Transcription factor

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1M2_LEIMU

TriTrypDb:

LmxM.30.0710

Length:

129

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1M2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1M2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	103	107	PF00656	0.624
CLV_C14_Caspase3-7	38	42	PF00656	0.566
CLV_NRD_NRD_1	82	84	PF00675	0.645
DEG_SCF_FBW7_1	120	126	PF00400	0.489
DEG_SCF_FBW7_1	66	71	PF00400	0.468
DOC_CKS1_1	120	125	PF01111	0.610
DOC_PP2B_LxvP_1	121	124	PF13499	0.611
DOC_USP7_MATH_1	10	14	PF00917	0.473
DOC_USP7_MATH_1	124	128	PF00917	0.666
DOC_WW_Pin1_4	119	124	PF00397	0.667
DOC_WW_Pin1_4	64	69	PF00397	0.748
LIG_CtBP_PxDLS_1	24	28	PF00389	0.598
LIG_FHA_1	115	121	PF00498	0.607
LIG_FHA_1	14	20	PF00498	0.562
LIG_FHA_1	61	67	PF00498	0.580
LIG_FHA_2	36	42	PF00498	0.569
LIG_LIR_Gen_1	88	96	PF02991	0.463
LIG_LIR_Nem_3	49	54	PF02991	0.683
LIG_LYPXL_S_1	50	54	PF13949	0.566
LIG_LYPXL_yS_3	51	54	PF13949	0.566
LIG_PDZ_Class_1	124	129	PF00595	0.640
LIG_SH3_3	117	123	PF00018	0.601
LIG_SUMO_SIM_par_1	23	29	PF11976	0.625
LIG_TRAF2_1	116	119	PF00917	0.539
LIG_TRAF2_1	18	21	PF00917	0.460
MOD_CK1_1	13	19	PF00069	0.498
MOD_CK1_1	29	35	PF00069	0.643
MOD_CK1_1	61	67	PF00069	0.677
MOD_CK1_1	77	83	PF00069	0.492
MOD_CK2_1	2	8	PF00069	0.569
MOD_GlcNHglycan	12	15	PF01048	0.570
MOD_GlcNHglycan	126	129	PF01048	0.686
MOD_GlcNHglycan	3	7	PF01048	0.579
MOD_GlcNHglycan	55	58	PF01048	0.673
MOD_GlcNHglycan	63	66	PF01048	0.612
MOD_GlcNHglycan	76	79	PF01048	0.578
MOD_GSK3_1	100	107	PF00069	0.700
MOD_GSK3_1	119	126	PF00069	0.534
MOD_GSK3_1	60	67	PF00069	0.739
MOD_N-GLC_1	46	51	PF02516	0.598
MOD_NEK2_1	2	7	PF00069	0.509
MOD_NEK2_1	58	63	PF00069	0.716
MOD_NEK2_2	46	51	PF00069	0.565
MOD_PIKK_1	114	120	PF00454	0.603
MOD_PIKK_1	77	83	PF00454	0.475
MOD_Plk_1	32	38	PF00069	0.580
MOD_Plk_1	46	52	PF00069	0.451
MOD_Plk_1	58	64	PF00069	0.654
MOD_Plk_4	46	52	PF00069	0.565
MOD_ProDKin_1	119	125	PF00069	0.668
MOD_ProDKin_1	64	70	PF00069	0.747
TRG_ENDOCYTIC_2	51	54	PF00928	0.579
TRG_ENDOCYTIC_2	89	92	PF00928	0.523

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IG87	Leishmania donovani	84%	100%
A4HJ49	Leishmania braziliensis	52%	100%
A4I6G5	Leishmania infantum	84%	100%
Q9BHG5	Leishmania major	81%	100%