H(+)-exporting diphosphatase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Pyrophosphate-energized vacuolar membrane proton pump 1, putative

Species:

Leishmania mexicana

UniProt:

E9B1S0_LEIMU

TriTrypDb:

LmxM.30.1220

Length:

802

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 12, no: 0
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	13
GO:0110165	cellular anatomical entity	1	13
GO:0000139	Golgi membrane	5	1
GO:0000331	contractile vacuole	6	1
GO:0005773	vacuole	5	1
GO:0020022	acidocalcisome	5	1
GO:0031090	organelle membrane	3	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0097708	intracellular vesicle	5	1
GO:0098588	bounding membrane of organelle	4	1

Expansion

Sequence features

E9B1S0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1S0

Function

Biological processes
Term	Name	Level	Count
GO:0006873	intracellular monoatomic ion homeostasis	4	1
GO:0006874	intracellular calcium ion homeostasis	7	1
GO:0006875	obsolete intracellular metal ion homeostasis	6	1
GO:0006885	regulation of pH	8	1
GO:0009987	cellular process	1	1
GO:0019725	cellular homeostasis	2	1
GO:0030003	intracellular monoatomic cation homeostasis	5	1
GO:0030004	obsolete cellular monovalent inorganic cation homeostasis	6	1
GO:0030641	regulation of cellular pH	7	1
GO:0042592	homeostatic process	3	1
GO:0048878	chemical homeostasis	4	1
GO:0050801	monoatomic ion homeostasis	5	1
GO:0051452	intracellular pH reduction	9	1
GO:0051453	regulation of intracellular pH	8	1
GO:0055065	obsolete metal ion homeostasis	7	1
GO:0055067	obsolete monovalent inorganic cation homeostasis	7	1
GO:0055074	calcium ion homeostasis	8	1
GO:0055080	monoatomic cation homeostasis	6	1
GO:0055082	intracellular chemical homeostasis	3	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0072503	obsolete cellular divalent inorganic cation homeostasis	6	1
GO:0072507	obsolete divalent inorganic cation homeostasis	7	1
GO:0098771	inorganic ion homeostasis	6	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	13
GO:0004427	inorganic diphosphate phosphatase activity	6	13
GO:0005215	transporter activity	1	13
GO:0008324	monoatomic cation transmembrane transporter activity	4	13
GO:0009678	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	5	13
GO:0015075	monoatomic ion transmembrane transporter activity	3	13
GO:0015078	proton transmembrane transporter activity	5	13
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	13
GO:0015399	primary active transmembrane transporter activity	4	13
GO:0016462	pyrophosphatase activity	5	13
GO:0016787	hydrolase activity	2	13
GO:0016817	hydrolase activity, acting on acid anhydrides	3	13
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	13
GO:0022804	active transmembrane transporter activity	3	13
GO:0022853	active monoatomic ion transmembrane transporter activity	4	13
GO:0022857	transmembrane transporter activity	2	13
GO:0022890	inorganic cation transmembrane transporter activity	4	13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	561	565	PF00656	0.399
CLV_NRD_NRD_1	646	648	PF00675	0.199
CLV_NRD_NRD_1	657	659	PF00675	0.199
CLV_PCSK_KEX2_1	403	405	PF00082	0.296
CLV_PCSK_KEX2_1	646	648	PF00082	0.199
CLV_PCSK_PC1ET2_1	403	405	PF00082	0.294
CLV_PCSK_SKI1_1	404	408	PF00082	0.282
CLV_PCSK_SKI1_1	560	564	PF00082	0.199
CLV_PCSK_SKI1_1	672	676	PF00082	0.216
CLV_Separin_Metazoa	106	110	PF03568	0.399
DEG_MDM2_SWIB_1	77	85	PF02201	0.275
DEG_SCF_FBW7_1	28	34	PF00400	0.355
DOC_CDC14_PxL_1	364	372	PF14671	0.157
DOC_CKS1_1	28	33	PF01111	0.410
DOC_CYCLIN_RxL_1	401	410	PF00134	0.433
DOC_CYCLIN_yCln2_LP_2	6	12	PF00134	0.400
DOC_MAPK_DCC_7	4	12	PF00069	0.404
DOC_MAPK_DCC_7	599	607	PF00069	0.233
DOC_MAPK_HePTP_8	773	785	PF00069	0.235
DOC_MAPK_MEF2A_6	4	12	PF00069	0.531
DOC_MAPK_MEF2A_6	599	607	PF00069	0.233
DOC_MAPK_MEF2A_6	611	618	PF00069	0.233
DOC_MAPK_MEF2A_6	764	773	PF00069	0.399
DOC_MAPK_MEF2A_6	776	785	PF00069	0.235
DOC_MAPK_MEF2A_6	792	800	PF00069	0.258
DOC_PP1_RVXF_1	217	223	PF00149	0.448
DOC_PP2B_LxvP_1	6	9	PF13499	0.406
DOC_PP4_FxxP_1	649	652	PF00568	0.399
DOC_PP4_MxPP_1	678	681	PF00568	0.341
DOC_USP7_MATH_1	180	184	PF00917	0.287
DOC_USP7_MATH_1	24	28	PF00917	0.423
DOC_USP7_MATH_1	352	356	PF00917	0.199
DOC_USP7_MATH_1	387	391	PF00917	0.420
DOC_USP7_MATH_1	550	554	PF00917	0.509
DOC_USP7_MATH_1	56	60	PF00917	0.364
DOC_USP7_MATH_1	581	585	PF00917	0.235
DOC_USP7_MATH_1	595	599	PF00917	0.199
DOC_USP7_MATH_1	708	712	PF00917	0.235
DOC_USP7_UBL2_3	741	745	PF12436	0.405
DOC_WW_Pin1_4	151	156	PF00397	0.206
DOC_WW_Pin1_4	161	166	PF00397	0.175
DOC_WW_Pin1_4	27	32	PF00397	0.509
DOC_WW_Pin1_4	685	690	PF00397	0.263
DOC_WW_Pin1_4	744	749	PF00397	0.399
DOC_WW_Pin1_4	88	93	PF00397	0.470
LIG_14-3-3_CanoR_1	117	125	PF00244	0.400
LIG_14-3-3_CanoR_1	227	233	PF00244	0.406
LIG_14-3-3_CanoR_1	512	517	PF00244	0.127
LIG_14-3-3_CanoR_1	55	65	PF00244	0.362
LIG_Actin_WH2_2	83	101	PF00022	0.495
LIG_BIR_II_1	1	5	PF00653	0.488
LIG_BIR_III_4	537	541	PF00653	0.235
LIG_BIR_III_4	567	571	PF00653	0.399
LIG_BRCT_BRCA1_1	214	218	PF00533	0.389
LIG_BRCT_BRCA1_1	334	338	PF00533	0.236
LIG_BRCT_BRCA1_1	360	364	PF00533	0.130
LIG_BRCT_BRCA1_1	781	785	PF00533	0.235
LIG_EH1_1	428	436	PF00400	0.127
LIG_FHA_1	102	108	PF00498	0.465
LIG_FHA_1	121	127	PF00498	0.399
LIG_FHA_1	245	251	PF00498	0.214
LIG_FHA_1	412	418	PF00498	0.263
LIG_FHA_1	426	432	PF00498	0.219
LIG_FHA_1	481	487	PF00498	0.404
LIG_FHA_1	504	510	PF00498	0.319
LIG_FHA_1	527	533	PF00498	0.235
LIG_FHA_1	561	567	PF00498	0.432
LIG_FHA_1	571	577	PF00498	0.432
LIG_FHA_2	259	265	PF00498	0.241
LIG_FHA_2	756	762	PF00498	0.399
LIG_LIR_Gen_1	129	140	PF02991	0.388
LIG_LIR_Gen_1	172	181	PF02991	0.263
LIG_LIR_Gen_1	264	274	PF02991	0.212
LIG_LIR_Gen_1	359	370	PF02991	0.199
LIG_LIR_Gen_1	62	73	PF02991	0.159
LIG_LIR_Gen_1	86	92	PF02991	0.469
LIG_LIR_Nem_3	129	135	PF02991	0.278
LIG_LIR_Nem_3	138	143	PF02991	0.283
LIG_LIR_Nem_3	172	177	PF02991	0.263
LIG_LIR_Nem_3	264	269	PF02991	0.212
LIG_LIR_Nem_3	335	341	PF02991	0.262
LIG_LIR_Nem_3	361	367	PF02991	0.229
LIG_LIR_Nem_3	436	442	PF02991	0.222
LIG_LIR_Nem_3	464	470	PF02991	0.407
LIG_LIR_Nem_3	505	511	PF02991	0.315
LIG_LIR_Nem_3	537	542	PF02991	0.253
LIG_LIR_Nem_3	62	68	PF02991	0.223
LIG_LIR_Nem_3	76	80	PF02991	0.276
LIG_LIR_Nem_3	782	788	PF02991	0.235
LIG_LIR_Nem_3	86	90	PF02991	0.457
LIG_LYPXL_S_1	366	370	PF13949	0.399
LIG_LYPXL_yS_3	367	370	PF13949	0.199
LIG_Pex14_2	136	140	PF04695	0.235
LIG_Pex14_2	218	222	PF04695	0.387
LIG_Pex14_2	77	81	PF04695	0.247
LIG_Pex14_2	785	789	PF04695	0.282
LIG_SH2_CRK	115	119	PF00017	0.497
LIG_SH2_CRK	132	136	PF00017	0.141
LIG_SH2_CRK	467	471	PF00017	0.399
LIG_SH2_CRK	539	543	PF00017	0.399
LIG_SH2_GRB2like	196	199	PF00017	0.399
LIG_SH2_NCK_1	115	119	PF00017	0.509
LIG_SH2_NCK_1	266	270	PF00017	0.219
LIG_SH2_NCK_1	290	294	PF00017	0.408
LIG_SH2_NCK_1	699	703	PF00017	0.199
LIG_SH2_STAP1	266	270	PF00017	0.219
LIG_SH2_STAP1	290	294	PF00017	0.408
LIG_SH2_STAP1	457	461	PF00017	0.235
LIG_SH2_STAP1	462	466	PF00017	0.399
LIG_SH2_STAP1	663	667	PF00017	0.412
LIG_SH2_STAP1	83	87	PF00017	0.548
LIG_SH2_STAT3	732	735	PF00017	0.475
LIG_SH2_STAT5	112	115	PF00017	0.399
LIG_SH2_STAT5	196	199	PF00017	0.412
LIG_SH2_STAT5	254	257	PF00017	0.211
LIG_SH2_STAT5	290	293	PF00017	0.408
LIG_SH2_STAT5	457	460	PF00017	0.272
LIG_SH2_STAT5	462	465	PF00017	0.414
LIG_SH2_STAT5	493	496	PF00017	0.235
LIG_SH2_STAT5	508	511	PF00017	0.235
LIG_SH2_STAT5	596	599	PF00017	0.219
LIG_SH2_STAT5	699	702	PF00017	0.193
LIG_SH2_STAT5	732	735	PF00017	0.405
LIG_SH3_3	159	165	PF00018	0.269
LIG_SH3_3	310	316	PF00018	0.509
LIG_SH3_3	420	426	PF00018	0.309
LIG_SH3_3	493	499	PF00018	0.235
LIG_SH3_3	597	603	PF00018	0.233
LIG_SH3_3	756	762	PF00018	0.399
LIG_SH3_3	781	787	PF00018	0.235
LIG_Sin3_3	11	18	PF02671	0.453
LIG_SUMO_SIM_anti_2	414	419	PF11976	0.326
LIG_SUMO_SIM_anti_2	64	70	PF11976	0.308
LIG_SUMO_SIM_par_1	367	372	PF11976	0.199
LIG_SUMO_SIM_par_1	414	422	PF11976	0.179
LIG_SUMO_SIM_par_1	683	688	PF11976	0.277
LIG_TRAF2_1	154	157	PF00917	0.297
LIG_TRAF2_1	469	472	PF00917	0.385
LIG_TYR_ITIM	113	118	PF00017	0.509
LIG_TYR_ITIM	491	496	PF00017	0.399
LIG_UBA3_1	241	249	PF00899	0.214
LIG_UBA3_1	690	698	PF00899	0.175
LIG_WRC_WIRS_1	338	343	PF05994	0.235
MOD_CDK_SPxK_1	88	94	PF00069	0.482
MOD_CK1_1	257	263	PF00069	0.127
MOD_CK1_1	27	33	PF00069	0.418
MOD_CK1_1	528	534	PF00069	0.254
MOD_CK1_1	59	65	PF00069	0.318
MOD_CK1_1	627	633	PF00069	0.235
MOD_CK2_1	151	157	PF00069	0.297
MOD_CK2_1	258	264	PF00069	0.310
MOD_CK2_1	337	343	PF00069	0.235
MOD_Cter_Amidation	656	659	PF01082	0.309
MOD_GlcNHglycan	137	140	PF01048	0.433
MOD_GlcNHglycan	206	209	PF01048	0.266
MOD_GlcNHglycan	215	218	PF01048	0.261
MOD_GlcNHglycan	276	279	PF01048	0.184
MOD_GlcNHglycan	354	357	PF01048	0.421
MOD_GlcNHglycan	389	392	PF01048	0.206
MOD_GlcNHglycan	450	453	PF01048	0.235
MOD_GlcNHglycan	58	61	PF01048	0.477
MOD_GlcNHglycan	583	586	PF01048	0.235
MOD_GlcNHglycan	626	629	PF01048	0.242
MOD_GlcNHglycan	710	713	PF01048	0.235
MOD_GlcNHglycan	717	720	PF01048	0.235
MOD_GlcNHglycan	765	769	PF01048	0.199
MOD_GSK3_1	116	123	PF00069	0.408
MOD_GSK3_1	135	142	PF00069	0.341
MOD_GSK3_1	194	201	PF00069	0.453
MOD_GSK3_1	254	261	PF00069	0.293
MOD_GSK3_1	27	34	PF00069	0.488
MOD_GSK3_1	352	359	PF00069	0.199
MOD_GSK3_1	381	388	PF00069	0.388
MOD_GSK3_1	407	414	PF00069	0.234
MOD_GSK3_1	456	463	PF00069	0.235
MOD_GSK3_1	476	483	PF00069	0.416
MOD_GSK3_1	503	510	PF00069	0.269
MOD_GSK3_1	528	535	PF00069	0.254
MOD_GSK3_1	715	722	PF00069	0.247
MOD_N-GLC_1	167	172	PF02516	0.448
MOD_N-GLC_1	570	575	PF02516	0.199
MOD_NEK2_1	167	172	PF00069	0.309
MOD_NEK2_1	204	209	PF00069	0.509
MOD_NEK2_1	234	239	PF00069	0.241
MOD_NEK2_1	244	249	PF00069	0.224
MOD_NEK2_1	274	279	PF00069	0.235
MOD_NEK2_1	337	342	PF00069	0.243
MOD_NEK2_1	358	363	PF00069	0.229
MOD_NEK2_1	369	374	PF00069	0.190
MOD_NEK2_1	406	411	PF00069	0.235
MOD_NEK2_1	434	439	PF00069	0.310
MOD_NEK2_1	503	508	PF00069	0.236
MOD_NEK2_1	715	720	PF00069	0.365
MOD_NEK2_1	763	768	PF00069	0.399
MOD_NEK2_2	169	174	PF00069	0.219
MOD_PK_1	512	518	PF00069	0.127
MOD_PKA_2	116	122	PF00069	0.399
MOD_Plk_1	167	173	PF00069	0.248
MOD_Plk_1	257	263	PF00069	0.127
MOD_Plk_1	550	556	PF00069	0.492
MOD_Plk_2-3	258	264	PF00069	0.127
MOD_Plk_4	139	145	PF00069	0.263
MOD_Plk_4	169	175	PF00069	0.232
MOD_Plk_4	24	30	PF00069	0.366
MOD_Plk_4	411	417	PF00069	0.226
MOD_Plk_4	492	498	PF00069	0.277
MOD_Plk_4	503	509	PF00069	0.262
MOD_Plk_4	512	518	PF00069	0.298
MOD_Plk_4	583	589	PF00069	0.188
MOD_Plk_4	61	67	PF00069	0.255
MOD_Plk_4	83	89	PF00069	0.454
MOD_ProDKin_1	151	157	PF00069	0.206
MOD_ProDKin_1	161	167	PF00069	0.175
MOD_ProDKin_1	27	33	PF00069	0.510
MOD_ProDKin_1	685	691	PF00069	0.263
MOD_ProDKin_1	744	750	PF00069	0.399
MOD_ProDKin_1	88	94	PF00069	0.482
MOD_SUMO_rev_2	128	133	PF00179	0.509
TRG_DiLeu_BaLyEn_6	1	6	PF01217	0.408
TRG_DiLeu_BaLyEn_6	365	370	PF01217	0.199
TRG_ENDOCYTIC_2	115	118	PF00928	0.466
TRG_ENDOCYTIC_2	130	133	PF00928	0.231
TRG_ENDOCYTIC_2	266	269	PF00928	0.250
TRG_ENDOCYTIC_2	367	370	PF00928	0.199
TRG_ENDOCYTIC_2	467	470	PF00928	0.399
TRG_ENDOCYTIC_2	493	496	PF00928	0.255
TRG_ENDOCYTIC_2	539	542	PF00928	0.412
TRG_ER_diArg_1	645	647	PF00400	0.399
TRG_Pf-PMV_PEXEL_1	560	564	PF00026	0.208

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5A1	Leptomonas seymouri	86%	100%
A0A0S4J2L1	Bodo saltans	76%	100%
A0A1X0NPP6	Trypanosomatidae	80%	95%
A0A3Q8IEU2	Leishmania donovani	94%	100%
A0A422NED3	Trypanosoma rangeli	79%	99%
A4HJA5	Leishmania braziliensis	90%	100%
A4I6P8	Leishmania infantum	94%	100%
C9ZM75	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	97%
C9ZWU7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	97%
O68460	Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)	41%	100%
P21616	Vigna radiata var. radiata	54%	100%
P31414	Arabidopsis thaliana	54%	100%
P60363	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	38%	100%
Q06572	Hordeum vulgare	54%	100%
Q2RIS7	Moorella thermoacetica (strain ATCC 39073 / JCM 9320)	47%	100%
Q2RLE0	Moorella thermoacetica (strain ATCC 39073 / JCM 9320)	40%	100%
Q3AFC6	Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)	44%	100%
Q4Q6E1	Leishmania major	93%	100%
Q56ZN6	Arabidopsis thaliana	39%	100%
Q72Q29	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	51%	100%
Q82EJ8	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	38%	100%
Q82TF3	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	41%	100%
Q898Q9	Clostridium tetani (strain Massachusetts / E88)	46%	100%
Q89K83	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	40%	100%
Q8A294	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)	39%	100%
Q8F641	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	51%	100%
Q8G1E6	Brucella suis biovar 1 (strain 1330)	37%	100%
Q8KDT8	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	30%	100%
Q8KY01	Rhodopseudomonas palustris	40%	100%
Q8P5M6	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	39%	100%
Q8PH20	Xanthomonas axonopodis pv. citri (strain 306)	40%	100%
Q8PYZ7	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	44%	100%
Q8PYZ8	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	43%	100%
Q8RCX1	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)	40%	100%
Q8RHJ2	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	44%	100%
Q8TJA8	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	44%	100%
Q8TJA9	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	45%	100%
Q8UG67	Agrobacterium fabrum (strain C58 / ATCC 33970)	37%	100%
Q8VNW3	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)	37%	100%
Q8VRZ2	Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)	37%	100%
Q8VRZ3	Rhizobium meliloti (strain 1021)	39%	100%
Q8YGH4	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	38%	100%
Q8ZWI8	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	38%	100%
Q983A3	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	40%	100%
Q9A8J0	Caulobacter vibrioides (strain ATCC 19089 / CB15)	38%	100%
Q9FWR2	Arabidopsis thaliana	39%	100%
Q9S5X0	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	41%	100%
Q9X913	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	37%	100%
V5BFF6	Trypanosoma cruzi	79%	99%