Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B220_LEIMU

TriTrypDb:

LmxM.30.2195

Length:

579

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B220

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B220

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	257	261	PF00656	0.513
CLV_C14_Caspase3-7	505	509	PF00656	0.548
CLV_C14_Caspase3-7	77	81	PF00656	0.580
CLV_NRD_NRD_1	548	550	PF00675	0.628
CLV_NRD_NRD_1	553	555	PF00675	0.628
CLV_PCSK_KEX2_1	279	281	PF00082	0.551
CLV_PCSK_KEX2_1	500	502	PF00082	0.638
CLV_PCSK_KEX2_1	552	554	PF00082	0.625
CLV_PCSK_PC1ET2_1	279	281	PF00082	0.551
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.638
CLV_PCSK_PC7_1	549	555	PF00082	0.626
CLV_PCSK_SKI1_1	199	203	PF00082	0.613
CLV_PCSK_SKI1_1	45	49	PF00082	0.586
CLV_PCSK_SKI1_1	554	558	PF00082	0.631
CLV_PCSK_SKI1_1	574	578	PF00082	0.469
CLV_Separin_Fungi	64	70	PF03568	0.525
DEG_SCF_FBW7_1	344	350	PF00400	0.630
DEG_SCF_FBW7_1	569	575	PF00400	0.519
DEG_SPOP_SBC_1	377	381	PF00917	0.532
DEG_SPOP_SBC_1	74	78	PF00917	0.526
DOC_CKS1_1	289	294	PF01111	0.543
DOC_CKS1_1	323	328	PF01111	0.548
DOC_CKS1_1	344	349	PF01111	0.632
DOC_CKS1_1	408	413	PF01111	0.528
DOC_CKS1_1	569	574	PF01111	0.518
DOC_CKS1_1	7	12	PF01111	0.588
DOC_CYCLIN_RxL_1	39	52	PF00134	0.584
DOC_CYCLIN_yCln2_LP_2	47	53	PF00134	0.511
DOC_MAPK_gen_1	15	23	PF00069	0.607
DOC_MAPK_gen_1	198	207	PF00069	0.585
DOC_MAPK_gen_1	549	558	PF00069	0.627
DOC_PP1_RVXF_1	251	257	PF00149	0.502
DOC_PP2B_LxvP_1	159	162	PF13499	0.540
DOC_PP4_FxxP_1	408	411	PF00568	0.532
DOC_PP4_FxxP_1	477	480	PF00568	0.528
DOC_USP7_MATH_1	175	179	PF00917	0.681
DOC_USP7_MATH_1	201	205	PF00917	0.666
DOC_USP7_MATH_1	210	214	PF00917	0.558
DOC_USP7_MATH_1	219	223	PF00917	0.474
DOC_USP7_MATH_1	22	26	PF00917	0.593
DOC_USP7_MATH_1	239	243	PF00917	0.524
DOC_USP7_MATH_1	28	32	PF00917	0.594
DOC_USP7_MATH_1	295	299	PF00917	0.680
DOC_USP7_MATH_1	347	351	PF00917	0.704
DOC_USP7_MATH_1	35	39	PF00917	0.514
DOC_USP7_MATH_1	370	374	PF00917	0.637
DOC_USP7_MATH_1	377	381	PF00917	0.581
DOC_USP7_MATH_1	480	484	PF00917	0.627
DOC_USP7_MATH_1	57	61	PF00917	0.596
DOC_USP7_MATH_1	74	78	PF00917	0.636
DOC_USP7_MATH_1	92	96	PF00917	0.584
DOC_USP7_UBL2_3	198	202	PF12436	0.573
DOC_USP7_UBL2_3	570	574	PF12436	0.639
DOC_WW_Pin1_4	157	162	PF00397	0.713
DOC_WW_Pin1_4	244	249	PF00397	0.628
DOC_WW_Pin1_4	288	293	PF00397	0.692
DOC_WW_Pin1_4	319	324	PF00397	0.607
DOC_WW_Pin1_4	334	339	PF00397	0.606
DOC_WW_Pin1_4	343	348	PF00397	0.567
DOC_WW_Pin1_4	357	362	PF00397	0.517
DOC_WW_Pin1_4	371	376	PF00397	0.672
DOC_WW_Pin1_4	407	412	PF00397	0.627
DOC_WW_Pin1_4	53	58	PF00397	0.665
DOC_WW_Pin1_4	568	573	PF00397	0.580
DOC_WW_Pin1_4	6	11	PF00397	0.590
DOC_WW_Pin1_4	70	75	PF00397	0.707
LIG_14-3-3_CanoR_1	180	186	PF00244	0.616
LIG_14-3-3_CanoR_1	218	222	PF00244	0.610
LIG_14-3-3_CanoR_1	240	248	PF00244	0.535
LIG_14-3-3_CanoR_1	255	259	PF00244	0.488
LIG_14-3-3_CanoR_1	286	292	PF00244	0.568
LIG_14-3-3_CanoR_1	366	370	PF00244	0.638
LIG_14-3-3_CanoR_1	49	54	PF00244	0.600
LIG_14-3-3_CanoR_1	552	557	PF00244	0.629
LIG_14-3-3_CanoR_1	58	62	PF00244	0.598
LIG_AP2alpha_2	454	456	PF02296	0.504
LIG_BIR_III_2	141	145	PF00653	0.520
LIG_BRCT_BRCA1_1	358	362	PF00533	0.692
LIG_BRCT_BRCA1_1	473	477	PF00533	0.518
LIG_CSL_BTD_1	71	74	PF09270	0.607
LIG_CtBP_PxDLS_1	564	568	PF00389	0.516
LIG_FHA_1	154	160	PF00498	0.558
LIG_FHA_1	536	542	PF00498	0.530
LIG_FHA_1	553	559	PF00498	0.627
LIG_FHA_1	98	104	PF00498	0.544
LIG_FHA_2	149	155	PF00498	0.639
LIG_FHA_2	382	388	PF00498	0.609
LIG_LIR_Apic_2	405	411	PF02991	0.529
LIG_LIR_Apic_2	474	480	PF02991	0.523
LIG_LIR_Apic_2	52	57	PF02991	0.588
LIG_LIR_Gen_1	401	412	PF02991	0.520
LIG_LIR_Gen_1	492	502	PF02991	0.538
LIG_LIR_Nem_3	118	123	PF02991	0.612
LIG_LIR_Nem_3	401	407	PF02991	0.513
LIG_LIR_Nem_3	445	449	PF02991	0.539
LIG_LIR_Nem_3	492	498	PF02991	0.537
LIG_MAD2	557	565	PF02301	0.586
LIG_Pex14_2	389	393	PF04695	0.520
LIG_Pex14_2	404	408	PF04695	0.525
LIG_SH2_CRK	54	58	PF00017	0.593
LIG_SH2_PTP2	495	498	PF00017	0.639
LIG_SH2_SRC	145	148	PF00017	0.533
LIG_SH2_SRC	447	450	PF00017	0.613
LIG_SH2_STAP1	136	140	PF00017	0.617
LIG_SH2_STAP1	171	175	PF00017	0.544
LIG_SH2_STAP1	311	315	PF00017	0.592
LIG_SH2_STAP1	444	448	PF00017	0.608
LIG_SH2_STAP1	61	65	PF00017	0.527
LIG_SH2_STAP1	99	103	PF00017	0.547
LIG_SH2_STAT3	434	437	PF00017	0.529
LIG_SH2_STAT3	99	102	PF00017	0.548
LIG_SH2_STAT5	434	437	PF00017	0.626
LIG_SH2_STAT5	495	498	PF00017	0.639
LIG_SH2_STAT5	99	102	PF00017	0.723
LIG_SH3_2	248	253	PF14604	0.602
LIG_SH3_2	323	328	PF14604	0.548
LIG_SH3_3	137	143	PF00018	0.655
LIG_SH3_3	163	169	PF00018	0.738
LIG_SH3_3	204	210	PF00018	0.602
LIG_SH3_3	227	233	PF00018	0.626
LIG_SH3_3	245	251	PF00018	0.792
LIG_SH3_3	286	292	PF00018	0.548
LIG_SH3_3	320	326	PF00018	0.696
LIG_TRAF2_1	110	113	PF00917	0.625
LIG_TRAF2_1	468	471	PF00917	0.620
LIG_WRC_WIRS_1	404	409	PF05994	0.528
LIG_WRC_WIRS_1	443	448	PF05994	0.606
LIG_WW_3	180	184	PF00397	0.618
MOD_CDK_SPK_2	334	339	PF00069	0.645
MOD_CDK_SPK_2	53	58	PF00069	0.516
MOD_CDK_SPxK_1	322	328	PF00069	0.545
MOD_CDK_SPxK_1	568	574	PF00069	0.517
MOD_CDK_SPxxK_3	334	341	PF00069	0.637
MOD_CDK_SPxxK_3	407	414	PF00069	0.530
MOD_CK1_1	105	111	PF00069	0.560
MOD_CK1_1	124	130	PF00069	0.505
MOD_CK1_1	220	226	PF00069	0.608
MOD_CK1_1	242	248	PF00069	0.534
MOD_CK1_1	331	337	PF00069	0.680
MOD_CK1_1	356	362	PF00069	0.697
MOD_CK1_1	365	371	PF00069	0.646
MOD_CK1_1	373	379	PF00069	0.633
MOD_CK1_1	381	387	PF00069	0.564
MOD_CK1_1	396	402	PF00069	0.611
MOD_CK1_1	429	435	PF00069	0.614
MOD_CK1_1	483	489	PF00069	0.574
MOD_CK1_1	491	497	PF00069	0.552
MOD_CK1_1	524	530	PF00069	0.602
MOD_CK1_1	56	62	PF00069	0.650
MOD_CK1_1	6	12	PF00069	0.589
MOD_CK1_1	73	79	PF00069	0.593
MOD_CK2_1	124	130	PF00069	0.680
MOD_CK2_1	148	154	PF00069	0.658
MOD_CK2_1	240	246	PF00069	0.540
MOD_CK2_1	376	382	PF00069	0.699
MOD_CK2_1	464	470	PF00069	0.629
MOD_GlcNHglycan	107	110	PF01048	0.615
MOD_GlcNHglycan	177	180	PF01048	0.569
MOD_GlcNHglycan	212	215	PF01048	0.679
MOD_GlcNHglycan	233	236	PF01048	0.654
MOD_GlcNHglycan	330	333	PF01048	0.707
MOD_GlcNHglycan	355	358	PF01048	0.764
MOD_GlcNHglycan	367	370	PF01048	0.783
MOD_GlcNHglycan	428	431	PF01048	0.636
MOD_GlcNHglycan	466	469	PF01048	0.674
MOD_GlcNHglycan	527	530	PF01048	0.674
MOD_GSK3_1	121	128	PF00069	0.575
MOD_GSK3_1	132	139	PF00069	0.490
MOD_GSK3_1	153	160	PF00069	0.588
MOD_GSK3_1	183	190	PF00069	0.662
MOD_GSK3_1	24	31	PF00069	0.613
MOD_GSK3_1	240	247	PF00069	0.776
MOD_GSK3_1	287	294	PF00069	0.632
MOD_GSK3_1	324	331	PF00069	0.669
MOD_GSK3_1	343	350	PF00069	0.652
MOD_GSK3_1	353	360	PF00069	0.694
MOD_GSK3_1	371	378	PF00069	0.612
MOD_GSK3_1	381	388	PF00069	0.589
MOD_GSK3_1	393	400	PF00069	0.722
MOD_GSK3_1	403	410	PF00069	0.517
MOD_GSK3_1	422	429	PF00069	0.672
MOD_GSK3_1	460	467	PF00069	0.705
MOD_GSK3_1	471	478	PF00069	0.584
MOD_GSK3_1	479	486	PF00069	0.583
MOD_GSK3_1	49	56	PF00069	0.757
MOD_GSK3_1	5	12	PF00069	0.705
MOD_GSK3_1	521	528	PF00069	0.604
MOD_GSK3_1	568	575	PF00069	0.518
MOD_GSK3_1	57	64	PF00069	0.577
