LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B1X1_LEIMU
TriTrypDb:
LmxM.30.1710
Length:
706

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1X1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1X1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 290 294 PF00656 0.699
CLV_C14_Caspase3-7 395 399 PF00656 0.515
CLV_C14_Caspase3-7 605 609 PF00656 0.687
CLV_NRD_NRD_1 121 123 PF00675 0.720
CLV_NRD_NRD_1 182 184 PF00675 0.504
CLV_NRD_NRD_1 19 21 PF00675 0.644
CLV_NRD_NRD_1 388 390 PF00675 0.511
CLV_NRD_NRD_1 486 488 PF00675 0.665
CLV_NRD_NRD_1 555 557 PF00675 0.623
CLV_NRD_NRD_1 628 630 PF00675 0.531
CLV_PCSK_FUR_1 17 21 PF00082 0.595
CLV_PCSK_FUR_1 180 184 PF00082 0.499
CLV_PCSK_KEX2_1 117 119 PF00082 0.698
CLV_PCSK_KEX2_1 121 123 PF00082 0.695
CLV_PCSK_KEX2_1 17 19 PF00082 0.635
CLV_PCSK_KEX2_1 182 184 PF00082 0.504
CLV_PCSK_KEX2_1 390 392 PF00082 0.564
CLV_PCSK_KEX2_1 486 488 PF00082 0.665
CLV_PCSK_KEX2_1 554 556 PF00082 0.620
CLV_PCSK_KEX2_1 603 605 PF00082 0.659
CLV_PCSK_PC1ET2_1 117 119 PF00082 0.634
CLV_PCSK_PC1ET2_1 390 392 PF00082 0.538
CLV_PCSK_PC1ET2_1 603 605 PF00082 0.659
CLV_PCSK_PC7_1 386 392 PF00082 0.534
CLV_PCSK_SKI1_1 446 450 PF00082 0.526
CLV_PCSK_SKI1_1 480 484 PF00082 0.698
CLV_PCSK_SKI1_1 548 552 PF00082 0.735
DEG_Nend_UBRbox_1 1 4 PF02207 0.537
DEG_SPOP_SBC_1 64 68 PF00917 0.786
DOC_ANK_TNKS_1 323 330 PF00023 0.655
DOC_CDC14_PxL_1 470 478 PF14671 0.626
DOC_CKS1_1 22 27 PF01111 0.611
DOC_CKS1_1 316 321 PF01111 0.778
DOC_CKS1_1 41 46 PF01111 0.627
DOC_MAPK_MEF2A_6 462 470 PF00069 0.646
DOC_PP2B_LxvP_1 187 190 PF13499 0.524
DOC_PP4_FxxP_1 499 502 PF00568 0.665
DOC_USP7_MATH_1 105 109 PF00917 0.739
DOC_USP7_MATH_1 160 164 PF00917 0.688
DOC_USP7_MATH_1 197 201 PF00917 0.735
DOC_USP7_MATH_1 26 30 PF00917 0.556
DOC_USP7_MATH_1 297 301 PF00917 0.639
DOC_USP7_MATH_1 311 315 PF00917 0.745
DOC_USP7_MATH_1 336 340 PF00917 0.511
DOC_USP7_MATH_1 521 525 PF00917 0.645
DOC_USP7_MATH_1 531 535 PF00917 0.557
DOC_USP7_MATH_1 73 77 PF00917 0.620
DOC_USP7_UBL2_3 123 127 PF12436 0.624
DOC_USP7_UBL2_3 626 630 PF12436 0.531
DOC_WW_Pin1_4 155 160 PF00397 0.665
DOC_WW_Pin1_4 165 170 PF00397 0.612
DOC_WW_Pin1_4 171 176 PF00397 0.665
DOC_WW_Pin1_4 21 26 PF00397 0.613
DOC_WW_Pin1_4 27 32 PF00397 0.639
DOC_WW_Pin1_4 307 312 PF00397 0.796
DOC_WW_Pin1_4 315 320 PF00397 0.694
DOC_WW_Pin1_4 37 42 PF00397 0.727
DOC_WW_Pin1_4 372 377 PF00397 0.653
DOC_WW_Pin1_4 438 443 PF00397 0.737
DOC_WW_Pin1_4 480 485 PF00397 0.678
DOC_WW_Pin1_4 614 619 PF00397 0.725
DOC_WW_Pin1_4 638 643 PF00397 0.704
DOC_WW_Pin1_4 701 706 PF00397 0.485
DOC_WW_Pin1_4 81 86 PF00397 0.789
LIG_14-3-3_CanoR_1 19 25 PF00244 0.701
LIG_14-3-3_CanoR_1 2 10 PF00244 0.546
LIG_14-3-3_CanoR_1 380 385 PF00244 0.639
LIG_14-3-3_CanoR_1 389 394 PF00244 0.544
LIG_14-3-3_CanoR_1 451 457 PF00244 0.732
LIG_14-3-3_CanoR_1 510 515 PF00244 0.734
LIG_14-3-3_CanoR_1 554 560 PF00244 0.597
LIG_14-3-3_CanoR_1 610 615 PF00244 0.677
LIG_14-3-3_CanoR_1 88 94 PF00244 0.665
LIG_14-3-3_CanoR_1 96 101 PF00244 0.636
LIG_Actin_WH2_2 642 660 PF00022 0.488
LIG_APCC_ABBA_1 237 242 PF00400 0.634
LIG_BRCT_BRCA1_1 538 542 PF00533 0.537
LIG_deltaCOP1_diTrp_1 218 226 PF00928 0.586
LIG_deltaCOP1_diTrp_1 420 426 PF00928 0.530
LIG_DLG_GKlike_1 510 517 PF00625 0.640
LIG_eIF4E_1 656 662 PF01652 0.613
LIG_FHA_1 303 309 PF00498 0.646
LIG_FHA_1 34 40 PF00498 0.612
LIG_FHA_1 41 47 PF00498 0.547
LIG_FHA_1 426 432 PF00498 0.571
LIG_FHA_1 59 65 PF00498 0.625
LIG_FHA_1 609 615 PF00498 0.642
LIG_FHA_1 9 15 PF00498 0.539
LIG_FHA_2 228 234 PF00498 0.568
LIG_FHA_2 373 379 PF00498 0.521
LIG_GBD_Chelix_1 649 657 PF00786 0.453
LIG_LIR_Apic_2 469 474 PF02991 0.554
LIG_LIR_Gen_1 150 160 PF02991 0.498
LIG_LIR_Gen_1 420 429 PF02991 0.681
LIG_LIR_Gen_1 654 663 PF02991 0.494
LIG_LIR_Gen_1 682 693 PF02991 0.633
LIG_LIR_Nem_3 134 138 PF02991 0.608
LIG_LIR_Nem_3 150 155 PF02991 0.487
LIG_LIR_Nem_3 238 243 PF02991 0.683
LIG_LIR_Nem_3 279 285 PF02991 0.543
LIG_LIR_Nem_3 339 344 PF02991 0.598
LIG_LIR_Nem_3 409 415 PF02991 0.550
LIG_LIR_Nem_3 420 425 PF02991 0.629
LIG_LIR_Nem_3 469 473 PF02991 0.570
LIG_LIR_Nem_3 539 545 PF02991 0.563
LIG_LIR_Nem_3 597 602 PF02991 0.485
LIG_LIR_Nem_3 654 659 PF02991 0.602
LIG_LIR_Nem_3 682 688 PF02991 0.638
LIG_LYPXL_yS_3 282 285 PF13949 0.542
LIG_MYND_1 190 194 PF01753 0.508
LIG_Pex14_1 422 426 PF04695 0.530
LIG_Pex14_1 669 673 PF04695 0.471
LIG_SH2_CRK 135 139 PF00017 0.603
LIG_SH2_CRK 152 156 PF00017 0.484
LIG_SH2_CRK 471 475 PF00017 0.448
LIG_SH2_NCK_1 471 475 PF00017 0.448
LIG_SH2_STAP1 694 698 PF00017 0.562
LIG_SH2_STAT3 667 670 PF00017 0.488
LIG_SH2_STAT5 152 155 PF00017 0.506
LIG_SH2_STAT5 227 230 PF00017 0.692
LIG_SH2_STAT5 412 415 PF00017 0.538
LIG_SH2_STAT5 576 579 PF00017 0.476
LIG_SH2_STAT5 601 604 PF00017 0.514
LIG_SH2_STAT5 648 651 PF00017 0.473
LIG_SH2_STAT5 656 659 PF00017 0.481
LIG_SH3_1 47 53 PF00018 0.541
LIG_SH3_2 316 321 PF14604 0.708
LIG_SH3_3 163 169 PF00018 0.564
LIG_SH3_3 187 193 PF00018 0.563
LIG_SH3_3 19 25 PF00018 0.688
LIG_SH3_3 313 319 PF00018 0.768
LIG_SH3_3 38 44 PF00018 0.703
LIG_SH3_3 439 445 PF00018 0.727
LIG_SH3_3 47 53 PF00018 0.577
LIG_SH3_3 492 498 PF00018 0.768
LIG_SH3_3 609 615 PF00018 0.702
LIG_SUMO_SIM_par_1 608 617 PF11976 0.577
LIG_SxIP_EBH_1 158 170 PF03271 0.514
LIG_TYR_ITIM 413 418 PF00017 0.469
MOD_CDK_SPK_2 165 170 PF00069 0.636
MOD_CDK_SPK_2 441 446 PF00069 0.674
MOD_CDK_SPxK_1 315 321 PF00069 0.706
MOD_CDK_SPxK_1 480 486 PF00069 0.677
MOD_CDK_SPxxK_3 40 47 PF00069 0.537
MOD_CDK_SPxxK_3 480 487 PF00069 0.673
MOD_CDK_SPxxK_3 81 88 PF00069 0.717
MOD_CK1_1 107 113 PF00069 0.588
MOD_CK1_1 147 153 PF00069 0.625
MOD_CK1_1 196 202 PF00069 0.743
MOD_CK1_1 251 257 PF00069 0.539
MOD_CK1_1 27 33 PF00069 0.623
MOD_CK1_1 306 312 PF00069 0.689
MOD_CK1_1 35 41 PF00069 0.686
MOD_CK1_1 362 368 PF00069 0.656
MOD_CK1_1 370 376 PF00069 0.677
MOD_CK1_1 392 398 PF00069 0.500
MOD_CK1_1 403 409 PF00069 0.557
MOD_CK1_1 440 446 PF00069 0.762
MOD_CK1_1 5 11 PF00069 0.683
MOD_CK1_1 520 526 PF00069 0.615
MOD_CK1_1 536 542 PF00069 0.576
MOD_CK1_1 549 555 PF00069 0.741
MOD_CK1_1 613 619 PF00069 0.745
MOD_CK1_1 632 638 PF00069 0.700
MOD_CK1_1 83 89 PF00069 0.732
MOD_CK1_1 95 101 PF00069 0.666
MOD_CK2_1 227 233 PF00069 0.573
MOD_CK2_1 372 378 PF00069 0.603
MOD_CK2_1 441 447 PF00069 0.615
MOD_CK2_1 516 522 PF00069 0.732
MOD_CK2_1 563 569 PF00069 0.681
MOD_CK2_1 648 654 PF00069 0.595
MOD_CK2_1 689 695 PF00069 0.677
MOD_CK2_1 9 15 PF00069 0.698
MOD_Cter_Amidation 15 18 PF01082 0.639
MOD_Cter_Amidation 627 630 PF01082 0.530
MOD_GlcNHglycan 107 110 PF01048 0.714
MOD_GlcNHglycan 162 165 PF01048 0.657
MOD_GlcNHglycan 195 198 PF01048 0.581
MOD_GlcNHglycan 293 297 PF01048 0.656
MOD_GlcNHglycan 361 364 PF01048 0.523
MOD_GlcNHglycan 456 459 PF01048 0.706
MOD_GlcNHglycan 519 522 PF01048 0.656
MOD_GlcNHglycan 619 622 PF01048 0.677
MOD_GlcNHglycan 637 640 PF01048 0.534
MOD_GlcNHglycan 642 645 PF01048 0.569
MOD_GlcNHglycan 674 677 PF01048 0.643
MOD_GlcNHglycan 691 694 PF01048 0.451
MOD_GlcNHglycan 73 76 PF01048 0.648
MOD_GlcNHglycan 85 88 PF01048 0.600
MOD_GSK3_1 107 114 PF00069 0.807
MOD_GSK3_1 144 151 PF00069 0.681
MOD_GSK3_1 155 162 PF00069 0.608
MOD_GSK3_1 188 195 PF00069 0.769
MOD_GSK3_1 2 9 PF00069 0.688
MOD_GSK3_1 20 27 PF00069 0.541
MOD_GSK3_1 244 251 PF00069 0.726
MOD_GSK3_1 264 271 PF00069 0.677
MOD_GSK3_1 302 309 PF00069 0.808
MOD_GSK3_1 311 318 PF00069 0.595
MOD_GSK3_1 33 40 PF00069 0.584
MOD_GSK3_1 421 428 PF00069 0.540
MOD_GSK3_1 433 440 PF00069 0.626
MOD_GSK3_1 454 461 PF00069 0.622
MOD_GSK3_1 462 469 PF00069 0.602
MOD_GSK3_1 516 523 PF00069 0.621
MOD_GSK3_1 59 66 PF00069 0.684
MOD_GSK3_1 606 613 PF00069 0.713
MOD_GSK3_1 629 636 PF00069 0.754
MOD_GSK3_1 697 704 PF00069 0.501
MOD_GSK3_1 92 99 PF00069 0.738
MOD_N-GLC_1 105 110 PF02516 0.780
MOD_N-GLC_1 285 290 PF02516 0.528
MOD_N-GLC_1 303 308 PF02516 0.780
MOD_N-GLC_1 689 694 PF02516 0.506
MOD_NEK2_1 112 117 PF00069 0.696
MOD_NEK2_1 148 153 PF00069 0.670
MOD_NEK2_1 220 225 PF00069 0.583
MOD_NEK2_1 400 405 PF00069 0.518
MOD_NEK2_1 425 430 PF00069 0.555
MOD_NEK2_1 433 438 PF00069 0.619
MOD_NEK2_1 491 496 PF00069 0.598
MOD_NEK2_1 65 70 PF00069 0.731
MOD_NEK2_1 671 676 PF00069 0.513
MOD_NEK2_1 698 703 PF00069 0.654
MOD_NEK2_2 297 302 PF00069 0.640
MOD_NEK2_2 421 426 PF00069 0.530
MOD_NEK2_2 538 543 PF00069 0.517
MOD_PIKK_1 107 113 PF00454 0.655
MOD_PIKK_1 362 368 PF00454 0.726
MOD_PIKK_1 406 412 PF00454 0.637
MOD_PIKK_1 446 452 PF00454 0.528
MOD_PK_1 389 395 PF00069 0.515
MOD_PK_1 462 468 PF00069 0.650
MOD_PKA_1 117 123 PF00069 0.637
MOD_PKA_1 389 395 PF00069 0.481
MOD_PKA_1 554 560 PF00069 0.619
MOD_PKA_1 629 635 PF00069 0.591
MOD_PKA_2 117 123 PF00069 0.682
MOD_PKA_2 370 376 PF00069 0.503
MOD_PKA_2 491 497 PF00069 0.711
MOD_PKA_2 554 560 PF00069 0.615
MOD_PKA_2 89 95 PF00069 0.654
MOD_PKB_1 18 26 PF00069 0.545
MOD_Plk_1 303 309 PF00069 0.747
MOD_Plk_1 354 360 PF00069 0.453
MOD_Plk_1 689 695 PF00069 0.508
MOD_Plk_4 144 150 PF00069 0.495
MOD_Plk_4 421 427 PF00069 0.536
MOD_Plk_4 466 472 PF00069 0.579
MOD_Plk_4 491 497 PF00069 0.727
MOD_Plk_4 538 544 PF00069 0.577
MOD_Plk_4 555 561 PF00069 0.619
MOD_Plk_4 594 600 PF00069 0.623
MOD_Plk_4 679 685 PF00069 0.651
MOD_Plk_4 96 102 PF00069 0.717
MOD_ProDKin_1 155 161 PF00069 0.668
MOD_ProDKin_1 165 171 PF00069 0.611
MOD_ProDKin_1 21 27 PF00069 0.612
MOD_ProDKin_1 307 313 PF00069 0.796
MOD_ProDKin_1 315 321 PF00069 0.694
MOD_ProDKin_1 37 43 PF00069 0.738
MOD_ProDKin_1 372 378 PF00069 0.647
MOD_ProDKin_1 438 444 PF00069 0.737
MOD_ProDKin_1 480 486 PF00069 0.677
MOD_ProDKin_1 614 620 PF00069 0.725
MOD_ProDKin_1 638 644 PF00069 0.693
MOD_ProDKin_1 81 87 PF00069 0.789
MOD_SUMO_for_1 602 605 PF00179 0.647
MOD_SUMO_rev_2 229 237 PF00179 0.682
MOD_SUMO_rev_2 238 247 PF00179 0.578
TRG_ENDOCYTIC_2 135 138 PF00928 0.608
TRG_ENDOCYTIC_2 152 155 PF00928 0.483
TRG_ENDOCYTIC_2 282 285 PF00928 0.542
TRG_ENDOCYTIC_2 322 325 PF00928 0.564
TRG_ENDOCYTIC_2 415 418 PF00928 0.535
TRG_ENDOCYTIC_2 656 659 PF00928 0.481
TRG_ER_diArg_1 17 20 PF00400 0.638
TRG_ER_diArg_1 180 183 PF00400 0.497
TRG_ER_diArg_1 368 371 PF00400 0.512
TRG_ER_diArg_1 388 391 PF00400 0.506
TRG_ER_diArg_1 485 487 PF00400 0.674
TRG_ER_diArg_1 554 556 PF00400 0.625
TRG_NLS_MonoExtC_3 388 394 PF00514 0.506
TRG_NLS_MonoExtN_4 386 393 PF00514 0.508
TRG_Pf-PMV_PEXEL_1 182 186 PF00026 0.510
TRG_Pf-PMV_PEXEL_1 241 245 PF00026 0.634
TRG_Pf-PMV_PEXEL_1 489 493 PF00026 0.621

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P597 Leptomonas seymouri 37% 100%
A0A3S7X4L3 Leishmania donovani 83% 100%
A4HJF3 Leishmania braziliensis 62% 100%
A4I6U8 Leishmania infantum 83% 100%
Q4Q691 Leishmania major 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS