Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B1Q5_LEIMU

TriTrypDb:

LmxM.30.1080

Length:

971

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1Q5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1Q5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.505
CLV_C14_Caspase3-7	237	241	PF00656	0.532
CLV_C14_Caspase3-7	546	550	PF00656	0.550
CLV_C14_Caspase3-7	684	688	PF00656	0.525
CLV_NRD_NRD_1	130	132	PF00675	0.637
CLV_NRD_NRD_1	136	138	PF00675	0.521
CLV_NRD_NRD_1	37	39	PF00675	0.726
CLV_NRD_NRD_1	70	72	PF00675	0.687
CLV_NRD_NRD_1	87	89	PF00675	0.480
CLV_NRD_NRD_1	95	97	PF00675	0.597
CLV_NRD_NRD_1	963	965	PF00675	0.679
CLV_NRD_NRD_1	969	971	PF00675	0.639
CLV_PCSK_KEX2_1	130	132	PF00082	0.637
CLV_PCSK_KEX2_1	135	137	PF00082	0.539
CLV_PCSK_KEX2_1	37	39	PF00082	0.764
CLV_PCSK_KEX2_1	69	71	PF00082	0.694
CLV_PCSK_KEX2_1	87	89	PF00082	0.471
CLV_PCSK_KEX2_1	95	97	PF00082	0.597
CLV_PCSK_KEX2_1	969	971	PF00082	0.694
CLV_PCSK_PC7_1	131	137	PF00082	0.538
CLV_PCSK_SKI1_1	225	229	PF00082	0.560
CLV_PCSK_SKI1_1	428	432	PF00082	0.596
CLV_PCSK_SKI1_1	493	497	PF00082	0.574
CLV_PCSK_SKI1_1	87	91	PF00082	0.550
CLV_PCSK_SKI1_1	918	922	PF00082	0.688
DEG_APCC_DBOX_1	245	253	PF00400	0.473
DEG_SPOP_SBC_1	287	291	PF00917	0.582
DEG_SPOP_SBC_1	378	382	PF00917	0.541
DEG_SPOP_SBC_1	396	400	PF00917	0.506
DEG_SPOP_SBC_1	531	535	PF00917	0.583
DEG_SPOP_SBC_1	580	584	PF00917	0.642
DEG_SPOP_SBC_1	712	716	PF00917	0.593
DEG_SPOP_SBC_1	746	750	PF00917	0.544
DEG_SPOP_SBC_1	97	101	PF00917	0.515
DOC_CKS1_1	16	21	PF01111	0.482
DOC_CKS1_1	494	499	PF01111	0.624
DOC_CYCLIN_yCln2_LP_2	491	497	PF00134	0.580
DOC_MAPK_gen_1	187	195	PF00069	0.470
DOC_MAPK_MEF2A_6	187	195	PF00069	0.515
DOC_MAPK_MEF2A_6	3	10	PF00069	0.613
DOC_PP4_FxxP_1	387	390	PF00568	0.646
DOC_PP4_FxxP_1	391	394	PF00568	0.624
DOC_PP4_FxxP_1	736	739	PF00568	0.620
DOC_PP4_FxxP_1	928	931	PF00568	0.672
DOC_PP4_MxPP_1	790	793	PF00568	0.647
DOC_USP7_MATH_1	112	116	PF00917	0.635
DOC_USP7_MATH_1	263	267	PF00917	0.647
DOC_USP7_MATH_1	272	276	PF00917	0.645
DOC_USP7_MATH_1	287	291	PF00917	0.566
DOC_USP7_MATH_1	318	322	PF00917	0.674
DOC_USP7_MATH_1	324	328	PF00917	0.637
DOC_USP7_MATH_1	36	40	PF00917	0.677
DOC_USP7_MATH_1	378	382	PF00917	0.617
DOC_USP7_MATH_1	396	400	PF00917	0.605
DOC_USP7_MATH_1	433	437	PF00917	0.661
DOC_USP7_MATH_1	441	445	PF00917	0.581
DOC_USP7_MATH_1	447	451	PF00917	0.540
DOC_USP7_MATH_1	478	482	PF00917	0.553
DOC_USP7_MATH_1	484	488	PF00917	0.616
DOC_USP7_MATH_1	512	516	PF00917	0.532
DOC_USP7_MATH_1	547	551	PF00917	0.664
DOC_USP7_MATH_1	623	627	PF00917	0.560
DOC_USP7_MATH_1	653	657	PF00917	0.620
