Triplex capsid protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B1V2_LEIMU

TriTrypDb:

LmxM.30.1520

Length:

954

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1V2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1V2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	409	413	PF00656	0.674
CLV_C14_Caspase3-7	541	545	PF00656	0.648
CLV_NRD_NRD_1	447	449	PF00675	0.354
CLV_NRD_NRD_1	611	613	PF00675	0.420
CLV_NRD_NRD_1	633	635	PF00675	0.649
CLV_PCSK_KEX2_1	164	166	PF00082	0.300
CLV_PCSK_KEX2_1	447	449	PF00082	0.334
CLV_PCSK_KEX2_1	611	613	PF00082	0.533
CLV_PCSK_PC1ET2_1	164	166	PF00082	0.300
CLV_PCSK_SKI1_1	115	119	PF00082	0.426
CLV_PCSK_SKI1_1	196	200	PF00082	0.377
CLV_PCSK_SKI1_1	295	299	PF00082	0.541
CLV_PCSK_SKI1_1	376	380	PF00082	0.429
CLV_PCSK_SKI1_1	581	585	PF00082	0.485
CLV_PCSK_SKI1_1	85	89	PF00082	0.484
DEG_APCC_DBOX_1	114	122	PF00400	0.422
DEG_SPOP_SBC_1	772	776	PF00917	0.599
DOC_CDC14_PxL_1	215	223	PF14671	0.452
DOC_CKS1_1	35	40	PF01111	0.418
DOC_CKS1_1	485	490	PF01111	0.491
DOC_CYCLIN_RxL_1	80	91	PF00134	0.419
DOC_MAPK_DCC_7	229	237	PF00069	0.361
DOC_MAPK_gen_1	447	454	PF00069	0.348
DOC_MAPK_MEF2A_6	164	173	PF00069	0.622
DOC_MAPK_MEF2A_6	229	237	PF00069	0.375
DOC_PP2B_LxvP_1	249	252	PF13499	0.516
DOC_PP4_FxxP_1	15	18	PF00568	0.499
DOC_PP4_FxxP_1	35	38	PF00568	0.438
DOC_PP4_FxxP_1	454	457	PF00568	0.494
DOC_PP4_FxxP_1	625	628	PF00568	0.625
DOC_USP7_MATH_1	132	136	PF00917	0.464
DOC_USP7_MATH_1	252	256	PF00917	0.522
DOC_USP7_MATH_1	355	359	PF00917	0.660
DOC_USP7_MATH_1	377	381	PF00917	0.425
DOC_USP7_MATH_1	534	538	PF00917	0.733
DOC_USP7_MATH_1	714	718	PF00917	0.729
DOC_USP7_MATH_1	748	752	PF00917	0.648
DOC_USP7_MATH_1	772	776	PF00917	0.711
DOC_USP7_MATH_1	896	900	PF00917	0.762
DOC_USP7_MATH_1	911	915	PF00917	0.600
DOC_USP7_MATH_1	935	939	PF00917	0.512
DOC_USP7_UBL2_3	719	723	PF12436	0.645
DOC_WW_Pin1_4	137	142	PF00397	0.589
DOC_WW_Pin1_4	34	39	PF00397	0.387
DOC_WW_Pin1_4	360	365	PF00397	0.522
DOC_WW_Pin1_4	414	419	PF00397	0.522
DOC_WW_Pin1_4	463	468	PF00397	0.617
DOC_WW_Pin1_4	484	489	PF00397	0.641
DOC_WW_Pin1_4	676	681	PF00397	0.721
DOC_WW_Pin1_4	682	687	PF00397	0.718
DOC_WW_Pin1_4	690	695	PF00397	0.719
DOC_WW_Pin1_4	732	737	PF00397	0.641
DOC_WW_Pin1_4	815	820	PF00397	0.716
DOC_WW_Pin1_4	836	841	PF00397	0.657
DOC_WW_Pin1_4	843	848	PF00397	0.695
DOC_WW_Pin1_4	861	866	PF00397	0.618
DOC_WW_Pin1_4	898	903	PF00397	0.651
LIG_14-3-3_CanoR_1	143	153	PF00244	0.432
LIG_14-3-3_CanoR_1	376	384	PF00244	0.539
LIG_14-3-3_CanoR_1	405	409	PF00244	0.583
LIG_14-3-3_CanoR_1	470	477	PF00244	0.480
LIG_14-3-3_CanoR_1	89	97	PF00244	0.496
LIG_Actin_WH2_2	342	359	PF00022	0.340
LIG_Clathr_ClatBox_1	881	885	PF01394	0.426
LIG_EH_1	770	774	PF12763	0.484
LIG_EVH1_1	752	756	PF00568	0.645
LIG_FHA_1	126	132	PF00498	0.445
LIG_FHA_1	157	163	PF00498	0.462
LIG_FHA_1	317	323	PF00498	0.543
LIG_FHA_1	365	371	PF00498	0.520
LIG_FHA_1	373	379	PF00498	0.510
LIG_FHA_1	397	403	PF00498	0.469
LIG_FHA_1	415	421	PF00498	0.361
LIG_FHA_1	435	441	PF00498	0.636
LIG_FHA_1	466	472	PF00498	0.647
LIG_FHA_1	485	491	PF00498	0.634
LIG_FHA_1	683	689	PF00498	0.651
LIG_FHA_1	693	699	PF00498	0.554
LIG_FHA_1	772	778	PF00498	0.486
LIG_FHA_1	870	876	PF00498	0.571
LIG_FHA_1	899	905	PF00498	0.645
LIG_FHA_2	385	391	PF00498	0.439
LIG_FHA_2	399	405	PF00498	0.499
LIG_FHA_2	539	545	PF00498	0.627
LIG_FHA_2	582	588	PF00498	0.494
LIG_Integrin_RGD_1	448	450	PF01839	0.366
LIG_LIR_Apic_2	12	18	PF02991	0.455
LIG_LIR_Apic_2	32	38	PF02991	0.415
LIG_LIR_Apic_2	453	458	PF02991	0.498
LIG_LIR_Apic_2	48	53	PF02991	0.393
LIG_LIR_Apic_2	482	488	PF02991	0.455
LIG_LIR_Gen_1	147	156	PF02991	0.396
LIG_LIR_Gen_1	224	233	PF02991	0.397
LIG_LIR_Gen_1	333	343	PF02991	0.544
LIG_LIR_Gen_1	914	922	PF02991	0.583
LIG_LIR_Nem_3	110	114	PF02991	0.337
LIG_LIR_Nem_3	147	152	PF02991	0.410
LIG_LIR_Nem_3	224	228	PF02991	0.357
LIG_LIR_Nem_3	333	338	PF02991	0.572
LIG_LIR_Nem_3	616	622	PF02991	0.446
LIG_LIR_Nem_3	784	789	PF02991	0.651
LIG_LIR_Nem_3	806	810	PF02991	0.612
LIG_LIR_Nem_3	914	918	PF02991	0.429
LIG_MYND_1	680	684	PF01753	0.641
LIG_PCNA_PIPBox_1	277	286	PF02747	0.372
LIG_PCNA_yPIPBox_3	99	113	PF02747	0.430
LIG_SH2_CRK	485	489	PF00017	0.492
LIG_SH2_CRK	58	62	PF00017	0.484
LIG_SH2_CRK	619	623	PF00017	0.371
LIG_SH2_NCK_1	335	339	PF00017	0.613
LIG_SH2_NCK_1	50	54	PF00017	0.454
LIG_SH2_NCK_1	592	596	PF00017	0.476
LIG_SH2_PTP2	455	458	PF00017	0.490
LIG_SH2_PTP2	915	918	PF00017	0.567
LIG_SH2_SRC	455	458	PF00017	0.529
LIG_SH2_SRC	592	595	PF00017	0.480
LIG_SH2_STAP1	758	762	PF00017	0.483
LIG_SH2_STAT3	205	208	PF00017	0.456
LIG_SH2_STAT5	130	133	PF00017	0.509
LIG_SH2_STAT5	203	206	PF00017	0.415
LIG_SH2_STAT5	258	261	PF00017	0.480
LIG_SH2_STAT5	262	265	PF00017	0.465
LIG_SH2_STAT5	272	275	PF00017	0.509
LIG_SH2_STAT5	284	287	PF00017	0.464
LIG_SH2_STAT5	335	338	PF00017	0.614
LIG_SH2_STAT5	34	37	PF00017	0.535
LIG_SH2_STAT5	368	371	PF00017	0.459
LIG_SH2_STAT5	373	376	PF00017	0.408
LIG_SH2_STAT5	392	395	PF00017	0.308
LIG_SH2_STAT5	455	458	PF00017	0.529
LIG_SH2_STAT5	50	53	PF00017	0.251
LIG_SH2_STAT5	606	609	PF00017	0.372
LIG_SH2_STAT5	742	745	PF00017	0.624
LIG_SH2_STAT5	805	808	PF00017	0.680
LIG_SH2_STAT5	900	903	PF00017	0.718
LIG_SH2_STAT5	915	918	PF00017	0.567
LIG_SH3_3	133	139	PF00018	0.455
LIG_SH3_3	160	166	PF00018	0.469
LIG_SH3_3	213	219	PF00018	0.361
LIG_SH3_3	35	41	PF00018	0.470
