LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B1M4_LEIMU
TriTrypDb:
LmxM.30.0730
Length:
93

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1M4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1M4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 39 43 PF00082 0.583
CLV_PCSK_SKI1_1 89 93 PF00082 0.454
DOC_MAPK_gen_1 46 53 PF00069 0.602
DOC_PP2B_LxvP_1 14 17 PF13499 0.594
DOC_PP4_FxxP_1 6 9 PF00568 0.585
DOC_PP4_FxxP_1 80 83 PF00568 0.455
LIG_14-3-3_CterR_2 89 93 PF00244 0.468
LIG_BIR_II_1 1 5 PF00653 0.656
LIG_BIR_III_4 75 79 PF00653 0.459
LIG_BRCT_BRCA1_1 2 6 PF00533 0.510
LIG_LIR_Apic_2 3 9 PF02991 0.545
LIG_LIR_Apic_2 77 83 PF02991 0.489
LIG_SH2_STAT3 35 38 PF00017 0.463
LIG_SH3_3 12 18 PF00018 0.529
MOD_GSK3_1 55 62 PF00069 0.446
MOD_NEK2_1 53 58 PF00069 0.468
MOD_NEK2_1 59 64 PF00069 0.489
MOD_NEK2_1 84 89 PF00069 0.444
MOD_PIKK_1 17 23 PF00454 0.556
MOD_PKA_1 46 52 PF00069 0.427
MOD_Plk_1 59 65 PF00069 0.400
MOD_Plk_2-3 55 61 PF00069 0.392
MOD_Plk_4 46 52 PF00069 0.508
MOD_Plk_4 59 65 PF00069 0.433

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H7P5 Leishmania donovani 77% 85%
A4HJ53 Leishmania braziliensis 44% 100%
A4I6G7 Leishmania infantum 80% 85%
Q4Q6J0 Leishmania major 68% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS