LeishMANIAdb
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Transcriptional regulator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transcriptional regulator
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B1Z7_LEIMU
TriTrypDb:
LmxM.30.1980
Length:
47

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1Z7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1Z7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 29 31 PF00675 0.503
CLV_NRD_NRD_1 39 41 PF00675 0.456
CLV_NRD_NRD_1 43 45 PF00675 0.581
CLV_PCSK_KEX2_1 29 31 PF00082 0.703
CLV_PCSK_KEX2_1 39 41 PF00082 0.541
CLV_PCSK_KEX2_1 43 45 PF00082 0.610
CLV_PCSK_KEX2_1 5 7 PF00082 0.689
CLV_PCSK_PC1ET2_1 39 41 PF00082 0.591
CLV_PCSK_PC1ET2_1 5 7 PF00082 0.689
DEG_Nend_UBRbox_2 1 3 PF02207 0.644
DOC_MAPK_RevD_3 14 30 PF00069 0.487
DOC_USP7_MATH_1 8 12 PF00917 0.481
DOC_WW_Pin1_4 4 9 PF00397 0.489
LIG_BRCT_BRCA1_1 10 14 PF00533 0.477
LIG_FHA_2 13 19 PF00498 0.655
MOD_CK1_1 31 37 PF00069 0.484
MOD_CK2_1 12 18 PF00069 0.656
MOD_GlcNHglycan 33 36 PF01048 0.482
MOD_GSK3_1 4 11 PF00069 0.486
MOD_PKA_2 28 34 PF00069 0.501
MOD_ProDKin_1 4 10 PF00069 0.488
TRG_ER_diArg_1 29 32 PF00400 0.504
TRG_NLS_Bipartite_1 29 44 PF00514 0.492
TRG_NLS_MonoExtC_3 38 43 PF00514 0.492
TRG_NLS_MonoExtN_4 39 44 PF00514 0.494

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IEY9 Leishmania donovani 67% 67%
A4I6X3 Leishmania infantum 72% 67%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS