Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1U7_LEIMU

TriTrypDb:

LmxM.30.1470

Length:

1047

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1U7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1U7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	425	429	PF00656	0.695
CLV_NRD_NRD_1	282	284	PF00675	0.699
CLV_NRD_NRD_1	36	38	PF00675	0.728
CLV_NRD_NRD_1	553	555	PF00675	0.809
CLV_NRD_NRD_1	7	9	PF00675	0.612
CLV_NRD_NRD_1	733	735	PF00675	0.761
CLV_NRD_NRD_1	805	807	PF00675	0.711
CLV_NRD_NRD_1	842	844	PF00675	0.755
CLV_PCSK_FUR_1	280	284	PF00082	0.684
CLV_PCSK_FUR_1	730	734	PF00082	0.607
CLV_PCSK_KEX2_1	282	284	PF00082	0.699
CLV_PCSK_KEX2_1	36	38	PF00082	0.728
CLV_PCSK_KEX2_1	552	554	PF00082	0.799
CLV_PCSK_KEX2_1	7	9	PF00082	0.612
CLV_PCSK_KEX2_1	732	734	PF00082	0.819
CLV_PCSK_KEX2_1	805	807	PF00082	0.711
CLV_PCSK_PC7_1	278	284	PF00082	0.709
CLV_PCSK_SKI1_1	101	105	PF00082	0.741
CLV_PCSK_SKI1_1	1041	1045	PF00082	0.536
CLV_PCSK_SKI1_1	168	172	PF00082	0.601
CLV_PCSK_SKI1_1	244	248	PF00082	0.525
CLV_PCSK_SKI1_1	585	589	PF00082	0.545
CLV_PCSK_SKI1_1	597	601	PF00082	0.795
CLV_PCSK_SKI1_1	823	827	PF00082	0.669
CLV_Separin_Metazoa	820	824	PF03568	0.674
DEG_APCC_DBOX_1	282	290	PF00400	0.697
DEG_APCC_DBOX_1	335	343	PF00400	0.680
DEG_COP1_1	81	91	PF00400	0.797
DEG_Nend_Nbox_1	1	3	PF02207	0.794
DEG_ODPH_VHL_1	468	481	PF01847	0.481
DEG_SPOP_SBC_1	105	109	PF00917	0.699
DOC_CYCLIN_RxL_1	98	108	PF00134	0.729
DOC_CYCLIN_yCln2_LP_2	386	392	PF00134	0.707
DOC_CYCLIN_yCln2_LP_2	720	726	PF00134	0.804
DOC_MAPK_JIP1_4	554	560	PF00069	0.576
DOC_PP1_RVXF_1	883	890	PF00149	0.672
DOC_PP2B_LxvP_1	685	688	PF13499	0.701
DOC_PP4_FxxP_1	313	316	PF00568	0.663
DOC_PP4_FxxP_1	492	495	PF00568	0.653
DOC_PP4_FxxP_1	790	793	PF00568	0.782
DOC_PP4_FxxP_1	896	899	PF00568	0.628
DOC_USP7_MATH_1	105	109	PF00917	0.682
DOC_USP7_MATH_1	222	226	PF00917	0.770
DOC_USP7_MATH_1	237	241	PF00917	0.626
DOC_USP7_MATH_1	305	309	PF00917	0.509
DOC_USP7_MATH_1	419	423	PF00917	0.792
DOC_USP7_MATH_1	431	435	PF00917	0.667
DOC_USP7_MATH_1	50	54	PF00917	0.766
DOC_USP7_MATH_1	512	516	PF00917	0.815
DOC_USP7_MATH_1	541	545	PF00917	0.766
DOC_USP7_MATH_1	616	620	PF00917	0.847
DOC_USP7_MATH_1	646	650	PF00917	0.744
DOC_USP7_MATH_1	661	665	PF00917	0.597
DOC_USP7_MATH_1	793	797	PF00917	0.772
DOC_USP7_MATH_1	949	953	PF00917	0.688
DOC_USP7_MATH_2	962	968	PF00917	0.607
DOC_WW_Pin1_4	115	120	PF00397	0.563
DOC_WW_Pin1_4	22	27	PF00397	0.788
DOC_WW_Pin1_4	267	272	PF00397	0.775
DOC_WW_Pin1_4	45	50	PF00397	0.732
DOC_WW_Pin1_4	470	475	PF00397	0.706
DOC_WW_Pin1_4	642	647	PF00397	0.771
DOC_WW_Pin1_4	659	664	PF00397	0.592
DOC_WW_Pin1_4	667	672	PF00397	0.663
DOC_WW_Pin1_4	68	73	PF00397	0.800
DOC_WW_Pin1_4	808	813	PF00397	0.787
DOC_WW_Pin1_4	847	852	PF00397	0.680
DOC_WW_Pin1_4	861	866	PF00397	0.592
DOC_WW_Pin1_4	868	873	PF00397	0.485
DOC_WW_Pin1_4	89	94	PF00397	0.680
DOC_WW_Pin1_4	905	910	PF00397	0.647
DOC_WW_Pin1_4	970	975	PF00397	0.783
LIG_14-3-3_CanoR_1	292	300	PF00244	0.670
LIG_14-3-3_CanoR_1	369	378	PF00244	0.767
LIG_14-3-3_CanoR_1	454	461	PF00244	0.827
LIG_14-3-3_CanoR_1	578	582	PF00244	0.657
LIG_14-3-3_CanoR_1	759	764	PF00244	0.579
LIG_14-3-3_CanoR_1	795	801	PF00244	0.814
LIG_14-3-3_CanoR_1	833	842	PF00244	0.618
LIG_14-3-3_CanoR_1	854	863	PF00244	0.761
LIG_14-3-3_CanoR_1	904	909	PF00244	0.661
LIG_14-3-3_CanoR_1	935	941	PF00244	0.528
LIG_14-3-3_CanoR_1	987	993	PF00244	0.668
LIG_Actin_WH2_2	154	170	PF00022	0.707
LIG_Actin_WH2_2	712	727	PF00022	0.779
LIG_Actin_WH2_2	963	981	PF00022	0.502
LIG_BRCT_BRCA1_1	153	157	PF00533	0.697
LIG_BRCT_BRCA1_1	907	911	PF00533	0.672
LIG_BRCT_BRCA1_1	924	928	PF00533	0.512
LIG_CtBP_PxDLS_1	439	443	PF00389	0.553
LIG_CtBP_PxDLS_1	671	675	PF00389	0.710
LIG_deltaCOP1_diTrp_1	886	896	PF00928	0.745
LIG_EH_1	326	330	PF12763	0.529
LIG_eIF4E_1	910	916	PF01652	0.600
LIG_FHA_1	1011	1017	PF00498	0.668
LIG_FHA_1	126	132	PF00498	0.541
LIG_FHA_1	150	156	PF00498	0.705
LIG_FHA_1	203	209	PF00498	0.679
LIG_FHA_1	245	251	PF00498	0.515
LIG_FHA_1	391	397	PF00498	0.600
LIG_FHA_1	4	10	PF00498	0.785
LIG_FHA_1	633	639	PF00498	0.804
LIG_FHA_1	643	649	PF00498	0.634
LIG_FHA_1	689	695	PF00498	0.590
LIG_FHA_1	895	901	PF00498	0.443
LIG_FHA_1	98	104	PF00498	0.641
LIG_FHA_2	482	488	PF00498	0.621
LIG_FHA_2	69	75	PF00498	0.798
LIG_FHA_2	704	710	PF00498	0.756
LIG_FHA_2	782	788	PF00498	0.664
LIG_FHA_2	90	96	PF00498	0.465
LIG_LIR_Apic_2	141	146	PF02991	0.749
LIG_LIR_Apic_2	19	23	PF02991	0.709
LIG_LIR_Apic_2	311	316	PF02991	0.657
LIG_LIR_Apic_2	490	495	PF02991	0.662
LIG_LIR_Apic_2	787	793	PF02991	0.753
LIG_LIR_Apic_2	907	913	PF02991	0.629
LIG_LIR_Gen_1	673	683	PF02991	0.496
LIG_LIR_Gen_1	799	808	PF02991	0.731
LIG_LIR_Gen_1	81	89	PF02991	0.803
LIG_LIR_Nem_3	154	160	PF02991	0.669
LIG_LIR_Nem_3	375	381	PF02991	0.594