LIG_SH3_3	697	703	PF00018	0.713
LIG_SH3_3	747	753	PF00018	0.613
LIG_SH3_3	8	14	PF00018	0.404
LIG_SH3_3	837	843	PF00018	0.704
LIG_SUMO_SIM_anti_2	195	201	PF11976	0.427
LIG_SUMO_SIM_anti_2	398	404	PF11976	0.450
LIG_SUMO_SIM_par_1	398	404	PF11976	0.464
LIG_SUMO_SIM_par_1	880	885	PF11976	0.422
LIG_SxIP_EBH_1	225	239	PF03271	0.330
LIG_TRAF2_2	172	177	PF00917	0.295
LIG_WRC_WIRS_1	284	289	PF05994	0.469
LIG_WRC_WIRS_1	451	456	PF05994	0.535
LIG_WRC_WIRS_1	804	809	PF05994	0.648
LIG_WW_1	755	758	PF00397	0.655
MOD_CDC14_SPxK_1	140	143	PF00782	0.531
MOD_CDK_SPK_2	360	365	PF00069	0.467
MOD_CDK_SPxK_1	137	143	PF00069	0.504
MOD_CDK_SPxxK_3	463	470	PF00069	0.481
MOD_CK1_1	333	339	PF00069	0.702
MOD_CK1_1	360	366	PF00069	0.576
MOD_CK1_1	382	388	PF00069	0.436
MOD_CK1_1	398	404	PF00069	0.465
MOD_CK1_1	459	465	PF00069	0.684
MOD_CK1_1	497	503	PF00069	0.723
MOD_CK1_1	538	544	PF00069	0.745
MOD_CK1_1	732	738	PF00069	0.630
MOD_CK1_1	761	767	PF00069	0.688
MOD_CK1_1	869	875	PF00069	0.686
MOD_CK1_1	887	893	PF00069	0.477
MOD_CK1_1	903	909	PF00069	0.530
MOD_CK1_1	927	933	PF00069	0.601
MOD_CK2_1	384	390	PF00069	0.280
MOD_CK2_1	500	506	PF00069	0.540
MOD_GlcNHglycan	146	149	PF01048	0.444
MOD_GlcNHglycan	187	190	PF01048	0.422
MOD_GlcNHglycan	19	22	PF01048	0.459
MOD_GlcNHglycan	357	360	PF01048	0.645
MOD_GlcNHglycan	437	440	PF01048	0.532
MOD_GlcNHglycan	5	8	PF01048	0.383
MOD_GlcNHglycan	512	515	PF01048	0.659
MOD_GlcNHglycan	526	531	PF01048	0.555
MOD_GlcNHglycan	537	540	PF01048	0.572
MOD_GlcNHglycan	640	643	PF01048	0.671
MOD_GlcNHglycan	66	69	PF01048	0.641
MOD_GlcNHglycan	664	667	PF01048	0.624
MOD_GlcNHglycan	731	734	PF01048	0.615
MOD_GlcNHglycan	763	766	PF01048	0.748
MOD_GSK3_1	223	230	PF00069	0.429
MOD_GSK3_1	30	37	PF00069	0.520
MOD_GSK3_1	326	333	PF00069	0.625
MOD_GSK3_1	355	362	PF00069	0.573
MOD_GSK3_1	372	379	PF00069	0.350
MOD_GSK3_1	412	419	PF00069	0.556
MOD_GSK3_1	456	463	PF00069	0.659
MOD_GSK3_1	465	472	PF00069	0.658
MOD_GSK3_1	494	501	PF00069	0.729
MOD_GSK3_1	502	509	PF00069	0.581
MOD_GSK3_1	510	517	PF00069	0.789
MOD_GSK3_1	522	529	PF00069	0.686
MOD_GSK3_1	534	541	PF00069	0.655
MOD_GSK3_1	564	571	PF00069	0.376
MOD_GSK3_1	64	71	PF00069	0.626
MOD_GSK3_1	676	683	PF00069	0.528
MOD_GSK3_1	781	788	PF00069	0.725
MOD_GSK3_1	832	839	PF00069	0.531
MOD_GSK3_1	860	867	PF00069	0.792
MOD_GSK3_1	880	887	PF00069	0.460
MOD_GSK3_1	896	903	PF00069	0.604
MOD_N-GLC_1	192	197	PF02516	0.467
MOD_N-GLC_1	360	365	PF02516	0.467
MOD_N-GLC_1	382	387	PF02516	0.548
MOD_N-GLC_1	396	401	PF02516	0.370
MOD_N-GLC_1	433	438	PF02516	0.437
MOD_N-GLC_1	497	502	PF02516	0.661
MOD_NEK2_1	221	226	PF00069	0.328
MOD_NEK2_1	469	474	PF00069	0.809
MOD_NEK2_1	564	569	PF00069	0.443
MOD_NEK2_1	715	720	PF00069	0.501
MOD_NEK2_1	729	734	PF00069	0.634
MOD_NEK2_1	773	778	PF00069	0.682
MOD_NEK2_1	785	790	PF00069	0.606
MOD_NEK2_1	803	808	PF00069	0.612
MOD_NEK2_1	88	93	PF00069	0.414
MOD_NEK2_1	925	930	PF00069	0.701
MOD_NEK2_2	223	228	PF00069	0.443
MOD_NEK2_2	758	763	PF00069	0.588
MOD_NMyristoyl	1	7	PF02799	0.417
MOD_PIKK_1	709	715	PF00454	0.736
MOD_PIKK_1	808	814	PF00454	0.710
MOD_PIKK_1	864	870	PF00454	0.763
MOD_PK_1	330	336	PF00069	0.418
MOD_PKA_1	553	559	PF00069	0.506
MOD_PKA_2	404	410	PF00069	0.556
MOD_PKA_2	460	466	PF00069	0.690
MOD_PKA_2	469	475	PF00069	0.599
MOD_PKA_2	629	635	PF00069	0.678
MOD_PKA_2	88	94	PF00069	0.560
MOD_Plk_1	192	198	PF00069	0.462
MOD_Plk_1	396	402	PF00069	0.457
MOD_Plk_1	68	74	PF00069	0.527
MOD_Plk_1	758	764	PF00069	0.609
MOD_Plk_2-3	404	410	PF00069	0.576
MOD_Plk_4	158	164	PF00069	0.401
MOD_Plk_4	30	36	PF00069	0.369
MOD_Plk_4	330	336	PF00069	0.578
MOD_Plk_4	398	404	PF00069	0.395
MOD_Plk_4	450	456	PF00069	0.536
MOD_Plk_4	564	570	PF00069	0.378
MOD_Plk_4	601	607	PF00069	0.504
MOD_Plk_4	722	728	PF00069	0.490
MOD_Plk_4	781	787	PF00069	0.751
MOD_Plk_4	803	809	PF00069	0.647
MOD_Plk_4	911	917	PF00069	0.590
MOD_Plk_4	936	942	PF00069	0.640
MOD_ProDKin_1	137	143	PF00069	0.601
MOD_ProDKin_1	34	40	PF00069	0.385
MOD_ProDKin_1	360	366	PF00069	0.511
MOD_ProDKin_1	414	420	PF00069	0.531
MOD_ProDKin_1	463	469	PF00069	0.623
MOD_ProDKin_1	484	490	PF00069	0.639
MOD_ProDKin_1	676	682	PF00069	0.724
MOD_ProDKin_1	690	696	PF00069	0.719
MOD_ProDKin_1	732	738	PF00069	0.636
MOD_ProDKin_1	815	821	PF00069	0.712
MOD_ProDKin_1	836	842	PF00069	0.653
MOD_ProDKin_1	843	849	PF00069	0.699
MOD_ProDKin_1	861	867	PF00069	0.617
MOD_ProDKin_1	898	904	PF00069	0.649
MOD_SUMO_for_1	290	293	PF00179	0.494
MOD_SUMO_rev_2	571	580	PF00179	0.374
TRG_DiLeu_BaLyEn_6	166	171	PF01217	0.453
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.421
TRG_ENDOCYTIC_2	284	287	PF00928	0.438
TRG_ENDOCYTIC_2	335	338	PF00928	0.575
TRG_ENDOCYTIC_2	592	595	PF00928	0.376
TRG_ENDOCYTIC_2	619	622	PF00928	0.372
TRG_ENDOCYTIC_2	805	808	PF00928	0.656
TRG_ENDOCYTIC_2	915	918	PF00928	0.606
TRG_ER_diArg_1	112	115	PF00400	0.431
TRG_ER_diArg_1	446	448	PF00400	0.378
TRG_ER_diArg_1	610	612	PF00400	0.498
TRG_Pf-PMV_PEXEL_1	295	299	PF00026	0.541
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.432

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBS8	Leptomonas seymouri	41%	100%
A0A1X0NQC3	Trypanosomatidae	28%	100%
A0A3S7X4H0	Leishmania donovani	87%	100%
A0A422NZA5	Trypanosoma rangeli	31%	100%
A4HJD3	Leishmania braziliensis	72%	99%
A4I6T0	Leishmania infantum	87%	100%
Q4Q6B0	Leishmania major	87%	99%
V5DGF9	Trypanosoma cruzi	31%	100%