Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1Z8_LEIMU

TriTrypDb:

LmxM.30.1990

Length:

657

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1Z8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1Z8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.711
CLV_NRD_NRD_1	11	13	PF00675	0.714
CLV_NRD_NRD_1	191	193	PF00675	0.734
CLV_NRD_NRD_1	206	208	PF00675	0.584
CLV_NRD_NRD_1	310	312	PF00675	0.575
CLV_NRD_NRD_1	342	344	PF00675	0.721
CLV_NRD_NRD_1	393	395	PF00675	0.695
CLV_NRD_NRD_1	447	449	PF00675	0.587
CLV_NRD_NRD_1	467	469	PF00675	0.525
CLV_NRD_NRD_1	630	632	PF00675	0.631
CLV_PCSK_FUR_1	445	449	PF00082	0.585
CLV_PCSK_KEX2_1	11	13	PF00082	0.714
CLV_PCSK_KEX2_1	191	193	PF00082	0.734
CLV_PCSK_KEX2_1	206	208	PF00082	0.584
CLV_PCSK_KEX2_1	310	312	PF00082	0.575
CLV_PCSK_KEX2_1	342	344	PF00082	0.721
CLV_PCSK_KEX2_1	393	395	PF00082	0.800
CLV_PCSK_KEX2_1	447	449	PF00082	0.618
CLV_PCSK_KEX2_1	466	468	PF00082	0.532
CLV_PCSK_KEX2_1	629	631	PF00082	0.647
CLV_PCSK_PC7_1	462	468	PF00082	0.599
DEG_COP1_1	182	189	PF00400	0.583
DEG_ODPH_VHL_1	268	281	PF01847	0.546
DEG_SCF_FBW7_1	160	167	PF00400	0.585
DOC_ANK_TNKS_1	92	99	PF00023	0.609
DOC_CKS1_1	477	482	PF01111	0.725
DOC_CKS1_1	537	542	PF01111	0.574
DOC_CYCLIN_RxL_1	204	212	PF00134	0.734
DOC_MAPK_MEF2A_6	405	413	PF00069	0.710
DOC_PP2B_LxvP_1	249	252	PF13499	0.723
DOC_PP2B_LxvP_1	361	364	PF13499	0.709
DOC_PP2B_LxvP_1	534	537	PF13499	0.714
DOC_USP7_MATH_1	133	137	PF00917	0.590
DOC_USP7_MATH_1	253	257	PF00917	0.597
DOC_USP7_MATH_1	319	323	PF00917	0.615
DOC_USP7_MATH_1	417	421	PF00917	0.695
DOC_USP7_MATH_1	523	527	PF00917	0.703
DOC_USP7_MATH_1	598	602	PF00917	0.571
DOC_USP7_MATH_1	60	64	PF00917	0.585
DOC_USP7_MATH_1	617	621	PF00917	0.457
DOC_USP7_MATH_2	499	505	PF00917	0.669
DOC_WW_Pin1_4	106	111	PF00397	0.741
DOC_WW_Pin1_4	122	127	PF00397	0.555
DOC_WW_Pin1_4	131	136	PF00397	0.636
DOC_WW_Pin1_4	160	165	PF00397	0.670
DOC_WW_Pin1_4	209	214	PF00397	0.722
DOC_WW_Pin1_4	240	245	PF00397	0.688
DOC_WW_Pin1_4	335	340	PF00397	0.697
DOC_WW_Pin1_4	476	481	PF00397	0.727
DOC_WW_Pin1_4	536	541	PF00397	0.573
DOC_WW_Pin1_4	56	61	PF00397	0.629
DOC_WW_Pin1_4	583	588	PF00397	0.607
LIG_14-3-3_CanoR_1	108	114	PF00244	0.739
LIG_14-3-3_CanoR_1	137	144	PF00244	0.717
LIG_14-3-3_CanoR_1	323	332	PF00244	0.723
LIG_14-3-3_CanoR_1	351	355	PF00244	0.580
LIG_14-3-3_CanoR_1	448	454	PF00244	0.578
LIG_14-3-3_CanoR_1	505	510	PF00244	0.669
LIG_14-3-3_CanoR_1	54	61	PF00244	0.702
LIG_APCC_ABBAyCdc20_2	546	552	PF00400	0.568
LIG_BIR_II_1	1	5	PF00653	0.707
LIG_BRCT_BRCA1_1	216	220	PF00533	0.618
LIG_BRCT_BRCA1_1	230	234	PF00533	0.631
LIG_BRCT_BRCA1_1	62	66	PF00533	0.581
LIG_CtBP_PxDLS_1	15	19	PF00389	0.598
LIG_EVH1_1	249	253	PF00568	0.581
LIG_FHA_1	327	333	PF00498	0.715
LIG_FHA_1	336	342	PF00498	0.602
LIG_FHA_1	489	495	PF00498	0.667
LIG_FHA_1	555	561	PF00498	0.534
LIG_FHA_2	165	171	PF00498	0.732
LIG_Integrin_isoDGR_2	308	310	PF01839	0.585
LIG_LIR_Apic_2	246	251	PF02991	0.716
LIG_LIR_Gen_1	146	155	PF02991	0.548
LIG_LIR_Gen_1	217	227	PF02991	0.579
LIG_LIR_Gen_1	271	279	PF02991	0.683
LIG_LIR_Gen_1	501	511	PF02991	0.664
LIG_LIR_LC3C_4	35	40	PF02991	0.606
LIG_LIR_Nem_3	188	193	PF02991	0.725
LIG_LIR_Nem_3	217	223	PF02991	0.578
LIG_LIR_Nem_3	271	275	PF02991	0.684
LIG_LIR_Nem_3	384	389	PF02991	0.544
LIG_LIR_Nem_3	430	435	PF02991	0.674
LIG_LIR_Nem_3	501	506	PF02991	0.660
LIG_LIR_Nem_3	638	644	PF02991	0.656
LIG_NRBOX	384	390	PF00104	0.686
LIG_PCNA_yPIPBox_3	382	394	PF02747	0.685
LIG_PTB_Apo_2	607	614	PF02174	0.676
LIG_PTB_Phospho_1	607	613	PF10480	0.679
LIG_SH2_CRK	386	390	PF00017	0.554
LIG_SH2_CRK	477	481	PF00017	0.726
LIG_SH2_CRK	503	507	PF00017	0.661
LIG_SH2_GRB2like	435	438	PF00017	0.687
LIG_SH2_SRC	248	251	PF00017	0.579
LIG_SH2_STAP1	503	507	PF00017	0.661
LIG_SH2_STAP1	642	646	PF00017	0.679
LIG_SH2_STAT5	248	251	PF00017	0.719
LIG_SH2_STAT5	435	438	PF00017	0.687
LIG_SH3_1	259	265	PF00018	0.738
LIG_SH3_3	120	126	PF00018	0.726
LIG_SH3_3	174	180	PF00018	0.732
LIG_SH3_3	247	253	PF00018	0.671
LIG_SH3_3	257	263	PF00018	0.688
LIG_SH3_3	271	277	PF00018	0.516
LIG_SH3_3	504	510	PF00018	0.529
LIG_SH3_3	514	520	PF00018	0.578
LIG_SH3_3	534	540	PF00018	0.502
LIG_SH3_3	584	590	PF00018	0.599
LIG_SH3_3	594	600	PF00018	0.546
LIG_SUMO_SIM_anti_2	368	374	PF11976	0.695
LIG_SUMO_SIM_anti_2	643	649	PF11976	0.547
LIG_SUMO_SIM_par_1	207	212	PF11976	0.730
LIG_WRC_WIRS_1	151	156	PF05994	0.695
LIG_WW_3	261	265	PF00397	0.733
MOD_CDC14_SPxK_1	212	215	PF00782	0.573
MOD_CDK_SPK_2	122	127	PF00069	0.723
MOD_CDK_SPxK_1	131	137	PF00069	0.593
MOD_CDK_SPxK_1	209	215	PF00069	0.581
MOD_CDK_SPxxK_3	335	342	PF00069	0.699
MOD_CK1_1	109	115	PF00069	0.734
MOD_CK1_1	153	159	PF00069	0.701
MOD_CK1_1	17	23	PF00069	0.608
MOD_CK1_1	201	207	PF00069	0.617
MOD_CK1_1	235	241	PF00069	0.667
MOD_CK1_1	288	294	PF00069	0.720
MOD_CK1_1	324	330	PF00069	0.706
MOD_CK1_1	335	341	PF00069	0.595
MOD_CK1_1	42	48	PF00069	0.672
MOD_CK1_1	526	532	PF00069	0.702
MOD_CK1_1	554	560	PF00069	0.616
MOD_CK1_1	581	587	PF00069	0.623
MOD_CK1_1	640	646	PF00069	0.667
MOD_CK1_1	76	82	PF00069	0.577
MOD_CK1_1	83	89	PF00069	0.636
MOD_CK2_1	328	334	PF00069	0.717
MOD_CK2_1	344	350	PF00069	0.553
MOD_CK2_1	600	606	PF00069	0.694
MOD_Cter_Amidation	308	311	PF01082	0.581
MOD_Cter_Amidation	445	448	PF01082	0.585
MOD_DYRK1A_RPxSP_1	56	60	PF00069	0.593
MOD_DYRK1A_RPxSP_1	583	587	PF00069	0.607
MOD_GlcNHglycan	119	122	PF01048	0.743
MOD_GlcNHglycan	131	134	PF01048	0.612
MOD_GlcNHglycan	155	158	PF01048	0.705
MOD_GlcNHglycan	200	203	PF01048	0.598
MOD_GlcNHglycan	21	24	PF01048	0.611
MOD_GlcNHglycan	224	227	PF01048	0.677
MOD_GlcNHglycan	230	233	PF01048	0.658
MOD_GlcNHglycan	237	240	PF01048	0.568
MOD_GlcNHglycan	312	315	PF01048	0.716
MOD_GlcNHglycan	323	326	PF01048	0.616
MOD_GlcNHglycan	334	337	PF01048	0.667
MOD_GlcNHglycan	346	349	PF01048	0.593
MOD_GlcNHglycan	440	443	PF01048	0.702
MOD_GlcNHglycan	457	460	PF01048	0.551
MOD_GlcNHglycan	525	528	PF01048	0.699
MOD_GlcNHglycan	554	557	PF01048	0.677
MOD_GlcNHglycan	56	59	PF01048	0.602
MOD_GlcNHglycan	569	572	PF01048	0.544
MOD_GlcNHglycan	75	78	PF01048	0.604
MOD_GlcNHglycan	82	85	PF01048	0.624
MOD_GlcNHglycan	88	91	PF01048	0.581
MOD_GSK3_1	129	136	PF00069	0.662
MOD_GSK3_1	139	146	PF00069	0.668
MOD_GSK3_1	14	21	PF00069	0.602
MOD_GSK3_1	156	163	PF00069	0.521
MOD_GSK3_1	171	178	PF00069	0.682
MOD_GSK3_1	181	188	PF00069	0.621
MOD_GSK3_1	228	235	PF00069	0.676
MOD_GSK3_1	240	247	PF00069	0.568
MOD_GSK3_1	285	292	PF00069	0.709
MOD_GSK3_1	319	326	PF00069	0.735
MOD_GSK3_1	328	335	PF00069	0.622
MOD_GSK3_1	346	353	PF00069	0.532
MOD_GSK3_1	423	430	PF00069	0.601
MOD_GSK3_1	433	440	PF00069	0.650
MOD_GSK3_1	448	455	PF00069	0.560
MOD_GSK3_1	476	483	PF00069	0.723
MOD_GSK3_1	50	57	PF00069	0.688
MOD_GSK3_1	501	508	PF00069	0.662
MOD_GSK3_1	526	533	PF00069	0.703
MOD_GSK3_1	579	586	PF00069	0.738
MOD_GSK3_1	588	595	PF00069	0.630
MOD_GSK3_1	645	652	PF00069	0.695
MOD_GSK3_1	65	72	PF00069	0.524
MOD_GSK3_1	73	80	PF00069	0.626
MOD_LATS_1	115	121	PF00433	0.740
MOD_LATS_1	52	58	PF00433	0.710
MOD_N-GLC_1	193	198	PF02516	0.728
