Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1V4_LEIMU

TriTrypDb:

LmxM.30.1540

Length:

417

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1V4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1V4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	10	14	PF00656	0.577
CLV_NRD_NRD_1	179	181	PF00675	0.507
CLV_NRD_NRD_1	261	263	PF00675	0.614
CLV_PCSK_SKI1_1	237	241	PF00082	0.615
CLV_PCSK_SKI1_1	262	266	PF00082	0.528
DEG_SCF_FBW7_1	162	169	PF00400	0.677
DEG_SPOP_SBC_1	172	176	PF00917	0.636
DOC_CKS1_1	238	243	PF01111	0.696
DOC_CYCLIN_yCln2_LP_2	239	245	PF00134	0.621
DOC_MAPK_gen_1	408	417	PF00069	0.536
DOC_MAPK_MEF2A_6	408	417	PF00069	0.586
DOC_PP2B_LxvP_1	239	242	PF13499	0.611
DOC_PP4_FxxP_1	264	267	PF00568	0.629
DOC_USP7_MATH_1	172	176	PF00917	0.681
DOC_USP7_MATH_1	188	192	PF00917	0.506
DOC_USP7_MATH_1	219	223	PF00917	0.768
DOC_USP7_MATH_1	267	271	PF00917	0.667
DOC_USP7_MATH_1	313	317	PF00917	0.575
DOC_USP7_MATH_1	333	337	PF00917	0.460
DOC_USP7_MATH_1	355	359	PF00917	0.747
DOC_USP7_MATH_1	384	388	PF00917	0.605
DOC_WW_Pin1_4	101	106	PF00397	0.636
DOC_WW_Pin1_4	113	118	PF00397	0.684
DOC_WW_Pin1_4	158	163	PF00397	0.631
DOC_WW_Pin1_4	194	199	PF00397	0.691
DOC_WW_Pin1_4	237	242	PF00397	0.687
DOC_WW_Pin1_4	247	252	PF00397	0.779
DOC_WW_Pin1_4	294	299	PF00397	0.684
DOC_WW_Pin1_4	364	369	PF00397	0.677
DOC_WW_Pin1_4	4	9	PF00397	0.546
DOC_WW_Pin1_4	46	51	PF00397	0.616
DOC_WW_Pin1_4	52	57	PF00397	0.514
DOC_WW_Pin1_4	84	89	PF00397	0.622
LIG_14-3-3_CanoR_1	113	117	PF00244	0.650
LIG_14-3-3_CanoR_1	180	185	PF00244	0.749
LIG_14-3-3_CanoR_1	262	267	PF00244	0.530
LIG_14-3-3_CanoR_1	392	399	PF00244	0.482
LIG_14-3-3_CanoR_1	411	416	PF00244	0.502
LIG_Actin_WH2_2	314	332	PF00022	0.562
LIG_APCC_ABBAyCdc20_2	403	409	PF00400	0.497
LIG_BIR_II_1	1	5	PF00653	0.606
LIG_deltaCOP1_diTrp_1	397	405	PF00928	0.552
LIG_FHA_1	275	281	PF00498	0.602
LIG_FHA_1	284	290	PF00498	0.549
LIG_FHA_2	309	315	PF00498	0.604
LIG_FHA_2	39	45	PF00498	0.736
LIG_LIR_Apic_2	116	122	PF02991	0.730
LIG_LIR_Gen_1	165	172	PF02991	0.680
LIG_LIR_Gen_1	409	417	PF02991	0.585
LIG_LIR_Nem_3	115	121	PF02991	0.511
LIG_LIR_Nem_3	165	171	PF02991	0.679
LIG_LIR_Nem_3	409	415	PF02991	0.520
LIG_PDZ_Class_2	412	417	PF00595	0.496
LIG_Pex14_1	25	29	PF04695	0.501
LIG_REV1ctd_RIR_1	298	309	PF16727	0.486
LIG_SH2_CRK	119	123	PF00017	0.800
LIG_SH2_CRK	235	239	PF00017	0.775
LIG_SH2_CRK	245	249	PF00017	0.636
LIG_SH2_NCK_1	119	123	PF00017	0.693
LIG_SH2_SRC	245	248	PF00017	0.579
LIG_SH2_STAT5	273	276	PF00017	0.573
LIG_SH3_1	235	241	PF00018	0.732
LIG_SH3_1	245	251	PF00018	0.616
LIG_SH3_2	372	377	PF14604	0.646
LIG_SH3_3	197	203	PF00018	0.572
LIG_SH3_3	235	241	PF00018	0.698
LIG_SH3_3	245	251	PF00018	0.582
LIG_SH3_3	277	283	PF00018	0.633
LIG_SH3_3	369	375	PF00018	0.647
LIG_SH3_3	380	386	PF00018	0.592
LIG_SUMO_SIM_anti_2	277	282	PF11976	0.623
LIG_UBA3_1	57	61	PF00899	0.648
LIG_WRC_WIRS_1	309	314	PF05994	0.466
MOD_CDC14_SPxK_1	161	164	PF00782	0.615
MOD_CDK_SPxK_1	158	164	PF00069	0.597
MOD_CK1_1	111	117	PF00069	0.705
MOD_CK1_1	120	126	PF00069	0.600
MOD_CK1_1	143	149	PF00069	0.669
MOD_CK1_1	158	164	PF00069	0.480
MOD_CK1_1	183	189	PF00069	0.624
MOD_CK1_1	226	232	PF00069	0.612
MOD_CK1_1	250	256	PF00069	0.719
MOD_CK1_1	296	302	PF00069	0.605
MOD_CK1_1	308	314	PF00069	0.581
MOD_CK1_1	341	347	PF00069	0.742
MOD_CK1_1	367	373	PF00069	0.609
MOD_CK1_1	38	44	PF00069	0.634
MOD_CK1_1	52	58	PF00069	0.573
MOD_CK1_1	63	69	PF00069	0.601
MOD_DYRK1A_RPxSP_1	113	117	PF00069	0.650
MOD_GlcNHglycan	110	113	PF01048	0.708
MOD_GlcNHglycan	129	132	PF01048	0.550
MOD_GlcNHglycan	175	178	PF01048	0.720
MOD_GlcNHglycan	209	212	PF01048	0.607
MOD_GlcNHglycan	220	224	PF01048	0.588
MOD_GlcNHglycan	253	256	PF01048	0.703
MOD_GlcNHglycan	286	289	PF01048	0.675
MOD_GlcNHglycan	335	338	PF01048	0.665
MOD_GlcNHglycan	340	343	PF01048	0.666
MOD_GlcNHglycan	358	361	PF01048	0.700
MOD_GlcNHglycan	386	389	PF01048	0.627
MOD_GlcNHglycan	65	68	PF01048	0.746
MOD_GSK3_1	108	115	PF00069	0.726
MOD_GSK3_1	117	124	PF00069	0.800
MOD_GSK3_1	127	134	PF00069	0.609
MOD_GSK3_1	135	142	PF00069	0.553
MOD_GSK3_1	158	165	PF00069	0.662
MOD_GSK3_1	219	226	PF00069	0.693
MOD_GSK3_1	247	254	PF00069	0.651
MOD_GSK3_1	304	311	PF00069	0.626
MOD_GSK3_1	386	393	PF00069	0.605
MOD_GSK3_1	45	52	PF00069	0.678
MOD_GSK3_1	63	70	PF00069	0.650
MOD_GSK3_1	80	87	PF00069	0.612
MOD_N-GLC_1	140	145	PF02516	0.611
MOD_N-GLC_1	207	212	PF02516	0.728
MOD_N-GLC_1	46	51	PF02516	0.655
MOD_N-GLC_1	63	68	PF02516	0.600
MOD_NEK2_1	268	273	PF00069	0.654
MOD_NEK2_1	274	279	PF00069	0.635
MOD_NEK2_1	284	289	PF00069	0.609
MOD_NEK2_1	60	65	PF00069	0.575
MOD_PIKK_1	136	142	PF00454	0.674
MOD_PIKK_1	221	227	PF00454	0.623
MOD_PK_1	180	186	PF00069	0.657
MOD_PK_1	276	282	PF00069	0.488
MOD_PK_1	305	311	PF00069	0.470
MOD_PKA_1	180	186	PF00069	0.502
MOD_PKA_1	262	268	PF00069	0.496
MOD_PKA_1	304	310	PF00069	0.473
MOD_PKA_2	112	118	PF00069	0.654
MOD_PKA_2	155	161	PF00069	0.623
MOD_Plk_1	166	172	PF00069	0.680
MOD_Plk_1	305	311	PF00069	0.576
MOD_Plk_1	313	319	PF00069	0.570
MOD_Plk_4	269	275	PF00069	0.603
MOD_Plk_4	276	282	PF00069	0.674
MOD_Plk_4	296	302	PF00069	0.604
MOD_Plk_4	313	319	PF00069	0.551
MOD_Plk_4	86	92	PF00069	0.482
MOD_ProDKin_1	101	107	PF00069	0.639
MOD_ProDKin_1	113	119	PF00069	0.684
MOD_ProDKin_1	158	164	PF00069	0.637
MOD_ProDKin_1	194	200	PF00069	0.692
MOD_ProDKin_1	237	243	PF00069	0.690
MOD_ProDKin_1	247	253	PF00069	0.560
MOD_ProDKin_1	294	300	PF00069	0.685
MOD_ProDKin_1	364	370	PF00069	0.676
MOD_ProDKin_1	4	10	PF00069	0.547
MOD_ProDKin_1	46	52	PF00069	0.617
MOD_ProDKin_1	84	90	PF00069	0.621
TRG_ENDOCYTIC_2	20	23	PF00928	0.681

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC35	Leptomonas seymouri	26%	97%
A0A3S7X4K9	Leishmania donovani	79%	95%
A4HJD5	Leishmania braziliensis	60%	98%
A4I6T2	Leishmania infantum	78%	94%
Q4Q6A8	Leishmania major	81%	100%