LIG_LIR_Nem_3	398	403	PF02991	0.622
LIG_LIR_Nem_3	673	679	PF02991	0.496
LIG_LIR_Nem_3	706	710	PF02991	0.458
LIG_LIR_Nem_3	799	803	PF02991	0.727
LIG_LIR_Nem_3	81	85	PF02991	0.802
LIG_LIR_Nem_3	886	892	PF02991	0.742
LIG_MLH1_MIPbox_1	907	911	PF16413	0.660
LIG_MYND_1	470	474	PF01753	0.502
LIG_NRP_CendR_1	1046	1047	PF00754	0.703
LIG_Pex14_1	877	881	PF04695	0.492
LIG_Pex14_1	98	102	PF04695	0.555
LIG_Pex14_2	309	313	PF04695	0.634
LIG_SH2_CRK	1018	1022	PF00017	0.572
LIG_SH2_CRK	564	568	PF00017	0.635
LIG_SH2_CRK	676	680	PF00017	0.495
LIG_SH2_CRK	881	885	PF00017	0.476
LIG_SH2_NCK_1	143	147	PF00017	0.751
LIG_SH2_PTP2	20	23	PF00017	0.784
LIG_SH2_SRC	143	146	PF00017	0.540
LIG_SH2_SRC	20	23	PF00017	0.784
LIG_SH2_SRC	777	780	PF00017	0.657
LIG_SH2_STAP1	381	385	PF00017	0.716
LIG_SH2_STAT3	581	584	PF00017	0.699
LIG_SH2_STAT5	102	105	PF00017	0.636
LIG_SH2_STAT5	1026	1029	PF00017	0.652
LIG_SH2_STAT5	20	23	PF00017	0.784
LIG_SH2_STAT5	203	206	PF00017	0.614
LIG_SH2_STAT5	581	584	PF00017	0.699
LIG_SH2_STAT5	910	913	PF00017	0.611
LIG_SH3_1	20	26	PF00018	0.788
LIG_SH3_3	20	26	PF00018	0.788
LIG_SH3_3	325	331	PF00018	0.714
LIG_SH3_3	332	338	PF00018	0.750
LIG_SH3_3	471	477	PF00018	0.517
LIG_SH3_3	748	754	PF00018	0.742
LIG_SH3_3	807	813	PF00018	0.511
LIG_SH3_3	943	949	PF00018	0.798
LIG_SUMO_SIM_par_1	338	345	PF11976	0.662
LIG_SUMO_SIM_par_1	635	645	PF11976	0.796
LIG_SUMO_SIM_par_1	670	675	PF11976	0.700
LIG_TRAF2_1	257	260	PF00917	0.639
LIG_TRAF2_1	982	985	PF00917	0.625
LIG_TRAF2_2	271	276	PF00917	0.759
LIG_TRAF2_2	49	54	PF00917	0.698
LIG_TYR_ITIM	1016	1021	PF00017	0.566
LIG_TYR_ITIM	674	679	PF00017	0.496
LIG_TYR_ITIM	879	884	PF00017	0.483
LIG_WRC_WIRS_1	82	87	PF05994	0.729
MOD_CDK_SPK_2	115	120	PF00069	0.532
MOD_CDK_SPxxK_3	45	52	PF00069	0.821
MOD_CDK_SPxxK_3	847	854	PF00069	0.652
MOD_CK1_1	107	113	PF00069	0.731
MOD_CK1_1	159	165	PF00069	0.688
MOD_CK1_1	207	213	PF00069	0.613
MOD_CK1_1	240	246	PF00069	0.541
MOD_CK1_1	267	273	PF00069	0.838
MOD_CK1_1	345	351	PF00069	0.719
MOD_CK1_1	371	377	PF00069	0.687
MOD_CK1_1	411	417	PF00069	0.775
MOD_CK1_1	422	428	PF00069	0.752
MOD_CK1_1	464	470	PF00069	0.558
MOD_CK1_1	546	552	PF00069	0.740
MOD_CK1_1	619	625	PF00069	0.740
MOD_CK1_1	649	655	PF00069	0.766
MOD_CK1_1	659	665	PF00069	0.729
MOD_CK1_1	670	676	PF00069	0.617
MOD_CK1_1	681	687	PF00069	0.679
MOD_CK1_1	693	699	PF00069	0.732
MOD_CK1_1	741	747	PF00069	0.820
MOD_CK1_1	796	802	PF00069	0.625
MOD_CK1_1	850	856	PF00069	0.805
MOD_CK1_1	858	864	PF00069	0.734
MOD_CK1_1	983	989	PF00069	0.658
MOD_CK2_1	1000	1006	PF00069	0.632
MOD_CK2_1	138	144	PF00069	0.834
MOD_CK2_1	305	311	PF00069	0.727
MOD_CK2_1	452	458	PF00069	0.544
MOD_CK2_1	607	613	PF00069	0.831
MOD_CK2_1	68	74	PF00069	0.732
MOD_CK2_1	703	709	PF00069	0.706
MOD_CK2_1	741	747	PF00069	0.809
MOD_CK2_1	781	787	PF00069	0.660
MOD_CK2_1	978	984	PF00069	0.711
MOD_GlcNHglycan	109	112	PF01048	0.679
MOD_GlcNHglycan	212	215	PF01048	0.708
MOD_GlcNHglycan	26	29	PF01048	0.772
MOD_GlcNHglycan	319	322	PF01048	0.766
MOD_GlcNHglycan	344	347	PF01048	0.690
MOD_GlcNHglycan	371	374	PF01048	0.616
MOD_GlcNHglycan	40	43	PF01048	0.607
MOD_GlcNHglycan	417	420	PF01048	0.748
MOD_GlcNHglycan	454	457	PF01048	0.768
MOD_GlcNHglycan	527	530	PF01048	0.800
MOD_GlcNHglycan	539	542	PF01048	0.780
MOD_GlcNHglycan	589	593	PF01048	0.779
MOD_GlcNHglycan	600	603	PF01048	0.597
MOD_GlcNHglycan	618	621	PF01048	0.847
MOD_GlcNHglycan	62	65	PF01048	0.613
MOD_GlcNHglycan	658	661	PF01048	0.810
MOD_GlcNHglycan	680	683	PF01048	0.776
MOD_GlcNHglycan	688	691	PF01048	0.694
MOD_GlcNHglycan	716	719	PF01048	0.733
MOD_GlcNHglycan	795	798	PF01048	0.743
MOD_GlcNHglycan	951	954	PF01048	0.671
MOD_GlcNHglycan	966	969	PF01048	0.689
MOD_GlcNHglycan	980	983	PF01048	0.634
MOD_GSK3_1	103	110	PF00069	0.654
MOD_GSK3_1	121	128	PF00069	0.662
MOD_GSK3_1	135	142	PF00069	0.723
MOD_GSK3_1	156	163	PF00069	0.574
MOD_GSK3_1	240	247	PF00069	0.662
MOD_GSK3_1	338	345	PF00069	0.671
MOD_GSK3_1	368	375	PF00069	0.682
MOD_GSK3_1	38	45	PF00069	0.683
MOD_GSK3_1	408	415	PF00069	0.756
MOD_GSK3_1	419	426	PF00069	0.677
MOD_GSK3_1	481	488	PF00069	0.532
MOD_GSK3_1	500	507	PF00069	0.683
MOD_GSK3_1	537	544	PF00069	0.712
MOD_GSK3_1	607	614	PF00069	0.776
MOD_GSK3_1	615	622	PF00069	0.834
MOD_GSK3_1	642	649	PF00069	0.756
MOD_GSK3_1	661	668	PF00069	0.593
MOD_GSK3_1	686	693	PF00069	0.624
MOD_GSK3_1	855	862	PF00069	0.838
MOD_GSK3_1	894	901	PF00069	0.481
MOD_GSK3_1	922	929	PF00069	0.722
MOD_GSK3_1	940	947	PF00069	0.747
MOD_GSK3_1	970	977	PF00069	0.705
MOD_N-GLC_1	139	144	PF02516	0.704
MOD_N-GLC_1	530	535	PF02516	0.560
MOD_N-GLC_1	696	701	PF02516	0.644
MOD_NEK2_1	103	108	PF00069	0.739
MOD_NEK2_1	121	126	PF00069	0.524
MOD_NEK2_1	202	207	PF00069	0.615
MOD_NEK2_1	395	400	PF00069	0.560
MOD_NEK2_1	587	592	PF00069	0.671
MOD_NEK2_1	672	677	PF00069	0.789
MOD_NEK2_1	678	683	PF00069	0.688
MOD_NEK2_1	781	786	PF00069	0.745
MOD_NEK2_1	978	983	PF00069	0.775
MOD_NEK2_2	974	979	PF00069	0.496
MOD_PIKK_1	688	694	PF00454	0.523
MOD_PIKK_1	986	992	PF00454	0.668
MOD_PKA_2	305	311	PF00069	0.534
MOD_PKA_2	368	374	PF00069	0.562
MOD_PKA_2	464	470	PF00069	0.553
MOD_PKA_2	577	583	PF00069	0.653
MOD_PKA_2	741	747	PF00069	0.708
MOD_PKA_2	832	838	PF00069	0.550
MOD_PKA_2	934	940	PF00069	0.651
MOD_PKA_2	978	984	PF00069	0.614
MOD_PKA_2	986	992	PF00069	0.656
MOD_PKB_1	290	298	PF00069	0.675
MOD_Plk_1	1000	1006	PF00069	0.643
MOD_Plk_1	139	145	PF00069	0.659
MOD_Plk_1	500	506	PF00069	0.777
MOD_Plk_1	80	86	PF00069	0.803
MOD_Plk_4	1000	1006	PF00069	0.643
MOD_Plk_4	127	133	PF00069	0.727
MOD_Plk_4	156	162	PF00069	0.721
MOD_Plk_4	16	22	PF00069	0.713
MOD_Plk_4	395	401	PF00069	0.598
MOD_Plk_4	500	506	PF00069	0.704
MOD_Plk_4	577	583	PF00069	0.662
MOD_Plk_4	646	652	PF00069	0.800
MOD_Plk_4	690	696	PF00069	0.608
MOD_Plk_4	923	929	PF00069	0.724
MOD_ProDKin_1	115	121	PF00069	0.561
MOD_ProDKin_1	22	28	PF00069	0.790
MOD_ProDKin_1	267	273	PF00069	0.776
MOD_ProDKin_1	45	51	PF00069	0.730
MOD_ProDKin_1	470	476	PF00069	0.700
MOD_ProDKin_1	642	648	PF00069	0.772
MOD_ProDKin_1	659	665	PF00069	0.592
MOD_ProDKin_1	667	673	PF00069	0.663
MOD_ProDKin_1	68	74	PF00069	0.801
MOD_ProDKin_1	808	814	PF00069	0.787
MOD_ProDKin_1	847	853	PF00069	0.680
MOD_ProDKin_1	861	867	PF00069	0.592
MOD_ProDKin_1	868	874	PF00069	0.484
MOD_ProDKin_1	89	95	PF00069	0.676
MOD_ProDKin_1	905	911	PF00069	0.644
MOD_ProDKin_1	970	976	PF00069	0.782
MOD_SUMO_rev_2	117	127	PF00179	0.532
TRG_DiLeu_BaEn_1	173	178	PF01217	0.717
TRG_DiLeu_BaLyEn_6	335	340	PF01217	0.782
TRG_DiLeu_BaLyEn_6	467	472	PF01217	0.513
TRG_DiLeu_LyEn_5	173	178	PF01217	0.503
TRG_ENDOCYTIC_2	1018	1021	PF00928	0.573
TRG_ENDOCYTIC_2	1026	1029	PF00928	0.550
TRG_ENDOCYTIC_2	676	679	PF00928	0.496
TRG_ENDOCYTIC_2	881	884	PF00928	0.481
TRG_ER_diArg_1	1045	1047	PF00400	0.692
TRG_ER_diArg_1	289	292	PF00400	0.715
TRG_ER_diArg_1	35	37	PF00400	0.728
TRG_ER_diArg_1	552	554	PF00400	0.812
TRG_ER_diArg_1	7	9	PF00400	0.612
TRG_ER_diArg_1	729	732	PF00400	0.741
TRG_ER_diArg_1	903	906	PF00400	0.692

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILA0	Leptomonas seymouri	30%	100%
A0A3S7X4K1	Leishmania donovani	84%	100%
A4HJC9	Leishmania braziliensis	65%	100%
A4I6S5	Leishmania infantum	84%	100%
Q4Q6B5	Leishmania major	83%	99%