Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial RNA binding protein, putative

Species:

Leishmania mexicana

UniProt:

E9B1L5_LEIMU

TriTrypDb:

LmxM.30.0640

Length:

924

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1L5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1L5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	350	354	PF00656	0.686
CLV_C14_Caspase3-7	47	51	PF00656	0.438
CLV_MEL_PAP_1	902	908	PF00089	0.387
CLV_NRD_NRD_1	111	113	PF00675	0.631
CLV_NRD_NRD_1	181	183	PF00675	0.500
CLV_NRD_NRD_1	194	196	PF00675	0.509
CLV_NRD_NRD_1	204	206	PF00675	0.365
CLV_NRD_NRD_1	274	276	PF00675	0.634
CLV_NRD_NRD_1	486	488	PF00675	0.438
CLV_NRD_NRD_1	630	632	PF00675	0.430
CLV_NRD_NRD_1	887	889	PF00675	0.459
CLV_NRD_NRD_1	904	906	PF00675	0.331
CLV_PCSK_KEX2_1	111	113	PF00082	0.621
CLV_PCSK_KEX2_1	181	183	PF00082	0.451
CLV_PCSK_KEX2_1	204	206	PF00082	0.390
CLV_PCSK_KEX2_1	273	275	PF00082	0.618
CLV_PCSK_KEX2_1	486	488	PF00082	0.436
CLV_PCSK_KEX2_1	630	632	PF00082	0.444
CLV_PCSK_KEX2_1	887	889	PF00082	0.459
CLV_PCSK_KEX2_1	904	906	PF00082	0.331
CLV_PCSK_PC7_1	883	889	PF00082	0.440
CLV_PCSK_SKI1_1	111	115	PF00082	0.653
CLV_PCSK_SKI1_1	190	194	PF00082	0.371
CLV_PCSK_SKI1_1	258	262	PF00082	0.390
CLV_PCSK_SKI1_1	274	278	PF00082	0.471
CLV_PCSK_SKI1_1	404	408	PF00082	0.439
CLV_PCSK_SKI1_1	577	581	PF00082	0.322
CLV_PCSK_SKI1_1	713	717	PF00082	0.541
CLV_PCSK_SKI1_1	753	757	PF00082	0.440
CLV_PCSK_SKI1_1	768	772	PF00082	0.470
CLV_PCSK_SKI1_1	773	777	PF00082	0.295
CLV_PCSK_SKI1_1	836	840	PF00082	0.499
CLV_PCSK_SKI1_1	920	924	PF00082	0.564
DEG_APCC_DBOX_1	121	129	PF00400	0.373
DEG_APCC_DBOX_1	181	189	PF00400	0.385
DEG_APCC_DBOX_1	882	890	PF00400	0.494
DEG_Nend_UBRbox_1	1	4	PF02207	0.616
DEG_SPOP_SBC_1	367	371	PF00917	0.729
DOC_CDC14_PxL_1	526	534	PF14671	0.479
DOC_CKS1_1	135	140	PF01111	0.587
DOC_CYCLIN_yCln2_LP_2	101	107	PF00134	0.676
DOC_CYCLIN_yCln2_LP_2	509	515	PF00134	0.532
DOC_CYCLIN_yCln2_LP_2	524	530	PF00134	0.322
DOC_MAPK_gen_1	111	119	PF00069	0.639
DOC_MAPK_gen_1	204	210	PF00069	0.397
DOC_MAPK_gen_1	216	225	PF00069	0.439
DOC_MAPK_gen_1	630	637	PF00069	0.560
DOC_MAPK_gen_1	641	648	PF00069	0.481
DOC_MAPK_gen_1	887	897	PF00069	0.480
DOC_MAPK_MEF2A_6	398	405	PF00069	0.438
DOC_MAPK_MEF2A_6	519	528	PF00069	0.527