MOD_GSK3_1	70	77	PF00069	0.726
MOD_GSK3_1	93	100	PF00069	0.618
MOD_N-GLC_1	132	137	PF02516	0.598
MOD_N-GLC_1	426	431	PF02516	0.537
MOD_N-GLC_1	86	91	PF02516	0.531
MOD_NEK2_1	254	259	PF00069	0.574
MOD_NEK2_1	351	356	PF00069	0.574
MOD_NEK2_1	362	367	PF00069	0.615
MOD_NEK2_1	393	398	PF00069	0.538
MOD_NEK2_1	5	10	PF00069	0.590
MOD_NEK2_2	442	447	PF00069	0.603
MOD_NMyristoyl	1	7	PF02799	0.589
MOD_PIKK_1	332	338	PF00454	0.549
MOD_PIKK_1	399	405	PF00454	0.502
MOD_PIKK_1	429	435	PF00454	0.536
MOD_PK_1	125	131	PF00069	0.508
MOD_PK_1	187	193	PF00069	0.581
MOD_PKA_1	279	285	PF00069	0.541
MOD_PKA_1	552	558	PF00069	0.795
MOD_PKA_2	217	223	PF00069	0.685
MOD_PKA_2	239	245	PF00069	0.536
MOD_PKA_2	254	260	PF00069	0.527
MOD_PKA_2	269	275	PF00069	0.595
MOD_PKA_2	279	285	PF00069	0.570
MOD_PKA_2	365	371	PF00069	0.639
MOD_PKA_2	552	558	PF00069	0.629
MOD_PKA_2	57	63	PF00069	0.603
MOD_PKA_2	78	84	PF00069	0.548
MOD_Plk_1	112	118	PF00069	0.524
MOD_Plk_1	132	138	PF00069	0.599
MOD_Plk_1	303	309	PF00069	0.561
MOD_Plk_1	460	466	PF00069	0.542
MOD_Plk_1	491	497	PF00069	0.532
MOD_Plk_1	535	541	PF00069	0.527
MOD_Plk_2-3	112	118	PF00069	0.616
MOD_Plk_4	154	160	PF00069	0.549
MOD_Plk_4	347	353	PF00069	0.626
MOD_Plk_4	403	409	PF00069	0.525
MOD_Plk_4	442	448	PF00069	0.603
MOD_Plk_4	460	466	PF00069	0.554
MOD_Plk_4	49	55	PF00069	0.589
MOD_Plk_4	491	497	PF00069	0.532
MOD_Plk_4	572	578	PF00069	0.513
MOD_Plk_4	78	84	PF00069	0.603
MOD_ProDKin_1	157	163	PF00069	0.711
MOD_ProDKin_1	244	250	PF00069	0.626
MOD_ProDKin_1	288	294	PF00069	0.692
MOD_ProDKin_1	319	325	PF00069	0.608
MOD_ProDKin_1	334	340	PF00069	0.606
MOD_ProDKin_1	343	349	PF00069	0.564
MOD_ProDKin_1	357	363	PF00069	0.518
MOD_ProDKin_1	371	377	PF00069	0.666
MOD_ProDKin_1	407	413	PF00069	0.626
MOD_ProDKin_1	53	59	PF00069	0.665
MOD_ProDKin_1	568	574	PF00069	0.580
MOD_ProDKin_1	6	12	PF00069	0.589
MOD_ProDKin_1	70	76	PF00069	0.708
TRG_DiLeu_BaEn_1	154	159	PF01217	0.551
TRG_DiLeu_BaLyEn_6	36	41	PF01217	0.510
TRG_ENDOCYTIC_2	171	174	PF00928	0.546
TRG_ENDOCYTIC_2	495	498	PF00928	0.542
TRG_ER_diArg_1	552	554	PF00400	0.625
TRG_ER_diArg_1	67	70	PF00400	0.528
TRG_Pf-PMV_PEXEL_1	114	118	PF00026	0.522
TRG_Pf-PMV_PEXEL_1	420	424	PF00026	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ISS4	Leishmania donovani	69%	100%
A4I702	Leishmania infantum	70%	99%