LeishMANIAdb
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Fe2OG dioxygenase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Fe2OG dioxygenase domain-containing protein
Gene product:
2OG-Fe(II) oxygenase superfamily, putative
Species:
Leishmania mexicana
UniProt:
E9B1H8_LEIMU
TriTrypDb:
LmxM.30.0270
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1H8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1H8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 37 39 PF00675 0.428
CLV_NRD_NRD_1 75 77 PF00675 0.467
CLV_PCSK_KEX2_1 75 77 PF00082 0.467
CLV_PCSK_SKI1_1 128 132 PF00082 0.584
DEG_APCC_DBOX_1 127 135 PF00400 0.315
DOC_MAPK_gen_1 123 133 PF00069 0.336
DOC_MAPK_gen_1 38 48 PF00069 0.371
DOC_PP4_FxxP_1 4 7 PF00568 0.433
DOC_USP7_MATH_1 32 36 PF00917 0.529
LIG_14-3-3_CanoR_1 75 83 PF00244 0.513
LIG_Actin_WH2_2 127 144 PF00022 0.338
LIG_Actin_WH2_2 59 77 PF00022 0.465
LIG_FHA_1 15 21 PF00498 0.428
LIG_IRF3_LxIS_1 104 110 PF10401 0.338
LIG_MYND_1 3 7 PF01753 0.435
LIG_NRBOX 117 123 PF00104 0.476
LIG_Pex14_2 44 48 PF04695 0.355
LIG_SH2_SRC 92 95 PF00017 0.322
LIG_SH2_STAP1 88 92 PF00017 0.475
LIG_SH2_STAT5 42 45 PF00017 0.560
MOD_CK2_1 107 113 PF00069 0.430
MOD_GlcNHglycan 76 79 PF01048 0.398
MOD_NEK2_1 107 112 PF00069 0.339
MOD_NEK2_1 37 42 PF00069 0.398
MOD_NEK2_1 74 79 PF00069 0.440
MOD_PKA_2 37 43 PF00069 0.392
MOD_PKA_2 74 80 PF00069 0.436
MOD_Plk_1 92 98 PF00069 0.325
MOD_Plk_4 14 20 PF00069 0.438
MOD_SUMO_for_1 122 125 PF00179 0.361
TRG_ER_diArg_1 29 32 PF00400 0.358
TRG_ER_diArg_1 74 76 PF00400 0.465

Homologs

Protein Taxonomy Sequence identity Coverage
A4HJ01 Leishmania braziliensis 63% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS