Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1M6_LEIMU

TriTrypDb:

LmxM.30.0750

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1M6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1M6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	193	197	PF00656	0.534
CLV_C14_Caspase3-7	274	278	PF00656	0.465
CLV_NRD_NRD_1	63	65	PF00675	0.551
CLV_PCSK_KEX2_1	63	65	PF00082	0.385
CLV_PCSK_SKI1_1	130	134	PF00082	0.557
CLV_PCSK_SKI1_1	190	194	PF00082	0.558
CLV_PCSK_SKI1_1	22	26	PF00082	0.524
CLV_PCSK_SKI1_1	32	36	PF00082	0.456
DEG_APCC_DBOX_1	100	108	PF00400	0.387
DOC_PP2B_LxvP_1	233	236	PF13499	0.573
DOC_USP7_MATH_1	201	205	PF00917	0.486
DOC_USP7_MATH_1	239	243	PF00917	0.672
DOC_USP7_MATH_1	261	265	PF00917	0.588
DOC_USP7_MATH_1	271	275	PF00917	0.597
DOC_USP7_UBL2_3	130	134	PF12436	0.577
DOC_USP7_UBL2_3	146	150	PF12436	0.526
DOC_USP7_UBL2_3	153	157	PF12436	0.451
DOC_WW_Pin1_4	137	142	PF00397	0.496
DOC_WW_Pin1_4	223	228	PF00397	0.476
LIG_14-3-3_CanoR_1	92	100	PF00244	0.464
LIG_Actin_WH2_2	93	110	PF00022	0.531
LIG_APCC_ABBA_1	34	39	PF00400	0.279
LIG_BRCT_BRCA1_1	139	143	PF00533	0.490
LIG_eIF4E_1	267	273	PF01652	0.470
LIG_FHA_1	1	7	PF00498	0.417
LIG_FHA_1	29	35	PF00498	0.304
LIG_FHA_2	100	106	PF00498	0.541
LIG_FHA_2	111	117	PF00498	0.394
LIG_FHA_2	191	197	PF00498	0.593
LIG_Integrin_RGD_1	194	196	PF01839	0.473
LIG_LIR_Gen_1	196	205	PF02991	0.508
LIG_LIR_Gen_1	264	275	PF02991	0.532
LIG_LIR_Nem_3	196	202	PF02991	0.441
LIG_LIR_Nem_3	264	270	PF02991	0.535
LIG_NRBOX	154	160	PF00104	0.511
LIG_PCNA_yPIPBox_3	11	25	PF02747	0.304
LIG_SH2_CRK	267	271	PF00017	0.535
LIG_SH2_NCK_1	267	271	PF00017	0.535
LIG_SH2_PTP2	231	234	PF00017	0.584
LIG_SH2_STAT3	5	8	PF00017	0.461
LIG_SH2_STAT5	18	21	PF00017	0.368
LIG_SH2_STAT5	199	202	PF00017	0.552
LIG_SH2_STAT5	231	234	PF00017	0.663
LIG_SH2_STAT5	41	44	PF00017	0.454
LIG_SH2_STAT5	5	8	PF00017	0.557
LIG_SH3_3	135	141	PF00018	0.482
LIG_SH3_3	215	221	PF00018	0.564
LIG_SH3_3	229	235	PF00018	0.687
LIG_SH3_3	70	76	PF00018	0.618
LIG_SUMO_SIM_par_1	179	186	PF11976	0.404
LIG_TRFH_1	231	235	PF08558	0.609
LIG_UBA3_1	169	177	PF00899	0.479
MOD_CK1_1	148	154	PF00069	0.507
MOD_CK1_1	182	188	PF00069	0.503
MOD_CK1_1	237	243	PF00069	0.702
MOD_CK1_1	246	252	PF00069	0.643
MOD_CK1_1	4	10	PF00069	0.476
MOD_CK2_1	110	116	PF00069	0.489
MOD_CK2_1	99	105	PF00069	0.482
MOD_GlcNHglycan	150	153	PF01048	0.455
MOD_GlcNHglycan	187	190	PF01048	0.552
MOD_GlcNHglycan	237	240	PF01048	0.732
MOD_GlcNHglycan	245	248	PF01048	0.633
MOD_GlcNHglycan	256	259	PF01048	0.486
MOD_GlcNHglycan	263	266	PF01048	0.616
MOD_GlcNHglycan	273	276	PF01048	0.607
MOD_GlcNHglycan	93	96	PF01048	0.415
MOD_GSK3_1	179	186	PF00069	0.441
MOD_GSK3_1	197	204	PF00069	0.353
MOD_GSK3_1	212	219	PF00069	0.506
MOD_GSK3_1	234	241	PF00069	0.641
MOD_N-GLC_1	53	58	PF02516	0.552
MOD_NEK2_1	1	6	PF00069	0.664
MOD_NEK2_1	183	188	PF00069	0.516
MOD_PIKK_1	4	10	PF00454	0.418
MOD_PKA_2	91	97	PF00069	0.506
MOD_Plk_4	1	7	PF00069	0.557
MOD_Plk_4	164	170	PF00069	0.482
MOD_ProDKin_1	137	143	PF00069	0.490
MOD_ProDKin_1	223	229	PF00069	0.478
MOD_SUMO_rev_2	140	148	PF00179	0.512
MOD_SUMO_rev_2	286	295	PF00179	0.649
TRG_ENDOCYTIC_2	199	202	PF00928	0.549
TRG_ENDOCYTIC_2	267	270	PF00928	0.536
TRG_Pf-PMV_PEXEL_1	157	161	PF00026	0.579
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.486
TRG_Pf-PMV_PEXEL_1	64	68	PF00026	0.403

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAJ7	Leptomonas seymouri	39%	100%
A0A0N1PCN3	Leptomonas seymouri	33%	82%
A0A3Q8IJW3	Leishmania donovani	83%	100%
A4HJ55	Leishmania braziliensis	65%	100%
A4I6G9	Leishmania infantum	84%	100%
Q9BHD3	Leishmania major	84%	100%