Putative transcription like protein nupm1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription like protein nupm1, putative

Species:

Leishmania mexicana

UniProt:

E9B1Z3_LEIMU

TriTrypDb:

LmxM.30.1940

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

E9B1Z3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1Z3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.667
CLV_C14_Caspase3-7	196	200	PF00656	0.654
CLV_C14_Caspase3-7	58	62	PF00656	0.639
CLV_NRD_NRD_1	104	106	PF00675	0.469
CLV_NRD_NRD_1	111	113	PF00675	0.465
CLV_NRD_NRD_1	234	236	PF00675	0.484
CLV_NRD_NRD_1	410	412	PF00675	0.579
CLV_NRD_NRD_1	48	50	PF00675	0.542
CLV_NRD_NRD_1	74	76	PF00675	0.412
CLV_PCSK_FUR_1	231	235	PF00082	0.490
CLV_PCSK_FUR_1	411	415	PF00082	0.545
CLV_PCSK_KEX2_1	103	105	PF00082	0.470
CLV_PCSK_KEX2_1	111	113	PF00082	0.461
CLV_PCSK_KEX2_1	233	235	PF00082	0.490
CLV_PCSK_KEX2_1	410	412	PF00082	0.584
CLV_PCSK_KEX2_1	413	415	PF00082	0.575
CLV_PCSK_KEX2_1	48	50	PF00082	0.538
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.470
CLV_PCSK_PC1ET2_1	413	415	PF00082	0.551
CLV_PCSK_PC7_1	229	235	PF00082	0.472
CLV_PCSK_PC7_1	406	412	PF00082	0.446
CLV_Separin_Metazoa	92	96	PF03568	0.670
DEG_APCC_DBOX_1	148	156	PF00400	0.626
DEG_Kelch_Keap1_1	62	67	PF01344	0.834
DEG_SCF_FBW7_2	85	92	PF00400	0.646
DEG_SPOP_SBC_1	159	163	PF00917	0.755
DOC_CKS1_1	429	434	PF01111	0.695
DOC_CYCLIN_yCln2_LP_2	471	477	PF00134	0.677
DOC_PP2B_LxvP_1	173	176	PF13499	0.724
DOC_PP4_FxxP_1	429	432	PF00568	0.743
DOC_USP7_MATH_1	141	145	PF00917	0.833
DOC_USP7_MATH_1	289	293	PF00917	0.862
DOC_USP7_MATH_1	300	304	PF00917	0.728
DOC_USP7_MATH_1	355	359	PF00917	0.852
DOC_USP7_MATH_1	443	447	PF00917	0.803
DOC_USP7_MATH_1	454	458	PF00917	0.755
DOC_USP7_MATH_1	70	74	PF00917	0.745
DOC_USP7_MATH_1	79	83	PF00917	0.720
DOC_USP7_UBL2_3	413	417	PF12436	0.769
DOC_USP7_UBL2_3	97	101	PF12436	0.635
DOC_WW_Pin1_4	344	349	PF00397	0.726
DOC_WW_Pin1_4	376	381	PF00397	0.734
DOC_WW_Pin1_4	428	433	PF00397	0.707
DOC_WW_Pin1_4	53	58	PF00397	0.706
DOC_WW_Pin1_4	85	90	PF00397	0.651
LIG_14-3-3_CanoR_1	149	159	PF00244	0.754
LIG_14-3-3_CanoR_1	160	166	PF00244	0.768
LIG_14-3-3_CanoR_1	169	173	PF00244	0.630
LIG_14-3-3_CanoR_1	211	217	PF00244	0.713
LIG_14-3-3_CanoR_1	302	307	PF00244	0.780
LIG_14-3-3_CanoR_1	411	417	PF00244	0.751
LIG_Actin_WH2_2	23	39	PF00022	0.220
LIG_BRCT_BRCA1_1	291	295	PF00533	0.672
LIG_BRCT_BRCA1_1	323	327	PF00533	0.748
LIG_BRCT_BRCA1_1	425	429	PF00533	0.750
LIG_Clathr_ClatBox_1	328	332	PF01394	0.742
LIG_FHA_1	160	166	PF00498	0.751
LIG_FHA_1	179	185	PF00498	0.706
LIG_FHA_1	6	12	PF00498	0.227
LIG_FHA_2	132	138	PF00498	0.693
LIG_FHA_2	276	282	PF00498	0.716
LIG_FHA_2	413	419	PF00498	0.696
LIG_GBD_Chelix_1	216	224	PF00786	0.418
LIG_GBD_Chelix_1	23	31	PF00786	0.243
LIG_Integrin_isoDGR_2	40	42	PF01839	0.376
LIG_LIR_Apic_2	170	175	PF02991	0.822
LIG_LIR_Apic_2	426	432	PF02991	0.738
LIG_LIR_Gen_1	292	300	PF02991	0.638
LIG_LIR_Nem_3	292	298	PF02991	0.642
LIG_LIR_Nem_3	324	328	PF02991	0.812
LIG_LIR_Nem_3	415	419	PF02991	0.698
LIG_LYPXL_yS_3	325	328	PF13949	0.824
LIG_MLH1_MIPbox_1	425	429	PF16413	0.750
LIG_MYND_1	85	89	PF01753	0.689
LIG_PCNA_yPIPBox_3	417	429	PF02747	0.744
LIG_SH2_GRB2like	370	373	PF00017	0.712
LIG_SH2_STAP1	249	253	PF00017	0.654
LIG_SH2_STAT5	172	175	PF00017	0.749
LIG_SH2_STAT5	32	35	PF00017	0.413
LIG_SH3_3	455	461	PF00018	0.765
LIG_Sin3_3	7	14	PF02671	0.285
LIG_TRAF2_1	107	110	PF00917	0.672
LIG_TRAF2_1	313	316	PF00917	0.636
LIG_TRAF2_1	89	92	PF00917	0.679
LIG_WW_3	83	87	PF00397	0.634
MOD_CDK_SPxK_1	53	59	PF00069	0.516
MOD_CK1_1	144	150	PF00069	0.711
MOD_CK1_1	154	160	PF00069	0.711
MOD_CK1_1	192	198	PF00069	0.739
MOD_CK1_1	201	207	PF00069	0.727
MOD_CK1_1	210	216	PF00069	0.673
MOD_CK1_1	256	262	PF00069	0.679
MOD_CK1_1	266	272	PF00069	0.724
MOD_CK1_1	305	311	PF00069	0.728
MOD_CK1_1	368	374	PF00069	0.748
MOD_CK1_1	430	436	PF00069	0.620
MOD_CK1_1	439	445	PF00069	0.722
MOD_CK2_1	131	137	PF00069	0.812
MOD_CK2_1	251	257	PF00069	0.590
MOD_CK2_1	61	67	PF00069	0.814
MOD_GlcNHglycan	176	179	PF01048	0.689
MOD_GlcNHglycan	206	209	PF01048	0.679
MOD_GlcNHglycan	264	268	PF01048	0.775
MOD_GlcNHglycan	3	6	PF01048	0.543
MOD_GlcNHglycan	302	305	PF01048	0.756
MOD_GlcNHglycan	308	311	PF01048	0.706
MOD_GlcNHglycan	357	360	PF01048	0.681
MOD_GlcNHglycan	395	398	PF01048	0.692
MOD_GlcNHglycan	425	428	PF01048	0.634
MOD_GlcNHglycan	458	461	PF01048	0.743
MOD_GSK3_1	1	8	PF00069	0.492
MOD_GSK3_1	141	148	PF00069	0.665
MOD_GSK3_1	150	157	PF00069	0.635
MOD_GSK3_1	174	181	PF00069	0.622
MOD_GSK3_1	189	196	PF00069	0.667
MOD_GSK3_1	200	207	PF00069	0.756
MOD_GSK3_1	252	259	PF00069	0.641
MOD_GSK3_1	275	282	PF00069	0.760
MOD_GSK3_1	285	292	PF00069	0.725
MOD_GSK3_1	302	309	PF00069	0.741
MOD_GSK3_1	351	358	PF00069	0.714
MOD_GSK3_1	361	368	PF00069	0.741
MOD_GSK3_1	372	379	PF00069	0.685
MOD_GSK3_1	393	400	PF00069	0.680
MOD_GSK3_1	423	430	PF00069	0.537
MOD_GSK3_1	439	446	PF00069	0.710
MOD_N-GLC_1	189	194	PF02516	0.526
MOD_N-GLC_1	300	305	PF02516	0.540
MOD_N-GLC_1	371	376	PF02516	0.578
MOD_NEK2_1	1	6	PF00069	0.579
MOD_NEK2_1	258	263	PF00069	0.771
MOD_NEK2_1	36	41	PF00069	0.478
MOD_NEK2_1	465	470	PF00069	0.648
MOD_NEK2_1	60	65	PF00069	0.814
MOD_NEK2_2	178	183	PF00069	0.631
MOD_PIKK_1	110	116	PF00454	0.592
MOD_PIKK_1	210	216	PF00454	0.679
MOD_PIKK_1	266	272	PF00454	0.827
MOD_PIKK_1	70	76	PF00454	0.487
MOD_PK_1	302	308	PF00069	0.740
MOD_PKA_2	110	116	PF00069	0.592
MOD_PKA_2	148	154	PF00069	0.705
MOD_PKA_2	159	165	PF00069	0.722
MOD_PKA_2	168	174	PF00069	0.526
MOD_PKA_2	192	198	PF00069	0.785
MOD_PKA_2	201	207	PF00069	0.670
MOD_PKA_2	210	216	PF00069	0.502
MOD_PKA_2	359	365	PF00069	0.560
MOD_PKB_1	283	291	PF00069	0.796
MOD_Plk_1	178	184	PF00069	0.632
MOD_Plk_2-3	337	343	PF00069	0.585
MOD_Plk_4	168	174	PF00069	0.761
MOD_ProDKin_1	344	350	PF00069	0.665
MOD_ProDKin_1	376	382	PF00069	0.677
MOD_ProDKin_1	428	434	PF00069	0.633
MOD_ProDKin_1	53	59	PF00069	0.636
MOD_ProDKin_1	85	91	PF00069	0.553
TRG_DiLeu_BaEn_4	236	242	PF01217	0.584
TRG_ENDOCYTIC_2	249	252	PF00928	0.563
TRG_ENDOCYTIC_2	325	328	PF00928	0.696
TRG_ER_diArg_1	224	227	PF00400	0.613
TRG_ER_diArg_1	229	232	PF00400	0.612
TRG_ER_diArg_1	233	235	PF00400	0.613
TRG_ER_diArg_1	409	411	PF00400	0.735
TRG_ER_diArg_1	48	50	PF00400	0.670
TRG_NLS_MonoExtN_4	101	107	PF00514	0.579
TRG_Pf-PMV_PEXEL_1	312	316	PF00026	0.710
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.595

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGX0	Leptomonas seymouri	44%	98%
A0A3Q8IGF6	Leishmania donovani	82%	100%
A4HJH6	Leishmania braziliensis	60%	97%
A4HJX3	Leishmania braziliensis	60%	97%
A4I6W9	Leishmania infantum	82%	100%
Q4Q668	Leishmania major	79%	100%