MOD_N-GLC_1	4	9	PF02516	0.702
MOD_N-GLC_1	45	50	PF02516	0.593
MOD_N-GLC_1	494	499	PF02516	0.685
MOD_N-GLC_1	579	584	PF02516	0.615
MOD_NEK2_1	139	144	PF00069	0.712
MOD_NEK2_1	150	155	PF00069	0.576
MOD_NEK2_1	18	23	PF00069	0.610
MOD_NEK2_1	481	486	PF00069	0.718
MOD_NEK2_1	530	535	PF00069	0.712
MOD_NEK2_1	560	565	PF00069	0.684
MOD_NEK2_2	65	70	PF00069	0.574
MOD_PIKK_1	137	143	PF00454	0.706
MOD_PIKK_1	181	187	PF00454	0.585
MOD_PIKK_1	232	238	PF00454	0.531
MOD_PIKK_1	253	259	PF00454	0.603
MOD_PIKK_1	350	356	PF00454	0.583
MOD_PIKK_1	4	10	PF00454	0.703
MOD_PIKK_1	560	566	PF00454	0.544
MOD_PIKK_1	649	655	PF00454	0.711
MOD_PK_1	264	270	PF00069	0.714
MOD_PK_1	295	301	PF00069	0.576
MOD_PKA_1	310	316	PF00069	0.577
MOD_PKA_2	214	220	PF00069	0.576
MOD_PKA_2	310	316	PF00069	0.717
MOD_PKA_2	350	356	PF00069	0.583
MOD_PKA_2	411	417	PF00069	0.566
MOD_PKA_2	567	573	PF00069	0.602
MOD_PKA_2	617	623	PF00069	0.515
MOD_Plk_1	115	121	PF00069	0.740
MOD_Plk_1	295	301	PF00069	0.716
MOD_Plk_1	637	643	PF00069	0.648
MOD_Plk_2-3	488	494	PF00069	0.719
MOD_Plk_4	150	156	PF00069	0.693
MOD_Plk_4	185	191	PF00069	0.587
MOD_Plk_4	244	250	PF00069	0.708
MOD_Plk_4	526	532	PF00069	0.702
MOD_Plk_4	637	643	PF00069	0.648
MOD_ProDKin_1	106	112	PF00069	0.741
MOD_ProDKin_1	122	128	PF00069	0.554
MOD_ProDKin_1	131	137	PF00069	0.638
MOD_ProDKin_1	160	166	PF00069	0.674
MOD_ProDKin_1	209	215	PF00069	0.721
MOD_ProDKin_1	240	246	PF00069	0.690
MOD_ProDKin_1	335	341	PF00069	0.697
MOD_ProDKin_1	476	482	PF00069	0.726
MOD_ProDKin_1	536	542	PF00069	0.574
MOD_ProDKin_1	56	62	PF00069	0.631
MOD_ProDKin_1	583	589	PF00069	0.607
MOD_SUMO_rev_2	616	622	PF00179	0.658
TRG_DiLeu_BaEn_1	368	373	PF01217	0.694
TRG_DiLeu_BaEn_1	384	389	PF01217	0.516
TRG_DiLeu_LyEn_5	384	389	PF01217	0.684
TRG_ENDOCYTIC_2	147	150	PF00928	0.545
TRG_ENDOCYTIC_2	272	275	PF00928	0.681
TRG_ENDOCYTIC_2	386	389	PF00928	0.553
TRG_ENDOCYTIC_2	503	506	PF00928	0.661
TRG_ENDOCYTIC_2	641	644	PF00928	0.665
TRG_ER_diArg_1	190	192	PF00400	0.732
TRG_ER_diArg_1	206	208	PF00400	0.573
TRG_ER_diArg_1	341	343	PF00400	0.582
TRG_ER_diArg_1	360	363	PF00400	0.642
TRG_ER_diArg_1	392	394	PF00400	0.700
TRG_ER_diArg_1	445	448	PF00400	0.585
TRG_ER_diArg_1	466	468	PF00400	0.599
TRG_ER_diArg_1	629	631	PF00400	0.647
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q4Q663	Leishmania major	73%	100%