LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

UPF0325 protein YaeH

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
UPF0325 protein YaeH
Gene product:
KIAA1430 homologue, putative
Species:
Leishmania mexicana
UniProt:
E9B1P0_LEIMU
TriTrypDb:
LmxM.30.0890
Length:
158

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1P0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1P0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 100 102 PF00675 0.418
CLV_NRD_NRD_1 136 138 PF00675 0.651
CLV_PCSK_KEX2_1 135 137 PF00082 0.637
CLV_PCSK_KEX2_1 4 6 PF00082 0.726
CLV_PCSK_KEX2_1 99 101 PF00082 0.417
CLV_PCSK_PC1ET2_1 4 6 PF00082 0.726
DEG_Nend_UBRbox_2 1 3 PF02207 0.762
DOC_USP7_MATH_1 143 147 PF00917 0.628
DOC_USP7_MATH_1 3 7 PF00917 0.730
DOC_USP7_MATH_1 94 98 PF00917 0.470
DOC_USP7_UBL2_3 67 71 PF12436 0.497
DOC_WW_Pin1_4 35 40 PF00397 0.375
LIG_14-3-3_CterR_2 155 158 PF00244 0.614
LIG_BRCT_BRCA1_1 127 131 PF00533 0.626
LIG_LIR_Apic_2 41 47 PF02991 0.530
LIG_LIR_Gen_1 40 48 PF02991 0.525
LIG_LIR_Nem_3 40 45 PF02991 0.525
LIG_LIR_Nem_3 85 91 PF02991 0.510
LIG_PCNA_yPIPBox_3 63 73 PF02747 0.497
LIG_SH2_CRK 42 46 PF00017 0.469
LIG_SH2_PTP2 44 47 PF00017 0.530
LIG_SH2_SRC 42 45 PF00017 0.355
LIG_SH2_STAT3 148 151 PF00017 0.632
LIG_SH2_STAT5 44 47 PF00017 0.530
LIG_SH3_3 146 152 PF00018 0.600
LIG_SH3_5 87 91 PF00018 0.335
LIG_TRAF2_2 149 154 PF00917 0.638
MOD_GlcNHglycan 5 8 PF01048 0.747
MOD_N-GLC_1 35 40 PF02516 0.375
MOD_NEK2_1 119 124 PF00069 0.530
MOD_NEK2_1 153 158 PF00069 0.757
MOD_NEK2_2 47 52 PF00069 0.530
MOD_PIKK_1 119 125 PF00454 0.510
MOD_PIKK_1 94 100 PF00454 0.497
MOD_PKA_2 143 149 PF00069 0.572
MOD_ProDKin_1 35 41 PF00069 0.375
TRG_DiLeu_BaEn_1 111 116 PF01217 0.406
TRG_ENDOCYTIC_2 150 153 PF00928 0.608
TRG_ENDOCYTIC_2 42 45 PF00928 0.454
TRG_ER_diArg_1 135 137 PF00400 0.685
TRG_ER_diArg_1 99 101 PF00400 0.444
TRG_Pf-PMV_PEXEL_1 101 105 PF00026 0.238

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVY5 Leptomonas seymouri 70% 100%
A0A0S4KEZ6 Bodo saltans 31% 88%
A0A1X0P942 Trypanosomatidae 43% 98%
A0A3R7RG32 Trypanosoma rangeli 41% 98%
A0A3S7X489 Leishmania donovani 90% 100%
A4HJ64 Leishmania braziliensis 78% 100%
A4I6L5 Leishmania infantum 90% 100%
D0A361 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 98%
Q9BHH0 Leishmania major 89% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS