Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1Q2_LEIMU

TriTrypDb:

LmxM.30.1050

Length:

383

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1Q2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1Q2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	364	368	PF00656	0.671
CLV_NRD_NRD_1	198	200	PF00675	0.750
CLV_NRD_NRD_1	209	211	PF00675	0.708
CLV_NRD_NRD_1	257	259	PF00675	0.712
CLV_PCSK_FUR_1	195	199	PF00082	0.670
CLV_PCSK_KEX2_1	195	197	PF00082	0.730
CLV_PCSK_KEX2_1	198	200	PF00082	0.714
CLV_PCSK_KEX2_1	209	211	PF00082	0.671
CLV_PCSK_SKI1_1	280	284	PF00082	0.657
DOC_CKS1_1	8	13	PF01111	0.643
DOC_CYCLIN_yCln2_LP_2	140	146	PF00134	0.531
DOC_CYCLIN_yCln2_LP_2	8	14	PF00134	0.505
DOC_MAPK_gen_1	223	233	PF00069	0.608
DOC_PP1_RVXF_1	69	75	PF00149	0.535
DOC_PP2B_LxvP_1	345	348	PF13499	0.679
DOC_USP7_MATH_1	211	215	PF00917	0.542
DOC_USP7_MATH_1	249	253	PF00917	0.682
DOC_USP7_MATH_1	307	311	PF00917	0.766
DOC_USP7_MATH_1	51	55	PF00917	0.679
DOC_USP7_MATH_1	78	82	PF00917	0.645
DOC_USP7_UBL2_3	274	278	PF12436	0.682
DOC_USP7_UBL2_3	280	284	PF12436	0.581
DOC_WW_Pin1_4	7	12	PF00397	0.755
LIG_BIR_II_1	1	5	PF00653	0.768
LIG_BIR_III_4	367	371	PF00653	0.556
LIG_FHA_1	336	342	PF00498	0.681
LIG_FHA_1	59	65	PF00498	0.625
LIG_FHA_1	67	73	PF00498	0.514
LIG_FHA_2	115	121	PF00498	0.474
LIG_FHA_2	235	241	PF00498	0.679
LIG_FHA_2	298	304	PF00498	0.546
LIG_FHA_2	8	14	PF00498	0.643
LIG_LIR_Gen_1	121	130	PF02991	0.468
LIG_LIR_Nem_3	121	127	PF02991	0.470
LIG_PDZ_Class_1	378	383	PF00595	0.672
LIG_SH3_3	156	162	PF00018	0.646
LIG_SH3_3	93	99	PF00018	0.674
LIG_SH3_4	280	287	PF00018	0.658
LIG_TRAF2_1	118	121	PF00917	0.463
LIG_UBA3_1	123	131	PF00899	0.469
MOD_CK1_1	234	240	PF00069	0.680
MOD_CK1_1	253	259	PF00069	0.692
MOD_CK1_1	54	60	PF00069	0.677
MOD_CK1_1	65	71	PF00069	0.704
MOD_CK2_1	114	120	PF00069	0.649
MOD_CK2_1	234	240	PF00069	0.679
MOD_CK2_1	249	255	PF00069	0.545
MOD_CK2_1	297	303	PF00069	0.545
MOD_CK2_1	307	313	PF00069	0.690
MOD_CK2_1	343	349	PF00069	0.559
MOD_CK2_1	35	41	PF00069	0.652
MOD_CK2_1	7	13	PF00069	0.756
MOD_Cter_Amidation	154	157	PF01082	0.655
MOD_Cter_Amidation	207	210	PF01082	0.693
MOD_GlcNHglycan	1	4	PF01048	0.763
MOD_GlcNHglycan	107	110	PF01048	0.701
MOD_GlcNHglycan	117	120	PF01048	0.540
MOD_GlcNHglycan	132	135	PF01048	0.491
MOD_GlcNHglycan	184	187	PF01048	0.787
MOD_GlcNHglycan	201	204	PF01048	0.542
MOD_GlcNHglycan	255	258	PF01048	0.678
MOD_GlcNHglycan	300	303	PF01048	0.724
MOD_GlcNHglycan	344	348	PF01048	0.689
MOD_GlcNHglycan	37	40	PF01048	0.649
MOD_GlcNHglycan	80	83	PF01048	0.548
MOD_GSK3_1	175	182	PF00069	0.671
MOD_GSK3_1	249	256	PF00069	0.754
MOD_GSK3_1	293	300	PF00069	0.707
MOD_GSK3_1	33	40	PF00069	0.654
MOD_GSK3_1	54	61	PF00069	0.688
MOD_GSK3_1	62	69	PF00069	0.585
MOD_LATS_1	60	66	PF00433	0.636
MOD_N-GLC_1	182	187	PF02516	0.562
MOD_N-GLC_1	199	204	PF02516	0.513
MOD_N-GLC_1	297	302	PF02516	0.543
MOD_NEK2_1	125	130	PF00069	0.469
MOD_NEK2_1	35	40	PF00069	0.690
MOD_NEK2_1	58	63	PF00069	0.596
MOD_NEK2_1	72	77	PF00069	0.526
MOD_PIKK_1	211	217	PF00454	0.669
MOD_PIKK_1	234	240	PF00454	0.679
MOD_PIKK_1	307	313	PF00454	0.690
MOD_PKA_1	258	264	PF00069	0.657
MOD_PKA_2	103	109	PF00069	0.682
MOD_PKA_2	125	131	PF00069	0.479
MOD_PKA_2	65	71	PF00069	0.719
MOD_PKB_1	197	205	PF00069	0.539
MOD_Plk_1	146	152	PF00069	0.632
MOD_Plk_4	146	152	PF00069	0.601
MOD_Plk_4	54	60	PF00069	0.554
MOD_ProDKin_1	7	13	PF00069	0.756
MOD_SUMO_rev_2	118	124	PF00179	0.595
MOD_SUMO_rev_2	324	333	PF00179	0.639
MOD_SUMO_rev_2	7	17	PF00179	0.504
TRG_DiLeu_BaEn_2	119	125	PF01217	0.464
TRG_ENDOCYTIC_2	92	95	PF00928	0.536
TRG_ER_diArg_1	102	105	PF00400	0.656
TRG_ER_diArg_1	194	197	PF00400	0.688
TRG_ER_diArg_1	209	211	PF00400	0.667
TRG_ER_KDEL_1	380	383	PF00810	0.667
TRG_NLS_MonoExtC_3	155	160	PF00514	0.649
TRG_NLS_MonoExtN_4	154	160	PF00514	0.588

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJY9	Leishmania donovani	73%	100%
A4HJ85	Leishmania braziliensis	35%	100%
A4I6M9	Leishmania infantum	74%	100%
Q4Q6F8	Leishmania major	71%	100%