LeishMANIAdb
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Rho-GAP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Rho-GAP domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B1N4_LEIMU
TriTrypDb:
LmxM.30.0820
Length:
123

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1N4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1N4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.470
CLV_NRD_NRD_1 4 6 PF00675 0.750
CLV_NRD_NRD_1 43 45 PF00675 0.447
CLV_PCSK_KEX2_1 103 105 PF00082 0.481
CLV_PCSK_KEX2_1 43 45 PF00082 0.447
CLV_PCSK_PC1ET2_1 103 105 PF00082 0.481
CLV_PCSK_PC7_1 39 45 PF00082 0.431
DOC_MAPK_gen_1 5 13 PF00069 0.732
DOC_PP4_FxxP_1 25 28 PF00568 0.654
DOC_USP7_MATH_1 111 115 PF00917 0.572
LIG_BRCT_BRCA1_1 17 21 PF00533 0.472
LIG_FHA_1 85 91 PF00498 0.394
LIG_LIR_Apic_2 23 28 PF02991 0.640
LIG_LIR_Gen_1 114 119 PF02991 0.494
LIG_LIR_Nem_3 114 118 PF02991 0.493
LIG_LIR_Nem_3 18 24 PF02991 0.480
LIG_PCNA_PIPBox_1 57 66 PF02747 0.621
LIG_PCNA_yPIPBox_3 57 67 PF02747 0.608
LIG_PDZ_Class_1 118 123 PF00595 0.515
LIG_Pex14_2 21 25 PF04695 0.459
LIG_PTB_Apo_2 7 14 PF02174 0.725
LIG_SH2_CRK 61 65 PF00017 0.603
LIG_SH2_STAT5 45 48 PF00017 0.465
LIG_SH3_3 107 113 PF00018 0.513
MOD_CK1_1 114 120 PF00069 0.550
MOD_GlcNHglycan 16 20 PF01048 0.471
MOD_GSK3_1 114 121 PF00069 0.621
MOD_PKA_2 4 10 PF00069 0.582
MOD_Plk_1 84 90 PF00069 0.390
MOD_Plk_4 114 120 PF00069 0.496
MOD_Plk_4 20 26 PF00069 0.478
MOD_SUMO_rev_2 99 105 PF00179 0.470
TRG_DiLeu_BaEn_1 85 90 PF01217 0.621
TRG_ENDOCYTIC_2 22 25 PF00928 0.621
TRG_ENDOCYTIC_2 61 64 PF00928 0.475
TRG_ER_diArg_1 42 44 PF00400 0.436

Homologs

Protein Taxonomy Sequence identity Coverage
A4HJ61 Leishmania braziliensis 77% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS