Proteophosphoglycan 5, related protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1K3_LEIMU

TriTrypDb:

LmxM.30.0530

Length:

677

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1K3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1K3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	230	234	PF00656	0.524
CLV_C14_Caspase3-7	362	366	PF00656	0.561
CLV_C14_Caspase3-7	379	383	PF00656	0.638
CLV_C14_Caspase3-7	662	666	PF00656	0.611
CLV_NRD_NRD_1	185	187	PF00675	0.532
CLV_NRD_NRD_1	280	282	PF00675	0.673
CLV_NRD_NRD_1	471	473	PF00675	0.803
CLV_NRD_NRD_1	639	641	PF00675	0.662
CLV_PCSK_FUR_1	637	641	PF00082	0.661
CLV_PCSK_KEX2_1	185	187	PF00082	0.532
CLV_PCSK_KEX2_1	268	270	PF00082	0.541
CLV_PCSK_KEX2_1	280	282	PF00082	0.579
CLV_PCSK_KEX2_1	339	341	PF00082	0.594
CLV_PCSK_KEX2_1	471	473	PF00082	0.797
CLV_PCSK_KEX2_1	639	641	PF00082	0.662
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.541
CLV_PCSK_PC1ET2_1	339	341	PF00082	0.594
CLV_PCSK_PC7_1	635	641	PF00082	0.537
CLV_PCSK_SKI1_1	157	161	PF00082	0.634
CLV_PCSK_SKI1_1	192	196	PF00082	0.660
CLV_PCSK_SKI1_1	333	337	PF00082	0.724
DEG_APCC_DBOX_1	534	542	PF00400	0.656
DEG_Nend_UBRbox_3	1	3	PF02207	0.664
DEG_SPOP_SBC_1	200	204	PF00917	0.524
DEG_SPOP_SBC_1	324	328	PF00917	0.638
DEG_SPOP_SBC_1	354	358	PF00917	0.574
DEG_SPOP_SBC_1	491	495	PF00917	0.700
DOC_CKS1_1	225	230	PF01111	0.658
DOC_CKS1_1	461	466	PF01111	0.688
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.697
DOC_MAPK_gen_1	651	659	PF00069	0.634
DOC_MAPK_MEF2A_6	652	661	PF00069	0.692
DOC_MAPK_RevD_3	254	269	PF00069	0.524
DOC_PIKK_1	128	136	PF02985	0.653
DOC_PP2B_LxvP_1	150	153	PF13499	0.608
DOC_PP2B_LxvP_1	507	510	PF13499	0.677
DOC_PP2B_LxvP_1	548	551	PF13499	0.643
DOC_PP4_FxxP_1	15	18	PF00568	0.648
DOC_PP4_FxxP_1	22	25	PF00568	0.590
DOC_PP4_FxxP_1	647	650	PF00568	0.651
DOC_SPAK_OSR1_1	314	318	PF12202	0.515
DOC_USP7_MATH_1	190	194	PF00917	0.706
DOC_USP7_MATH_1	245	249	PF00917	0.635
DOC_USP7_MATH_1	30	34	PF00917	0.668
DOC_USP7_MATH_1	325	329	PF00917	0.700
DOC_USP7_MATH_1	42	46	PF00917	0.585
DOC_USP7_MATH_1	420	424	PF00917	0.668
DOC_USP7_MATH_1	425	429	PF00917	0.623
DOC_USP7_MATH_1	440	444	PF00917	0.515
DOC_USP7_MATH_1	457	461	PF00917	0.659
DOC_USP7_MATH_1	479	483	PF00917	0.596
DOC_USP7_MATH_1	551	555	PF00917	0.657
DOC_WW_Pin1_4	201	206	PF00397	0.660
DOC_WW_Pin1_4	21	26	PF00397	0.656
DOC_WW_Pin1_4	224	229	PF00397	0.639
DOC_WW_Pin1_4	263	268	PF00397	0.674
DOC_WW_Pin1_4	273	278	PF00397	0.645
DOC_WW_Pin1_4	302	307	PF00397	0.617
DOC_WW_Pin1_4	35	40	PF00397	0.688
DOC_WW_Pin1_4	384	389	PF00397	0.676
DOC_WW_Pin1_4	399	404	PF00397	0.577
DOC_WW_Pin1_4	45	50	PF00397	0.641
DOC_WW_Pin1_4	455	460	PF00397	0.731
DOC_WW_Pin1_4	472	477	PF00397	0.532
DOC_WW_Pin1_4	494	499	PF00397	0.566
DOC_WW_Pin1_4	502	507	PF00397	0.709
DOC_WW_Pin1_4	510	515	PF00397	0.593
DOC_WW_Pin1_4	533	538	PF00397	0.619
DOC_WW_Pin1_4	563	568	PF00397	0.696
DOC_WW_Pin1_4	570	575	PF00397	0.665
DOC_WW_Pin1_4	624	629	PF00397	0.618
DOC_WW_Pin1_4	665	670	PF00397	0.593
DOC_WW_Pin1_4	76	81	PF00397	0.746
DOC_WW_Pin1_4	91	96	PF00397	0.546
LIG_14-3-3_CanoR_1	185	190	PF00244	0.630
LIG_14-3-3_CanoR_1	288	297	PF00244	0.682
LIG_14-3-3_CanoR_1	314	322	PF00244	0.599
LIG_14-3-3_CanoR_1	355	363	PF00244	0.598
LIG_14-3-3_CanoR_1	471	476	PF00244	0.702
LIG_14-3-3_CanoR_1	592	599	PF00244	0.640
LIG_14-3-3_CanoR_1	639	643	PF00244	0.661
LIG_14-3-3_CanoR_1	84	93	PF00244	0.668
LIG_APCC_ABBA_1	389	394	PF00400	0.698
LIG_BRCT_BRCA1_1	431	435	PF00533	0.687
LIG_CSL_BTD_1	92	95	PF09270	0.706
LIG_CtBP_PxDLS_1	262	266	PF00389	0.579
LIG_FHA_1	114	120	PF00498	0.694
LIG_FHA_1	253	259	PF00498	0.582
LIG_FHA_1	274	280	PF00498	0.593
LIG_FHA_1	292	298	PF00498	0.712
LIG_FHA_1	356	362	PF00498	0.616
LIG_FHA_1	522	528	PF00498	0.634
LIG_FHA_1	54	60	PF00498	0.648
LIG_FHA_1	6	12	PF00498	0.701
LIG_FHA_1	63	69	PF00498	0.670
LIG_FHA_2	162	168	PF00498	0.691
LIG_FHA_2	660	666	PF00498	0.565
LIG_LIR_Apic_2	13	18	PF02991	0.654
LIG_LIR_Gen_1	248	258	PF02991	0.546
LIG_LIR_Nem_3	248	253	PF02991	0.600
LIG_LIR_Nem_3	346	350	PF02991	0.713
LIG_LIR_Nem_3	433	439	PF02991	0.633
LIG_MLH1_MIPbox_1	432	436	PF16413	0.502
LIG_Pex14_2	15	19	PF04695	0.511
LIG_SH3_3	150	156	PF00018	0.651
LIG_SH3_3	222	228	PF00018	0.646
LIG_SH3_3	300	306	PF00018	0.712
LIG_SH3_3	473	479	PF00018	0.529
LIG_SH3_3	495	501	PF00018	0.753
LIG_SH3_3	531	537	PF00018	0.638
LIG_SH3_3	561	567	PF00018	0.663
LIG_SH3_3	622	628	PF00018	0.639
LIG_SH3_3	69	75	PF00018	0.672
LIG_SUMO_SIM_anti_2	445	451	PF11976	0.646
LIG_SUMO_SIM_par_1	227	233	PF11976	0.526
LIG_SUMO_SIM_par_1	252	257	PF11976	0.551
LIG_SUMO_SIM_par_1	261	266	PF11976	0.553
LIG_TRAF2_1	163	166	PF00917	0.751
LIG_TRAF2_1	393	396	PF00917	0.533
LIG_TRAF2_1	450	453	PF00917	0.713
LIG_UBA3_1	642	651	PF00899	0.644
LIG_WRC_WIRS_1	344	349	PF05994	0.712
LIG_WRC_WIRS_1	52	57	PF05994	0.660
LIG_WW_3	311	315	PF00397	0.649
MOD_CDC14_SPxK_1	266	269	PF00782	0.676
MOD_CDC14_SPxK_1	48	51	PF00782	0.719
MOD_CDK_SPK_2	263	268	PF00069	0.536
MOD_CDK_SPK_2	472	477	PF00069	0.698
MOD_CDK_SPxK_1	263	269	PF00069	0.675
MOD_CDK_SPxK_1	45	51	PF00069	0.724
MOD_CDK_SPxxK_3	273	280	PF00069	0.544
MOD_CK1_1	120	126	PF00069	0.713
MOD_CK1_1	252	258	PF00069	0.506
MOD_CK1_1	273	279	PF00069	0.627
MOD_CK1_1	287	293	PF00069	0.616
MOD_CK1_1	318	324	PF00069	0.667
MOD_CK1_1	328	334	PF00069	0.729
MOD_CK1_1	33	39	PF00069	0.694
MOD_CK1_1	353	359	PF00069	0.771
MOD_CK1_1	442	448	PF00069	0.506
MOD_CK1_1	45	51	PF00069	0.647
MOD_CK1_1	460	466	PF00069	0.678
MOD_CK1_1	475	481	PF00069	0.560
MOD_CK1_1	482	488	PF00069	0.651
MOD_CK1_1	54	60	PF00069	0.613
MOD_CK1_1	554	560	PF00069	0.742
MOD_CK1_1	605	611	PF00069	0.724
MOD_CK1_1	612	618	PF00069	0.685
MOD_CK1_1	62	68	PF00069	0.575
MOD_CK1_1	91	97	PF00069	0.655
MOD_CK2_1	109	115	PF00069	0.686
MOD_CK2_1	122	128	PF00069	0.530
MOD_CK2_1	159	165	PF00069	0.699
MOD_CK2_1	447	453	PF00069	0.722
MOD_CK2_1	533	539	PF00069	0.659
MOD_Cter_Amidation	183	186	PF01082	0.530
MOD_GlcNHglycan	143	146	PF01048	0.651
MOD_GlcNHglycan	161	164	PF01048	0.554
MOD_GlcNHglycan	181	184	PF01048	0.532
MOD_GlcNHglycan	221	224	PF01048	0.643
MOD_GlcNHglycan	242	246	PF01048	0.705
MOD_GlcNHglycan	247	250	PF01048	0.649
MOD_GlcNHglycan	3	6	PF01048	0.602
MOD_GlcNHglycan	32	35	PF01048	0.668
MOD_GlcNHglycan	379	382	PF01048	0.697
MOD_GlcNHglycan	417	421	PF01048	0.615
MOD_GlcNHglycan	431	435	PF01048	0.559
MOD_GlcNHglycan	442	445	PF01048	0.605
MOD_GlcNHglycan	494	497	PF01048	0.757
MOD_GlcNHglycan	557	560	PF01048	0.718
MOD_GlcNHglycan	615	618	PF01048	0.697
MOD_GSK3_1	1	8	PF00069	0.667
MOD_GSK3_1	109	116	PF00069	0.692
MOD_GSK3_1	199	206	PF00069	0.686
MOD_GSK3_1	241	248	PF00069	0.694
MOD_GSK3_1	252	259	PF00069	0.566
MOD_GSK3_1	26	33	PF00069	0.714
MOD_GSK3_1	271	278	PF00069	0.577
MOD_GSK3_1	280	287	PF00069	0.688
MOD_GSK3_1	302	309	PF00069	0.642
MOD_GSK3_1	324	331	PF00069	0.694
MOD_GSK3_1	350	357	PF00069	0.767
MOD_GSK3_1	359	366	PF00069	0.665
MOD_GSK3_1	395	402	PF00069	0.672
MOD_GSK3_1	416	423	PF00069	0.655
MOD_GSK3_1	425	432	PF00069	0.547
MOD_GSK3_1	435	442	PF00069	0.572
MOD_GSK3_1	463	470	PF00069	0.689
MOD_GSK3_1	471	478	PF00069	0.620
MOD_GSK3_1	482	489	PF00069	0.632
MOD_GSK3_1	490	497	PF00069	0.653
MOD_GSK3_1	51	58	PF00069	0.552
MOD_GSK3_1	551	558	PF00069	0.613
MOD_GSK3_1	588	595	PF00069	0.655
MOD_GSK3_1	59	66	PF00069	0.617
MOD_GSK3_1	601	608	PF00069	0.585
MOD_GSK3_1	609	616	PF00069	0.646
MOD_GSK3_1	659	666	PF00069	0.744
MOD_GSK3_1	667	674	PF00069	0.757
MOD_GSK3_1	84	91	PF00069	0.810
MOD_N-GLC_1	403	408	PF02516	0.673
MOD_N-GLC_1	472	477	PF02516	0.724
MOD_NEK2_1	159	164	PF00069	0.677
MOD_NEK2_1	241	246	PF00069	0.661
MOD_NEK2_1	256	261	PF00069	0.588
MOD_NEK2_1	315	320	PF00069	0.649
MOD_NEK2_1	363	368	PF00069	0.591
MOD_NEK2_1	415	420	PF00069	0.557
MOD_NEK2_1	430	435	PF00069	0.699
MOD_NEK2_1	492	497	PF00069	0.664
MOD_NEK2_1	55	60	PF00069	0.692
MOD_NEK2_1	555	560	PF00069	0.601
MOD_NEK2_1	586	591	PF00069	0.815
MOD_NEK2_1	602	607	PF00069	0.485
MOD_NEK2_2	190	195	PF00069	0.655
MOD_PIKK_1	306	312	PF00454	0.587
MOD_PIKK_1	326	332	PF00454	0.617
MOD_PIKK_1	42	48	PF00454	0.732
MOD_PIKK_1	448	454	PF00454	0.666
MOD_PIKK_1	592	598	PF00454	0.629
MOD_PKA_1	185	191	PF00069	0.523
MOD_PKA_1	280	286	PF00069	0.594
MOD_PKA_1	471	477	PF00069	0.716
MOD_PKA_2	120	126	PF00069	0.735
MOD_PKA_2	184	190	PF00069	0.630
MOD_PKA_2	279	285	PF00069	0.693
MOD_PKA_2	287	293	PF00069	0.715
MOD_PKA_2	354	360	PF00069	0.668
MOD_PKA_2	377	383	PF00069	0.666
MOD_PKA_2	467	473	PF00069	0.723
MOD_PKA_2	479	485	PF00069	0.571
MOD_PKA_2	5	11	PF00069	0.711
MOD_PKA_2	638	644	PF00069	0.658
MOD_Plk_1	359	365	PF00069	0.675
MOD_Plk_1	395	401	PF00069	0.744
MOD_Plk_1	416	422	PF00069	0.696
MOD_Plk_1	609	615	PF00069	0.706
MOD_Plk_1	63	69	PF00069	0.524
MOD_Plk_2-3	161	167	PF00069	0.698
MOD_Plk_4	10	16	PF00069	0.722
MOD_Plk_4	249	255	PF00069	0.512
MOD_Plk_4	479	485	PF00069	0.651
MOD_Plk_4	55	61	PF00069	0.701
MOD_Plk_4	551	557	PF00069	0.738
MOD_Plk_4	602	608	PF00069	0.744
MOD_Plk_4	63	69	PF00069	0.626
MOD_ProDKin_1	201	207	PF00069	0.660
MOD_ProDKin_1	21	27	PF00069	0.658
MOD_ProDKin_1	224	230	PF00069	0.640
MOD_ProDKin_1	263	269	PF00069	0.675
MOD_ProDKin_1	273	279	PF00069	0.648
MOD_ProDKin_1	302	308	PF00069	0.615
MOD_ProDKin_1	35	41	PF00069	0.687
MOD_ProDKin_1	384	390	PF00069	0.677
MOD_ProDKin_1	399	405	PF00069	0.579
MOD_ProDKin_1	45	51	PF00069	0.640
MOD_ProDKin_1	455	461	PF00069	0.733
MOD_ProDKin_1	472	478	PF00069	0.531
MOD_ProDKin_1	494	500	PF00069	0.567
MOD_ProDKin_1	502	508	PF00069	0.711
MOD_ProDKin_1	510	516	PF00069	0.592
MOD_ProDKin_1	533	539	PF00069	0.659
MOD_ProDKin_1	563	569	PF00069	0.699
MOD_ProDKin_1	570	576	PF00069	0.661
MOD_ProDKin_1	624	630	PF00069	0.618
MOD_ProDKin_1	665	671	PF00069	0.597
MOD_ProDKin_1	76	82	PF00069	0.747
MOD_ProDKin_1	91	97	PF00069	0.546
TRG_DiLeu_BaEn_1	396	401	PF01217	0.532
TRG_DiLeu_BaEn_4	166	172	PF01217	0.736
TRG_ER_diArg_1	279	281	PF00400	0.596
TRG_ER_diArg_1	527	530	PF00400	0.684
TRG_Pf-PMV_PEXEL_1	298	302	PF00026	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ISE9	Leishmania donovani	84%	100%
A4HJ31	Leishmania braziliensis	57%	99%
A4I6L0	Leishmania infantum	85%	100%
Q4Q6L0	Leishmania major	82%	100%