DOC_USP7_MATH_1	658	662	PF00917	0.650
DOC_USP7_MATH_1	667	671	PF00917	0.569
DOC_USP7_MATH_1	676	680	PF00917	0.540
DOC_USP7_MATH_1	712	716	PF00917	0.602
DOC_USP7_MATH_1	717	721	PF00917	0.631
DOC_USP7_MATH_1	723	727	PF00917	0.564
DOC_USP7_MATH_1	730	734	PF00917	0.514
DOC_USP7_MATH_1	747	751	PF00917	0.537
DOC_USP7_MATH_1	818	822	PF00917	0.542
DOC_USP7_MATH_1	864	868	PF00917	0.658
DOC_USP7_MATH_1	869	873	PF00917	0.628
DOC_USP7_MATH_1	911	915	PF00917	0.678
DOC_USP7_MATH_1	916	920	PF00917	0.654
DOC_USP7_MATH_1	97	101	PF00917	0.589
DOC_USP7_UBL2_3	355	359	PF12436	0.607
DOC_WW_Pin1_4	15	20	PF00397	0.531
DOC_WW_Pin1_4	261	266	PF00397	0.616
DOC_WW_Pin1_4	270	275	PF00397	0.663
DOC_WW_Pin1_4	277	282	PF00397	0.602
DOC_WW_Pin1_4	316	321	PF00397	0.654
DOC_WW_Pin1_4	322	327	PF00397	0.683
DOC_WW_Pin1_4	390	395	PF00397	0.650
DOC_WW_Pin1_4	429	434	PF00397	0.528
DOC_WW_Pin1_4	493	498	PF00397	0.630
DOC_WW_Pin1_4	519	524	PF00397	0.651
DOC_WW_Pin1_4	621	626	PF00397	0.692
DOC_WW_Pin1_4	647	652	PF00397	0.648
DOC_WW_Pin1_4	831	836	PF00397	0.550
DOC_WW_Pin1_4	906	911	PF00397	0.698
DOC_WW_Pin1_4	932	937	PF00397	0.678
LIG_14-3-3_CanoR_1	37	43	PF00244	0.721
LIG_14-3-3_CanoR_1	95	104	PF00244	0.641
LIG_BIR_II_1	1	5	PF00653	0.627
LIG_BRCT_BRCA1_1	145	149	PF00533	0.528
LIG_BRCT_BRCA1_1	290	294	PF00533	0.639
LIG_BRCT_BRCA1_1	484	488	PF00533	0.676
LIG_BRCT_BRCA1_1	585	589	PF00533	0.548
LIG_BRCT_BRCA1_1	610	614	PF00533	0.641
LIG_BRCT_BRCA1_1	693	697	PF00533	0.656
LIG_BRCT_BRCA1_1	714	718	PF00533	0.687
LIG_BRCT_BRCA1_1	732	736	PF00533	0.520
LIG_BRCT_BRCA1_1	765	769	PF00533	0.707
LIG_BRCT_BRCA1_1	840	844	PF00533	0.593
LIG_BRCT_BRCA1_1	861	865	PF00533	0.686
LIG_BRCT_BRCA1_1	934	938	PF00533	0.677
LIG_EH_1	388	392	PF12763	0.659
LIG_EH_1	402	406	PF12763	0.581
LIG_EH_1	540	544	PF12763	0.693
LIG_FHA_1	165	171	PF00498	0.513
LIG_FHA_1	339	345	PF00498	0.572
LIG_FHA_1	411	417	PF00498	0.572
LIG_FHA_1	453	459	PF00498	0.572
LIG_FHA_1	466	472	PF00498	0.647
LIG_FHA_1	953	959	PF00498	0.678
LIG_FHA_2	111	117	PF00498	0.615
LIG_FHA_2	184	190	PF00498	0.461
LIG_FHA_2	366	372	PF00498	0.648
LIG_FHA_2	544	550	PF00498	0.543
LIG_LIR_Apic_2	386	390	PF02991	0.640
LIG_LIR_Apic_2	733	739	PF02991	0.621
LIG_LIR_Gen_1	197	206	PF02991	0.660
LIG_LIR_Gen_1	485	495	PF02991	0.642
LIG_LIR_Nem_3	11	16	PF02991	0.622
LIG_LIR_Nem_3	197	202	PF02991	0.663
LIG_LIR_Nem_3	485	491	PF02991	0.641
LIG_LIR_Nem_3	611	617	PF02991	0.643
LIG_PCNA_yPIPBox_3	153	166	PF02747	0.506
LIG_Pex14_2	304	308	PF04695	0.504
LIG_Pex14_2	387	391	PF04695	0.648
LIG_Pex14_2	736	740	PF04695	0.624
LIG_SH2_CRK	199	203	PF00017	0.525
LIG_SH2_NCK_1	199	203	PF00017	0.514
LIG_SH2_STAP1	199	203	PF00017	0.514
LIG_SH3_3	275	281	PF00018	0.651
LIG_SH3_3	28	34	PF00018	0.736
LIG_SH3_3	455	461	PF00018	0.532
LIG_SH3_3	491	497	PF00018	0.636
LIG_SH3_3	539	545	PF00018	0.689
LIG_SH3_3	550	556	PF00018	0.597
LIG_SH3_3	614	620	PF00018	0.687
LIG_SH3_3	630	636	PF00018	0.554
LIG_SH3_3	789	795	PF00018	0.643
LIG_SH3_4	355	362	PF00018	0.611
LIG_SUMO_SIM_anti_2	98	111	PF11976	0.663
MOD_CK1_1	164	170	PF00069	0.372
MOD_CK1_1	201	207	PF00069	0.499
MOD_CK1_1	261	267	PF00069	0.599
MOD_CK1_1	273	279	PF00069	0.651
MOD_CK1_1	289	295	PF00069	0.544
MOD_CK1_1	307	313	PF00069	0.503
MOD_CK1_1	319	325	PF00069	0.581
MOD_CK1_1	327	333	PF00069	0.551
MOD_CK1_1	337	343	PF00069	0.536
MOD_CK1_1	376	382	PF00069	0.695
MOD_CK1_1	392	398	PF00069	0.556
MOD_CK1_1	399	405	PF00069	0.537
MOD_CK1_1	4	10	PF00069	0.609
MOD_CK1_1	410	416	PF00069	0.570
MOD_CK1_1	432	438	PF00069	0.645
MOD_CK1_1	48	54	PF00069	0.635
MOD_CK1_1	503	509	PF00069	0.658
MOD_CK1_1	515	521	PF00069	0.560
MOD_CK1_1	522	528	PF00069	0.513
MOD_CK1_1	576	582	PF00069	0.695
MOD_CK1_1	606	612	PF00069	0.584
MOD_CK1_1	638	644	PF00069	0.706
MOD_CK1_1	661	667	PF00069	0.675
MOD_CK1_1	670	676	PF00069	0.596
MOD_CK1_1	696	702	PF00069	0.657
MOD_CK1_1	731	737	PF00069	0.649
MOD_CK1_1	821	827	PF00069	0.626
MOD_CK1_1	829	835	PF00069	0.683
MOD_CK1_1	859	865	PF00069	0.684
MOD_CK1_1	867	873	PF00069	0.605
MOD_CK1_1	914	920	PF00069	0.629
MOD_CK1_1	952	958	PF00069	0.679
MOD_CK1_1	960	966	PF00069	0.613
MOD_CK1_1	99	105	PF00069	0.687
MOD_CK2_1	110	116	PF00069	0.591
MOD_CK2_1	183	189	PF00069	0.572
MOD_CK2_1	191	197	PF00069	0.540
MOD_CK2_1	215	221	PF00069	0.518
MOD_CK2_1	365	371	PF00069	0.650
MOD_CK2_1	451	457	PF00069	0.576
MOD_GlcNHglycan	210	213	PF01048	0.482
MOD_GlcNHglycan	309	312	PF01048	0.625
MOD_GlcNHglycan	314	317	PF01048	0.618
MOD_GlcNHglycan	326	329	PF01048	0.555
MOD_GlcNHglycan	394	397	PF01048	0.551
MOD_GlcNHglycan	409	412	PF01048	0.597
MOD_GlcNHglycan	435	438	PF01048	0.630
MOD_GlcNHglycan	449	452	PF01048	0.565
MOD_GlcNHglycan	480	483	PF01048	0.611
MOD_GlcNHglycan	502	505	PF01048	0.694
MOD_GlcNHglycan	519	522	PF01048	0.520
MOD_GlcNHglycan	527	530	PF01048	0.572
MOD_GlcNHglycan	534	537	PF01048	0.537
MOD_GlcNHglycan	575	578	PF01048	0.661
MOD_GlcNHglycan	58	61	PF01048	0.526
MOD_GlcNHglycan	600	603	PF01048	0.672
MOD_GlcNHglycan	605	608	PF01048	0.610
MOD_GlcNHglycan	611	614	PF01048	0.514
MOD_GlcNHglycan	621	624	PF01048	0.519
MOD_GlcNHglycan	655	658	PF01048	0.625
MOD_GlcNHglycan	669	672	PF01048	0.594
MOD_GlcNHglycan	674	677	PF01048	0.539
MOD_GlcNHglycan	678	681	PF01048	0.608
MOD_GlcNHglycan	715	718	PF01048	0.616
MOD_GlcNHglycan	730	733	PF01048	0.589
MOD_GlcNHglycan	736	739	PF01048	0.586
MOD_GlcNHglycan	749	752	PF01048	0.539
MOD_GlcNHglycan	765	768	PF01048	0.562
MOD_GlcNHglycan	816	819	PF01048	0.639
MOD_GlcNHglycan	820	823	PF01048	0.609
MOD_GlcNHglycan	828	831	PF01048	0.604
MOD_GlcNHglycan	846	849	PF01048	0.531
MOD_GlcNHglycan	858	861	PF01048	0.569
MOD_GlcNHglycan	880	883	PF01048	0.685
MOD_GlcNHglycan	913	916	PF01048	0.632
MOD_GlcNHglycan	918	921	PF01048	0.602
MOD_GSK3_1	110	117	PF00069	0.702
MOD_GSK3_1	143	150	PF00069	0.526
MOD_GSK3_1	15	22	PF00069	0.483
MOD_GSK3_1	161	168	PF00069	0.353
MOD_GSK3_1	179	186	PF00069	0.443
MOD_GSK3_1	204	211	PF00069	0.468
MOD_GSK3_1	234	241	PF00069	0.543
MOD_GSK3_1	270	277	PF00069	0.665
MOD_GSK3_1	303	310	PF00069	0.660
MOD_GSK3_1	312	319	PF00069	0.605
MOD_GSK3_1	322	329	PF00069	0.525
MOD_GSK3_1	330	337	PF00069	0.572
MOD_GSK3_1	365	372	PF00069	0.674
MOD_GSK3_1	373	380	PF00069	0.644
MOD_GSK3_1	392	399	PF00069	0.523
MOD_GSK3_1	403	410	PF00069	0.600
MOD_GSK3_1	428	435	PF00069	0.671
MOD_GSK3_1	447	454	PF00069	0.515
MOD_GSK3_1	478	485	PF00069	0.665
MOD_GSK3_1	48	55	PF00069	0.722
MOD_GSK3_1	496	503	PF00069	0.524
MOD_GSK3_1	512	519	PF00069	0.542
MOD_GSK3_1	525	532	PF00069	0.578
MOD_GSK3_1	543	550	PF00069	0.540
MOD_GSK3_1	572	579	PF00069	0.693
MOD_GSK3_1	580	587	PF00069	0.639
MOD_GSK3_1	603	610	PF00069	0.596
MOD_GSK3_1	61	68	PF00069	0.606
MOD_GSK3_1	615	622	PF00069	0.515
MOD_GSK3_1	635	642	PF00069	0.556
MOD_GSK3_1	658	665	PF00069	0.680
MOD_GSK3_1	670	677	PF00069	0.567
MOD_GSK3_1	692	699	PF00069	0.649
MOD_GSK3_1	703	710	PF00069	0.620
MOD_GSK3_1	713	720	PF00069	0.650
MOD_GSK3_1	724	731	PF00069	0.567
MOD_GSK3_1	745	752	PF00069	0.631
MOD_GSK3_1	814	821	PF00069	0.599
MOD_GSK3_1	822	829	PF00069	0.589
MOD_GSK3_1	834	841	PF00069	0.581
MOD_GSK3_1	867	874	PF00069	0.599
MOD_GSK3_1	91	98	PF00069	0.523
MOD_GSK3_1	948	955	PF00069	0.676
MOD_N-GLC_1	191	196	PF02516	0.459
MOD_N-GLC_1	316	321	PF02516	0.582
MOD_N-GLC_1	373	378	PF02516	0.636
MOD_N-GLC_1	45	50	PF02516	0.687
MOD_N-GLC_1	603	608	PF02516	0.606
MOD_N-GLC_1	647	652	PF02516	0.644
MOD_N-GLC_1	691	696	PF02516	0.671
MOD_N-GLC_1	703	708	PF02516	0.612
MOD_N-GLC_1	856	861	PF02516	0.680
MOD_N-GLC_1	867	872	PF02516	0.579
MOD_N-GLC_2	299	301	PF02516	0.629
MOD_NEK2_1	1	6	PF00069	0.672
MOD_NEK2_1	165	170	PF00069	0.520
MOD_NEK2_1	191	196	PF00069	0.529
MOD_NEK2_1	206	211	PF00069	0.536
MOD_NEK2_1	227	232	PF00069	0.578
MOD_NEK2_1	335	340	PF00069	0.648
MOD_NEK2_1	347	352	PF00069	0.601
MOD_NEK2_1	407	412	PF00069	0.674
MOD_NEK2_1	524	529	PF00069	0.643
MOD_NEK2_1	558	563	PF00069	0.564
MOD_NEK2_1	639	644	PF00069	0.707
MOD_NEK2_1	681	686	PF00069	0.589
MOD_NEK2_1	697	702	PF00069	0.607
MOD_NEK2_1	713	718	PF00069	0.580
MOD_NEK2_1	814	819	PF00069	0.604
MOD_NEK2_1	844	849	PF00069	0.651
MOD_NEK2_1	856	861	PF00069	0.578
MOD_NEK2_1	878	883	PF00069	0.655
MOD_NEK2_1	948	953	PF00069	0.628
MOD_NEK2_1	958	963	PF00069	0.650
MOD_NEK2_2	839	844	PF00069	0.594
MOD_PIKK_1	1	7	PF00454	0.621
MOD_PIKK_1	496	502	PF00454	0.566
MOD_PIKK_1	561	567	PF00454	0.606
MOD_PIKK_1	639	645	PF00454	0.595
MOD_PIKK_1	949	955	PF00454	0.632
MOD_PK_1	198	204	PF00069	0.457
MOD_PKA_1	37	43	PF00069	0.608
MOD_PKA_1	95	101	PF00069	0.517
MOD_PKA_2	102	108	PF00069	0.642
MOD_PKA_2	238	244	PF00069	0.567
MOD_PKA_2	36	42	PF00069	0.700
MOD_PKA_2	95	101	PF00069	0.614
MOD_PKB_1	135	143	PF00069	0.461
MOD_PKB_1	71	79	PF00069	0.576
MOD_Plk_1	191	197	PF00069	0.520
MOD_Plk_1	215	221	PF00069	0.577
MOD_Plk_1	51	57	PF00069	0.621
MOD_Plk_1	73	79	PF00069	0.552
MOD_Plk_4	102	108	PF00069	0.742
MOD_Plk_4	198	204	PF00069	0.524
MOD_Plk_4	238	244	PF00069	0.513
MOD_Plk_4	731	737	PF00069	0.524
MOD_Plk_4	839	845	PF00069	0.697
MOD_Plk_4	874	880	PF00069	0.687
MOD_Plk_4	953	959	PF00069	0.685
MOD_ProDKin_1	15	21	PF00069	0.532
MOD_ProDKin_1	261	267	PF00069	0.618
MOD_ProDKin_1	270	276	PF00069	0.664
MOD_ProDKin_1	277	283	PF00069	0.602
MOD_ProDKin_1	316	322	PF00069	0.653
MOD_ProDKin_1	390	396	PF00069	0.650
MOD_ProDKin_1	429	435	PF00069	0.528
MOD_ProDKin_1	493	499	PF00069	0.631
MOD_ProDKin_1	519	525	PF00069	0.652
MOD_ProDKin_1	621	627	PF00069	0.694
MOD_ProDKin_1	647	653	PF00069	0.641
MOD_ProDKin_1	831	837	PF00069	0.552
MOD_ProDKin_1	906	912	PF00069	0.698
MOD_ProDKin_1	932	938	PF00069	0.679
MOD_SUMO_for_1	107	110	PF00179	0.634
MOD_SUMO_for_1	250	253	PF00179	0.486
MOD_SUMO_rev_2	230	237	PF00179	0.575
MOD_SUMO_rev_2	454	461	PF00179	0.576
TRG_DiLeu_BaEn_4	215	221	PF01217	0.518
TRG_ENDOCYTIC_2	199	202	PF00928	0.524
TRG_ENDOCYTIC_2	203	206	PF00928	0.488
TRG_ER_diArg_1	134	137	PF00400	0.584
TRG_ER_diArg_1	29	32	PF00400	0.684
TRG_ER_diArg_1	36	38	PF00400	0.643
TRG_ER_diArg_1	69	71	PF00400	0.677
TRG_ER_diArg_1	95	97	PF00400	0.651
TRG_ER_diArg_1	968	970	PF00400	0.682
TRG_NES_CRM1_1	183	197	PF08389	0.513
TRG_NLS_MonoExtC_3	963	968	PF00514	0.677
TRG_Pf-PMV_PEXEL_1	153	158	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	88	93	PF00026	0.622

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4C6	Leishmania donovani	83%	99%
A4HJ89	Leishmania braziliensis	65%	98%
A4I6N2	Leishmania infantum	82%	99%
Q4Q6F5	Leishmania major	82%	99%