DOC_MAPK_MEF2A_6	535	543	PF00069	0.320
DOC_MAPK_MEF2A_6	891	899	PF00069	0.557
DOC_MAPK_NFAT4_5	398	406	PF00069	0.472
DOC_MAPK_RevD_3	99	112	PF00069	0.631
DOC_PP1_RVXF_1	422	429	PF00149	0.378
DOC_PP1_SILK_1	794	799	PF00149	0.212
DOC_PP2B_LxvP_1	101	104	PF13499	0.703
DOC_PP2B_LxvP_1	509	512	PF13499	0.509
DOC_PP2B_LxvP_1	524	527	PF13499	0.293
DOC_USP7_MATH_1	267	271	PF00917	0.513
DOC_USP7_MATH_1	354	358	PF00917	0.679
DOC_USP7_MATH_1	452	456	PF00917	0.707
DOC_USP7_MATH_1	729	733	PF00917	0.507
DOC_USP7_UBL2_3	453	457	PF12436	0.694
DOC_USP7_UBL2_3	577	581	PF12436	0.484
DOC_WW_Pin1_4	134	139	PF00397	0.585
DOC_WW_Pin1_4	161	166	PF00397	0.605
DOC_WW_Pin1_4	301	306	PF00397	0.576
DOC_WW_Pin1_4	358	363	PF00397	0.714
DOC_WW_Pin1_4	368	373	PF00397	0.684
DOC_WW_Pin1_4	57	62	PF00397	0.701
DOC_WW_Pin1_4	734	739	PF00397	0.577
DOC_WW_Pin1_4	813	818	PF00397	0.602
DOC_WW_Pin1_4	881	886	PF00397	0.452
LIG_14-3-3_CanoR_1	195	201	PF00244	0.537
LIG_14-3-3_CanoR_1	297	305	PF00244	0.417
LIG_14-3-3_CanoR_1	336	341	PF00244	0.520
LIG_14-3-3_CanoR_1	35	43	PF00244	0.658
LIG_14-3-3_CanoR_1	366	372	PF00244	0.598
LIG_14-3-3_CanoR_1	5	14	PF00244	0.504
LIG_14-3-3_CanoR_1	545	555	PF00244	0.480
LIG_14-3-3_CanoR_1	78	82	PF00244	0.671
LIG_14-3-3_CanoR_1	850	860	PF00244	0.510
LIG_Actin_WH2_2	411	426	PF00022	0.470
LIG_APCC_ABBA_1	756	761	PF00400	0.441
LIG_BIR_III_2	58	62	PF00653	0.584
LIG_Clathr_ClatBox_1	102	106	PF01394	0.428
LIG_DLG_GKlike_1	336	344	PF00625	0.546
LIG_FHA_1	1	7	PF00498	0.644
LIG_FHA_1	124	130	PF00498	0.493
LIG_FHA_1	140	146	PF00498	0.426
LIG_FHA_1	225	231	PF00498	0.553
LIG_FHA_1	242	248	PF00498	0.485
LIG_FHA_1	279	285	PF00498	0.360
LIG_FHA_1	391	397	PF00498	0.359
LIG_FHA_1	504	510	PF00498	0.360
LIG_FHA_1	672	678	PF00498	0.398
LIG_FHA_1	837	843	PF00498	0.421
LIG_FHA_2	135	141	PF00498	0.584
LIG_FHA_2	197	203	PF00498	0.549
LIG_FHA_2	602	608	PF00498	0.480
LIG_FHA_2	775	781	PF00498	0.480
LIG_FHA_2	854	860	PF00498	0.432
LIG_LIR_Gen_1	142	152	PF02991	0.402
LIG_LIR_Gen_1	328	338	PF02991	0.525
LIG_LIR_Gen_1	497	505	PF02991	0.500
LIG_LIR_Gen_1	596	602	PF02991	0.523
LIG_LIR_Gen_1	629	637	PF02991	0.423
LIG_LIR_Gen_1	737	748	PF02991	0.501
LIG_LIR_Gen_1	761	770	PF02991	0.482
LIG_LIR_Gen_1	780	788	PF02991	0.275
LIG_LIR_Nem_3	142	147	PF02991	0.409
LIG_LIR_Nem_3	497	502	PF02991	0.506
LIG_LIR_Nem_3	596	601	PF02991	0.471
LIG_LIR_Nem_3	737	743	PF02991	0.699
LIG_LIR_Nem_3	757	762	PF02991	0.273
LIG_LIR_Nem_3	780	784	PF02991	0.393
LIG_LYPXL_yS_3	686	689	PF13949	0.468
LIG_NRBOX	536	542	PF00104	0.488
LIG_PCNA_yPIPBox_3	556	565	PF02747	0.486
LIG_Pex14_2	598	602	PF04695	0.479
LIG_Pex14_2	762	766	PF04695	0.432
LIG_PTB_Apo_2	260	267	PF02174	0.502
LIG_PTB_Apo_2	422	429	PF02174	0.402
LIG_SH2_CRK	397	401	PF00017	0.486
LIG_SH2_CRK	571	575	PF00017	0.480
LIG_SH2_CRK	7	11	PF00017	0.538
LIG_SH2_CRK	794	798	PF00017	0.397
LIG_SH2_GRB2like	144	147	PF00017	0.522
LIG_SH2_PTP2	144	147	PF00017	0.522
LIG_SH2_SRC	88	91	PF00017	0.692
LIG_SH2_STAP1	7	11	PF00017	0.651
LIG_SH2_STAT3	151	154	PF00017	0.538
LIG_SH2_STAT5	144	147	PF00017	0.429
LIG_SH2_STAT5	151	154	PF00017	0.408
LIG_SH2_STAT5	175	178	PF00017	0.463
LIG_SH2_STAT5	234	237	PF00017	0.473
LIG_SH2_STAT5	764	767	PF00017	0.370
LIG_SH2_STAT5	88	91	PF00017	0.692
LIG_SH2_STAT5	898	901	PF00017	0.408
LIG_SH2_STAT5	918	921	PF00017	0.279
LIG_SH3_3	227	233	PF00018	0.517
LIG_SH3_3	474	480	PF00018	0.550
LIG_SH3_3	524	530	PF00018	0.490
LIG_SH3_3	681	687	PF00018	0.432
LIG_SH3_4	453	460	PF00018	0.690
LIG_SUMO_SIM_anti_2	221	227	PF11976	0.333
LIG_SUMO_SIM_anti_2	497	504	PF11976	0.365
LIG_SUMO_SIM_par_1	206	212	PF11976	0.496
LIG_SUMO_SIM_par_1	695	701	PF11976	0.250
LIG_TRAF2_1	44	47	PF00917	0.725
LIG_TRAF2_1	709	712	PF00917	0.573
LIG_TYR_ITIM	684	689	PF00017	0.522
LIG_UBA3_1	400	407	PF00899	0.366
LIG_UBA3_1	537	542	PF00899	0.339
LIG_UBA3_1	676	683	PF00899	0.431
LIG_UBA3_1	765	773	PF00899	0.482
LIG_UBA3_1	783	790	PF00899	0.500
LIG_WRC_WIRS_1	287	292	PF05994	0.526
MOD_CDC14_SPxK_1	304	307	PF00782	0.612
MOD_CDC14_SPxK_1	884	887	PF00782	0.499
MOD_CDK_SPK_2	734	739	PF00069	0.514
MOD_CDK_SPxK_1	301	307	PF00069	0.604
MOD_CDK_SPxK_1	881	887	PF00069	0.511
MOD_CDK_SPxxK_3	881	888	PF00069	0.446
MOD_CK1_1	118	124	PF00069	0.389
MOD_CK1_1	166	172	PF00069	0.654
MOD_CK1_1	241	247	PF00069	0.457
MOD_CK1_1	285	291	PF00069	0.508
MOD_CK1_1	371	377	PF00069	0.794
MOD_CK1_1	389	395	PF00069	0.400
MOD_CK1_1	440	446	PF00069	0.698
MOD_CK1_1	460	466	PF00069	0.460
MOD_CK1_1	549	555	PF00069	0.508
MOD_CK1_1	80	86	PF00069	0.721
MOD_CK1_1	849	855	PF00069	0.512
MOD_CK1_1	908	914	PF00069	0.553
MOD_CK2_1	183	189	PF00069	0.588
MOD_CK2_1	196	202	PF00069	0.514
MOD_CK2_1	336	342	PF00069	0.528
MOD_CK2_1	440	446	PF00069	0.731
MOD_CK2_1	460	466	PF00069	0.679
MOD_CK2_1	601	607	PF00069	0.482
MOD_GlcNHglycan	185	188	PF01048	0.615
MOD_GlcNHglycan	189	193	PF01048	0.554
MOD_GlcNHglycan	269	272	PF01048	0.577
MOD_GlcNHglycan	37	40	PF01048	0.630
MOD_GlcNHglycan	439	442	PF01048	0.682
MOD_GlcNHglycan	462	465	PF01048	0.462
MOD_GlcNHglycan	515	518	PF01048	0.590
MOD_GlcNHglycan	915	918	PF01048	0.472
MOD_GlcNHglycan	92	95	PF01048	0.621
MOD_GSK3_1	278	285	PF00069	0.449
MOD_GSK3_1	314	321	PF00069	0.551
MOD_GSK3_1	325	332	PF00069	0.516
MOD_GSK3_1	354	361	PF00069	0.673
MOD_GSK3_1	367	374	PF00069	0.647
MOD_GSK3_1	386	393	PF00069	0.456
MOD_GSK3_1	440	447	PF00069	0.552
MOD_GSK3_1	5	12	PF00069	0.554
MOD_GSK3_1	511	518	PF00069	0.533
MOD_GSK3_1	544	551	PF00069	0.396
MOD_GSK3_1	812	819	PF00069	0.470
MOD_GSK3_1	846	853	PF00069	0.501
MOD_LATS_1	546	552	PF00433	0.521
MOD_N-GLC_1	145	150	PF02516	0.465
MOD_N-GLC_2	262	264	PF02516	0.418
MOD_NEK2_1	14	19	PF00069	0.599
MOD_NEK2_1	147	152	PF00069	0.467
MOD_NEK2_1	188	193	PF00069	0.530
MOD_NEK2_1	238	243	PF00069	0.423
MOD_NEK2_1	296	301	PF00069	0.529
MOD_NEK2_1	314	319	PF00069	0.386
MOD_NEK2_1	329	334	PF00069	0.428
MOD_NEK2_1	387	392	PF00069	0.566
MOD_NEK2_1	513	518	PF00069	0.480
MOD_NEK2_1	601	606	PF00069	0.400
MOD_NEK2_1	670	675	PF00069	0.396
MOD_NEK2_1	692	697	PF00069	0.472
MOD_NEK2_1	784	789	PF00069	0.369
MOD_NEK2_1	826	831	PF00069	0.564
MOD_NEK2_1	834	839	PF00069	0.526
MOD_NEK2_1	846	851	PF00069	0.288
MOD_NEK2_2	419	424	PF00069	0.511
MOD_NEK2_2	754	759	PF00069	0.398
MOD_PIKK_1	296	302	PF00454	0.544
MOD_PIKK_1	5	11	PF00454	0.555
MOD_PIKK_1	546	552	PF00454	0.528
MOD_PIKK_1	80	86	PF00454	0.676
MOD_PIKK_1	816	822	PF00454	0.575
MOD_PK_1	457	463	PF00069	0.742
MOD_PKA_2	14	20	PF00069	0.550
MOD_PKA_2	296	302	PF00069	0.394
MOD_PKA_2	544	550	PF00069	0.402
MOD_PKA_2	77	83	PF00069	0.525
MOD_PKA_2	849	855	PF00069	0.523
MOD_Plk_1	139	145	PF00069	0.415
MOD_Plk_1	188	194	PF00069	0.469
MOD_Plk_1	285	291	PF00069	0.550
MOD_Plk_1	419	425	PF00069	0.454
MOD_Plk_1	633	639	PF00069	0.533
MOD_Plk_1	671	677	PF00069	0.375
MOD_Plk_1	834	840	PF00069	0.453
MOD_Plk_2-3	741	747	PF00069	0.551
MOD_Plk_4	147	153	PF00069	0.477
MOD_Plk_4	196	202	PF00069	0.477
MOD_Plk_4	286	292	PF00069	0.471
MOD_Plk_4	325	331	PF00069	0.542
MOD_Plk_4	410	416	PF00069	0.443
MOD_Plk_4	479	485	PF00069	0.595
MOD_Plk_4	550	556	PF00069	0.439
MOD_Plk_4	608	614	PF00069	0.539
MOD_Plk_4	671	677	PF00069	0.408
MOD_Plk_4	754	760	PF00069	0.492
MOD_Plk_4	77	83	PF00069	0.665
MOD_Plk_4	792	798	PF00069	0.396
MOD_Plk_4	9	15	PF00069	0.447
MOD_ProDKin_1	134	140	PF00069	0.580
MOD_ProDKin_1	161	167	PF00069	0.607
MOD_ProDKin_1	301	307	PF00069	0.574
MOD_ProDKin_1	358	364	PF00069	0.717
MOD_ProDKin_1	368	374	PF00069	0.684
MOD_ProDKin_1	57	63	PF00069	0.703
MOD_ProDKin_1	734	740	PF00069	0.575
MOD_ProDKin_1	813	819	PF00069	0.595
MOD_ProDKin_1	881	887	PF00069	0.457
MOD_SUMO_for_1	306	309	PF00179	0.507
MOD_SUMO_rev_2	908	914	PF00179	0.549
TRG_DiLeu_BaEn_1	189	194	PF01217	0.543
TRG_DiLeu_BaEn_1	498	503	PF01217	0.351
TRG_DiLeu_BaEn_1	672	677	PF01217	0.509
TRG_DiLeu_BaLyEn_6	130	135	PF01217	0.391
TRG_DiLeu_BaLyEn_6	210	215	PF01217	0.405
TRG_DiLeu_BaLyEn_6	666	671	PF01217	0.514
TRG_ENDOCYTIC_2	144	147	PF00928	0.529
TRG_ENDOCYTIC_2	397	400	PF00928	0.478
TRG_ENDOCYTIC_2	632	635	PF00928	0.286
TRG_ENDOCYTIC_2	686	689	PF00928	0.452
TRG_ENDOCYTIC_2	7	10	PF00928	0.540
TRG_ENDOCYTIC_2	759	762	PF00928	0.342
TRG_ENDOCYTIC_2	794	797	PF00928	0.331
TRG_ER_diArg_1	110	112	PF00400	0.641
TRG_ER_diArg_1	180	182	PF00400	0.448
TRG_ER_diArg_1	204	206	PF00400	0.481
TRG_ER_diArg_1	272	275	PF00400	0.603
TRG_ER_diArg_1	486	489	PF00400	0.529
TRG_ER_diArg_1	630	632	PF00400	0.432
TRG_ER_diArg_1	677	680	PF00400	0.510
TRG_ER_diArg_1	886	888	PF00400	0.516
TRG_ER_diArg_1	904	906	PF00400	0.281
TRG_ER_diLys_1	920	924	PF00400	0.606
TRG_NES_CRM1_1	286	300	PF08389	0.525
TRG_NES_CRM1_1	395	409	PF08389	0.498
TRG_Pf-PMV_PEXEL_1	486	490	PF00026	0.487
TRG_Pf-PMV_PEXEL_1	887	892	PF00026	0.490
TRG_PTS2	1	10	PF00400	0.563

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P952	Leptomonas seymouri	46%	98%
A0A1X0NJ92	Trypanosomatidae	29%	100%
A0A3R7KJR2	Trypanosoma rangeli	31%	100%
A0A3S7X476	Leishmania donovani	88%	100%
A4HJ43	Leishmania braziliensis	76%	100%
A4I6F8	Leishmania infantum	88%	100%
C9ZN76	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
C9ZWW7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
Q4Q6J9	Leishmania major	87%	100%
V5D424	Trypanosoma cruzi	31%	100%