
CLV_PCSK_KEX2_1 47 49 PF00082 0.427
CLV_PCSK_PC1ET2_1 47 49 PF00082 0.427
CLV_PCSK_SKI1_1 47 51 PF00082 0.424
DOC_CDC14_PxL_1 80 88 PF14671 0.607
DOC_CYCLIN_yCln2_LP_2 14 20 PF00134 0.389
DOC_CYCLIN_yCln2_LP_2 22 28 PF00134 0.313
DOC_PP2B_LxvP_1 14 17 PF13499 0.389
DOC_PP2B_LxvP_1 22 25 PF13499 0.313
DOC_USP7_MATH_1 108 112 PF00917 0.758
DOC_USP7_UBL2_3 77 81 PF12436 0.588
DOC_WW_Pin1_4 96 101 PF00397 0.800
LIG_14-3-3_CanoR_1 112 119 PF00244 0.669
LIG_FHA_1 6 12 PF00498 0.414
LIG_FHA_2 5 11 PF00498 0.491
LIG_LIR_Apic_2 117 122 PF02991 0.635
LIG_SH2_CRK 33 37 PF00017 0.608
LIG_SH2_STAP1 45 49 PF00017 0.684
LIG_SH2_STAT5 12 15 PF00017 0.389
LIG_UBA3_1 49 55 PF00899 0.562
MOD_CDC14_SPxK_1 99 102 PF00782 0.761
MOD_CDK_SPxK_1 96 102 PF00069 0.806
MOD_CK1_1 111 117 PF00069 0.729
MOD_CK1_1 126 132 PF00069 0.621
MOD_CK1_1 4 10 PF00069 0.529
MOD_CK2_1 136 142 PF00069 0.716
MOD_GlcNHglycan 125 128 PF01048 0.593
MOD_GSK3_1 1 8 PF00069 0.506
MOD_GSK3_1 106 113 PF00069 0.676
MOD_GSK3_1 136 143 PF00069 0.602
MOD_GSK3_1 92 99 PF00069 0.800
MOD_PKA_2 111 117 PF00069 0.758
MOD_PKA_2 120 126 PF00069 0.677
MOD_Plk_1 136 142 PF00069 0.810
MOD_Plk_2-3 136 142 PF00069 0.716
MOD_Plk_2-3 145 151 PF00069 0.718
MOD_Plk_2-3 85 91 PF00069 0.733
MOD_Plk_4 129 135 PF00069 0.739
MOD_Plk_4 136 142 PF00069 0.710
MOD_ProDKin_1 96 102 PF00069 0.802
TRG_DiLeu_BaEn_2 45 51 PF01217 0.560
TRG_ENDOCYTIC_2 33 36 PF00928 0.611
TRG_ER_diArg_1 56 59 PF00400 0.638
TRG_Pf-PMV_PEXEL_1 81 85 PF00026 0.466

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IGB0 Leishmania donovani 79% 100%
A4I707 Leishmania infantum 79% 100%
Q4Q637 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS