Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B209_LEIMU

TriTrypDb:

LmxM.30.2100

Length:

383

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B209

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B209

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	166	168	PF00675	0.631
CLV_NRD_NRD_1	180	182	PF00675	0.535
CLV_NRD_NRD_1	203	205	PF00675	0.688
CLV_NRD_NRD_1	206	208	PF00675	0.719
CLV_NRD_NRD_1	240	242	PF00675	0.568
CLV_NRD_NRD_1	314	316	PF00675	0.625
CLV_NRD_NRD_1	330	332	PF00675	0.546
CLV_NRD_NRD_1	9	11	PF00675	0.803
CLV_PCSK_FUR_1	204	208	PF00082	0.622
CLV_PCSK_KEX2_1	166	168	PF00082	0.631
CLV_PCSK_KEX2_1	180	182	PF00082	0.535
CLV_PCSK_KEX2_1	202	204	PF00082	0.684
CLV_PCSK_KEX2_1	206	208	PF00082	0.691
CLV_PCSK_KEX2_1	240	242	PF00082	0.568
CLV_PCSK_KEX2_1	314	316	PF00082	0.625
CLV_PCSK_KEX2_1	330	332	PF00082	0.546
CLV_PCSK_KEX2_1	9	11	PF00082	0.803
CLV_PCSK_PC1ET2_1	202	204	PF00082	0.616
CLV_PCSK_PC7_1	198	204	PF00082	0.572
CLV_PCSK_SKI1_1	210	214	PF00082	0.633
DEG_COP1_1	348	357	PF00400	0.667
DEG_SPOP_SBC_1	135	139	PF00917	0.532
DOC_CKS1_1	76	81	PF01111	0.658
DOC_MAPK_gen_1	240	247	PF00069	0.502
DOC_MAPK_gen_1	314	324	PF00069	0.635
DOC_MAPK_gen_1	6	16	PF00069	0.612
DOC_MAPK_MEF2A_6	315	324	PF00069	0.636
DOC_MAPK_RevD_3	189	204	PF00069	0.616
DOC_PP4_FxxP_1	358	361	PF00568	0.606
DOC_USP7_MATH_1	103	107	PF00917	0.608
DOC_USP7_MATH_1	115	119	PF00917	0.544
DOC_USP7_MATH_1	211	215	PF00917	0.636
DOC_USP7_MATH_1	255	259	PF00917	0.552
DOC_USP7_MATH_1	353	357	PF00917	0.574
DOC_USP7_MATH_1	51	55	PF00917	0.510
DOC_USP7_MATH_1	83	87	PF00917	0.526
DOC_USP7_UBL2_3	307	311	PF12436	0.638
DOC_WW_Pin1_4	17	22	PF00397	0.553
DOC_WW_Pin1_4	184	189	PF00397	0.747
DOC_WW_Pin1_4	228	233	PF00397	0.712
DOC_WW_Pin1_4	347	352	PF00397	0.665
DOC_WW_Pin1_4	35	40	PF00397	0.509
DOC_WW_Pin1_4	71	76	PF00397	0.643
LIG_14-3-3_CanoR_1	167	176	PF00244	0.640
LIG_14-3-3_CanoR_1	240	248	PF00244	0.645
LIG_14-3-3_CanoR_1	314	322	PF00244	0.700
LIG_BIR_II_1	1	5	PF00653	0.683
LIG_BIR_III_2	185	189	PF00653	0.641
LIG_BRCT_BRCA1_1	105	109	PF00533	0.547
LIG_BRCT_BRCA1_1	257	261	PF00533	0.631
LIG_CtBP_PxDLS_1	188	192	PF00389	0.624
LIG_DLG_GKlike_1	90	98	PF00625	0.643
LIG_FHA_1	25	31	PF00498	0.586
LIG_FHA_1	315	321	PF00498	0.631
LIG_FHA_1	40	46	PF00498	0.541
LIG_FHA_1	89	95	PF00498	0.642
LIG_FHA_2	314	320	PF00498	0.630
LIG_Integrin_RGD_1	331	333	PF01839	0.575
LIG_IRF3_LxIS_1	320	325	PF10401	0.644
LIG_LIR_Apic_2	356	361	PF02991	0.608
LIG_LIR_Gen_1	288	295	PF02991	0.709
LIG_LIR_Nem_3	288	294	PF02991	0.708
LIG_Pex14_2	155	159	PF04695	0.498
LIG_SH2_NCK_1	183	187	PF00017	0.508
LIG_SH2_STAT5	293	296	PF00017	0.652
LIG_SH3_1	33	39	PF00018	0.523
LIG_SH3_3	139	145	PF00018	0.606
LIG_SH3_3	229	235	PF00018	0.632
LIG_SH3_3	33	39	PF00018	0.523
LIG_SUMO_SIM_par_1	322	328	PF11976	0.558
LIG_WRC_WIRS_1	156	161	PF05994	0.495
LIG_WRC_WIRS_1	248	253	PF05994	0.574
MOD_CDK_SPK_2	228	233	PF00069	0.635
MOD_CK1_1	137	143	PF00069	0.598
MOD_CK1_1	151	157	PF00069	0.534
MOD_CK1_1	158	164	PF00069	0.561
MOD_CK1_1	165	171	PF00069	0.509
MOD_CK1_1	172	178	PF00069	0.568
MOD_CK1_1	187	193	PF00069	0.687
MOD_CK1_1	214	220	PF00069	0.640
MOD_CK1_1	221	227	PF00069	0.622
MOD_CK1_1	250	256	PF00069	0.574
MOD_CK1_1	287	293	PF00069	0.508
MOD_CK1_1	325	331	PF00069	0.704
MOD_CK1_1	86	92	PF00069	0.617
MOD_CK1_1	93	99	PF00069	0.560
MOD_CK2_1	17	23	PF00069	0.705
MOD_CK2_1	231	237	PF00069	0.677
MOD_CK2_1	313	319	PF00069	0.702
MOD_CK2_1	86	92	PF00069	0.565
MOD_CK2_1	93	99	PF00069	0.587
MOD_DYRK1A_RPxSP_1	35	39	PF00069	0.615
MOD_GlcNHglycan	105	108	PF01048	0.629
MOD_GlcNHglycan	213	216	PF01048	0.641
MOD_GlcNHglycan	253	256	PF01048	0.618
MOD_GlcNHglycan	261	264	PF01048	0.586
MOD_GlcNHglycan	333	336	PF01048	0.674
MOD_GlcNHglycan	340	344	PF01048	0.650
MOD_GlcNHglycan	351	354	PF01048	0.745
MOD_GlcNHglycan	367	370	PF01048	0.530
MOD_GlcNHglycan	42	45	PF01048	0.663
MOD_GlcNHglycan	99	103	PF01048	0.595
MOD_GSK3_1	151	158	PF00069	0.632
MOD_GSK3_1	162	169	PF00069	0.502
MOD_GSK3_1	211	218	PF00069	0.639
MOD_GSK3_1	224	231	PF00069	0.575
MOD_GSK3_1	247	254	PF00069	0.700
MOD_GSK3_1	255	262	PF00069	0.504
MOD_GSK3_1	299	306	PF00069	0.632
MOD_GSK3_1	349	356	PF00069	0.547
MOD_GSK3_1	35	42	PF00069	0.615
MOD_GSK3_1	71	78	PF00069	0.653
MOD_GSK3_1	86	93	PF00069	0.516
MOD_GSK3_1	94	101	PF00069	0.575
MOD_N-GLC_1	148	153	PF02516	0.626
MOD_NEK2_1	155	160	PF00069	0.633
MOD_NEK2_1	24	29	PF00069	0.581
MOD_NEK2_1	247	252	PF00069	0.587
MOD_NEK2_1	40	45	PF00069	0.510
MOD_NEK2_1	98	103	PF00069	0.535
MOD_PIKK_1	126	132	PF00454	0.582
MOD_PK_1	219	225	PF00069	0.670
MOD_PKA_1	166	172	PF00069	0.639
MOD_PKA_1	206	212	PF00069	0.628
MOD_PKA_1	240	246	PF00069	0.503
MOD_PKA_1	314	320	PF00069	0.630
MOD_PKA_2	115	121	PF00069	0.653
MOD_PKA_2	126	132	PF00069	0.582
MOD_PKA_2	165	171	PF00069	0.635
MOD_PKA_2	206	212	PF00069	0.664
MOD_PKA_2	215	221	PF00069	0.586
MOD_PKA_2	240	246	PF00069	0.640
MOD_PKA_2	313	319	PF00069	0.695
MOD_PKB_1	204	212	PF00069	0.626
MOD_Plk_1	287	293	PF00069	0.645
MOD_Plk_1	299	305	PF00069	0.525
MOD_Plk_4	151	157	PF00069	0.630
MOD_Plk_4	192	198	PF00069	0.612
MOD_Plk_4	353	359	PF00069	0.659
MOD_ProDKin_1	17	23	PF00069	0.553
MOD_ProDKin_1	184	190	PF00069	0.744
MOD_ProDKin_1	228	234	PF00069	0.711
MOD_ProDKin_1	347	353	PF00069	0.662
MOD_ProDKin_1	35	41	PF00069	0.509
MOD_ProDKin_1	71	77	PF00069	0.643
TRG_ENDOCYTIC_2	248	251	PF00928	0.618
TRG_ER_diArg_1	206	208	PF00400	0.684
TRG_ER_diArg_1	240	242	PF00400	0.523
TRG_ER_diArg_1	30	33	PF00400	0.666
TRG_ER_diArg_1	313	315	PF00400	0.624
TRG_ER_diArg_1	329	331	PF00400	0.544
TRG_NLS_MonoExtC_3	5	10	PF00514	0.520
TRG_NLS_MonoExtN_4	3	10	PF00514	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4R2	Leishmania donovani	79%	98%
A4I6Y8	Leishmania infantum	79%	98%
Q4Q652	Leishmania major	71%	99%